메뉴 건너뛰기




Volumn 36, Issue 5, 2015, Pages 297-309

Amyloid biomarkers in Alzheimer's disease

Author keywords

Alzheimer's disease; biomarker; cerebrospinal fluid; positron emission tomography (PET); amyloid (A )

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); BIOLOGICAL MARKER; PEPTIDE FRAGMENT;

EID: 84937758712     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2015.03.002     Document Type: Article
Times cited : (387)

References (140)
  • 1
    • 0019153066 scopus 로고
    • Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts)
    • G.G. Glenner Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts) N. Engl. J. Med. 302 1980 1283 1292
    • (1980) N. Engl. J. Med. , vol.302 , pp. 1283-1292
    • Glenner, G.G.1
  • 2
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • K. Blennow et al. Alzheimer's disease Lancet 368 2006 387 403
    • (2006) Lancet , vol.368 , pp. 387-403
    • Blennow, K.1
  • 3
    • 67651180986 scopus 로고    scopus 로고
    • The amyloid hypothesis for Alzheimer's disease: a critical reappraisal
    • J. Hardy The amyloid hypothesis for Alzheimer's disease: a critical reappraisal J. Neurochem. 110 2009 1129 1134
    • (2009) J. Neurochem. , vol.110 , pp. 1129-1134
    • Hardy, J.1
  • 4
    • 84890446929 scopus 로고    scopus 로고
    • Biomarkers in amyloid-beta immunotherapy trials in Alzheimer's disease
    • K. Blennow et al. Biomarkers in amyloid-beta immunotherapy trials in Alzheimer's disease Neuropsychopharmacology 39 2014 189 201
    • (2014) Neuropsychopharmacology , vol.39 , pp. 189-201
    • Blennow, K.1
  • 5
    • 84892695519 scopus 로고    scopus 로고
    • Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease
    • S. Salloway et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease N. Engl. J. Med. 370 2014 322 333
    • (2014) N. Engl. J. Med. , vol.370 , pp. 322-333
    • Salloway, S.1
  • 6
    • 84880712325 scopus 로고    scopus 로고
    • A phase 3 trial of semagacestat for treatment of Alzheimer's disease
    • R.S. Doody et al. A phase 3 trial of semagacestat for treatment of Alzheimer's disease N. Engl. J. Med. 369 2013 341 350
    • (2013) N. Engl. J. Med. , vol.369 , pp. 341-350
    • Doody, R.S.1
  • 7
    • 84892748542 scopus 로고    scopus 로고
    • Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease
    • R.S. Doody et al. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease N. Engl. J. Med. 370 2014 311 321
    • (2014) N. Engl. J. Med. , vol.370 , pp. 311-321
    • Doody, R.S.1
  • 8
    • 84892710970 scopus 로고    scopus 로고
    • Antiamyloid therapy for Alzheimer's disease - Are we on the right road?
    • E. Karran, and J. Hardy Antiamyloid therapy for Alzheimer's disease - are we on the right road? N. Engl. J. Med. 370 2014 377 378
    • (2014) N. Engl. J. Med. , vol.370 , pp. 377-378
    • Karran, E.1    Hardy, J.2
  • 9
    • 78149330220 scopus 로고    scopus 로고
    • Biomarkers in Alzheimer's disease drug development
    • K. Blennow Biomarkers in Alzheimer's disease drug development Nat. Med. 16 2010 1218 1222
    • (2010) Nat. Med. , vol.16 , pp. 1218-1222
    • Blennow, K.1
  • 10
    • 77949423619 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
    • K. Blennow et al. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease Nat. Rev. Neurol. 6 2010 131 144
    • (2010) Nat. Rev. Neurol. , vol.6 , pp. 131-144
    • Blennow, K.1
  • 11
    • 48949098573 scopus 로고    scopus 로고
    • Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial
    • L. Lannfelt et al. Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial Lancet Neurol. 7 2008 779 786
    • (2008) Lancet Neurol. , vol.7 , pp. 779-786
    • Lannfelt, L.1
  • 12
    • 84862331908 scopus 로고    scopus 로고
    • Safety, tolerability, and antibody response of active Abeta immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study
    • B. Winblad et al. Safety, tolerability, and antibody response of active Abeta immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study Lancet Neurol. 11 2012 597 604
    • (2012) Lancet Neurol. , vol.11 , pp. 597-604
    • Winblad, B.1
  • 13
    • 81255143061 scopus 로고    scopus 로고
    • Robust central reduction of amyloid-beta in humans with an orally available, non-peptidic beta-secretase inhibitor
    • P.C. May et al. Robust central reduction of amyloid-beta in humans with an orally available, non-peptidic beta-secretase inhibitor J. Neurosci. 31 2011 16507 16516
    • (2011) J. Neurosci. , vol.31 , pp. 16507-16516
    • May, P.C.1
  • 14
    • 77954239263 scopus 로고    scopus 로고
    • Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives
    • H. Hampel et al. Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives Nat. Rev. Drug Discov. 9 2010 560 574
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 560-574
    • Hampel, H.1
  • 15
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group Biomarkers and surrogate endpoints: preferred definitions and conceptual framework Clin. Pharmacol. Ther. 69 2001 89 95
    • (2001) Clin. Pharmacol. Ther. , vol.69 , pp. 89-95
  • 16
    • 0032033832 scopus 로고    scopus 로고
    • Consensus report of the Working Group on: 'Molecular and Biochemical Markers of Alzheimer's Disease'
    • The Ronald and Nancy Reagan Research Institute of the Alzheimer's Association and the National Institute on Aging Working Group
    • Anon Consensus report of the Working Group on: 'Molecular and Biochemical Markers of Alzheimer's Disease'. The Ronald and Nancy Reagan Research Institute of the Alzheimer's Association and the National Institute on Aging Working Group Neurobiol. Aging 19 1998 109 116
