메뉴 건너뛰기




Volumn 7, Issue 13, 2016, Pages 15554-15565

Protective effect of a-lipoic acid against radiation-induced fibrosis in mice

Author keywords

A lipoic acid; Acetylation; NF B; PAI 1; Radiation induced fibrosis

Indexed keywords

HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SYNAPTOTAGMIN I; THIOCTIC ACID; TRANSFORMING GROWTH FACTOR BETA1; ANTIOXIDANT; RADIOPROTECTIVE AGENT;

EID: 84971665317     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.6952     Document Type: Article
Times cited : (23)

References (54)
  • 1
    • 33747826874 scopus 로고    scopus 로고
    • Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
    • Bentzen SM. Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology. Nature reviews Cancer. 2006; 6:702-713.
    • (2006) Nature reviews Cancer. , vol.6 , pp. 702-713
    • Bentzen, S.M.1
  • 2
    • 0042527740 scopus 로고    scopus 로고
    • Late radiation-related fibrosis: pathogenesis, manifestations, and current management
    • O'Sullivan B, Levin W. Late radiation-related fibrosis: pathogenesis, manifestations, and current management. Seminars in radiation oncology. 2003; 13:274-289.
    • (2003) Seminars in radiation oncology. , vol.13 , pp. 274-289
    • O'Sullivan, B.1    Levin, W.2
  • 4
    • 0043029520 scopus 로고    scopus 로고
    • Trends and advances in cancer survivorship research: challenge and opportunity
    • Aziz NM, Rowland JH. Trends and advances in cancer survivorship research: challenge and opportunity. Seminars in radiation oncology. 2003; 13:248-266.
    • (2003) Seminars in radiation oncology. , vol.13 , pp. 248-266
    • Aziz, N.M.1    Rowland, J.H.2
  • 5
    • 0028066981 scopus 로고
    • Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trial
    • Delanian S, Baillet F, Huart J, Lefaix JL, Maulard C, Housset M. Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trial. Radiotherapy and oncology: 1994; 32:12-20.
    • (1994) Radiotherapy and oncology: , vol.32 , pp. 12-20
    • Delanian, S.1    Baillet, F.2    Huart, J.3    Lefaix, J.L.4    Maulard, C.5    Housset, M.6
  • 6
    • 33644842542 scopus 로고    scopus 로고
    • Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis
    • Delanian S, Porcher R, Rudant J, Lefaix JL. Kinetics of response to long-term treatment combining pentoxifylline and tocopherol in patients with superficial radiation-induced fibrosis. Journal of clinical oncology: 2005; 23: 8570-8579.
    • (2005) Journal of clinical oncology: , vol.23 , pp. 8570-8579
    • Delanian, S.1    Porcher, R.2    Rudant, J.3    Lefaix, J.L.4
  • 8
    • 0002908647 scopus 로고
    • Crystalline alpha-lipoic acid; a catalytic agent associated with pyruvate dehydrogenase
    • Reed LJ, De BB, Gunsalus IC, Hornberger CS, Jr. Crystalline alpha-lipoic acid; a catalytic agent associated with pyruvate dehydrogenase. Science. 1951; 114:93-94.
    • (1951) Science. , vol.114 , pp. 93-94
    • Reed, L.J.1    De, B.B.2    Gunsalus, I.C.3    Hornberger, C.S.4
  • 12
    • 84858073258 scopus 로고    scopus 로고
    • Protective effects of curcumin, alpha-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats
    • Morsy MA, Abdalla AM, Mahmoud AM, Abdelwahab SA, Mahmoud ME. Protective effects of curcumin, alpha-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats. Journal of physiology and biochemistry. 2012; 68:29-35.
    • (2012) Journal of physiology and biochemistry. , vol.68 , pp. 29-35
    • Morsy, M.A.1    Abdalla, A.M.2    Mahmoud, A.M.3    Abdelwahab, S.A.4    Mahmoud, M.E.5
  • 15
    • 0034283837 scopus 로고    scopus 로고
    • The Rel/NF-kappa B family: friend and foe
