Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes

Stem Cells International

Volumn 2016, Issue , 2016, Pages

  Bruna, Flavia ^a   Contador, David ^a   Conget, Paulette ^a   Erranz, Benjamín ^a   Sossa, Claudia L ^b   Arango Rodríguez, Martha L ^b  

^a UNIVERSIDAD DEL DESARROLLO   (Chile)

^b UNIVERSIDAD AUTÓNOMA DE BUCARAMANGA   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; COLLAGEN FIBER; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; EPITHELIZATION; FEMALE; GRANULATION TISSUE; JUVENILE ANIMAL; MESENCHYMAL STEM CELL TRANSPLANTATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PARACRINE SIGNALING; SKIN APPENDAGE; TISSUE REGENERATION; WOUND; WOUND CLOSURE; WOUND HEALING;

EID: 84971596947     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2016/1461648     Document Type: Article

References (45)

1. A. I. Arno, S. Amini-Nik, P. H. Blit et al., "Human Wharton's jelly mesenchymal stem cells promote skin wound healing through paracrine signaling," Stem Cell Research and Therapy, vol. 5, no. 1, article 28, 2014.
2. J. Kato, H. Kamiya, T. Himeno et al., "Mesenchymal stem cells ameliorate impaired wound healing through enhancing keratinocyte functions in diabetic foot ulcerations on the plantar skin of rats," Journal of Diabetes and its Complications, vol. 28, no. 5, pp. 588-595, 2014.
3. A. S. de la Garza-Rodea, S. Knaän-Shanzer, and D. W. Van Bekkum, "Pressure ulcers: description of a new model and use of mesenchymal stem cells for repair," Dermatology, vol. 223, no. 3, pp. 266-284, 2011.
4. L. Liu, Y. Yu,Y. Hou et al., "Humanumbilical cordmesenchymal stem cells transplantation promotes cutaneous wound healing of severe burned rats," PLoS ONE, vol. 9, no. 2, Article ID e88348, 2014.
5. V. Falanga, S. Iwamoto, M. Chartier et al., "Autologous bone marrow-derivedculturedmesenchymal stemcellsdelivered ina fibrin spray accelerate healing in murine and human cutaneous wounds," Tissue Engineering, vol. 13, no. 6, pp. 1299-1312, 2007.
6. A. Bura, V. Planat-Benard, P. Bourin et al., "Phase I trial: the use of autologous cultured adipose-derived stroma/stemcells to treat patients with non-revascularizable critical limb ischemia," Cytotherapy, vol. 16, no. 2, pp. 245-257, 2014.
7. J. Vojtassak, L. Danisovic, M. Kubes et al., "Autologous biograft and mesenchymal stem cells in treatment of the diabetic foot," Neuro Endocrinology Letters, vol. 27, supplement 2, pp. 134-137, 2006.
8. E. Bey, M. Prat, P. Duhamel et al., "Emerging therapy for improving wound repair of severe radiation burns using local bone marrow-derived stem cell administrations," Wound Repair and Regeneration, vol. 18, no. 1, pp. 50-58, 2010.
9. C. Chavez-Munoz, K. T. Nguyen, W. Xu, S.-J. Hong, T. A. Mustoe, and R. D. Galiano, "Transdifferentiation of adiposederived stem cells into keratinocyte-like cells: engineering a stratified epidermis," PLoSONE, vol. 8, no. 12, Article IDe80587, 2013.
10. H. Ishikawa, J.-I. Jo, and Y. Tabata, "Liver anti-fibrosis therapy with mesenchymal stem cells secreting hepatocyte growth factor," Journal of Biomaterials Science, Polymer Edition, vol. 23, no. 18, pp. 2259-2272, 2012.
11. S. Schu, M. Nosov, L. O'Flynn et al., "Immunogenicity of allogeneic mesenchymal stem cells," Journal of Cellular and Molecular Medicine, vol. 16, no. 9, pp. 2094-2103, 2012.
12. C. Li, G. Wei, Q. Gu et al., "Donor age and cell passage affect osteogenic ability of rat bone marrow mesenchymal stem cells," Cell Biochemistry and Biophysics, vol. 72, no. 2, pp. 543-549, 2015.
