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Volumn 6, Issue , 2016, Pages

Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; IL10 PROTEIN, MOUSE; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; STAT1 PROTEIN; STAT1 PROTEIN, MOUSE; TLR3 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 3;

EID: 84973294728     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep26851     Document Type: Article
Times cited : (71)

References (55)
  • 1
    • 84878495699 scopus 로고    scopus 로고
    • Advances in research on animal models of rheumatoid arthritis
    • Hu, Y. et al. Advances in research on animal models of rheumatoid arthritis. Clin Rheumatol 32, 161-165, doi: 10.1007/s10067-012-2041-1 (2013).
    • (2013) Clin Rheumatol , vol.32 , pp. 161-165
    • Hu, Y.1
  • 2
    • 84893605539 scopus 로고    scopus 로고
    • Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis
    • Benedetti, G. & Miossec, P. Interleukin 17 contributes to the chronicity of inflammatory diseases such as rheumatoid arthritis. Eur J Immunol 44, 339-347, doi: 10.1002/eji.201344184 (2014).
    • (2014) Eur J Immunol , vol.44 , pp. 339-347
    • Benedetti, G.1    Miossec, P.2
  • 3
    • 84896542936 scopus 로고    scopus 로고
    • Th17 and regulatory T cell balance in autoimmune and inflammatory diseases
    • Noack, M. & Miossec, P. Th17 and regulatory T cell balance in autoimmune and inflammatory diseases. Autoimmun Rev 13, 668-677, doi: 10.1016/j.autrev.2013.12.004 (2014).
    • (2014) Autoimmun Rev , vol.13 , pp. 668-677
    • Noack, M.1    Miossec, P.2
  • 4
    • 84925713730 scopus 로고    scopus 로고
    • Gastrointestinal events in at-risk patients starting non-steroidal anti-inflammatory drugs (NSAIDs) for rheumatic diseases: The EVIDENCE study of European routine practice
    • Lanas, A., Boers, M. & Nuevo, J. Gastrointestinal events in at-risk patients starting non-steroidal anti-inflammatory drugs (NSAIDs) for rheumatic diseases: the EVIDENCE study of European routine practice. Ann Rheum Dis, doi: 10.1136/annrheumdis-2013-204155 (2013).
    • (2013) Ann Rheum Dis
    • Lanas, A.1    Boers, M.2    Nuevo, J.3
  • 5
    • 84860802208 scopus 로고    scopus 로고
    • Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis)
    • Colebatch, A. N., Marks, J. L. & Edwards, C. J. Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis). Cochrane Database Syst Rev, CD008872, doi: 10.1002/14651858.CD008872.pub2 (2011).
    • (2011) Cochrane Database Syst Rev , pp. CD008872
    • Colebatch, A.N.1    Marks, J.L.2    Edwards, C.J.3
  • 6
    • 4944228042 scopus 로고    scopus 로고
    • Glucocorticoid use in rheumatoid arthritis: Benefits, mechanisms, and risks
    • Townsend, H. B. & Saag, K. G. Glucocorticoid use in rheumatoid arthritis: benefits, mechanisms, and risks. Clin Exp Rheumatol 22, S77-82 (2004).
    • (2004) Clin Exp Rheumatol , vol.22 , pp. S77-S82
    • Townsend, H.B.1    Saag, K.G.2
  • 7
    • 84893721202 scopus 로고    scopus 로고
    • Efficacy of biological disease-modifying antirheumatic drugs: A systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis
    • Nam, J. L. et al. Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis 73, 516-528, doi: 10.1136/annrheumdis-2013-204577 (2014).
    • (2014) Ann Rheum Dis , vol.73 , pp. 516-528
    • Nam, J.L.1
  • 8
    • 84857711981 scopus 로고    scopus 로고
    • Toxicity of non-steroidal anti-inflammatory drugs: A review of melatonin and diclofenac sodium association
    • Aygun, D., Kaplan, S., Odaci, E., Onger, M. E. & Altunkaynak, M. E. Toxicity of non-steroidal anti-inflammatory drugs: a review of melatonin and diclofenac sodium association. Histo Histopathol 27, 417-436 (2012).