    • Perkins ND. The Rel/NF-kappa B family: friend and foe. Trends in biochemical sciences. 2000; 25:434-440.
    • (2000) Trends in biochemical sciences. , vol.25 , pp. 434-440
    • Perkins, N.D.1
  • 16
    • 0037011056 scopus 로고    scopus 로고
    • Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB
    • Chen LF, Mu Y, Greene WC. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB. The EMBO journal. 2002; 21:6539-6548.
    • (2002) The EMBO journal. , vol.21 , pp. 6539-6548
    • Chen, L.F.1    Mu, Y.2    Greene, W.C.3
  • 19
    • 14544269951 scopus 로고    scopus 로고
    • NF-kappaB in human disease: current inhibitors and prospects for de novo structure based design of inhibitors
    • Pande V, Ramos MJ. NF-kappaB in human disease: current inhibitors and prospects for de novo structure based design of inhibitors. Current medicinal chemistry. 2005; 12: 357-374.
    • (2005) Current medicinal chemistry. , vol.12 , pp. 357-374
    • Pande, V.1    Ramos, M.J.2
  • 20
    • 4043146501 scopus 로고    scopus 로고
    • Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression
    • Balasubramanyam K, Altaf M, Varier RA, Swaminathan V, Ravindran A, Sadhale PP, Kundu TK. Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression. The Journal of biological chemistry. 2004; 279:33716-33726.
    • (2004) The Journal of biological chemistry. , vol.279 , pp. 33716-33726
    • Balasubramanyam, K.1    Altaf, M.2    Varier, R.A.3    Swaminathan, V.4    Ravindran, A.5    Sadhale, P.P.6    Kundu, T.K.7
  • 21
    • 10944243759 scopus 로고    scopus 로고
    • Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
    • Balasubramanyam K, Varier RA, Altaf M, Swaminathan V, Siddappa NB, Ranga U, Kundu TK. Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. The Journal of biological chemistry. 2004; 279:51163-51171.
    • (2004) The Journal of biological chemistry. , vol.279 , pp. 51163-51171
    • Balasubramanyam, K.1    Varier, R.A.2    Altaf, M.3    Swaminathan, V.4    Siddappa, N.B.5    Ranga, U.6    Kundu, T.K.7
  • 23
    • 46749127067 scopus 로고    scopus 로고
    • Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis
    • Sung B, Pandey MK, Ahn KS, Yi T, Chaturvedi MM, Liu M, Aggarwal BB. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. Blood. 2008; 111:4880-4891.
    • (2008) Blood. , vol.111 , pp. 4880-4891
    • Sung, B.1    Pandey, M.K.2    Ahn, K.S.3    Yi, T.4    Chaturvedi, M.M.5    Liu, M.6    Aggarwal, B.B.7
  • 24
    • 45749112986 scopus 로고    scopus 로고
    • p300 (histone acetyltransferase) biomarker predicts prostate cancer biochemical recurrence and correlates with changes in epithelia nuclear size and shape
    • Isharwal S, Miller MC, Marlow C, Makarov DV, Partin AW, Veltri RW. p300 (histone acetyltransferase) biomarker predicts prostate cancer biochemical recurrence and correlates with changes in epithelia nuclear size and shape. The Prostate. 2008; 68:1097-1104.
    • (2008) The Prostate. , vol.68 , pp. 1097-1104
    • Isharwal, S.1    Miller, M.C.2    Marlow, C.3    Makarov, D.V.4    Partin, A.W.5    Veltri, R.W.6
  • 25
    • 79951575880 scopus 로고    scopus 로고
    • alpha-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF, TGF-beta
    • Foo NP, Lin SH, Lee YH, Wu MJ, Wang YJ. alpha-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF, TGF-beta. Toxicology. 2011; 282:39-46.
    • (2011) Toxicology. , vol.282 , pp. 39-46
    • Foo, N.P.1    Lin, S.H.2    Lee, Y.H.3    Wu, M.J.4    Wang, Y.J.5
  • 26
    • 0035158577 scopus 로고    scopus 로고
    • Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells
    • Zhang WJ, Frei B. Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells. FASEB journal: 2001; 15:2423-2432.
