메뉴 건너뛰기




Volumn 71, Issue 6, 2016, Pages 1510-1519

Inactivation or inhibition of AcrAB-TolC increases resistance of carbapenemase-producing Enterobacteriaceae to carbapenems

Author keywords

[No Author keywords available]

Indexed keywords

ACRAB PROTEIN; BACTERIAL PROTEIN; CARBAPENEM; CARBAPENEMASE; ERTAPENEM; OUTER MEMBRANE PROTEIN; PORIN; TOLC PROTEIN; UNCLASSIFIED DRUG; ACRAB-TOLC PROTEIN, E COLI; ACRAB-TOLC PROTEIN, SALMONELLA ENTERICA; ANTIINFECTIVE AGENT; BETA LACTAMASE; CARBAPENEM DERIVATIVE; CARRIER PROTEIN; ENZYME INHIBITOR; ESCHERICHIA COLI PROTEIN; MULTIDRUG RESISTANCE PROTEIN;

EID: 84973301097     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkw028     Document Type: Article
Times cited : (38)

References (47)
  • 2
    • 84857195282 scopus 로고    scopus 로고
    • The crisis of no new antibiotics-what is the way forward?
    • Piddock LJV. The crisis of no new antibiotics-what is the way forward? Lancet Infect Dis 2012; 12: 249-53.
    • (2012) Lancet Infect Dis , vol.12 , pp. 249-253
    • Piddock, L.J.V.1
  • 4
    • 84926153992 scopus 로고    scopus 로고
    • Carbapenemase-producing Gram-negative bacteria: current epidemics, antimicrobial susceptibility and treatment options
    • Jean SS, Lee WS, LamC et al. Carbapenemase-producing Gram-negative bacteria: current epidemics, antimicrobial susceptibility and treatment options. Future Microbiol 2015; 10: 407-25.
    • (2015) Future Microbiol , vol.10 , pp. 407-425
    • Jean, S.S.1    Lee, W.S.2    Lam, C.3
  • 5
    • 84896724608 scopus 로고    scopus 로고
    • Carbapenemase-producing Enterobacteriaceae: overview of a major public health challenge
    • Nordmann P. Carbapenemase-producing Enterobacteriaceae: overview of a major public health challenge. Med Mal Infect 2014; 44: 51-6.
    • (2014) Med Mal Infect , vol.44 , pp. 51-56
    • Nordmann, P.1
  • 6
    • 21444442707 scopus 로고    scopus 로고
    • Emergence of KPC-possessing Klebsiella pneumoniae in Brooklyn, New York: epidemiology and recommendations for detection.
    • Bratu S, Mooty M, Nichani S et al. Emergence of KPC-possessing Klebsiella pneumoniae in Brooklyn, New York: epidemiology and recommendations for detection. Antimicrob Agents Chemother 2005; 49:3018-20.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3018-3020
    • Bratu, S.1    Mooty, M.2    Nichani, S.3
  • 7
    • 80355126233 scopus 로고    scopus 로고
    • Accuracy of carbapenem nonsusceptibility for identification of KPC-possessing Enterobacteriaceae by use of the revised CLSI breakpoints
    • Landman D, Salamera J, SinghM et al. Accuracy of carbapenem nonsusceptibility for identification of KPC-possessing Enterobacteriaceae by use of the revised CLSI breakpoints. J Clin Microbiol 2011; 49: 3931-3.
    • (2011) J Clin Microbiol , vol.49 , pp. 3931-3933
    • Landman, D.1    Salamera, J.2    Singh, M.3
  • 8
    • 78650056189 scopus 로고    scopus 로고
    • Susceptibility profiles, molecular epidemiology, and detection of KPC-producing Escherichia coli isolates from the New York City vicinity
    • Landman D, Urban C, Bäcker M et al. Susceptibility profiles, molecular epidemiology, and detection of KPC-producing Escherichia coli isolates from the New York City vicinity. J Clin Microbiol 2010; 48: 4604-7.
