Activated brain mast cells contribute to postoperative cognitive dysfunction by evoking microglia activation and neuronal apoptosis

Journal of Neuroinflammation

Volumn 13, Issue 1, 2016, Pages

  Zhang, Xiang ^a   Dong, Hongquan ^a   Li, Nana ^a   Zhang, Susu ^a   Sun, Jie ^a   Zhang, Shu ^a   Qian, Yanning ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Cromolyn; Mast cells; Microglia activation; Neuroinflammation; Neuronal apoptosis; Postoperative cognitive dysfunction

Indexed keywords

INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL INTERACTION; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MALE; MAST CELL; MAST CELL DEGRANULATION; MEMORY DISORDER; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NONHUMAN; POSTOPERATIVE COGNITIVE DYSFUNCTION; RAT; SIGNAL TRANSDUCTION; ANIMAL; BRAIN; CELL CULTURE; CELL LINE; COGNITIVE DYSFUNCTION; IMMUNOLOGY; METABOLISM; NERVE CELL; NEWBORN; PHYSIOLOGY; POSTOPERATIVE COMPLICATION; PREGNANCY; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BRAIN; CELL LINE; CELLS, CULTURED; COGNITIVE DYSFUNCTION; FEMALE; MALE; MAST CELLS; MICE; MICROGLIA; NEURONS; POSTOPERATIVE COMPLICATIONS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84971570856     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-016-0592-9     Document Type: Article

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