    • (1998) Neurobiol. Aging , vol.19 , pp. 109-116
    • Anon1
  • 17
    • 79955953179 scopus 로고    scopus 로고
    • A novel pathway for amyloid precursor protein processing
    • E. Portelius et al. A novel pathway for amyloid precursor protein processing Neurobiol. Aging 32 2011 1090 1098
    • (2011) Neurobiol. Aging , vol.32 , pp. 1090-1098
    • Portelius, E.1
  • 18
    • 49449108546 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease
    • H. Zetterberg et al. Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease Arch. Neurol. 65 2008 1102 1107
    • (2008) Arch. Neurol. , vol.65 , pp. 1102-1107
    • Zetterberg, H.1
  • 19
    • 84879149021 scopus 로고    scopus 로고
    • Evaluating amyloid-beta oligomers in cerebrospinal fluid as a biomarker for Alzheimer's disease
    • M. Holtta et al. Evaluating amyloid-beta oligomers in cerebrospinal fluid as a biomarker for Alzheimer's disease PLoS ONE 8 2013 e66381
    • (2013) PLoS ONE , vol.8
    • Holtta, M.1
  • 20
    • 84894073956 scopus 로고    scopus 로고
    • A sensitive abeta oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid
    • M.J. Savage et al. A sensitive abeta oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid J. Neurosci. 34 2014 2884 2897
    • (2014) J. Neurosci. , vol.34 , pp. 2884-2897
    • Savage, M.J.1
  • 21
    • 0026646604 scopus 로고
    • Amyloid beta-peptide is produced by cultured cells during normal metabolism
    • C. Haass et al. Amyloid beta-peptide is produced by cultured cells during normal metabolism Nature 359 1992 322 325
    • (1992) Nature , vol.359 , pp. 322-325
    • Haass, C.1
  • 22
    • 0028181396 scopus 로고
    • Soluble amyloid beta-protein is a marker of Alzheimer amyloid in brain but not in cerebrospinal fluid
    • M. Tabaton et al. Soluble amyloid beta-protein is a marker of Alzheimer amyloid in brain but not in cerebrospinal fluid Biochem. Biophys. Res. Commun. 200 1994 1598 1603
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 1598-1603
    • Tabaton, M.1
  • 23
    • 0026572465 scopus 로고
    • Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients
    • W.E. Van Nostrand et al. Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients Proc. Natl. Acad. Sci. U.S.A. 89 1992 2551 2555
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 2551-2555
    • Van Nostrand, W.E.1
  • 24
    • 0028169925 scopus 로고
    • Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43)
    • T. Iwatsubo et al. Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43) Neuron 13 1994 45 53
    • (1994) Neuron , vol.13 , pp. 45-53
    • Iwatsubo, T.1
  • 25
    • 0027258525 scopus 로고
    • The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease
    • J.T. Jarrett et al. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease Biochemistry 32 1993 4693 4697
    • (1993) Biochemistry , vol.32 , pp. 4693-4697
    • Jarrett, J.T.1
  • 26
    • 0028982454 scopus 로고
    • Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease
    • R. Motter et al. Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease Ann. Neurol. 38 1995 643 648
    • (1995) Ann. Neurol. , vol.38 , pp. 643-648
    • Motter, R.1
  • 27
    • 0141738373 scopus 로고    scopus 로고
    • CSF markers for incipient Alzheimer's disease
    • K. Blennow, and H. Hampel CSF markers for incipient Alzheimer's disease Lancet Neurol. 2 2003 605 613
    • (2003) Lancet Neurol. , vol.2 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 28
    • 0033061647 scopus 로고    scopus 로고
    • Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease
    • N. Andreasen et al. Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease Arch. Neurol. 56 1999 673 680
    • (1999) Arch. Neurol. , vol.56 , pp. 673-680
    • Andreasen, N.1
  • 29
    • 12944312683 scopus 로고    scopus 로고
    • Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology
    • A. Olsson et al. Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology Clin. Chem. 51 2005 336 345
    • (2005) Clin. Chem. , vol.51 , pp. 336-345
    • Olsson, A.1
  • 30
    • 18444393054 scopus 로고    scopus 로고
    • Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
    • J. Wiltfang et al. Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation J. Neurochem. 81 2002 481 496
    • (2002) J. Neurochem. , vol.81 , pp. 481-496
    • Wiltfang, J.1
  • 31
    • 84903703012 scopus 로고    scopus 로고
    • Mass spectrometry-based candidate reference measurement procedure for quantification of amyloid-beta in cerebrospinal fluid
    • A. Leinenbach et al. Mass spectrometry-based candidate reference measurement procedure for quantification of amyloid-beta in cerebrospinal fluid Clin. Chem. 60 2014 987 994
    • (2014) Clin. Chem. , vol.60 , pp. 987-994
    • Leinenbach, A.1
  • 32
    • 0042591226 scopus 로고    scopus 로고
    • CSF markers for pathogenic processes in Alzheimer's disease: diagnostic implications and use in clinical neurochemistry
    • K. Blennow, and E. Vanmechelen CSF markers for pathogenic processes in Alzheimer's disease: diagnostic implications and use in clinical neurochemistry Brain Res. Bull. 61 2003 235 242
    • (2003) Brain Res. Bull. , vol.61 , pp. 235-242
    • Blennow, K.1    Vanmechelen, E.2
  • 33
    • 33645775230 scopus 로고    scopus 로고
    • Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry
    • E. Portelius et al. Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry J. Proteome Res. 5 2006 1010 1016
    • (2006) J. Proteome Res. , vol.5 , pp. 1010-1016
    • Portelius, E.1
  • 34
    • 34247384609 scopus 로고    scopus 로고
    • Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment
