Evidence for the involvement of neuropeptide y in the antidepressant effect of imipramine in type 2 diabetes

Brain Research

Volumn 1646, Issue , 2016, Pages 1-11

  Nakhate, Kartik T ^a   Yedke, Sadanand U ^b   Bharne, Ashish P ^b   Subhedar, Nishikant K ^c   Kokare, Dadasaheb M ^b  

^a RUNGTA COLLEGE OF PHARMACEUTICAL SCIENCES AND RESEARCH   (India)

^b RTM NAGPUR UNIVERSITY   (India)

^c INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; IMIPRAMINE; NALPHA (DIPHENYLACETYL) N (4 HYDROXYBENZYL) DEXTRO ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y [31 LEUCINE 34 PROLINE]; ARGININE; GLUCOSE BLOOD LEVEL; NEUROPEPTIDE Y RECEPTOR; NPY1R PROTEIN, MOUSE; STREPTOZOCIN; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; AMYGDALA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG POTENTIATION; GLUCOSE BLOOD LEVEL; IMMOBILITY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INSULIN RESISTANCE; LIPID DIET; LOCOMOTION; MALE; MOOD DISORDER; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEUS ACCUMBENS SHELL; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; STRIA TERMINALIS; TAIL SUSPENSION TEST; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CENTRAL NUCLEUS (AMYGDALA); COMPLICATION; DISEASE MODEL; DRUG EFFECTS; METABOLISM; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; PATHOPHYSIOLOGY; PHYSIOLOGY; SEPTUM NUCLEUS;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ARGININE; BLOOD GLUCOSE; CENTRAL AMYGDALOID NUCLEUS; DEPRESSION; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; IMIPRAMINE; MALE; MICE; MOTOR ACTIVITY; NEUROPEPTIDE Y; NUCLEUS ACCUMBENS; RECEPTORS, NEUROPEPTIDE Y; SEPTAL NUCLEI; STREPTOZOCIN;

EID: 84971475264     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2016.05.035     Document Type: Article

References (66)