    • (2010) J Clin Microbiol , vol.48 , pp. 4604-4607
    • Landman, D.1    Urban, C.2    Bäcker, M.3
  • 9
    • 77957338681 scopus 로고    scopus 로고
    • Genetic factors associated with elevated carbapenem resistance in KPC-producing Klebsiella pneumoniae
    • Kitchel B, Rasheed JK, Endimiani A et al. Genetic factors associated with elevated carbapenem resistance in KPC-producing Klebsiella pneumoniae. Antimicrob Agents Chemother 2010; 54: 4201-7.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4201-4207
    • Kitchel, B.1    Rasheed, J.K.2    Endimiani, A.3
  • 10
    • 79953222226 scopus 로고    scopus 로고
    • Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence
    • Tsai YK, Fung CP, Lin JC et al. Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence. Antimicrob Agents Chemother 2011; 55: 1485-93.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1485-1493
    • Tsai, Y.K.1    Fung, C.P.2    Lin, J.C.3
  • 11
    • 70349312522 scopus 로고    scopus 로고
    • Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae
    • Landman D, Bratu S, Quale J. Contribution of OmpK36 to carbapenem susceptibility in KPC-producing Klebsiella pneumoniae. J Med Microbiol 2009; 58: 1303-8.
    • (2009) J Med Microbiol , vol.58 , pp. 1303-1308
    • Landman, D.1    Bratu, S.2    Quale, J.3
  • 12
    • 33646251815 scopus 로고    scopus 로고
    • Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria
    • Piddock LJV. Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin Microbiol Rev 2006; 19: 382-402.
    • (2006) Clin Microbiol Rev , vol.19 , pp. 382-402
    • Piddock, L.J.V.1
  • 13
    • 62849121696 scopus 로고    scopus 로고
    • Efflux pump, the masked side of ß-lactam resistance in Klebsiella pneumoniae clinical isolates
    • Pages J-M, Lavigne J-P, Leflon-Guibout Vet al. Efflux pump, the masked side of ß-lactam resistance in Klebsiella pneumoniae clinical isolates. PLoS One 2009; 4: e4817.
    • (2009) PLoS One , vol.4 , pp. e4817
    • Pages, J.-M.1    Lavigne, J.-P.2    Leflon-Guibout, V.3
  • 14
    • 84893517787 scopus 로고    scopus 로고
    • Characterization of a novel pyranopyridine inhibitor of the AcrAB efflux pump of Escherichia coli
    • Opperman TJ, Kwasny SM, Kim HS et al. Characterization of a novel pyranopyridine inhibitor of the AcrAB efflux pump of Escherichia coli. Antimicrob Agents Chemother 2014; 58: 722-33.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 722-733
    • Opperman, T.J.1    Kwasny, S.M.2    Kim, H.S.3
  • 15
    • 0032529948 scopus 로고    scopus 로고
    • Overexpression of marA, soxS, or acrAB produces resistance to triclosan in laboratory and clinical strains of Escherichia coli
    • McMurry LM, Oethinger M, Levy SB. Overexpression of marA, soxS, or acrAB produces resistance to triclosan in laboratory and clinical strains of Escherichia coli. FEMS Microbiol Lett 1998; 166: 305-9.
    • (1998) FEMS Microbiol Lett , vol.166 , pp. 305-309
    • McMurry, L.M.1    Oethinger, M.2    Levy, S.B.3
  • 16
    • 0033989647 scopus 로고    scopus 로고
    • Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump
    • Oethinger M, Kern WV, Jellen-Ritter AS et al. Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump. Antimicrob Agents Chemother 2000; 44: 10-3.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 10-13
    • Oethinger, M.1    Kern, W.V.2    Jellen-Ritter, A.S.3
  • 17
    • 29944433409 scopus 로고    scopus 로고
    • Ciprofloxacin-resistant Salmonella enterica serovar Typhimurium strains are difficult to select in the absence of AcrB and TolC
    • Ricci V, Tzakas P, Buckley A et al. Ciprofloxacin-resistant Salmonella enterica serovar Typhimurium strains are difficult to select in the absence of AcrB and TolC. Antimicrob Agents Chemother 2006; 50: 38-42.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 38-42
    • Ricci, V.1    Tzakas, P.2    Buckley, A.3
  • 18
    • 0034612342 scopus 로고    scopus 로고
    • One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products.
    • Datsenko KA,Wanner BL. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci USA 2000; 97:6640-5.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6640-6645
    • Datsenko, K.A.1    Wanner, B.L.2
  • 19
    • 84904017979 scopus 로고    scopus 로고
    • Functional genomics to identify the factors contributing to successful persistence and global spread of an antibiotic resistance plasmid
    • Cottell JL, Saw HTH, Webber MA et al. Functional genomics to identify the factors contributing to successful persistence and global spread of an antibiotic resistance plasmid. BMC Microbiol 2014; 14: 168.