    • (2001) FASEB journal: , vol.15 , pp. 2423-2432
    • Zhang, W.J.1    Frei, B.2
  • 27
    • 0035008915 scopus 로고    scopus 로고
    • Inhibition of transcription factor NF-kappaB reduces matrix metalloproteinase -1, -3 and -9 production by vascular smooth muscle cells
    • Bond M, Chase AJ, Baker AH, Newby AC. Inhibition of transcription factor NF-kappaB reduces matrix metalloproteinase -1, -3 and -9 production by vascular smooth muscle cells. Cardiovascular research. 2001; 50: 556-565.
    • (2001) Cardiovascular research. , vol.50 , pp. 556-565
    • Bond, M.1    Chase, A.J.2    Baker, A.H.3    Newby, A.C.4
  • 28
    • 84155184239 scopus 로고    scopus 로고
    • AMP-activated protein kinase inhibits TGF-beta-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300
    • Lim JY, Oh MA, Kim WH, Sohn HY, Park SI. AMP-activated protein kinase inhibits TGF-beta-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300. Journal of cellular physiology. 2012; 227:1081-1089.
    • (2012) Journal of cellular physiology. , vol.227 , pp. 1081-1089
    • Lim, J.Y.1    Oh, M.A.2    Kim, W.H.3    Sohn, H.Y.4    Park, S.I.5
  • 29
    • 73849102273 scopus 로고    scopus 로고
    • Gallic acid suppresses lipopolysaccharide-induced nuclear factor-kappaB signaling by preventing RelA acetylation in A549 lung cancer cells
    • Choi KC, Lee YH, Jung MG, Kwon SH, Kim MJ, Jun WJ, Lee J, Lee JM, Yoon HG. Gallic acid suppresses lipopolysaccharide-induced nuclear factor-kappaB signaling by preventing RelA acetylation in A549 lung cancer cells. Mol Cancer Res. 2009; 7:2011-2021.
    • (2009) Mol Cancer Res. , vol.7 , pp. 2011-2021
    • Choi, K.C.1    Lee, Y.H.2    Jung, M.G.3    Kwon, S.H.4    Kim, M.J.5    Jun, W.J.6    Lee, J.7    Lee, J.M.8    Yoon, H.G.9
  • 32
    • 70349331686 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
    • Ghosh AK, Bhattacharyya S, Wei J, Kim S, Barak Y, Mori Y, Varga J. Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator. FASEB journal: 2009; 23:2968-2977.
    • (2009) FASEB journal: , vol.23 , pp. 2968-2977
    • Ghosh, A.K.1    Bhattacharyya, S.2    Wei, J.3    Kim, S.4    Barak, Y.5    Mori, Y.6    Varga, J.7
  • 33
    • 35848951176 scopus 로고    scopus 로고
    • The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis
    • Ghosh AK, Varga J. The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis. Journal of cellular physiology. 2007; 213:663-671.
    • (2007) Journal of cellular physiology. , vol.213 , pp. 663-671
    • Ghosh, A.K.1    Varga, J.2
  • 34
    • 84898773559 scopus 로고    scopus 로고
    • Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/Akt-dependent NF-κB/p300 activation
    • Cheng SE, Lee IT, Lin CC, Hsiao LD, Yang CM. Thrombin induces ICAM-1 expression in human lung epithelial cells via c-Src/PDGFR/PI3K/Akt-dependent NF-κB/p300 activation. Clin Sci (Lond). 2014; 127:171-183.
    • (2014) Clin Sci (Lond). , vol.127 , pp. 171-183
    • Cheng, S.E.1    Lee, I.T.2    Lin, C.C.3    Hsiao, L.D.4    Yang, C.M.5
  • 36
    • 0037036387 scopus 로고    scopus 로고
    • Ets1 is an effector of the transforming growth factor beta (TGF-beta) signaling pathway and an antagonist of the profibrotic effects of TGF-beta
    • Czuwara-Ladykowska J, Sementchenko VI, Watson DK, Trojanowska M. Ets1 is an effector of the transforming growth factor beta (TGF-beta) signaling pathway and an antagonist of the profibrotic effects of TGF-beta. The Journal of biological chemistry. 2002; 277:20399-20408.
    • (2002) The Journal of biological chemistry. , vol.277 , pp. 20399-20408
    • Czuwara-Ladykowska, J.1    Sementchenko, V.I.2    Watson, D.K.3    Trojanowska, M.4
  • 37