    • (2012) Histo Histopathol , vol.27 , pp. 417-436
    • Aygun, D.1    Kaplan, S.2    Odaci, E.3    Onger, M.E.4    Altunkaynak, M.E.5
  • 9
    • 77958467862 scopus 로고    scopus 로고
    • Immunosuppression by mesenchymal stem cells: Mechanisms and clinical applications
    • Ghannam, S., Bouffi, C., Djouad, F., Jorgensen, C. & Noel, D. Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications. Stem Cell Res Ther 1, 2, doi: 10.1186/scrt2 (2010).
    • (2010) Stem Cell Res Ther , vol.1 , pp. 2
    • Ghannam, S.1    Bouffi, C.2    Djouad, F.3    Jorgensen, C.4    Noel, D.5
  • 10
    • 84880396453 scopus 로고    scopus 로고
    • Clinical applications of mesenchymal stem cells
    • Kim, N. & Cho, S. G. Clinical applications of mesenchymal stem cells. Korean J Intern Med 28, 387-402, doi: 10.3904/kjim.2013.28.4.387 (2013).
    • (2013) Korean J Intern Med , vol.28 , pp. 387-402
    • Kim, N.1    Cho, S.G.2
  • 11
    • 84883898505 scopus 로고    scopus 로고
    • Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: Experiments and practice
    • Kim, N. et al. Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: experiments and practice. Ann Hematol 92, 1295-1308, doi: 10.1007/s00277-013-1796-z (2013).
    • (2013) Ann Hematol , vol.92 , pp. 1295-1308
    • Kim, N.1
  • 12
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study
    • Le Blanc, K. et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet 371, 1579-1586, doi: 10.1016/S0140-6736(08)60690-X (2008).
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1
  • 13
    • 84874246720 scopus 로고    scopus 로고
    • Toll-like receptors as modulators of mesenchymal stem cells
    • Delarosa, O., Dalemans, W. & Lombardo, E. Toll-like receptors as modulators of mesenchymal stem cells. Front Immunol 3, 182, doi: 10.3389/fimmu.2012.00182 (2012).
    • (2012) Front Immunol , vol.3 , pp. 182
    • Delarosa, O.1    Dalemans, W.2    Lombardo, E.3
  • 14
    • 77956420421 scopus 로고    scopus 로고
    • A new mesenchymal stem cell (MSC) paradigm: Polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype
    • Waterman, R. S., Tomchuck, S. L., Henkle, S. L. & Betancourt, A. M. A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype. PLos One 5, e10088, doi: 10.1371/journal. pone.0010088 (2010).
    • (2010) PLos One , vol.5 , pp. e10088
    • Waterman, R.S.1    Tomchuck, S.L.2    Henkle, S.L.3    Betancourt, A.M.4
  • 15
    • 77949261589 scopus 로고    scopus 로고
    • Immunosuppressive effects of mesenchymal stem cells in collagen-induced mouse arthritis
    • Mao, F. et al. Immunosuppressive effects of mesenchymal stem cells in collagen-induced mouse arthritis. Inflamm Res 59, 219-225, doi: 10.1007/s00011-009-0090-y (2010).
    • (2010) Inflamm Res , vol.59 , pp. 219-225
    • Mao, F.1
  • 16
    • 33750061010 scopus 로고    scopus 로고
    • Remission of collagen-induced arthritis is associated with high levels of transforming growth factor-beta expression in the joint
    • Marinova-Mutafchieva, L., Gabay, C., Funa, K. & Williams, R. O. Remission of collagen-induced arthritis is associated with high levels of transforming growth factor-beta expression in the joint. Clin Exp Immunol 146, 287-293, doi: 10.1111/j.1365-2249.2006.03204.x (2006).
    • (2006) Clin Exp Immunol , vol.146 , pp. 287-293
    • Marinova-Mutafchieva, L.1    Gabay, C.2    Funa, K.3    Williams, R.O.4
  • 17
    • 18644370435 scopus 로고    scopus 로고
    • Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis
    • Djouad, F. et al. Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis. Arthritis Rheum 52, 1595-1603, doi: 10.1002/art.21012 (2005).