    • (2014) BMC Microbiol , vol.14 , pp. 168
    • Cottell, J.L.1    Saw, H.T.H.2    Webber, M.A.3
  • 20
    • 0034924241 scopus 로고    scopus 로고
    • Determination of minimum inhibitory concentrations
    • Andrews JM. Determination of minimum inhibitory concentrations. J Antimicrob Chemother 2001; 48 Suppl 1: 5-16.
    • (2001) J Antimicrob Chemother , vol.48 , pp. 5-16
    • Andrews, J.M.1
  • 21
    • 0025695543 scopus 로고
    • A comparison of the mechanisms of decreased susceptibility of aztreonam-resistant and ceftazidime-resistant Enterobacteriaceae
    • Piddock LJV, Traynor EA, Wise R. A comparison of the mechanisms of decreased susceptibility of aztreonam-resistant and ceftazidime-resistant Enterobacteriaceae. J Antimicrob Chemother 1990; 26: 749-62.
    • (1990) J Antimicrob Chemother , vol.26 , pp. 749-762
    • Piddock, L.J.V.1    Traynor, E.A.2    Wise, R.3
  • 22
    • 62549121211 scopus 로고    scopus 로고
    • Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK
    • Doumith M, Ellington MJ, Livermore DM et al. Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK. J Antimicrob Chemother 2009; 63: 659-67.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 659-667
    • Doumith, M.1    Ellington, M.J.2    Livermore, D.M.3
  • 23
    • 84902438273 scopus 로고    scopus 로고
    • NDM carbapenemases in the United Kingdom: an analysis of the first 250 cases
    • Jain A, Hopkins KL, Turton J et al. NDM carbapenemases in the United Kingdom: an analysis of the first 250 cases. J Antimicrob Chemother 2014; 69: 1777-84.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 1777-1784
    • Jain, A.1    Hopkins, K.L.2    Turton, J.3
  • 24
    • 77954437585 scopus 로고    scopus 로고
    • Characteristics of meropenem heteroresistance in Klebsiella pneumoniae carbapenemase (KPC)-producing clinical isolates of K. pneumoniae
    • Pournaras S, Kristo I, Vrioni G et al. Characteristics of meropenem heteroresistance in Klebsiella pneumoniae carbapenemase (KPC)-producing clinical isolates of K. pneumoniae. J Clin Microbiol 2010; 48: 2601-4.
    • (2010) J Clin Microbiol , vol.48 , pp. 2601-2604
    • Pournaras, S.1    Kristo, I.2    Vrioni, G.3
  • 25
    • 84899858005 scopus 로고    scopus 로고
    • Heteroresistance to carbapenems in NewDelhi metallo-b-lactamase-1-producing isolates: a challenge for detection?
    • Zavascki AP, Falci DR, Da Silva RCF et al. Heteroresistance to carbapenems in NewDelhi metallo-b-lactamase-1-producing isolates: a challenge for detection? Infect Control Hosp Epidemiol 2014; 35: 751-2.
    • (2014) Infect Control Hosp Epidemiol , vol.35 , pp. 751-752
    • Zavascki, A.P.1    Falci, D.R.2    Da Silva, R.C.F.3
  • 26
    • 84871652077 scopus 로고    scopus 로고
    • Underlying mechanisms of carbapenem resistance in extended-spectrum b-lactamase-producing Klebsiella pneumoniae and Escherichia coli isolates at a tertiary care centre in Lebanon: role of OXA-48 and NDM-1 carbapenemases
    • Baroud M, Dandache I, Araj GF et al. Underlying mechanisms of carbapenem resistance in extended-spectrum b-lactamase-producing Klebsiella pneumoniae and Escherichia coli isolates at a tertiary care centre in Lebanon: role of OXA-48 and NDM-1 carbapenemases. Int J Antimicrob Agents 2013; 41: 75-9.
    • (2013) Int J Antimicrob Agents , vol.41 , pp. 75-79
    • Baroud, M.1    Dandache, I.2    Araj, G.F.3
  • 27
    • 33746928431 scopus 로고    scopus 로고
    • Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in Enterobacter cloacae
    • Szabó D, Silveira F, Hujer AM et al. Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in Enterobacter cloacae. Antimicrob Agents Chemother 2006; 50: 2833-5.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2833-2835
    • Szabó, D.1    Silveira, F.2    Hujer, A.M.3
  • 28
    • 84862908913 scopus 로고    scopus 로고
    • Characterization of ertapenem-resistant Enterobacter cloacae in a Taiwanese University Hospital
    • Yang FC, Yan JJ, Hung KH et al. Characterization of ertapenem-resistant Enterobacter cloacae in a Taiwanese University Hospital. J Clin Microbiol 2012; 50: 223-6.
