-
1
-
-
0042924438
-
Repression of c-Myc and inhibition of G1 exit in cells conditionally overexpressing p300 that is not dependent on its histone acetyltransferase activity
-
Baluchamy S, Rajabi HN, Thimmapaya R et al. (2003) Repression of c-Myc and inhibition of G1 exit in cells conditionally overexpressing p300 that is not dependent on its histone acetyltransferase activity. Proc Natl Acad Sci USA 100:9524-9
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9524-9529
-
-
Baluchamy, S.1
Rajabi, H.N.2
Thimmapaya, R.3
-
2
-
-
17244371148
-
Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta
-
Bhattacharyya S, Ghosh AK, Pannu J et al. (2005) Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta. Arthritis Rheum 52:1248-58
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1248-1258
-
-
Bhattacharyya, S.1
Ghosh, A.K.2
Pannu, J.3
-
3
-
-
80052715015
-
Egr-1 induces a profibrotic injury/repair gene program associated with systemic sclerosis
-
Bhattacharyya S, Sargent JL, Du P et al. (2011) Egr-1 induces a profibrotic injury/repair gene program associated with systemic sclerosis. PloS One 6:e23082
-
(2011)
PloS One
, vol.6
-
-
Bhattacharyya, S.1
Sargent, J.L.2
Du, P.3
-
4
-
-
33746374436
-
The early-immediate gene EGR-1 is induced by transforming growth factor-beta and mediates stimulation of collagen gene expression
-
Chen SJ, Ning H, Ishida W et al. (2006) The early-immediate gene EGR-1 is induced by transforming growth factor-beta and mediates stimulation of collagen gene expression. J Biol Chem 281:21183-97
-
(2006)
J Biol Chem
, vol.281
, pp. 21183-21197
-
-
Chen, S.J.1
Ning, H.2
Ishida, W.3
-
5
-
-
0032921867
-
Stimulation of type i collagen transcription in human skin fibroblasts by TGF-beta: Involvement of Smad 3
-
Chen SJ, Yuan W, Mori Y et al. (1999) Stimulation of type I collagen transcription in human skin fibroblasts by TGF-beta: involvement of Smad 3. J Invest Dermatol 112:49-57
-
(1999)
J Invest Dermatol
, vol.112
, pp. 49-57
-
-
Chen, S.J.1
Yuan, W.2
Mori, Y.3
-
6
-
-
0037036387
-
Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta
-
Czuwara-Ladykowska J, Sementchenko VI, Watson DK et al. (2002) Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta. J Biol Chem 277:20399-408
-
(2002)
J Biol Chem
, vol.277
, pp. 20399-20408
-
-
Czuwara-Ladykowska, J.1
Sementchenko, V.I.2
Watson, D.K.3
-
7
-
-
34748861551
-
Characterization of novel inhibitors of histone acetyltransferases
-
Eliseeva ED, Valkov V, Jung M et al. (2007) Characterization of novel inhibitors of histone acetyltransferases. Mol Cancer Ther 6:2391-8
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2391-2398
-
-
Eliseeva, E.D.1
Valkov, V.2
Jung, M.3
-
8
-
-
0036586090
-
Factors involved in the regulation of type i collagen gene expression: Implication in fibrosis
-
Ghosh AK (2002) Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med (Maywood) 227:301-14
-
(2002)
Exp Biol Med (Maywood)
, vol.227
, pp. 301-314
-
-
Ghosh, A.K.1
-
9
-
-
9144233017
-
The tumor suppressor p53 abrogates Smad-dependent collagen gene induction in mesenchymal cells
-
Ghosh AK, Bhattacharyya S, Varga J (2004) The tumor suppressor p53 abrogates Smad-dependent collagen gene induction in mesenchymal cells. J Biol Chem 279:47455-63
-
(2004)
J Biol Chem
, vol.279
, pp. 47455-47463
-
-
Ghosh, A.K.1
Bhattacharyya, S.2
Varga, J.3
-
10
-
-
70349331686
-
Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
-
Ghosh AK, Bhattacharyya S, Wei J et al. (2009) Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator. FASEB J 23: 2968-77
-
(2009)
FASEB J
, vol.23
, pp. 2968-2977
-
-
Ghosh, A.K.1
Bhattacharyya, S.2
Wei, J.3
-
11
-
-
33846548599
-
Trichostatin A blocks TGF-beta-induced collagen gene expression in skin fibroblasts: Involvement of Sp1
-
Ghosh AK, Mori Y, Dowling E et al. (2007) Trichostatin A blocks TGF-beta-induced collagen gene expression in skin fibroblasts: involvement of Sp1. Biochem Biophys Res Commun 354:420-6