    • (2005) Arthritis Rheum , vol.52 , pp. 1595-1603
    • Djouad, F.1
  • 18
    • 79958060173 scopus 로고    scopus 로고
    • Transforming growth factor beta-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis
    • Park, M. J. et al. Transforming growth factor beta-transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and osteoclastogenesis. Arthritis Rheum 63, 1668-1680, doi: 10.1002/art.30326 (2011).
    • (2011) Arthritis Rheum , vol.63 , pp. 1668-1680
    • Park, M.J.1
  • 19
    • 84902551116 scopus 로고    scopus 로고
    • Type 1 regulatory T cells specific for collagen-type II as an efficient cell-based therapy in arthritis
    • Asnagli, H. et al. Type 1 regulatory T cells specific for collagen-type II as an efficient cell-based therapy in arthritis. Arthritis Res Ther 16, R115, doi: 10.1186/ar4567 (2014).
    • (2014) Arthritis Res Ther , vol.16 , pp. R115
    • Asnagli, H.1
  • 20
    • 0346996879 scopus 로고    scopus 로고
    • The regulatory T cell family: Distinct subsets and their interrelations
    • Jonuleit, H. & Schmitt, E. The regulatory T cell family: distinct subsets and their interrelations. J Immunol 171, 6323-6327 (2003).
    • (2003) J Immunol , vol.171 , pp. 6323-6327
    • Jonuleit, H.1    Schmitt, E.2
  • 21
    • 2442450433 scopus 로고    scopus 로고
    • IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells
    • Vieira, P. L. et al. IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol 172, 5986-5993 (2004).
    • (2004) J Immunol , vol.172 , pp. 5986-5993
    • Vieira, P.L.1
  • 22
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva, M. & O'Garra, A. The regulation of IL-10 production by immune cells. Nat Rev Immunol 10, 170-181, doi: 10.1038/nri2711 (2010).
    • (2010) Nat Rev Immunol , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 23
    • 84873366721 scopus 로고    scopus 로고
    • On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation
    • Engela, A. U., Baan, C. C., Dor, F. J., Weimar, W. & Hoogduijn, M. J. On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation. Front Immunol 3, 126, doi: 10.3389/fimmu.2012.00126 (2012).
    • (2012) Front Immunol , vol.3 , pp. 126
    • Engela, A.U.1    Baan, C.C.2    Dor, F.J.3    Weimar, W.4    Hoogduijn, M.J.5
  • 24
    • 78649512322 scopus 로고    scopus 로고
    • Neutralization of IL-4 reverses the nonresponsiveness of CD4+ T cells to regulatory T-cell induction in non-responder mouse strains
    • Wang, J., Han, W. G., Foks, A. C., Huizinga, T. W. & Toes, R. E. Neutralization of IL-4 reverses the nonresponsiveness of CD4+ T cells to regulatory T-cell induction in non-responder mouse strains. Mol Immunol 48, 137-146, doi: 10.1016/j.molimm.2010.08.017 (2010).
    • (2010) Mol Immunol , vol.48 , pp. 137-146
    • Wang, J.1    Han, W.G.2    Foks, A.C.3    Huizinga, T.W.4    Toes, R.E.5
  • 25
    • 78650026309 scopus 로고    scopus 로고
    • The immunomodulatory properties of mesenchymal stem cells and their use for immunotherapy
    • Hoogduijn, M. J. et al. The immunomodulatory properties of mesenchymal stem cells and their use for immunotherapy. Int Immunopharmacol 10, 1496-1500, doi: 10.1016/j.intimp.2010.06.019 (2010).
    • (2010) Int Immunopharmacol , vol.10 , pp. 1496-1500
    • Hoogduijn, M.J.1
  • 26
    • 49649106257 scopus 로고    scopus 로고
    • IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
    • Polchert, D. et al. IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease. Eur J Immunol 38, 1745-1755, doi: 10.1002/eji.200738129 (2008).