    • O. Hansson et al. Prediction of Alzheimer's disease using the CSF Abeta42/Abeta40 ratio in patients with mild cognitive impairment Dement. Geriatr. Cogn. Disord. 23 2007 316 320
    • (2007) Dement. Geriatr. Cogn. Disord. , vol.23 , pp. 316-320
    • Hansson, O.1
  • 35
    • 84908700565 scopus 로고    scopus 로고
    • Amyloid-beta 42/40 cerebrospinal fluid concentration ratio in the diagnostics of Alzheimer's disease: validation of two novel assays
    • P. Lewczuk et al. Amyloid-beta 42/40 cerebrospinal fluid concentration ratio in the diagnostics of Alzheimer's disease: validation of two novel assays J. Alzheimers Dis. 43 2015 183 191
    • (2015) J. Alzheimers Dis. , vol.43 , pp. 183-191
    • Lewczuk, P.1
  • 36
    • 0033975837 scopus 로고    scopus 로고
    • Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
    • P.D. Mehta et al. Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease Arch. Neurol. 57 2000 100 105
    • (2000) Arch. Neurol. , vol.57 , pp. 100-105
    • Mehta, P.D.1
  • 37
    • 34247581358 scopus 로고    scopus 로고
    • Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load
    • J. Wiltfang et al. Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load J. Neurochem. 101 2007 1053 1059
    • (2007) J. Neurochem. , vol.101 , pp. 1053-1059
    • Wiltfang, J.1
  • 38
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
    • W.E. Klunk et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B Ann. Neurol. 55 2004 306 319
    • (2004) Ann. Neurol. , vol.55 , pp. 306-319
    • Klunk, W.E.1
  • 39
    • 84888177803 scopus 로고    scopus 로고
    • Cerebral amyloid PET imaging in Alzheimer's disease
    • C.R. Jack Jr et al. Cerebral amyloid PET imaging in Alzheimer's disease Acta Neuropathol. 126 2013 643 657
    • (2013) Acta Neuropathol. , vol.126 , pp. 643-657
    • Jack, Jr.C.R.1
  • 40
    • 80955137862 scopus 로고    scopus 로고
    • Amyloid imaging as a biomarker for cerebral beta-amyloidosis and risk prediction for Alzheimer dementia
    • W.E. Klunk Amyloid imaging as a biomarker for cerebral beta-amyloidosis and risk prediction for Alzheimer dementia Neurobiol. Aging 32 Suppl. 1 2011 S20 S36
    • (2011) Neurobiol. Aging , vol.32 , pp. S20-S36
    • Klunk, W.E.1
  • 41
    • 77953937194 scopus 로고    scopus 로고
    • In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18)
    • D.F. Wong et al. In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18) J. Nucl. Med. 51 2010 913 920
    • (2010) J. Nucl. Med. , vol.51 , pp. 913-920
    • Wong, D.F.1
  • 42
    • 68249141258 scopus 로고    scopus 로고
    • Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease
    • N. Nelissen et al. Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease J. Nucl. Med. 50 2009 1251 1259
    • (2009) J. Nucl. Med. , vol.50 , pp. 1251-1259
    • Nelissen, N.1
  • 43
    • 38149081191 scopus 로고    scopus 로고
    • Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism
    • C.C. Rowe et al. Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism Lancet Neurol. 7 2008 129 135
    • (2008) Lancet Neurol. , vol.7 , pp. 129-135
    • Rowe, C.C.1
  • 44
    • 84877041796 scopus 로고    scopus 로고
    • Head-to-head comparison of 11C-PiB and 18F-AZD4694 (NAV4694) for beta-amyloid imaging in aging and dementia
    • C.C. Rowe et al. Head-to-head comparison of 11C-PiB and 18F-AZD4694 (NAV4694) for beta-amyloid imaging in aging and dementia J. Nucl. Med. 54 2013 880 886
    • (2013) J. Nucl. Med. , vol.54 , pp. 880-886
    • Rowe, C.C.1
  • 45
    • 34848885454 scopus 로고    scopus 로고
    • PIB is a non-specific imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis
    • A. Lockhart et al. PIB is a non-specific imaging marker of amyloid-beta (Abeta) peptide-related cerebral amyloidosis Brain 130 2007 2607 2615
    • (2007) Brain , vol.130 , pp. 2607-2615
    • Lockhart, A.1
  • 46
    • 43849083580 scopus 로고    scopus 로고
    • Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
    • M.D. Ikonomovic et al. Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease Brain 131 2008 1630 1645
    • (2008) Brain , vol.131 , pp. 1630-1645
    • Ikonomovic, M.D.1
  • 47
    • 33947198109 scopus 로고    scopus 로고
    • Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report
    • B.J. Bacskai et al. Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report Arch. Neurol. 64 2007 431 434
    • (2007) Arch. Neurol. , vol.64 , pp. 431-434
    • Bacskai, B.J.1
  • 48
    • 84863859181 scopus 로고    scopus 로고
    • Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers
    • M. Scholl et al. Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers Neurology 79 2012 229 236
    • (2012) Neurology , vol.79 , pp. 229-236
    • Scholl, M.1
  • 49
    • 57749117469 scopus 로고    scopus 로고
    • Detection of isolated cerebrovascular beta-amyloid with Pittsburgh compound B
    • S.M. Greenberg et al. Detection of isolated cerebrovascular beta-amyloid with Pittsburgh compound B Ann. Neurol. 64 2008 587 591
    • (2008) Ann. Neurol. , vol.64 , pp. 587-591
    • Greenberg, S.M.1
  • 50
    • 76649142080 scopus 로고    scopus 로고
    • 11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage
    • J.V. Ly et al. 11C-PIB binding is increased in patients with cerebral amyloid angiopathy-related hemorrhage Neurology 74 2010 487 493
    • (2010) Neurology , vol.74 , pp. 487-493
    • Ly, J.V.1
  • 51
    • 78751546481 scopus 로고    scopus 로고
    • Use of florbetapir-PET for imaging beta-amyloid pathology
    • C.M. Clark et al. Use of florbetapir-PET for imaging beta-amyloid pathology JAMA 305 2011 275 283
    • (2011) JAMA , vol.305 , pp. 275-283
    • Clark, C.M.1
  • 52