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 420-426
-
-
Ghosh, A.K.1
Mori, Y.2
Dowling, E.3
-
12
-
-
35848951176
-
The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis
-
Ghosh AK, Varga J (2007) The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis. J Cell Physiol 213:663-71
-
(2007)
J Cell Physiol
, vol.213
, pp. 663-671
-
-
Ghosh, A.K.1
Varga, J.2
-
13
-
-
0035815696
-
Antagonistic regulation of type i collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactiva-tors
-
Ghosh AK, Yuan W, Mori Y et al. (2001) Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactiva-tors. J Biol Chem 276:11041-8
-
(2001)
J Biol Chem
, vol.276
, pp. 11041-11048
-
-
Ghosh, A.K.1
Yuan, W.2
Mori, Y.3
-
14
-
-
0034691764
-
Smad-dependent stimulation of type i collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators
-
Ghosh AK, Yuan W, Mori Y et al. (2000) Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators. Onco-gene 19:3546-55
-
(2000)
Onco-gene
, vol.19
, pp. 3546-3555
-
-
Ghosh, A.K.1
Yuan, W.2
Mori, Y.3
-
15
-
-
0032076229
-
Conjunction dysfunction: CBP/p300 in human disease
-
Giles RH, Peters DJ, Breuning MH (1998) Conjunction dysfunction: CBP/p300 in human disease. Trends Genet 14:178-83
-
(1998)
Trends Genet
, vol.14
, pp. 178-183
-
-
Giles, R.H.1
Peters, D.J.2
Breuning, M.H.3
-
16
-
-
0034234237
-
CBP/p300 in cell growth, transformation, and development
-
Goodman RH, Smolik S (2000) CBP/p300 in cell growth, transformation, and development. Genes Dev 14:1553-77
-
(2000)
Genes Dev
, vol.14
, pp. 1553-1577
-
-
Goodman, R.H.1
Smolik, S.2
-
17
-
-
31544442502
-
Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts
-
Ihn H, Yamane K, Asano Y et al. (2006) Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts. Rheumatology (Oxford) 45:157-65
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 157-165
-
-
Ihn, H.1
Yamane, K.2
Asano, Y.3
-
19
-
-
0036115749
-
The versatile functions of the transcriptional coactivators p300 and CBP and their roles in disease
-
Janknecht R (2002) The versatile functions of the transcriptional coactivators p300 and CBP and their roles in disease. Histol Histopathol 17:657-68
-
(2002)
Histol Histopathol
, vol.17
, pp. 657-668
-
-
Janknecht, R.1
-
20
-
-
77956629545
-
Histone deacetylase inhibition suppresses the transforming growth factor beta1-induced epithelial-to-mesenchymal transition in hepatocytes
-
Kaimori A, Potter JJ, Choti M et al. (2010) Histone deacetylase inhibition suppresses the transforming growth factor beta1-induced epithelial-to-mesenchymal transition in hepatocytes. Hepatology 52:1033-45
-
(2010)
Hepatology
, vol.52
, pp. 1033-1045
-
-
Kaimori, A.1
Potter, J.J.2
Choti, M.3
-
21
-
-
84867216946
-
Immunohis-tochemical evaluation of phosphorylated SMAD2/SMAD3 and the co-activator P300 in human glomerulonephritis: Correlation with renal injury
-
Kassimatis TI, Giannopoulou I, Koumoundourou D et al. (2006) Immunohis-tochemical evaluation of phosphorylated SMAD2/SMAD3 and the co-activator P300 in human glomerulonephritis: correlation with renal injury. J Cell Mol Med 10:908-21
-
(2006)
J Cell Mol Med
, vol.10
, pp. 908-921
-
-
Kassimatis, T.I.1
Giannopoulou, I.2
Koumoundourou, D.3
-
22
-
-
0032006563
-
P300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation
-
Kraus WL, Kadonaga JT (1998) p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation. Genes Dev 12:331-42
-
(1998)
Genes Dev
, vol.12
, pp. 331-342
-
-
Kraus, W.L.1
Kadonaga, J.T.2
-
23
-
-
78650782799
-
High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma
-
Li M, Luo RZ, Chen JW et al. (2011a) High expression of transcriptional coactivator p300 correlates with aggressive features and poor prognosis of hepatocellular carcinoma. J Transl Med 9:5
-
(2011)
J Transl Med
, vol.9
, pp. 5
-
-
Li, M.1
Luo, R.Z.2
Chen, J.W.3
-
24
-
-
79955449861
-
High expression of p300 has an unfavorable impact on survival in resectable esophageal squamous cell carcinoma