    • (2008) Eur J Immunol , vol.38 , pp. 1745-1755
    • Polchert, D.1
  • 27
    • 84876186221 scopus 로고    scopus 로고
    • Interferon gamma suppresses collagen-induced arthritis by regulation of Th17 through the induction of indoleamine-2,3-deoxygenase
    • Lee, J. et al. Interferon gamma suppresses collagen-induced arthritis by regulation of Th17 through the induction of indoleamine-2,3-deoxygenase. PLos One 8, e60900, doi: 10.1371/journal.pone.0060900 (2013).
    • (2013) PLos One , vol.8 , pp. e60900
    • Lee, J.1
  • 28
    • 84861704495 scopus 로고    scopus 로고
    • Immunosuppressive properties of mesenchymal stem cells
    • Abumaree, M., Al Jumah, M., Pace, R. A. & Kalionis, B. Immunosuppressive properties of mesenchymal stem cells. Stem Cell Rev 8, 375-392, doi: 10.1007/s12015-011-9312-0 (2012).
    • (2012) Stem Cell Rev , vol.8 , pp. 375-392
    • Abumaree, M.1    Al Jumah, M.2    Pace, R.A.3    Kalionis, B.4
  • 29
    • 84879124355 scopus 로고    scopus 로고
    • Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation
    • Tatara, R. et al. Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation. Cytotherapy 13, 686-694, doi: 10.3109/14653249.2010.542456 (2011).
    • (2011) Cytotherapy , vol.13 , pp. 686-694
    • Tatara, R.1
  • 30
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot, J. D., Gavin, M. A. & Rudensky, A. Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4, 330-336, doi: 10.1038/ni904 (2003).
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 31
    • 67049097104 scopus 로고    scopus 로고
    • Developmental plasticity of Th17 and Treg cells
    • Lee, Y. K., Mukasa, R., Hatton, R. D. & Weaver, C. T. Developmental plasticity of Th17 and Treg cells. Curr Opin Immunol 21, 274-280, doi: 10.1016/j.coi.2009.05.021 (2009).
    • (2009) Curr Opin Immunol , vol.21 , pp. 274-280
    • Lee, Y.K.1    Mukasa, R.2    Hatton, R.D.3    Weaver, C.T.4
  • 32
    • 0034733039 scopus 로고    scopus 로고
    • Requirement for RORgamma in thymocyte survival and lymphoid organ development
    • Sun, Z. et al. Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science 288, 2369-2373 (2000).
    • (2000) Science , vol.288 , pp. 2369-2373
    • Sun, Z.1
  • 33
    • 42649115767 scopus 로고    scopus 로고
    • TH17 cells in development: An updated view of their molecular identity and genetic programming
    • Dong, C. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat Rev Immunol 8, 337-348, doi: 10.1038/nri2295 (2008).
    • (2008) Nat Rev Immunol , vol.8 , pp. 337-348
    • Dong, C.1
  • 34
    • 84868092910 scopus 로고    scopus 로고
    • Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells
    • Ju, J. H. et al. Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells. Arthritis Rheum 64, 3543-3552, doi: 10.1002/art.34601 (2012).
    • (2012) Arthritis Rheum , vol.64 , pp. 3543-3552
    • Ju, J.H.1
  • 35
    • 12344297883 scopus 로고    scopus 로고
    • Preferential expression and function of Toll-like receptor 3 in human astrocytes
    • Farina, C. et al. Preferential expression and function of Toll-like receptor 3 in human astrocytes. J Neuroimmunol 159, 12-19, doi: 10.1016/j.jneuroim.2004.09.009 (2005).
    • (2005) J Neuroimmunol , vol.159 , pp. 12-19
    • Farina, C.1
  • 36
    • 0037018104 scopus 로고    scopus 로고
    • In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
    • Barrat, F. J. et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195, 603-616 (2002).
    • (2002) J Exp Med , vol.195 , pp. 603-616
    • Barrat, F.J.1
  • 37
    • 65649089411 scopus 로고    scopus 로고
    • Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R
    • Opitz, C. A. et al. Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R. Stem Cells 27, 909-919, doi: 10.1002/stem.7 (2009).
