-
1
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994; 266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
-
2
-
-
84886718942
-
The sex hormone system in carriers of BRCA1/2 mutations: A case-control study
-
Widschwendter M, Rosenthal AN, Philpott S , et al. The sex hormone system in carriers of BRCA1/2 mutations: a case-control study. Lancet Oncol 2013; 14:1226-1232.
-
(2013)
Lancet Oncol
, vol.14
, pp. 1226-1232
-
-
Widschwendter, M.1
Rosenthal, A.N.2
Philpott, S.3
-
3
-
-
33845315093
-
Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist
-
Poole AJ, Li Y, Kim Y, Lin SC, Lee WH, Lee EY. Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist. Science 2006; 314:1467-1470.
-
(2006)
Science
, vol.314
, pp. 1467-1470
-
-
Poole, A.J.1
Li, Y.2
Kim, Y.3
Lin, S.C.4
Lee, W.H.5
Lee, E.Y.6
-
4
-
-
0033568341
-
RANK is essential for osteoclast and lymph node development
-
Dougall WC, Glaccum M, Charrier K, et al. RANK is essential for osteoclast and lymph node development. Genes Dev 1999; 13:2412-2424.
-
(1999)
Genes Dev
, vol.13
, pp. 2412-2424
-
-
Dougall, W.C.1
Glaccum, M.2
Charrier, K.3
-
5
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymphnode organogenesis
-
Kong YY, Yoshida H, Sarosi I, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymphnode organogenesis. Nature 1999; 397:315-323.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
-
6
-
-
69049083492
-
Denosumab for prevention of fractures in postmenopausal women with osteoporosis
-
Cummings SR, San Martin J, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 2009; 361:756-765
-
(2009)
N Engl J Med
, vol.361
, pp. 756-765
-
-
Cummings, S.R.1
San Martin, J.2
McClung, M.R.3
-
7
-
-
33344469853
-
Denosumab in postmenopausal women with low bone mineral density
-
McClung MR, Lewiecki EM, Cohen SB, et al. Denosumab in postmenopausal women with low bone mineral density. N Engl J Med 2006; 354:821-831.
-
(2006)
N Engl J Med
, vol.354
, pp. 821-831
-
-
McClung, M.R.1
Lewiecki, E.M.2
Cohen, S.B.3
-
8
-
-
69049105440
-
Denosumab in men receiving androgen-deprivation therapy for prostate cancer
-
Smith MR, Egerdie B, Hernandez Toriz N, et al. Denosumab in men receiving androgen-deprivation therapy for prostate cancer. N Engl J Med 2009; 361:745-755.
-
(2009)
N Engl J Med
, vol.361
, pp. 745-755
-
-
Smith, M.R.1
Egerdie, B.2
Hernandez Toriz, N.3
-
9
-
-
79955476478
-
RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis
-
Schramek D, Sigl V, Penninger JM. RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis. Trends Endocrinol Metab 2011; 22:188-194.
-
(2011)
Trends Endocrinol Metab
, vol.22
, pp. 188-194
-
-
Schramek, D.1
Sigl, V.2
Penninger, J.M.3
-
10
-
-
0034730327
-
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development
-
Fata JE, Kong YY, Li J, et al. The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development. Cell 2000; 103:41-50.
-
(2000)
Cell
, vol.103
, pp. 41-50
-
-
Fata, J.E.1
Kong, Y.Y.2
Li, J.3
-
11
-
-
77953388315
-
Progesterone induces adult mammary stem cell expansion
-
Joshi PA, Jackson HW, Beristain AG, et al. Progesterone induces adult mammary stem cell expansion. Nature 2010; 465:803-807.
-
(2010)
Nature
, vol.465
, pp. 803-807
-
-
Joshi, P.A.1
Jackson, H.W.2
Beristain, A.G.3
-
12
-
-
77953384898
-
Control of mammary stem cell function by steroid hormone signalling
-
Asselin-Labat ML, Vaillant F, Sheridan JM, et al. Control of mammary stem cell function by steroid hormone signalling. Nature 2010; 465:798-802.