1. S. Andrikopoulos, A.R. Blair, N. Deluca, B.C. Fam, and J. Proietto Evaluating the glucose tolerance test in mice Am. J. Physiol. Endocrinol. Metab. 295 2008 E1323 E1332
2. M.S. Antunes, J.R. Ruff, D. de Oliveira Espinosa, M.B. Piegas, M.L. de Brito, K.A. Rocha, M.G. de Gomes, A.T. Goes, L.C. Souza, F. Donato, S.P. Boeira, and C.R. Jesse Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice Horm. Behav. 73 2015 56 63
3. R.A. Baker, M. Herkenham, and L.S. Brady Effects of long-term treatment with antidepressant drugs on proopiomelanocortin and neuropeptide Y mRNA expression in the hypothalamic arcuate nucleus of rats J. Neuroendocrinol. 8 1996 337 343
4. S.M. Bhisikar, D.M. Kokare, K.T. Nakhate, C.T. Chopde, and N.K. Subhedar Tolerance to ethanol sedation and withdrawal hyper-excitability is mediated by neuropeptide Y Y1 and Y5 receptors Life Sci. 85 2009 765 772
5. A.A. Bhorkar, M.P. Dandekar, K.T. Nakhate, N.K. Subhedar, and D.M. Kokare Involvement of the central melanocortin system in the effects of caffeine on anxiety-like behavior in mice Life Sci. 95 2014 72 80
6. W.W. Blessing, P.R. Howe, T.H. Joh, J.R. Oliver, and J.O. Willoughby Distribution of tyrosine hydroxyla se and neuropeptide Y-like immunoreactive neurons in rabbit medulla oblongata, with attention to colocalization studies, presumptive adrenaline-synthesizing perikarya, and vagal preganglionic cells J. Comp. Neurol. 248 1986 285 300
7. L. Caberlotto, K. Fuxe, D.H. Overstreet, P. Gerrard, and Y.L. Hurd Alterations in neuropeptide Y and Y1 receptor mRNA expression in brains from an animal model of depression: region specific adaptation after fluoxetine treatment Mol. Brain Res. 59 1998 58 65
8. L. Caberlotto, P. Jimenez, D.H. Overstreet, Y.L. Hurd, A.A. Mathe, and K. Fuxe Alterations in neuropeptide Y levels and Y1 binding sites in the Flinders Sensitive Line rats, a genetic animal model of depression Neurosci. Lett. 265 1999 191 194
9. J.F. Cryan, C. Mombereau, and A. Vassout The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice Neurosci. Biobehav. Rev. 29 2005 571 625
10. M.P. Dandekar, K.T. Nakhate, D.M. Kokare, and N.K. Subhedar Effect of nicotine on feeding and body weight in rats: involvement of cocaine- and amphetamine-regulated transcript peptide Behav. Brain Res. 219 2011 31 38
11. M.P. Dandekar, K.T. Nakhate, D.M. Kokare, and N.K. Subhedar Involvement of CART in estradiol induced anorexia Physiol. Behav. 105 2012 460 469
12. M. de Groot, R. Anderson, K.E. Freedland, R.E. Clouse, and P.J. Lustman Association of depression and diabetes complications: a meta analysis Psychosom. Med. 63 2001 619 630
13. G.S. Deo, M.P. Dandekar, M.A. Upadhya, D.M. Kokare, and N.K. Subhedar Neuropeptide Y Y1 receptors in the central nucleus of amygdala mediate the anxiolytic-like effect of allopregnanolone in mice: behavioral and immunocytochemical evidences Brain Res. 1318 2010 77 86
14. S.J. Desai, C.D. Borkar, K.T. Nakhate, N.K. Subhedar, and D.M. Kokare Neuropeptide Y attenuates anxiety- and depression-like effects of cholecystokinin-4 in mice Neuroscience 277 2014 818 830
15. H.N. Doods, H.A. Wieland, W. Engel, W. Eberlein, K.D. Willim, M. Entzeroth, W. Wienen, and K. Rudolf BIBP 3226, the first selective neuropeptide Y1 receptor antagonist: a review of its pharmacological properties Regul. Pept. 65 1996 71 77
16. B.J. Everitt, T. Hokfelt, L. Terenius, K. Tatemoto, V. Mutt, and M. Goldstein Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catechol amines in the central nervous system of the rat Neuroscience 11 1984 443 462
17. X. Fioramonti, S. Contié, Z. Song, V.H. Routh, A. Lorsignol, and L. Pénicaud Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opiomelanocortin networks? Diabetes 56 2007 1219 1227
18. P.K. Ganguly Neuropeptide Y level in paraventricular nucleus of experimental diabetic rats: correlation with sympathetic activity and body weight Int. J. Gen. MEd 3 2010 321 325
19. A. Gjerris, E. Widerlöv, L. Werdelin, and R. Ekman Cerebrospinal fluid concentrations of neuropeptide Y in depressed patients and in controls J. Psychiatry Neurosci. 17 1992 23 27
20. S.N. Goyal, D.M. Kokare, C.T. Chopde, and N.K. Subhedar Alpha-melanocyte stimulating hormone antagonizes antidepressant-like effect of neuropeptide Y in Porsolt's test in rats Pharmacol. Biochem. Behav. 85 2006 369 377
21. S.N. Goyal, N.M. Reddy, K.R. Patil, K.T. Nakhate, S. Ojha, C.R. Patil, and Y.O. Agrawal Challenges and issues with streptozotocin-induced diabetes - a clinically relevant animal model to understand the diabetes pathogenesis and evaluate therapeutics Chem. Biol. Interact. 244 2016 49 63
22. S.N. Goyal, M.A. Upadhya, D.M. Kokare, S.M. Bhisikar, and N.K. Subhedar Neuropeptide Y modulates the antidepressant activity of imipramine in olfactory bulbectomized rats: involvement of NPY Y1 receptors Brain Res. 1266 2009 45 53
23. D. Gupta, Y. Kurhe, and M. Radhakrishnan Antidepressant effects of insulin in streptozotocin induced diabetic mice: modulation of brain serotonin system Physiol. Behav. 129 2014 73 78
24. M. Heilig, C. Wahlestedt, R. Ekman, and E. Widerlov Antidepressant drugs increase the concentration of neuropeptide Y (NPY)-like immunoreactivity in the rat brain Eur. J. Pharmacol. 147 1988 465 467
25. A. Inui, M. Okita, T. Inoue, N. Sakatani, H. Morioka, K. Shii, K. Yokono, N. Mizuno, and S. Baba Characterization of peptide YY receptors in the brain Endocrinology 124 1989 402 409
26. H. Ishida, Y. Shirayama, M. Iwata, and R. Kawahara Subchronic treatment with imipramine ameliorates the decreased number in neuropeptide Y-positive cells in the hippocampus of learned helplessness rats Brain Res. 1046 2005 239 243