    • (2009) Stem Cells , vol.27 , pp. 909-919
    • Opitz, C.A.1
  • 38
    • 77951635953 scopus 로고    scopus 로고
    • Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis
    • Ciorba, M. A. et al. Induction of IDO-1 by immunostimulatory DNA limits severity of experimental colitis. J Immunol 184, 3907-3916, doi: 10.4049/jimmunol.0900291 (2010).
    • (2010) J Immunol , vol.184 , pp. 3907-3916
    • Ciorba, M.A.1
  • 39
    • 0029118395 scopus 로고
    • IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes
    • Finbloom, D. S. & Winestock, K. D. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes. J Immunol 155, 1079-1090 (1995).
    • (1995) J Immunol , vol.155 , pp. 1079-1090
    • Finbloom, D.S.1    Winestock, K.D.2
  • 40
    • 79956302084 scopus 로고    scopus 로고
    • The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells
    • Opitz, C. A. et al. The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells. PLos One 6, e19823, doi: 10.1371/journal.pone.0019823 (2011).
    • (2011) PLos One , vol.6 , pp. e19823
    • Opitz, C.A.1
  • 41
    • 85027926151 scopus 로고    scopus 로고
    • The immunomodulatory properties of mesenchymal stem cells
    • Marigo, I. & Dazzi, F. The immunomodulatory properties of mesenchymal stem cells. Semin Immunopathol 33, 593-602, doi: 10.1007/s00281-011-0267-7 (2011).
    • (2011) Semin Immunopathol , vol.33 , pp. 593-602
    • Marigo, I.1    Dazzi, F.2
  • 42
    • 77649298684 scopus 로고    scopus 로고
    • Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis
    • Schurgers, E., Kelchtermans, H., Mitera, T., Geboes, L. & Matthys, P. Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis. Arthritis Res Ther 12, R31, doi: 10.1186/ar2939 (2010).
    • (2010) Arthritis Res Ther , vol.12 , pp. R31
    • Schurgers, E.1    Kelchtermans, H.2    Mitera, T.3    Geboes, L.4    Matthys, P.5
  • 43
    • 74549151228 scopus 로고    scopus 로고
    • Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6
    • Chen, B. et al. Flk-1+ mesenchymal stem cells aggravate collagen-induced arthritis by up-regulating interleukin-6. Clin Exp Immunol 159, 292-302, doi: 10.1111/j.1365-2249.2009.04069.x (2010).
    • (2010) Clin Exp Immunol , vol.159 , pp. 292-302
    • Chen, B.1
  • 44
    • 84881104041 scopus 로고    scopus 로고
    • The synergistic immunoregulatory effects of culture-expanded mesenchymal stromal cells and CD4(+)25(+)Foxp3+ regulatory T cells on skin allograft rejection
    • Lee, J. H. et al. The synergistic immunoregulatory effects of culture-expanded mesenchymal stromal cells and CD4(+)25(+)Foxp3+ regulatory T cells on skin allograft rejection. PLos One 8, e70968, doi: 10.1371/journal.pone.0070968 (2013).
    • (2013) PLos One , vol.8 , pp. e70968
    • Lee, J.H.1
  • 45
    • 84898917571 scopus 로고    scopus 로고
    • Combination cell therapy using mesenchymal stem cells and regulatory T-cells provides a synergistic immunomodulatory effect associated with reciprocal regulation of TH1/TH2 and th17/treg cells in a murine acute graft-versus-host disease model
    • Lim, J. Y. et al. Combination cell therapy using mesenchymal stem cells and regulatory T-cells provides a synergistic immunomodulatory effect associated with reciprocal regulation of TH1/TH2 and th17/treg cells in a murine acute graft-versus-host disease model. Cell Transplant 23, 703-714, doi: 10.3727/096368913X664577 (2014).
    • (2014) Cell Transplant , vol.23 , pp. 703-714
    • Lim, J.Y.1
  • 46
    • 84907912531 scopus 로고    scopus 로고
    • Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T Cells for solid-Organ transplant tolerance
    • Im, K. I. et al. Induction of mixed chimerism using combinatory cell-based immune modulation with mesenchymal stem cells and regulatory T Cells for solid-Organ transplant tolerance. Stem Cells Dev, doi: 10.1089/scd.2013.0617 (2014).
