Fine-Tuning of CD8+ T Cell Mitochondrial Metabolism by the Respiratory Chain Repressor MCJ Dictates Protection to Influenza Virus

Immunity

Volumn 44, Issue 6, 2016, Pages 1299-1311

  Champagne, Devin P ^a   Hatle, Ketki M ^a   Fortner, Karen A ^a   D'Alessandro, Angelo ^b   Thornton, Tina M ^a   Yang, Rui ^a   Torralba, Daniel ^a   Tomás Cortázar, Julen ^c   Jun, Yong Woong ^d   Ahn, Kyo Han ^d   Hansen, Kirk C ^b   Haynes, Laura ^e   Anguita, Juan ^c,f   Rincon, Mercedes ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c CIC BIOGUNE   (Spain)

^d Pohang University of Science and Technology (POSTECH)   (South Korea)

^e UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^f BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHAPERONE; GAMMA INTERFERON; METHYLATION CONTROLLED J PROTEIN; UNCLASSIFIED DRUG; MCJ PROTEIN, MOUSE; MITOCHONDRIAL PROTEIN; MULTIENZYME COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL METABOLISM; CONTROLLED STUDY; CYTOKINE RELEASE; EFFECTOR CELL; GENE EXPRESSION; INFECTION PREVENTION; INFLUENZA; INFLUENZA VIRUS; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RESPIRATORY CHAIN; T LYMPHOCYTE ACTIVATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL RESPIRATION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; METABOLOME; MITOCHONDRION; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRUS INFECTION; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL RESPIRATION; CELLS, CULTURED; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; METABOLOME; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR CHAPERONES; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; OXIDATIVE PHOSPHORYLATION;

EID: 84971657476     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.02.018     Document Type: Article

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