-
(2010)
Nature
, vol.465
, pp. 798-802
-
-
Asselin-Labat, M.L.1
Vaillant, F.2
Sheridan, J.M.3
-
13
-
-
78149284013
-
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
-
Schramek D, Leibbrandt A, Sigl V, et al. Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature 2010; 468:98-102.
-
(2010)
Nature
, vol.468
, pp. 98-102
-
-
Schramek, D.1
Leibbrandt, A.2
Sigl, V.3
-
14
-
-
78149284767
-
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
-
Gonzalez-Suarez E, Jacob AP, Jones J, et al RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis. Nature 2010; 468:103-107.
-
(2010)
Nature
, vol.468
, pp. 103-107
-
-
Gonzalez-Suarez, E.1
Jacob, A.P.2
Jones, J.3
-
16
-
-
70849096810
-
Central control of fever and female body temperature by RANKL/RANK
-
Hanada R, Leibbrandt A, Hanada T, et al. Central control of fever and female body temperature by RANKL/RANK. Nature 2009; 462:505-509.
-
(2009)
Nature
, vol.462
, pp. 505-509
-
-
Hanada, R.1
Leibbrandt, A.2
Hanada, T.3
-
17
-
-
0042836597
-
Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues
-
Berton TR, Matsumoto T, Page A, et al. Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues. Oncogene 2003; 22:5415-5426.
-
(2003)
Oncogene
, vol.22
, pp. 5415-5426
-
-
Berton, T.R.1
Matsumoto, T.2
Page, A.3
-
18
-
-
34547496282
-
Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer
-
Liu X, Holstege H, van der Gulden H, et al. Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer. Proc Natl Acad Sci USA 2007; 104:12111-12116.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12111-12116
-
-
Liu, X.1
Holstege, H.2
Van Der Gulden, H.3
-
19
-
-
2442701845
-
Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis
-
Lin SC, Lee KF, Nikitin AY, et al. Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis. Cancer Res 2004; 64:3525-3532.
-
(2004)
Cancer Res
, vol.64
, pp. 3525-3532
-
-
Lin, S.C.1
Lee, K.F.2
Nikitin, A.Y.3
-
20
-
-
84887398348
-
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
-
Pfefferle AD, Herschkowitz JI, Usary J, et al. Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol 2013; 14:R125.
-
(2013)
Genome Biol
, vol.14
, pp. R125
-
-
Pfefferle, A.D.1
Herschkowitz, J.I.2
Usary, J.3
-
21
-
-
84875741884
-
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk
-
Couch FJ, Wang X, McGuffog L, et al. Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet 2013; 9:e1003212.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003212
-
-
Couch, F.J.1
Wang, X.2
McGuffog, L.3
-
22
-
-
84875733563
-
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk
-
Gaudet MM, Kuchenbaecker KB, Vijai J, et al. Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk. PLoS Genet 2013; 9:e1003173.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003173
-
-
Gaudet, M.M.1
Kuchenbaecker, K.B.2
Vijai, J.3
-
23
-
-
84860331458
-
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals loci associated with risk of fracture
-
Estrada K, Styrkarsdottir U, Evangelou E, et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals loci associated with risk of fracture. Nat Genet 2012; 44:491-501.
-
(2012)
Nat Genet
, vol.44
, pp. 491-501
-
-
Estrada, K.1
Styrkarsdottir, U.2
Evangelou, E.3
-
24
-
-
70350646912
-
Genetic Factors for Osteoporosis (GEFOS) Consortium, Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
-
Rivadeneira F, Styrkarsdottir U, Estrada K, et al. Genetic Factors for Osteoporosis (GEFOS) Consortium, Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009; 41:1199-1206.
-
(2009)
Nat Genet
, vol.41
, pp. 1199-1206
-
-
Rivadeneira, F.1
Styrkarsdottir, U.2
Estrada, K.3
-
25
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas N
-
Cancer Genome Atlas N. Comprehensive molecular portraits of human breast tumours. Nature 2012; 490:61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
26
-
-
84954304973
-
Rankl impairs lactogenic differentiation through inhibition of the prolactin/Stat5 pathway at midgestation
-
Cordero A, Pellegrini P, Sanz-Moreno A, et al. Rankl impairs lactogenic differentiation through inhibition of the prolactin/Stat5 pathway at midgestation. Stem Cells 2016; 34:1027-1039.