    • (2012) J Clin Microbiol , vol.50 , pp. 223-226
    • Yang, F.C.1    Yan, J.J.2    Hung, K.H.3
  • 29
    • 84888246858 scopus 로고    scopus 로고
    • Some ligands enhance the efflux of other ligands by the Escherichia coli multidrug pump AcrB
    • Kinana AD, Vargiu AV, Nikaido H. Some ligands enhance the efflux of other ligands by the Escherichia coli multidrug pump AcrB. Biochemistry 2013; 52: 8342-51.
    • (2013) Biochemistry , vol.52 , pp. 8342-8351
    • Kinana, A.D.1    Vargiu, A.V.2    Nikaido, H.3
  • 30
    • 84875478948 scopus 로고    scopus 로고
    • The efflux inhibitor phenylalaninearginine b-naphthylamide (PAbN) permeabilizes the outer membrane of Gram-negative bacteria
    • Lamers RP, Cavallari JF, Burrows LL. The efflux inhibitor phenylalaninearginine b-naphthylamide (PAbN) permeabilizes the outer membrane of Gram-negative bacteria. PLoS One 2013; 8: e60666.
    • (2013) PLoS One , vol.8 , pp. e60666
    • Lamers, R.P.1    Cavallari, J.F.2    Burrows, L.L.3
  • 31
    • 79954553031 scopus 로고    scopus 로고
    • Evaluation of multidrug efflux pump inhibitors by a new method using microfluidic channels
    • Matsumoto Y, Hayama K, Sakakihara S et al. Evaluation of multidrug efflux pump inhibitors by a new method using microfluidic channels. PLoS One 2011; 6: e18547.
    • (2011) PLoS One , vol.6 , pp. e18547
    • Matsumoto, Y.1    Hayama, K.2    Sakakihara, S.3
  • 32
    • 0034119459 scopus 로고    scopus 로고
    • Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA
    • Barbosa TM, Levy SB. Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA. J Bacteriol 2000; 182: 3467-74.
    • (2000) J Bacteriol , vol.182 , pp. 3467-3474
    • Barbosa, T.M.1    Levy, S.B.2
  • 33
    • 84875143305 scopus 로고    scopus 로고
    • Elucidating the regulon of multidrug resistance regulator rarA in Klebsiella pneumoniae
    • De Majumdar S, Veleba M, Finn S et al. Elucidating the regulon of multidrug resistance regulator rarA in Klebsiella pneumoniae. Antimicrob Agents Chemother 2013; 57: 1603-9.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1603-1609
    • De Majumdar, S.1    Veleba, M.2    Finn, S.3
  • 34
    • 67649414443 scopus 로고    scopus 로고
    • The global consequence of disruption of the AcrAB-TolC efflux pump in Salmonella enterica includes reduced expression of SPI-1 and other attributes required to infect the host
    • Webber MA, Bailey AM, Blair JMA et al. The global consequence of disruption of the AcrAB-TolC efflux pump in Salmonella enterica includes reduced expression of SPI-1 and other attributes required to infect the host. J Bacteriol 2009; 191: 4276-85.
    • (2009) J Bacteriol , vol.191 , pp. 4276-4285
    • Webber, M.A.1    Bailey, A.M.2    Blair, J.M.A.3
  • 36
    • 0345434969 scopus 로고    scopus 로고
    • The ompB operon partially determines differential expression of OmpC in Salmonella typhi and Escherichia coli
    • Martínez-Flores I, Cano R, Bustamante VH et al. The ompB operon partially determines differential expression of OmpC in Salmonella typhi and Escherichia coli. J Bacteriol 1999; 181: 556-62.
    • (1999) J Bacteriol , vol.181 , pp. 556-562
    • Martínez-Flores, I.1    Cano, R.2    Bustamante, V.H.3
  • 37
    • 64649103209 scopus 로고    scopus 로고
    • Mechanisms of drug efflux and strategies to combat them: challenging the efflux pump of Gram-negative bacteria
    • Pagès J-M, Amaral L. Mechanisms of drug efflux and strategies to combat them: challenging the efflux pump of Gram-negative bacteria. Biochim Biophys Acta 2009; 1794: 826-33.