13. L. W. Wu, Y.-L. Wang, J. M. Christensen et al., "Donor age negatively affects the immunoregulatory properties of both adipose and bone marrow derived mesenchymal stem cells," Transplant Immunology, vol. 30, no. 4, pp. 122-127, 2014.
14. B. Yao, S. Huang, D. Gao, J. Xie, N. Liu, and X. Fu, "Ageassociated changes in regenerative capabilities of mesenchymal stem cell: impact on chronic wounds repair," International Wound Journal, 2015.
15. L. Li, Y. Guo, H. Zhai et al., "Aging increases the susceptivity of MSCs to reactive oxygen species and impairs their therapeutic potency for myocardial infarction," PLoS ONE, vol. 9, no. 11, Article ID 0111850, 2014.
16. B. A. Scruggs, J. A. Semon, X. Zhang et al., "Age of the donor reduces the ability of human adipose-derived stem cells to alleviate symptoms in the experimental autoimmune encephalomyelitis mouse model," Stem Cells Translational Medicine, vol. 2, no. 10, pp. 797-807, 2013.
17. S. DeBarros, S. Dehez, E. Arnaud et al., "Aging-related decrease of human ASC angiogenic potential is reversed by hypoxia preconditioning through ROS production," MolecularTherapy, vol. 21, no. 2, pp. 399-408, 2013.
18. R. D. Galiano, J. Michaels V, M. Dobryansky, J. P. Levine, and G. C. Gurtner, "Quantitative and reproducible murine model of excisional wound healing," Wound Repair and Regeneration, vol. 12, no. 4, pp. 485-492, 2004.
19. H. A. Miot and G. Brianezi, "Morphometric analysis of dermal collagen by color clusters segmentation," Anais Brasileiros de Dermatologia, vol. 85, no. 3, pp. 361-364, 2010.
20. S. P. Bruder, N. Jaiswal, and S. E. Haynesworth, "Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation," Journal of Cellular Biochemistry, vol. 64, no. 2, pp. 278-294, 1997.
21. M. E. Nuttall, A. J. Patton, D. L. Olivera, D. P. Nadeau, and M. Gowen, "Human trabecular bone cells are able to express both osteoblastic and adipocytic phenotype: implications for osteopenic disorders," Journal of Bone and Mineral Research, vol. 13, no. 3, pp. 371-382, 1998.
22. T. D. Schmittgen and K. J. Livak, "Analyzing real-time PCR data by the comparative C method," Nature Protocols, vol. 3, pp. 1101-1108, 2008.
23. Z. Du, C. Wei, J. Yan et al., "Mesenchymal stem cells overexpressing C-X-C chemokine receptor type 4 improve early liver regeneration of small-for-size liver grafts," Liver Transplantation, vol. 19, no. 2, pp. 215-225, 2013.
24. A. Torres-Espín, J. Hernández, and X. Navarro, "Gene expression changes in the injured spinal cord following transplantation of mesenchymal stem cells or olfactory ensheathing cells," PLoS ONE, vol. 8, no. 10, Article IDe76141, 2013.
25. C. Seebach, D. Henrich, K. Wilhelm, J. H. Barker, and I. Marzi, "Endothelial progenitor cells improve directly and indirectly early vascularization of mesenchymal stem cell-driven bone regeneration in a critical bone defect in rats," Cell Transplantation, vol. 21, no. 8, pp. 1667-1677, 2012.
26. Y. Wu, L. Chen, P. G. Scott, and E. E. Tredget, "Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis," Stem Cells, vol. 25, no. 10, pp. 2648-2659, 2007.
27. H. S. Basiouny, N. M. Salama, Z. M. El Maadawi, and E. A. Farag, "Effect of bone marrow derived mesenchymal stem cells on healing of induced full-thickness skin wounds in albino rat," International Journal of Stem Cells, vol. 6, no. 1, pp. 12-25, 2013.
28. C.-Y. Fong, K. Tam, S. Cheyyatraivendran et al., "Human Wharton's jelly stem cells and its conditioned medium enhance healing of excisional and diabetic wounds," Journal of Cellular Biochemistry, vol. 115, no. 2, pp. 290-302, 2014.
29. Y. Wu, R. C. H. Zhao, and E. E. Tredget, "Concise review: bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration," Stem Cells, vol. 28, no. 5, pp. 905-915, 2010.