    • 84863869296 scopus 로고    scopus 로고
    • Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-beta plaques: a prospective cohort study
    • C.M. Clark et al. Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-beta plaques: a prospective cohort study Lancet Neurol. 11 2012 669 678
    • (2012) Lancet Neurol. , vol.11 , pp. 669-678
    • Clark, C.M.1
  • 53
    • 84874222233 scopus 로고    scopus 로고
    • [(18)F]Flutemetamol PET imaging and cortical biopsy histopathology for fibrillar amyloid beta detection in living subjects with normal pressure hydrocephalus: pooled analysis of four studies
    • J.O. Rinne et al. [(18)F]Flutemetamol PET imaging and cortical biopsy histopathology for fibrillar amyloid beta detection in living subjects with normal pressure hydrocephalus: pooled analysis of four studies Acta Neuropathol. 124 2012 833 845
    • (2012) Acta Neuropathol. , vol.124 , pp. 833-845
    • Rinne, J.O.1
  • 54
    • 84921436071 scopus 로고    scopus 로고
    • Diagnostic effectiveness of quantitative [(1)(8)F]flutemetamol PET imaging for detection of fibrillar amyloid beta using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus
    • V. Leinonen et al. Diagnostic effectiveness of quantitative [(1)(8)F]flutemetamol PET imaging for detection of fibrillar amyloid beta using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus Acta Neuropathol. Commun. 2 2014 46
    • (2014) Acta Neuropathol. Commun. , vol.2 , pp. 46
    • Leinonen, V.1
  • 55
    • 0037465449 scopus 로고    scopus 로고
    • CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study
    • D. Strozyk et al. CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study Neurology 60 2003 652 656
    • (2003) Neurology , vol.60 , pp. 652-656
    • Strozyk, D.1
  • 56
    • 62449262536 scopus 로고    scopus 로고
    • Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain
    • T. Tapiola et al. Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain Arch. Neurol. 66 2009 382 389
    • (2009) Arch. Neurol. , vol.66 , pp. 382-389
    • Tapiola, T.1
  • 57
    • 79956197854 scopus 로고    scopus 로고
    • Different CSF beta-amyloid processing in Alzheimer's and Creutzfeldt-Jakob disease
    • B. Mollenhauer et al. Different CSF beta-amyloid processing in Alzheimer's and Creutzfeldt-Jakob disease J. Neural Transm. 118 2011 691 697
    • (2011) J. Neural Transm. , vol.118 , pp. 691-697
    • Mollenhauer, B.1
  • 58
    • 33644832047 scopus 로고    scopus 로고
    • Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans
    • A.M. Fagan et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans Ann. Neurol. 59 2006 512 519
    • (2006) Ann. Neurol. , vol.59 , pp. 512-519
    • Fagan, A.M.1
  • 59
    • 33947223454 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
    • A.M. Fagan et al. Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults Arch. Neurol. 64 2007 343 349
    • (2007) Arch. Neurol. , vol.64 , pp. 343-349
    • Fagan, A.M.1
  • 60
    • 77949425172 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease
    • A.M. Fagan et al. Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease EMBO Mol. Med. 1 2009 371 380
    • (2009) EMBO Mol. Med. , vol.1 , pp. 371-380
    • Fagan, A.M.1
  • 61
    • 49349092320 scopus 로고    scopus 로고
    • PET imaging of amyloid deposition in patients with mild cognitive impairment
    • A. Forsberg et al. PET imaging of amyloid deposition in patients with mild cognitive impairment Neurobiol. Aging 29 2008 1456 1465
    • (2008) Neurobiol. Aging , vol.29 , pp. 1456-1465
    • Forsberg, A.1
  • 62
    • 70350152831 scopus 로고    scopus 로고
    • Relationships between biomarkers in aging and dementia
    • W.J. Jagust et al. Relationships between biomarkers in aging and dementia Neurology 73 2009 1193 1199
    • (2009) Neurology , vol.73 , pp. 1193-1199
    • Jagust, W.J.1
  • 63
    • 69449085355 scopus 로고    scopus 로고
    • Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding
    • N. Tolboom et al. Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding J. Nucl. Med. 50 2009 1464 1470
    • (2009) J. Nucl. Med. , vol.50 , pp. 1464-1470
    • Tolboom, N.1
  • 64
    • 77949555201 scopus 로고    scopus 로고
    • Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study
    • M. Degerman Gunnarsson et al. Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study Dement. Geriatr. Cogn. Disord. 29 2010 204 212
    • (2010) Dement. Geriatr. Cogn. Disord. , vol.29 , pp. 204-212
    • Degerman Gunnarsson, M.1
  • 65
    • 79952740168 scopus 로고    scopus 로고
    • Transforming cerebrospinal fluid Abeta42 measures into calculated Pittsburgh Compound B units of brain Abeta amyloid
    • S.D. Weigand et al. Transforming cerebrospinal fluid Abeta42 measures into calculated Pittsburgh Compound B units of brain Abeta amyloid Alzheimers Dement. 7 2011 133 141
    • (2011) Alzheimers Dement. , vol.7 , pp. 133-141
    • Weigand, S.D.1
  • 66
    • 84925882292 scopus 로고    scopus 로고
    • Concordance between cerebrospinal fluid biomarkers and [11C]PIB PET in a memory clinic cohort
    • M. Zwan et al. Concordance between cerebrospinal fluid biomarkers and [11C]PIB PET in a memory clinic cohort J. Alzheimers Dis. 41 2014 801 807
    • (2014) J. Alzheimers Dis. , vol.41 , pp. 801-807
    • Zwan, M.1
  • 67
    • 84892918273 scopus 로고    scopus 로고
    • Comparing positron emission tomography imaging and cerebrospinal fluid measurements of beta-amyloid
    • S.M. Landau et al. Comparing positron emission tomography imaging and cerebrospinal fluid measurements of beta-amyloid Ann. Neurol. 74 2013 826 836
    • (2013) Ann. Neurol. , vol.74 , pp. 826-836
