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Angewandte Chemie - International Edition

Volumn 55, Issue 30, 2016, Pages 8661-8665

Mechanistic Studies on the Stereoselectivity of the Serotonin 5-HT1AReceptor

(5) Yuan, Shuguang a Peng, Qian b Palczewski, Krzysztof c Vogel, Horst a Filipek, Slawomir d

a EPFL (Switzerland)

b UNIVERSITY OF OXFORD (United Kingdom)

c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE (United States)

d UNIVERSITY OF WARSAW (Poland)

Author keywords

GPCRs; molecular dynamics simulations; proteins; stereoselectivity; water channels

Indexed keywords

PROTEINS; STEREOSELECTIVITY;

AMINO ACID RESIDUES; G PROTEIN COUPLED RECEPTORS; GPCRS; IDENTICAL STRUCTURES; MECHANISTIC STUDIES; MOLECULAR DYNAMICS SIMULATIONS; PHYSIOLOGICAL PROCESS; WATER CHANNELS;

MOLECULAR DYNAMICS;

APORPHINE DERIVATIVE; LIGAND; PROTEIN BINDING; SEROTONIN 1 AGONIST; SEROTONIN 1 ANTAGONIST; SEROTONIN 1A RECEPTOR; WATER;

BINDING SITE; CHEMISTRY; METABOLISM; MOLECULAR DYNAMICS; PROTEIN TERTIARY STRUCTURE; STEREOISOMERISM;

APORPHINES; BINDING SITES; LIGANDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN 5-HT1 RECEPTOR AGONISTS; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; STEREOISOMERISM; WATER;

EID: 84971623156 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201603766 Document Type: Article

Times cited : (23)

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