-
Li Y, Yang HX, Luo RZ et al. (2011b) High expression of p300 has an unfavorable impact on survival in resectable esophageal squamous cell carcinoma. Ann Thorac Surg 91:1531-8
-
(2011)
Ann Thorac Surg
, vol.91
, pp. 1531-1538
-
-
Li, Y.1
Yang, H.X.2
Luo, R.Z.3
-
25
-
-
84155184239
-
AMP-activated protein kinase inhibits TGF-beta-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300
-
Lim JY, Oh MA, Kim WH et al. (2012) AMP-activated protein kinase inhibits TGF-beta-induced fibrogenic responses of hepatic stellate cells by targeting transcriptional coactivator p300. J Cell Physiol 227:1081-9
-
(2012)
J Cell Physiol
, vol.227
, pp. 1081-1089
-
-
Lim, J.Y.1
Oh, M.A.2
Kim, W.H.3
-
26
-
-
1642357498
-
FIZZ1 stimulation of myofibroblast differentiation
-
Liu T, Dhanasekaran SM, Jin H et al. (2004) FIZZ1 stimulation of myofibroblast differentiation. Am J Pathol 164:1315-26
-
(2004)
Am J Pathol
, vol.164
, pp. 1315-1326
-
-
Liu, T.1
Dhanasekaran, S.M.2
Jin, H.3
-
27
-
-
0029022770
-
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
-
Petrij F, Giles RH, Dauwerse HG et al. (1995) Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature 376:348-51
-
(1995)
Nature
, vol.376
, pp. 348-351
-
-
Petrij, F.1
Giles, R.H.2
Dauwerse, H.G.3
-
28
-
-
20144386935
-
Genetic heterogeneity in Rubinstein-Taybi syndrome: Mutations in both the CBP and EP300 genes cause disease
-
Roelfsema JH, White SJ, Ariyurek Y et al. (2005) Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease. Am J Hum Genet 76:572-80
-
(2005)
Am J Hum Genet
, vol.76
, pp. 572-580
-
-
Roelfsema, J.H.1
White, S.J.2
Ariyurek, Y.3
-
29
-
-
33644946604
-
HATs and HDACs in neurodegeneration: A tale of disconcerted acetylation homeostasis
-
Saha RN, Pahan K (2006) HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death Differ 13:539-50
-
(2006)
Cell Death Differ
, vol.13
, pp. 539-550
-
-
Saha, R.N.1
Pahan, K.2
-
30
-
-
80052707789
-
Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines
-
Santer FR, Hoschele PP, Oh SJ et al. (2011) Inhibition of the acetyltransferases p300 and CBP reveals a targetable function for p300 in the survival and invasion pathways of prostate cancer cell lines. Mol Cancer Ther 10:1644-55
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1644-1655
-
-
Santer, F.R.1
Hoschele, P.P.2
Oh, S.J.3
-
31
-
-
0036064618
-
Scleroderma and Smads: Dysfunctional Smad family dynamics culminating in fibrosis
-
Varga J (2002) Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis. Arthritis Rheum 46:1703-13
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1703-1713
-
-
Varga, J.1
-
32
-
-
0035957953
-
CREB-binding protein and p300 in transcriptional regulation
-
Vo N, Goodman RH (2001) CREB-binding protein and p300 in transcriptional regulation. J Biol Chem 276:13505-8
-
(2001)
J Biol Chem
, vol.276
, pp. 13505-13508
-
-
Vo, N.1
Goodman, R.H.2
-
33
-
-
59649085854
-
Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma
-
Wu M, Melichian DS, Chang E et al. (2009) Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma. Am J Pathol 174:519-33
-
(2009)
Am J Pathol
, vol.174
, pp. 519-533
-
-
Wu, M.1
Melichian, D.S.2
Chang, E.3
-
34
-
-
80051687089
-
High expression of p300 in HCC predicts shortened overall survival in association with enhanced epithelial mesenchymal transition of HCC cells
-
Yokomizo C, Yamaguchi K, Itoh Y et al. (2011) High expression of p300 in HCC predicts shortened overall survival in association with enhanced epithelial mesenchymal transition of HCC cells. Cancer Lett 310:140-7
-
(2011)
Cancer Lett
, vol.310
, pp. 140-147
-
-
Yokomizo, C.1
Yamaguchi, K.2
Itoh, Y.3
-
35
-
-
3042801241
-
Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses
-
Yu J, de Belle I, Liang H et al. (2004) Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. Mol Cell 15:83-94
-
(2004)
Mol Cell
, vol.15
, pp. 83-94
-
-
Yu, J.1
De Belle, I.2
Liang, H.3
|