-
(2016)
Stem Cells
, vol.34
, pp. 1027-1039
-
-
Cordero, A.1
Pellegrini, P.2
Sanz-Moreno, A.3
-
27
-
-
84875079780
-
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
-
Lee HJ, Gallego-Ortega D, Ledger A, et al. Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells. Development 2013; 140:1397-1401.
-
(2013)
Development
, vol.140
, pp. 1397-1401
-
-
Lee, H.J.1
Gallego-Ortega, D.2
Ledger, A.3
-
28
-
-
84886419490
-
Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells
-
Obr AE, Grimm SL, Bishop KA, Pike JW, Lydon JP, Edwards DP. Progesterone receptor and Stat5 signaling cross talk through RANKL in mammary epithelial cells. Mol Endocrinol 2013; 27:1808-1824.
-
(2013)
Mol Endocrinol
, vol.27
, pp. 1808-1824
-
-
Obr, A.E.1
Grimm, S.L.2
Bishop, K.A.3
Pike, J.W.4
Lydon, J.P.5
Edwards, D.P.6
-
29
-
-
0033591295
-
BRCA1 inhibition of estrogen receptor signaling in transfected cells
-
Fan S, Wang J, Yuan R, Rosen EM, et al. BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science 1999; 284:1354-1356.
-
(1999)
Science
, vol.284
, pp. 1354-1356
-
-
Fan, S.1
Wang, J.2
Yuan, R.3
Rosen, E.M.4
-
30
-
-
29444434177
-
The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells
-
Ma Y, Katiyar P, Jones LP, et al. The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells. Mol Endocrinol 2006; 20:14-34.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 14-34
-
-
Ma, Y.1
Katiyar, P.2
Jones, L.P.3
-
31
-
-
19944401190
-
Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer
-
Jones LP, Li M, Halama ED, et al. Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer. Oncogene 2005; 24:3554-3562.
-
(2005)
Oncogene
, vol.24
, pp. 3554-3562
-
-
Jones, L.P.1
Li, M.2
Halama, E.D.3
-
32
-
-
84878113369
-
The shaping and functional consequences of the microRNA landscape in breast cancer
-
Dvinge H, Git A, Graf S, et al. The shaping and functional consequences of the microRNA landscape in breast cancer. Nature 2013; 497:378-382.
-
(2013)
Nature
, vol.497
, pp. 378-382
-
-
Dvinge, H.1
Git, A.2
Graf, S.3
-
33
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
-
Srinivas S, Watanabe T, Lin CS, et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 2001; 1:4.
-
(2001)
BMC Dev Biol
, vol.1
, pp. 4
-
-
Srinivas, S.1
Watanabe, T.2
Lin, C.S.3
-
34
-
-
84937959927
-
STAT3 regulated ARF expression suppresses prostate cancer metastasis
-
Pencik J, Schlederer M, Gruber W, et al. STAT3 regulated ARF expression suppresses prostate cancer metastasis. Nat Commun 2015; 6:7736.
-
(2015)
Nat Commun
, vol.6
, pp. 7736
-
-
Pencik, J.1
Schlederer, M.2
Gruber, W.3
-
35
-
-
84872035480
-
Proliferative and nonproliferative lesions of the rat and mouse mammary, Zymbals, preputial, and clitoral glands
-
Rudmann D, Cardiff R, Chouinard L, et al. Proliferative and nonproliferative lesions of the rat and mouse mammary, Zymbals, preputial, and clitoral glands. Toxicol Pathol 2012; 40:7S-39S.
-
(2012)
Toxicol Pathol
, vol.40
, pp. 7S-39S
-
-
Rudmann, D.1
Cardiff, R.2
Chouinard, L.3
-
36
-
-
0034696279
-
The mammary pathology of genetically engineered mice: The consensus report and recommendations from the Annapolis meeting
-
Cardiff RD, Anver MR, Gusterson BA, et al. The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting. Oncogene 2000; 19:968-988.