    • (2014) Stem Cells Dev
    • Im, K.I.1
  • 47
    • 78650764391 scopus 로고    scopus 로고
    • Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production
    • van Hamburg, J. P. et al. Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production. Arthritis Rheum 63, 73-83, doi: 10.1002/art.30093 (2011).
    • (2011) Arthritis Rheum , vol.63 , pp. 73-83
    • Van Hamburg, J.P.1
  • 48
    • 84892433295 scopus 로고    scopus 로고
    • Immunobiology of mesenchymal stem cells
    • Ma, S. et al. Immunobiology of mesenchymal stem cells. Cell Death Differ 21, 216-225, doi: 10.1038/cdd.2013.158 (2014).
    • (2014) Cell Death Differ , vol.21 , pp. 216-225
    • Ma, S.1
  • 49
    • 82755165048 scopus 로고    scopus 로고
    • Type I IFN promotes IL-10 production from T cells to suppress Th17 cells and Th17-associated autoimmune inflammation
    • Zhang, L., Yuan, S., Cheng, G. & Guo, B. Type I IFN promotes IL-10 production from T cells to suppress Th17 cells and Th17-associated autoimmune inflammation. Plos One 6, e28432, doi: 10.1371/journal.pone.0028432 (2011).
    • (2011) Plos One , vol.6 , pp. e28432
    • Zhang, L.1    Yuan, S.2    Cheng, G.3    Guo, B.4
  • 50
    • 84885783510 scopus 로고    scopus 로고
    • Type I interferon potentiates T-cell receptor mediated induction of IL-10-producing CD4(+) T cells
    • Corre, B. et al. Type I interferon potentiates T-cell receptor mediated induction of IL-10-producing CD4(+) T cells. Eur J Immunol 43, 2730-2740, doi: 10.1002/eji.201242977 (2013).
    • (2013) Eur J Immunol , vol.43 , pp. 2730-2740
    • Corre, B.1
  • 51
    • 84887462082 scopus 로고    scopus 로고
    • Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation
    • Stewart, C. A. et al. Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation. J Clin Invest 123, 4859-4874, doi: 10.1172/JCI65180 (2013).
    • (2013) J Clin Invest , vol.123 , pp. 4859-4874
    • Stewart, C.A.1
  • 52
    • 61449210913 scopus 로고    scopus 로고
    • A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow
    • Soleimani, M. & Nadri, S. A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow. Nat Protoc 4, 102-106, doi: 10.1038/nprot.2008.221 (2009).
    • (2009) Nat Protoc , vol.4 , pp. 102-106
    • Soleimani, M.1    Nadri, S.2
  • 53
    • 0036222483 scopus 로고    scopus 로고
    • Suppression of collagen-induced arthritis by single administration of poly(lactic-co-glycolic acid) nanoparticles entrapping type II collagen: A novel treatment strategy for induction of oral tolerance
    • Kim, W. U. et al. Suppression of collagen-induced arthritis by single administration of poly(lactic-co-glycolic acid) nanoparticles entrapping type II collagen: a novel treatment strategy for induction of oral tolerance. Arthritis Rheum 46, 1109-1120 (2002).
    • (2002) Arthritis Rheum , vol.46 , pp. 1109-1120
    • Kim, W.U.1
  • 54
    • 34250162097 scopus 로고    scopus 로고
    • Collagen-induced arthritis
    • Brand, D. D., Latham, K. A. & Rosloniec, E. F. Collagen-induced arthritis. Nat Protoc 2, 1269-1275, doi: 10.1038/nprot.2007.173 (2007).
    • (2007) Nat Protoc , vol.2 , pp. 1269-1275
    • Brand, D.D.1    Latham, K.A.2    Rosloniec, E.F.3
  • 55
    • 24744435115 scopus 로고    scopus 로고
    • Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
    • Camps, M. et al. Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat Med 11, 936-943, doi: 10.1038/nm1284 (2005).
    • (2005) Nat Med , vol.11 , pp. 936-943
    • Camps, M.1


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