    • 78650782799 scopus 로고    scopus 로고
    • High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma
    • Li M, Luo RZ, Chen JW, Cao Y, Lu JB, He JH, Wu QL, Cai MY. High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma. J Transl Med. 2011; 9:5.
    • (2011) J Transl Med. , vol.9 , pp. 5
    • Li, M.1    Luo, R.Z.2    Chen, J.W.3    Cao, Y.4    Lu, J.B.5    He, J.H.6    Wu, Q.L.7    Cai, M.Y.8
  • 39
    • 33947577419 scopus 로고    scopus 로고
    • Current management for late normal tissue injury: radiation-induced fibrosis and necrosis
    • Delanian S, Lefaix JL. Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. Seminars in radiation oncology. 2007; 17:99-107.
    • (2007) Seminars in radiation oncology. , vol.17 , pp. 99-107
    • Delanian, S.1    Lefaix, J.L.2
  • 41
    • 0034691764 scopus 로고    scopus 로고
    • Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators
    • Ghosh AK, Yuan W, Mori Y, Varga J. Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators. Oncogene. 2000; 19:3546-3555.
    • (2000) Oncogene. , vol.19 , pp. 3546-3555
    • Ghosh, A.K.1    Yuan, W.2    Mori, Y.3    Varga, J.4
  • 45
    • 84902549830 scopus 로고    scopus 로고
    • C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe
    • Oike T, Komachi M, Ogiwara H, Amornwichet N, Saitoh Y, Torikai K, Kubo N, Nakano T, Kohno T. C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe. Radiotherapy and oncology: 2014; 111:222-227.
    • (2014) Radiotherapy and oncology: , vol.111 , pp. 222-227
    • Oike, T.1    Komachi, M.2    Ogiwara, H.3    Amornwichet, N.4    Saitoh, Y.5    Torikai, K.6    Kubo, N.7    Nakano, T.8    Kohno, T.9
  • 46
    • 84887904057 scopus 로고    scopus 로고
    • Molecular mechanisms and treatment of radiation-induced lung fibrosis
    • Ding NH, Li JJ, Sun LQ. Molecular mechanisms and treatment of radiation-induced lung fibrosis. Curr Drug Targets. 2013; 14:1347-1356.
    • (2013) Curr Drug Targets. , vol.14 , pp. 1347-1356
    • Ding, N.H.1    Li, J.J.2    Sun, L.Q.3
  • 47
    • 84924281435 scopus 로고    scopus 로고
    • SKI2162, an inhibitor of the TGF-beta type I receptor (ALK5), inhibits radiation-induced fibrosis in mice
    • Park JH, Ryu SH, Choi EK, Ahn SD, Park E, Choi KC, Lee SW. SKI2162, an inhibitor of the TGF-beta type I receptor (ALK5), inhibits radiation-induced fibrosis in mice. Oncotarget. 2015; 6:4171-4179. doi: 10.18632/oncotarget.2878.
    • (2015) Oncotarget. , vol.6 , pp. 4171-4179
    • Park, J.H.1    Ryu, S.H.2    Choi, E.K.3    Ahn, S.D.4    Park, E.5    Choi, K.C.6    Lee, S.W.7
  • 48
    • 0343417089 scopus 로고    scopus 로고
    • The p300/CBP family: integrating signals with transcription factors and chromatin
    • Shiama N. The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol. 1997; 7:230-236.
    • (1997) Trends Cell Biol. , vol.7 , pp. 230-236
    • Shiama, N.1
  • 52
    • 0021267048 scopus 로고
    • Leg contracture in mice: an assay of normal tissue response
    • Stone HB. Leg contracture in mice: an assay of normal tissue response. Int J Radiat Oncol Biol Phys. 1984; 10: 1053-1061.
    • (1984) Int J Radiat Oncol Biol Phys. , vol.10 , pp. 1053-1061
    • Stone, H.B.1
  • 54
    • 0344405718 scopus 로고    scopus 로고
    • Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1
    • Yoon HG, Chan DW, Huang ZQ, Li J, Fondell JD, Qin J, Wong J. Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1. The EMBO journal. 2003; 22:1336-1346.
    • (2003) The EMBO journal. , vol.22 , pp. 1336-1346
    • Yoon, H.G.1    Chan, D.W.2    Huang, Z.Q.3    Li, J.4    Fondell, J.D.5    Qin, J.6    Wong, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.