    • Landau, S.M.1
  • 68
    • 84907978955 scopus 로고    scopus 로고
    • Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid beta-amyloid 42: a cross-validation study against amyloid positron emission tomography
    • S. Palmqvist et al. Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid beta-amyloid 42: a cross-validation study against amyloid positron emission tomography JAMA Neurol. 71 2014 1282 1289
    • (2014) JAMA Neurol. , vol.71 , pp. 1282-1289
    • Palmqvist, S.1
  • 69
    • 77957279325 scopus 로고    scopus 로고
    • Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease
    • E. Portelius et al. Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease Acta Neuropathol. 120 2010 185 193
    • (2010) Acta Neuropathol. , vol.120 , pp. 185-193
    • Portelius, E.1
  • 70
    • 72149123967 scopus 로고    scopus 로고
    • Total and phosphorylated tau protein as biological markers of Alzheimer's disease
    • H. Hampel et al. Total and phosphorylated tau protein as biological markers of Alzheimer's disease Exp. Gerontol. 45 2010 30 40
    • (2010) Exp. Gerontol. , vol.45 , pp. 30-40
    • Hampel, H.1
  • 71
    • 73549123897 scopus 로고    scopus 로고
    • Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report
    • N.J. Cairns et al. Absence of Pittsburgh compound B detection of cerebral amyloid beta in a patient with clinical, cognitive, and cerebrospinal fluid markers of Alzheimer disease: a case report Arch. Neurol. 66 2009 1557 1562
    • (2009) Arch. Neurol. , vol.66 , pp. 1557-1562
    • Cairns, N.J.1
  • 72
    • 84927957367 scopus 로고    scopus 로고
    • Independent information from cerebrospinal fluid amyloid-beta and florbetapir imaging in Alzheimer's disease
    • N. Mattsson et al. Independent information from cerebrospinal fluid amyloid-beta and florbetapir imaging in Alzheimer's disease Brain 138 2015 772 783
    • (2015) Brain , vol.138 , pp. 772-783
    • Mattsson, N.1
  • 73
    • 84892402771 scopus 로고    scopus 로고
    • Quantitative analysis of PiB-PET with FreeSurfer ROIs
    • Y. Su et al. Quantitative analysis of PiB-PET with FreeSurfer ROIs PLoS ONE 8 2013 e73377
    • (2013) PLoS ONE , vol.8
    • Su, Y.1
  • 74
    • 84928107166 scopus 로고    scopus 로고
    • Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer's disease
    • N. Mattsson et al. Diagnostic accuracy of CSF Ab42 and florbetapir PET for Alzheimer's disease Ann. Clin. Transl. Neurol. 1 2014 534 543
    • (2014) Ann. Clin. Transl. Neurol. , vol.1 , pp. 534-543
    • Mattsson, N.1
  • 75
    • 65249159879 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
    • L.M. Shaw et al. Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects Ann. Neurol. 65 2009 403 413
    • (2009) Ann. Neurol. , vol.65 , pp. 403-413
    • Shaw, L.M.1
  • 76
    • 67651204382 scopus 로고    scopus 로고
    • CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment
    • N. Mattsson et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment JAMA 302 2009 385 393
    • (2009) JAMA , vol.302 , pp. 385-393
    • Mattsson, N.1
  • 77
    • 84875366315 scopus 로고    scopus 로고
    • Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: an update from the Alzheimer's Association Global Biomarkers Consortium
    • M.C. Carrillo et al. Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: an update from the Alzheimer's Association Global Biomarkers Consortium Alzheimers Dement. 9 2013 137 140
    • (2013) Alzheimers Dement. , vol.9 , pp. 137-140
    • Carrillo, M.C.1
  • 78
    • 84927566319 scopus 로고    scopus 로고
    • Qualification of a surrogate matrix-based absolute quantification method for amyloid-beta(4)(2) in human cerebrospinal fluid using 2D UPLC-tandem mass spectrometry
    • M. Korecka et al. Qualification of a surrogate matrix-based absolute quantification method for amyloid-beta(4)(2) in human cerebrospinal fluid using 2D UPLC-tandem mass spectrometry J. Alzheimers Dis. 41 2014 441 451
    • (2014) J. Alzheimers Dis. , vol.41 , pp. 441-451
    • Korecka, M.1
  • 79
    • 84865452551 scopus 로고    scopus 로고
    • Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid beta42
    • N. Mattsson et al. Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid beta42 Biomark. Med. 6 2012 409 417
    • (2012) Biomark. Med. , vol.6 , pp. 409-417
    • Mattsson, N.1
  • 80
    • 79960764322 scopus 로고    scopus 로고
    • The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers
    • N. Mattsson et al. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers Alzheimers Dement. 7 2011 386 395
    • (2011) Alzheimers Dement. , vol.7 , pp. 386-395
    • Mattsson, N.1
  • 81
    • 6944256515 scopus 로고    scopus 로고
    • Understanding the standardized uptake value, its methods, and implications for usage
    • J.A. Thie Understanding the standardized uptake value, its methods, and implications for usage J. Nucl. Med. 45 2004 1431 1434
    • (2004) J. Nucl. Med. , vol.45 , pp. 1431-1434
    • Thie, J.A.1
  • 82
    • 0021364348 scopus 로고
    • A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography
    • M.A. Mintun et al. A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography Ann. Neurol. 15 1984 217 327
    • (1984) Ann. Neurol. , vol.15 , pp. 217-327
    • Mintun, M.A.1
  • 83
    • 46849093845 scopus 로고    scopus 로고
    • PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease
    • J. Koivunen et al. PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease Brain 131 2008 1845 1853
    • (2008) Brain , vol.131 , pp. 1845-1853
    • Koivunen, J.1
  • 84
    • 84863418985 scopus 로고    scopus 로고
    • Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans?
