Donor age negatively affects the immunoregulatory properties of both adipose and bone marrow derived mesenchymal stem cells

Transplant Immunology

Volumn 30, Issue 4, 2014, Pages 122-127

  Wu, Lehao W ^a,b   Wang, Yen Ling ^a,c   Christensen, Joani M ^a   Khalifian, Saami ^a   Schneeberger, Stefan ^a,d   Raimondi, Giorgio ^a   Cooney, Damon S ^a   Lee, W P Andrew ^a   Brandacher, Gerald ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Adipose tissue; Age; Bone marrow; Immunoregulation; Mesenchymal stem cells

Indexed keywords

BETA1 INTEGRIN; CD11 ANTIGEN; CD45 ANTIGEN; THY 1 ANTIGEN; PTPRC PROTEIN, RAT;

ADIPOSE MESENCHYMAL STEM CELL; AGE; ALLOIMMUNITY; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL EXPANSION; CELL GROWTH; CELL ISOLATION; CELL KINETICS; CELL STRUCTURE; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; DONOR AGE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GRAFT RECIPIENT; IMMUNOGENICITY; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MESENCHYMAL STEM CELL; MIXED LYMPHOCYTE REACTION; NONHUMAN; PRIORITY JOURNAL; RAT; ADIPOSE TISSUE; AGING; ANIMAL; BONE MARROW CELL; CELL PROLIFERATION; COCULTURE; CYTOLOGY; DONOR; GENETICS; IMMUNOLOGY; LEWIS RAT; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; MIXED LYMPHOCYTE CULTURE;

ADIPOSE TISSUE; AGE FACTORS; AGING; ANIMALS; ANTIGENS, CD11; ANTIGENS, CD29; ANTIGENS, CD45; ANTIGENS, THY-1; BONE MARROW CELLS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; COCULTURE TECHNIQUES; LYMPHOCYTE CULTURE TEST, MIXED; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; RATS; RATS, INBRED LEW; TISSUE DONORS;

EID: 84900032595     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2014.03.001     Document Type: Article

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