    • (2009) Biochim Biophys Acta , vol.1794 , pp. 826-833
    • Pagès, J.-M.1    Amaral, L.2
  • 38
    • 79952838766 scopus 로고    scopus 로고
    • Complete sequencing of pNDM-HK encoding NDM-1 carbapenemase from a multidrug-resistant Escherichia coli strain isolated in Hong Kong.
    • Ho PL, Lo WU, Yeung MK et al. Complete sequencing of pNDM-HK encoding NDM-1 carbapenemase from a multidrug-resistant Escherichia coli strain isolated in Hong Kong. PLoS One 2011; 6:e17989.
    • (2011) PLoS One , vol.6 , pp. e17989
    • Ho, P.L.1    Lo, W.U.2    Yeung, M.K.3
  • 39
    • 14044278346 scopus 로고    scopus 로고
    • Extended-spectrum b-lactamase detected in E. coli recovered from calves in Wales
    • Teale CJ, Barker L, Foster AP et al. Extended-spectrum b-lactamase detected in E. coli recovered from calves in Wales. Vet Rec 2005; 156: 186-7.
    • (2005) Vet Rec , vol.156 , pp. 186-187
    • Teale, C.J.1    Barker, L.2    Foster, A.P.3
  • 40
    • 0021073779 scopus 로고
    • Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis
    • Norrander J, Kempe T, Messing J. Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis. Gene 1983; 26: 101-6.
    • (1983) Gene , vol.26 , pp. 101-106
    • Norrander, J.1    Kempe, T.2    Messing, J.3
  • 41
    • 0020463437 scopus 로고
    • dha System mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418
    • Forage RG, Lin ECC. dha System mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418. J Bacteriol 1982; 151: 591-9.
    • (1982) J Bacteriol , vol.151 , pp. 591-599
    • Forage, R.G.1    Lin, E.C.C.2
  • 42
    • 84864388734 scopus 로고    scopus 로고
    • Characterization of RarA, a novel AraC family multidrug resistance regulator in Klebsiella pneumoniae
    • Veleba M, Higgins PG, Gonzalez G et al. Characterization of RarA, a novel AraC family multidrug resistance regulator in Klebsiella pneumoniae. Antimicrob Agents Chemother 2012; 56: 4450-8.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4450-4458
    • Veleba, M.1    Higgins, P.G.2    Gonzalez, G.3
  • 43
    • 31544450286 scopus 로고    scopus 로고
    • Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection
    • Baba T, Ara T, Hasegawa M et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2006; 2.
    • (2006) Mol Syst Biol , pp. 2
    • Baba, T.1    Ara, T.2    Hasegawa, M.3
  • 44
    • 33645062695 scopus 로고    scopus 로고
    • Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium
    • Nishino K, Latifi T, Groisman EA. Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium. Mol Microbiol 2006; 59: 126-41.
    • (2006) Mol Microbiol , vol.59 , pp. 126-141
    • Nishino, K.1    Latifi, T.2    Groisman, E.A.3
  • 45
    • 0018015813 scopus 로고
    • Experimental Salmonella Typhimurium infection in calves
    • Wray C, Sojka WJ. Experimental Salmonella Typhimurium infection in calves. Res Vet Sci 1978; 25: 139-43.
    • (1978) Res Vet Sci , vol.25 , pp. 139-143
    • Wray, C.1    Sojka, W.J.2
  • 46
    • 73949100424 scopus 로고    scopus 로고
    • Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium
    • Blair JM, La Ragione RM, Woodward MJ et al. Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium. J Antimicrob Chemother 2009; 64: 965-72.
    • (2009) J Antimicrob Chemother , vol.64 , pp. 965-972
    • Blair, J.M.1    La Ragione, R.M.2    Woodward, M.J.3
  • 47
    • 33645548647 scopus 로고    scopus 로고
    • The AcrAB-TolC efflux system of Salmonella enterica serovar Typhimuriumplays a role in pathogenesis
    • Buckley AM,Webber MA, Cooles S et al. The AcrAB-TolC efflux system of Salmonella enterica serovar Typhimuriumplays a role in pathogenesis. Cell Microbiol 2006; 8: 847-56.
    • (2006) Cell Microbiol , vol.8 , pp. 847-856
    • Buckley, A.M.1    Webber, M.A.2    Cooles, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.