30. Y. Xu, S. Huang, K. Ma, X. Fu, W. Han, and Z. Sheng, "Promising new potential for mesenchymal stem cells derived from human umbilical cord Wharton's jelly: sweat gland celllike differentiative capacity," Journal of Tissue Engineering and Regenerative Medicine, vol. 6, no. 8, pp. 645-654, 2012.
31. J. Zhang, J. Guan, X. Niu et al., "Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis," Journal of Translational Medicine, vol. 13, article 49, 2015.
32. S. J. Hong, S.-X. Jia, P. Xie et al., "Topically delivered adipose derived stem cells show an activated-fibroblast phenotype and enhance granulation tissue formation in skin wounds," PLoS ONE, vol. 8, no. 1,Article ID e55640, 2013.
33. A. T. Badillo, R. A. Redden, L. Zhang, E. J. Doolin, and K. W. Liechty, "Treatment of diabetic wounds with fetal murine mesenchymal stromal cells enhances wound closure," Cell and Tissue Research, vol. 329, no. 2, pp. 301-311, 2007.
34. M. S. Choudhery, M. Badowski, A. Muise, J. Pierce, and D. T. Harris, "Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation," Journal of Translational Medicine, vol. 12, article 8, 2014.
35. M. A. Baxter, R. F. Wynn, S. N. Jowitt, J. E. Wraith, L. J. Fairbairn, and I. Bellantuono, "Studyof telomere length reveals rapidaging of human marrow stromal cells following in vitro expansion," Stem Cells, vol. 22, no. 5, pp. 675-682, 2004.
36. O. Katsara, L. G. Mahaira, E. G. Iliopoulou et al., "Effects of donor age, gender, and in vitro cellular aging on the phenotypic, functional, and molecular characteristics of mouse bone marrow-derived mesenchymal stem cells," Stem Cells and Development, vol. 20, no. 9, pp. 1549-1561, 2011.
37. R. J. Bergman, D. Gazit, A. J. Kahn, H. Gruber, S. Mcdougall, and T. J. Hahn, "Age-related changes in osteogenic stem cells in mice," Journal of Bone and Mineral Research, vol. 11, no. 5, pp. 568-577, 1996.
38. F. Z. Asumda and P. B. Chase, "Age-related changes in rat bonemarrow mesenchymal stem cell plasticity," BMC Cell Biology, vol. 12, article 44, 2011.
39. S. V. Tokalov, S. Grüner, S. Schindler, G. Wolf, M. Baumann, and N. Abolmaali, "Age-related changes in the frequency of mesenchymal stem cells in the bone marrow of rats," Stem Cells and Development, vol. 16, no. 3, pp. 439-446, 2007.
40. H. Zheng, J. A. Martin, Y. Duwayri, G. Falcon, and J. A. Buckwalter, "Impact of aging on rat bone marrow-derived stem cell chondrogenesis," Journals of Gerontology-Series A Biological Sciences and Medical Sciences, vol. 62, no. 2, pp. 136-148, 2007.
41. S. Barrientos, O. Stojadinovic, M. S. Golinko, H. Brem, and M. Tomic-Canic, "Growth factors and cytokines in wound healing,"Wound Repair and Regeneration, vol. 16,no. 5, pp. 585-601, 2008.
42. A. Wilson, L. A. Shehadeh, H. Yu, and K. A. Webster, "Agerelated molecular genetic changes of murine bone marrow mesenchymal stem cells," BMC Genomics, vol. 11, article 229, 2010.
43. R. Freter, M. Osawa, and S.-I. Nishikawa, "Adult stem cells exhibit global suppression of RNA polymerase II serine-2 phosphorylation," Stem Cells, vol. 28, no. 9, pp. 1571-1580, 2010.
44. K. Gala, A. Burdzínska, M. Idziak, J. Makula, and L. Paczek, "Characterization of bone-marrow-derived rat mesenchymal stem cells depending on donor age," Cell Biology International, vol. 35, no. 10, pp. 1055-1062, 2011.
45. S. Jiang, H. Kh Haider, R. P. H. Ahmed, N. M. Idris, A. Salim, and M. Ashraf, "Transcriptional profiling of young and old mesenchymal stem cells in response to oxygen deprivation and reparability of the infarcted myocardium," Journal of Molecular and Cellular Cardiology, vol. 44, no. 3, pp. 582-596, 2008.