    • P. Edison et al. Can target-to-pons ratio be used as a reliable method for the analysis of [11C]PIB brain scans? Neuroimage 60 2012 1716 1723
    • (2012) Neuroimage , vol.60 , pp. 1716-1723
    • Edison, P.1
  • 85
    • 84922779468 scopus 로고    scopus 로고
    • The centiloid project: standardizing quantitative amyloid plaque estimation by PET
    • W.E. Klunk et al. The centiloid project: standardizing quantitative amyloid plaque estimation by PET Alzheimers Dement. 11 2015 1 15
    • (2015) Alzheimers Dement. , vol.11 , pp. 1-15
    • Klunk, W.E.1
  • 86
    • 84881287638 scopus 로고    scopus 로고
    • Imaging markers for Alzheimer disease: which vs how
    • G.B. Frisoni et al. Imaging markers for Alzheimer disease: which vs how Neurology 81 2013 487 500
    • (2013) Neurology , vol.81 , pp. 487-500
    • Frisoni, G.B.1
  • 87
    • 70349582720 scopus 로고    scopus 로고
    • Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study
    • A. Okello et al. Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study Neurology 73 2009 754 760
    • (2009) Neurology , vol.73 , pp. 754-760
    • Okello, A.1
  • 88
    • 78049477126 scopus 로고    scopus 로고
    • Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease
    • C.R. Jack Jr et al. Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease Brain 133 2010 3336 3348
    • (2010) Brain , vol.133 , pp. 3336-3348
    • Jack, Jr.C.R.1
  • 89
    • 32544435900 scopus 로고    scopus 로고
    • Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study
    • O. Hansson et al. Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study Lancet Neurol. 5 2006 228 234
    • (2006) Lancet Neurol. , vol.5 , pp. 228-234
    • Hansson, O.1
  • 90
    • 67649628753 scopus 로고    scopus 로고
    • Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study
    • P.J. Visser et al. Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study Lancet Neurol. 8 2009 619 627
    • (2009) Lancet Neurol. , vol.8 , pp. 619-627
    • Visser, P.J.1
  • 91
    • 0031283211 scopus 로고    scopus 로고
    • Lewy body dementia: clinical, pathological and neurochemical interconnections
    • R. Perry et al. Lewy body dementia: clinical, pathological and neurochemical interconnections J. Neural Transm. Suppl. 51 1997 95 109
    • (1997) J. Neural Transm. Suppl. , vol.51 , pp. 95-109
    • Perry, R.1
  • 92
    • 33845709899 scopus 로고    scopus 로고
    • Differences in neuropathologic characteristics across the Lewy body dementia spectrum
    • C. Ballard et al. Differences in neuropathologic characteristics across the Lewy body dementia spectrum Neurology 67 2006 1931 1934
    • (2006) Neurology , vol.67 , pp. 1931-1934
    • Ballard, C.1
  • 93
    • 56749185181 scopus 로고    scopus 로고
    • Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography
    • P. Edison et al. Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography J. Neurol. Neurosurg. Psychiatry 79 2008 1331 1338
    • (2008) J. Neurol. Neurosurg. Psychiatry , vol.79 , pp. 1331-1338
    • Edison, P.1
  • 94
    • 54049100454 scopus 로고    scopus 로고
    • Imaging amyloid deposition in Lewy body diseases
    • S.N. Gomperts et al. Imaging amyloid deposition in Lewy body diseases Neurology 71 2008 903 910
    • (2008) Neurology , vol.71 , pp. 903-910
    • Gomperts, S.N.1
  • 95
    • 47049100511 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers in Parkinson's disease with dementia and dementia with Lewy bodies
    • L. Parnetti et al. Cerebrospinal fluid biomarkers in Parkinson's disease with dementia and dementia with Lewy bodies Biol. Psychiatry 64 2008 850 855
    • (2008) Biol. Psychiatry , vol.64 , pp. 850-855
    • Parnetti, L.1
  • 96
    • 62149140954 scopus 로고    scopus 로고
    • Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics
    • W. Maetzler et al. Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics Neurobiol. Dis. 34 2009 107 112
    • (2009) Neurobiol. Dis. , vol.34 , pp. 107-112
    • Maetzler, W.1
  • 97
    • 84868585835 scopus 로고    scopus 로고
    • Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders
    • S. Hall et al. Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders Arch. Neurol. 69 2012 1445 1452
    • (2012) Arch. Neurol. , vol.69 , pp. 1445-1452
    • Hall, S.1
  • 98
    • 84874878881 scopus 로고    scopus 로고
    • Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease
    • M. Lehmann et al. Diverging patterns of amyloid deposition and hypometabolism in clinical variants of probable Alzheimer's disease Brain 136 2013 844 858
    • (2013) Brain , vol.136 , pp. 844-858
    • Lehmann, M.1
  • 99
    • 77954211308 scopus 로고    scopus 로고
    • CSF-tau and CSF-Abeta(1-42) in posterior cortical atrophy
    • T.P. Baumann et al. CSF-tau and CSF-Abeta(1-42) in posterior cortical atrophy Dement. Geriatr. Cogn. Disord. 29 2010 530 533
    • (2010) Dement. Geriatr. Cogn. Disord. , vol.29 , pp. 530-533
    • Baumann, T.P.1
  • 100
    • 79951801800 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers in the differential diagnosis of Alzheimer's disease from other cortical dementias
    • L.C. de Souza et al. Cerebrospinal fluid biomarkers in the differential diagnosis of Alzheimer's disease from other cortical dementias J. Neurol. Neurosurg. Psychiatry 82 2011 240 246
    • (2011) J. Neurol. Neurosurg. Psychiatry , vol.82 , pp. 240-246
    • De Souza, L.C.1
  • 101
    • 79958105092 scopus 로고    scopus 로고
    • CSF biomarkers in posterior cortical atrophy
    • J. Seguin et al. CSF biomarkers in posterior cortical atrophy Neurology 76 2011 1782 1788
    • (2011) Neurology , vol.76 , pp. 1782-1788
    • Seguin, J.1
  • 102
    • 0034646142 scopus 로고    scopus 로고
    • Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
    • M. Otto et al. Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease Neurology 54 2000 1099 1102
    • (2000) Neurology , vol.54 , pp. 1099-1102
    • Otto, M.1
  • 103
    • 0141852344 scopus 로고    scopus 로고