-
(2000)
Oncogene
, vol.19
, pp. 968-988
-
-
Cardiff, R.D.1
Anver, M.R.2
Gusterson, B.A.3
-
37
-
-
13444272959
-
Deregulated estrogen receptor a expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ
-
Frech MS, Halama ED, Tilli MT, et al. Deregulated estrogen receptor a expression in mammary epithelial cells of transgenic mice results in the development of ductal carcinoma in situ. Cancer Res 2005; 65:681-685.
-
(2005)
Cancer Res
, vol.65
, pp. 681-685
-
-
Frech, M.S.1
Halama, E.D.2
Tilli, M.T.3
-
38
-
-
57349148680
-
A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability
-
Eirew P, Stingl J, Raouf A, et al. A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability. Nat Med 2008; 14:1384-1389.
-
(2008)
Nat Med
, vol.14
, pp. 1384-1389
-
-
Eirew, P.1
Stingl, J.2
Raouf, A.3
-
39
-
-
16644364791
-
Enzymatic dissociation and culture of normal human mammary tissue to detect progenitor activity
-
Stingl J, Emerman JT, Eaves CJ. Enzymatic dissociation and culture of normal human mammary tissue to detect progenitor activity. Methods Mol Biol 2005; 290:249-263.
-
(2005)
Methods Mol Biol
, vol.290
, pp. 249-263
-
-
Stingl, J.1
Emerman, J.T.2
Eaves, C.J.3
-
40
-
-
84897541350
-
XBP1 promotes triple-negative breast cancer by controlling the HIF1alpha pathway
-
Chen X, Iliopoulos D, Zhang Q, et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1alpha pathway. Nature 2014; 508:103-107.
-
(2014)
Nature
, vol.508
, pp. 103-107
-
-
Chen, X.1
Iliopoulos, D.2
Zhang, Q.3
-
41
-
-
80053152058
-
Aminoacyl-tRNA synthetases and tumorigenesis: More than housekeeping
-
Kim S, You S, Hwang D. Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping. Nat Rev Cancer 2011;11:708-718.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 708-718
-
-
Kim, S.1
You, S.2
Hwang, D.3
-
42
-
-
84937527027
-
RANK signaling amplifies WNT-responsive mammary progenitors through R-SPONDIN1
-
Joshi PA, Waterhouse PD, Kannan N, et al. RANK signaling amplifies WNT-responsive mammary progenitors through R-SPONDIN1. Stem Cell Reports 2015; 5:31-44.
-
(2015)
Stem Cell Reports
, vol.5
, pp. 31-44
-
-
Joshi, P.A.1
Waterhouse, P.D.2
Kannan, N.3
-
43
-
-
34548863946
-
Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors
-
Herschkowitz JI, Simin K, Weigman VJ, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol 2007; 8:R76.
-
(2007)
Genome Biol
, vol.8
, pp. R76
-
-
Herschkowitz, J.I.1
Simin, K.2
Weigman, V.J.3
-
44
-
-
84859098571
-
The sva package for removing batch effects and other unwanted variation in high-throughput experiments
-
Leek JT, Johnson WE, Parker HS, Jaffe AE, Storey JD. The sva package for removing batch effects and other unwanted variation in high-throughput experiments. Bioinformatics 2012; 28:882-883.
-
(2012)
Bioinformatics
, vol.28
, pp. 882-883
-
-
Leek, J.T.1
Johnson, W.E.2
Parker, H.S.3
Jaffe, A.E.4
Storey, J.D.5
-
45
-
-
84864579879
-
TNBCtype: A subtyping tool for triple-negative breast cancer
-
Chen X, Li J, Gray WH, et al. TNBCtype: a subtyping tool for triple-negative breast cancer. Cancer Inform 2012; 11:147-156.
-
(2012)
Cancer Inform
, vol.11
, pp. 147-156
-
-
Chen, X.1
Li, J.2
Gray, W.H.3
-
46
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, Bauer JA, Chen X, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011; 121:2750-2767.
-
(2011)
J Clin Invest
, vol.121
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
|