    • A prospective study of CSF markers in 250 patients with possible Creutzfeldt-Jakob disease
    • B. Van Everbroeck et al. A prospective study of CSF markers in 250 patients with possible Creutzfeldt-Jakob disease J. Neurol. Neurosurg. Psychiatry 74 2003 1210 1214
    • (2003) J. Neurol. Neurosurg. Psychiatry , vol.74 , pp. 1210-1214
    • Van Everbroeck, B.1
  • 104
    • 80053195298 scopus 로고    scopus 로고
    • Cerebrospinal fluid markers in sporadic Creutzfeldt-Jakob disease
    • G. Zanusso et al. Cerebrospinal fluid markers in sporadic Creutzfeldt-Jakob disease Int. J. Mol. Sci. 12 2011 6281 6292
    • (2011) Int. J. Mol. Sci. , vol.12 , pp. 6281-6292
    • Zanusso, G.1
  • 105
    • 84857047421 scopus 로고    scopus 로고
    • 11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease
    • H. Hyare et al. 11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease J. Neurol. Neurosurg. Psychiatry 83 2012 340 341
    • (2012) J. Neurol. Neurosurg. Psychiatry , vol.83 , pp. 340-341
    • Hyare, H.1
  • 106
    • 69449086022 scopus 로고    scopus 로고
    • 11C-PiB PET studies in typical sporadic Creutzfeldt-Jakob disease
    • V.L. Villemagne et al. 11C-PiB PET studies in typical sporadic Creutzfeldt-Jakob disease J. Neurol. Neurosurg. Psychiatry 80 2009 998 1001
    • (2009) J. Neurol. Neurosurg. Psychiatry , vol.80 , pp. 998-1001
    • Villemagne, V.L.1
  • 107
    • 84878860533 scopus 로고    scopus 로고
    • Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections
    • J.J. Krut et al. Cerebrospinal fluid Alzheimer's biomarker profiles in CNS infections J. Neurol. 260 2013 620 626
    • (2013) J. Neurol. , vol.260 , pp. 620-626
    • Krut, J.J.1
  • 108
    • 0035856397 scopus 로고    scopus 로고
    • Low cerebrospinal fluid beta-amyloid 42 in patients with acute bacterial meningitis and normalization after treatment
    • M. Sjogren et al. Low cerebrospinal fluid beta-amyloid 42 in patients with acute bacterial meningitis and normalization after treatment Neurosci. Lett. 314 2001 33 36
    • (2001) Neurosci. Lett. , vol.314 , pp. 33-36
    • Sjogren, M.1
  • 109
    • 77954657208 scopus 로고    scopus 로고
    • Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism
    • N. Mattsson et al. Neuroinflammation in Lyme neuroborreliosis affects amyloid metabolism BMC Neurol. 10 2010 51
    • (2010) BMC Neurol. , vol.10 , pp. 51
    • Mattsson, N.1
  • 110
    • 27644524501 scopus 로고    scopus 로고
    • CSF amyloid beta42 and tau levels correlate with AIDS dementia complex
    • B.J. Brew et al. CSF amyloid beta42 and tau levels correlate with AIDS dementia complex Neurology 65 2005 1490 1492
    • (2005) Neurology , vol.65 , pp. 1490-1492
    • Brew, B.J.1
  • 111
    • 4344586854 scopus 로고    scopus 로고
    • Decreased levels of soluble amyloid beta-protein precursor and beta-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus
    • E. Trysberg et al. Decreased levels of soluble amyloid beta-protein precursor and beta-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus Arthritis Res. Ther. 6 2004 R129 R136
    • (2004) Arthritis Res. Ther. , vol.6 , pp. R129-R136
    • Trysberg, E.1
  • 112
    • 63449105260 scopus 로고    scopus 로고
    • Reduced cerebrospinal fluid BACE1 activity in multiple sclerosis
    • N. Mattsson et al. Reduced cerebrospinal fluid BACE1 activity in multiple sclerosis Mult. Scler. 15 2009 448 454
    • (2009) Mult. Scler. , vol.15 , pp. 448-454
    • Mattsson, N.1
  • 113
    • 78651411152 scopus 로고    scopus 로고
    • Cognitive and cortical plasticity deficits correlate with altered amyloid-beta CSF levels in multiple sclerosis
    • F. Mori et al. Cognitive and cortical plasticity deficits correlate with altered amyloid-beta CSF levels in multiple sclerosis Neuropsychopharmacology 36 2011 559 568
    • (2011) Neuropsychopharmacology , vol.36 , pp. 559-568
    • Mori, F.1
  • 114
    • 84876552168 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarkers of beta-amyloid metabolism in multiple sclerosis
    • K. Augutis et al. Cerebrospinal fluid biomarkers of beta-amyloid metabolism in multiple sclerosis Mult. Scler. 19 2013 543 552
    • (2013) Mult. Scler. , vol.19 , pp. 543-552
    • Augutis, K.1
  • 115
    • 74549114139 scopus 로고    scopus 로고
    • Amyloid and tau cerebrospinal fluid biomarkers in HIV infection
    • M. Gisslen et al. Amyloid and tau cerebrospinal fluid biomarkers in HIV infection BMC Neurol. 9 2009 63
    • (2009) BMC Neurol. , vol.9 , pp. 63
    • Gisslen, M.1
  • 116
    • 84555206079 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of soluble amyloid precursor protein and beta-amyloid 42 in patients with multiple sclerosis, neuromyelitis optica and clinically isolated syndrome
    • W. Mai et al. Cerebrospinal fluid levels of soluble amyloid precursor protein and beta-amyloid 42 in patients with multiple sclerosis, neuromyelitis optica and clinically isolated syndrome J. Int. Med. Res. 39 2011 2402 2413
    • (2011) J. Int. Med. Res. , vol.39 , pp. 2402-2413
    • Mai, W.1
  • 117
    • 84882453644 scopus 로고    scopus 로고
    • Evaluating biomarkers of neuronal degeneration and neuroinflammation in CSF of patients with multiple sclerosis-osteopontin as a potential marker of clinical severity
    • L. Szalardy et al. Evaluating biomarkers of neuronal degeneration and neuroinflammation in CSF of patients with multiple sclerosis-osteopontin as a potential marker of clinical severity J. Neurol. Sci. 331 2013 38 42
    • (2013) J. Neurol. Sci. , vol.331 , pp. 38-42
    • Szalardy, L.1
  • 118
    • 84877285804 scopus 로고    scopus 로고
    • Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers
    • S.T. DeKosky et al. Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers Nat. Rev. Neurol. 9 2013 192 200
    • (2013) Nat. Rev. Neurol. , vol.9 , pp. 192-200
    • DeKosky, S.T.1
  • 119
    • 79961158069 scopus 로고    scopus 로고
    • Traumatic brain injury and amyloid-beta pathology: a link to Alzheimer's disease?
    • V.E. Johnson et al. Traumatic brain injury and amyloid-beta pathology: a link to Alzheimer's disease? Nat. Rev. Neurosci. 11 2010 361 370
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 361-370
    • Johnson, V.E.1
  • 120
    • 0028987679 scopus 로고
    • Distribution of beta-amyloid protein in the brain following severe head injury
    • D.I. Graham et al. Distribution of beta-amyloid protein in the brain following severe head injury Neuropathol. Appl. Neurobiol. 21 1995 27 34
    • (1995) Neuropathol. Appl. Neurobiol. , vol.21 , pp. 27-34
    • Graham, D.I.1
  • 121
    • 0025840201 scopus 로고
    • beta A4 amyloid protein deposition in brain after head trauma
    • G.W. Roberts et al. beta A4 amyloid protein deposition in brain after head trauma Lancet 338 1991 1422 1423
    • (1991) Lancet , vol.338 , pp. 1422-1423
    • Roberts, G.W.1
  • 122
    • 0037404532 scopus 로고    scopus 로고
    • Amyloid beta accumulation in axons after traumatic brain injury in humans
    • D.H. Smith et al. Amyloid beta accumulation in axons after traumatic brain injury in humans J. Neurosurg. 98 2003 1072 1077
    • (2003) J. Neurosurg. , vol.98 , pp. 1072-1077
    • Smith, D.H.1
  • 123
    • 5044237263 scopus 로고    scopus 로고
    • Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury
    • M.D. Ikonomovic et al. Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury Exp. Neurol. 190 2004 192 203
    • (2004) Exp. Neurol. , vol.190 , pp. 192-203
    • Ikonomovic, M.D.1
  • 124
    • 84892425262 scopus 로고    scopus 로고
    • Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury
    • Y.T. Hong et al. Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury JAMA Neurol. 71 2014 23 31
    • (2014) JAMA Neurol. , vol.71 , pp. 23-31
    • Hong, Y.T.1
  • 125
    • 3442881114 scopus 로고    scopus 로고
    • Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury
    • A. Olsson et al. Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury J. Neurol. 251 2004 870 876
    • (2004) J. Neurol. , vol.251 , pp. 870-876
    • Olsson, A.1
  • 126
    • 84900988440 scopus 로고    scopus 로고
    • Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
    • B. Dubois et al. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria Lancet Neurol. 13 2014 614 629
    • (2014) Lancet Neurol. , vol.13 , pp. 614-629
    • Dubois, B.1
  • 127
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • G.M. McKhann et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement. 7 2011 263 269
    • (2011) Alzheimers Dement. , vol.7 , pp. 263-269
    • McKhann, G.M.1
  • 128
    • 79956084514 scopus 로고    scopus 로고
    • The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • M.S. Albert et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement. 7 2011 270 279
    • (2011) Alzheimers Dement. , vol.7 , pp. 270-279
    • Albert, M.S.1
  • 129
    • 84907155863 scopus 로고    scopus 로고
    • Cost-effectiveness of the use of biomarkers in cerebrospinal fluid for Alzheimer's disease
    • C. Valcarcel-Nazco et al. Cost-effectiveness of the use of biomarkers in cerebrospinal fluid for Alzheimer's disease J. Alzheimers Dis. 42 2014 777 788
    • (2014) J. Alzheimers Dis. , vol.42 , pp. 777-788
    • Valcarcel-Nazco, C.1
  • 130
    • 0027373325 scopus 로고
    • Low frequency of post-lumbar puncture headache in demented patients
    • K. Blennow et al. Low frequency of post-lumbar puncture headache in demented patients Acta Neurol. Scand. 88 1993 221 223
    • (1993) Acta Neurol. Scand. , vol.88 , pp. 221-223
    • Blennow, K.1
  • 131
    • 67149098346 scopus 로고    scopus 로고
    • Safety of lumbar puncture procedures in patients with Alzheimer's disease
    • E. Peskind et al. Safety of lumbar puncture procedures in patients with Alzheimer's disease Curr. Alzheimer Res. 6 2009 290 292
    • (2009) Curr. Alzheimer Res. , vol.6 , pp. 290-292
    • Peskind, E.1
  • 132
    • 33644982566 scopus 로고    scopus 로고
    • Safety and acceptability of the research lumbar puncture
    • E.R. Peskind et al. Safety and acceptability of the research lumbar puncture Alzheimer Dis. Assoc. Disord. 19 2005 220 225
    • (2005) Alzheimer Dis. Assoc. Disord. , vol.19 , pp. 220-225
    • Peskind, E.R.1
  • 133
    • 77952870556 scopus 로고    scopus 로고
    • Low incidence of post-lumbar puncture headache in 1,089 consecutive memory clinic patients
    • H. Zetterberg et al. Low incidence of post-lumbar puncture headache in 1,089 consecutive memory clinic patients Eur. Neurol. 63 2010 326 330
    • (2010) Eur. Neurol. , vol.63 , pp. 326-330
    • Zetterberg, H.1
  • 134
    • 84896882468 scopus 로고    scopus 로고
    • Feasibility of lumbar puncture in the study of cerebrospinal fluid biomarkers for Alzheimer's disease: a multicenter study in Spain
    • D. Alcolea et al. Feasibility of lumbar puncture in the study of cerebrospinal fluid biomarkers for Alzheimer's disease: a multicenter study in Spain J. Alzheimers Dis. 39 2014 719 726
    • (2014) J. Alzheimers Dis. , vol.39 , pp. 719-726
    • Alcolea, D.1
  • 135
    • 72049130805 scopus 로고    scopus 로고
    • Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
    • C.R. Jack Jr et al. Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade Lancet Neurol. 9 2010 119 128
    • (2010) Lancet Neurol. , vol.9 , pp. 119-128
    • Jack, Jr.C.R.1
  • 136
    • 84872379077 scopus 로고    scopus 로고
    • Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
    • C.R. Jack Jr et al. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers Lancet Neurol. 12 2013 207 216
    • (2013) Lancet Neurol. , vol.12 , pp. 207-216
    • Jack, Jr.C.R.1
  • 137
    • 84865529158 scopus 로고    scopus 로고
    • Clinical and biomarker changes in dominantly inherited Alzheimer's disease
    • R.J. Bateman et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease N. Engl. J. Med. 367 2012 795 804
    • (2012) N. Engl. J. Med. , vol.367 , pp. 795-804
    • Bateman, R.J.1
  • 138
    • 84929319498 scopus 로고    scopus 로고
    • Developments in Tau PET Imaging
    • E.R. Zimmer et al. Developments in Tau PET Imaging Can. J. Neurol. Sci. 41 2014 547 553
    • (2014) Can. J. Neurol. Sci. , vol.41 , pp. 547-553
    • Zimmer, E.R.1
  • 139
    • 84990967378 scopus 로고    scopus 로고
    • SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease
    • A. Brinkmalm et al. SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease Mol. Neurodegener. 9 2014 53
    • (2014) Mol. Neurodegener. , vol.9 , pp. 53
    • Brinkmalm, A.1
  • 140
    • 84945471565 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease
    • Published December 19, 2014
    • H. Kvartsberg et al. Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease Alzheimers Dement. 2014 10.1016/j.jalz.2014.10.009 Published December 19, 2014
    • (2014) Alzheimers Dement.
    • Kvartsberg, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.