27. M.S. Islam Fasting blood glucose and diagnosis of type 2 diabetes Diabetes Res. Clin. Pract. 91 2011 e26
28. T. Iype, S.K. Shaji, A. Balakrishnan, D. Charles, A.A. Varghese, and T.P. Antony Cognition in Type 2 diabetes: association with vascular risk factors, complications of diabetes and depression Ann. Indian. Acad. Neurol. 12 2009 25 27
29. N. Joseph, B. Unnikrishnan, Y.P. RaghavendraBabu, M.S. Kotian, and M. Nelliyanil Proportion of depression and its determinants among type 2 diabetes mellitus patients in various tertiary care hospitals in Mangalore city of South India Indian J. Endocrinol. Metab. 17 2013 681 688
30. S.P. Kamdi, K.T. Nakhate, M.P. Dandekar, D.M. Kokare, and N.K. Subhedar Participation of corticotropin-releasing factor type 2 receptors in the acute, chronic and withdrawal actions of nicotine associated with feeding behavior in rats Appetite 53 2009 354 362
31. J.H. Kim, J.H. Pan, H.T. Cho, and Y.J. Kim Black ginseng extract counteracts streptozotocin-induced diabetes in mice PLoS One 11 2016 e0146843
32. Y. Kitamura, H. Araki, T. Nagatani, K. Takao, K. Shibata, and Y. Gomita Influence of imipramine on the duration of immobility in chronic forced-swim -stressed rats Acta Med. Okayama 58 2004 271 274
33. D.M. Kokare, G.P. Shelkar, C.D. Borkar, K.T. Nakhate, and N.K. Subhedar A simple and inexpensive method to fabricate a cannula system for intracranial injections in rats and mice J. Pharmacol. Toxicol. Methods 64 2011 246 250
34. V. Krishnan, and E.J. Nestler The molecular neurobiology of depression Nature 455 2008 894 902
35. D.D. Luo, S.C. An, and X. Zhang Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress Brain Res. Bull. 77 2008 8 12
36. P.J. Lustman, R.J. Anderson, K.E. Freedland, M. de Groot, R.M. Carney, and R.E. Clouse Depression and poor glycemic control: a meta-analytic review of the literature Diabetes Care 23 2000 934 942
37. J.C. Martel, A. Fournier, S. St-Pierre, Y. Dumont, M. Forest, and R. Quirion Comparative structural requirements of brain neuropeptide Y binding sites and vas deferens neuropeptide Y receptors Mol. Pharmacol. 38 1990 494 502
38. 125I]Bolton-Hunter neuropeptide Y binding sites in the forebrain of various mammalian species Brain Res. 419 1987 403 407
39. H. Meena, K.T. Nakhate, D.M. Kokare, and N.K. Subhedar GABAA receptors in nucleus accumbens shell mediate the hyperphagia and weight gain following haloperidol treatment in rats Life Sci. 84 2009 156 163
40. S. Muroya, T. Yada, S. Shioda, and M. Takigawa Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y Neurosci. Lett. 264 1999 113 116
41. K.T. Nakhate, M.P. Dandekar, D.M. Kokare, and N.K. Subhedar Involvement of neuropeptide Y Y(1) receptors in the acute, chronic and withdrawal effects of nicotine on feeding and body weight in rats Eur. J. Pharmacol. 609 2009 78 87
42. K.T. Nakhate, D.M. Kokare, P.S. Singru, and N.K. Subhedar Central regulation of feeding behavior during social isolation of rat: evidence for the role of endogenous CART system Int. J. Obes. 35 2011 773 784
43. K.T. Nakhate, D.M. Kokare, P.S. Singru, A.G. Taksande, S.D. Kotwal, and N.K. Subhedar Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis Pharmacol. Biochem. Behav. 97 2010 340 349
44. K.T. Nakhate, N.K. Subhedar, A.P. Bharne, P.S. Singru, and D.M. Kokare Involvement of cocaine- and amphetamine-regulated transcript peptide in the hyperphagic and body weight promoting effects of allopregnanolone in rats Brain Res. 1532 2013 44 55
45. D.H. Overstreet The Flinders sensitive line rats: a genetic animal model of depression Neurosci. Biobehav. Rev. 17 1993 51 68
46. D.H. Overstreet, O. Pucilowski, A.H. Rezvani, and D.S. Janowsky Administration of antidepressants, diazepam and psychomotor stimulants further confirms the utility of Flinders Sensitive Line rats as an animal model of depression Psychopharmacology 121 1995 27 37
47. S. Ozsoy, O. Olguner Eker, and U. Abdulrezzak The effects of antidepressants on neuropeptide Y in patients with depression and anxiety Pharmacopsychiatry 49 2016 26 31
48. G. Paxinos, and K.B. Franklin The Mouse Brain in Stereotaxic Co-ordinates 2001 Academic Press California
49. R.J. Rangani, M.A. Upadhya, K.T. Nakhate, D.M. Kokare, and N.K. Subhedar Nicotine evoked improvement in learning and memory is mediated through NPY Y1 receptors in rat model of Alzheimer's disease Peptides 33 2012 317 328
50. J.P. Redrobe, Y. Dumont, A. Fournier, G.B. Baker, and R. Quirion Role of serotonin (5-HT) in the antidepressant-like properties of neuropeptide Y (NPY) in the mouse forced swim test Peptides 26 2005 1394 1400
51. A.M. Rosier, G.A. Orban, and F. Vandesande Regional distribution of binding sites for neuropeptide Y in cat and monkey visual cortex determined by in vitro receptor autoradiography J. Comp. Neurol. 293 1990 486 498
52. K. Rudolf, W. Eberlein, W. Engel, H.A. Wieland, K.D. Willim, M. Entzeroth, W. Wienen, A.G. Beck-Sickinger, and H.N. Doods The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226 Eur. J. Pharmacol. 271 1994 11 13
53. B.M. Shah, G.V. Gupchup, M.E. Borrego, D.W. Raisch, and K.K. Knapp Depressive symptoms in patients with type 2 diabetes in the ambulatory care setting: opportunities to improve outcomes in the course of routine care J. Am. Pharm. Assoc. 48 2008 737 743
54. J.W. Sohn Network of hypothalamic neurons that control appetite BMB Rep. 48 2015 229 233
55. C. Song, B. Earley, and B.E. Leonard The effects of central administration of neuropeptide Y on behavior, neurotransmitter, and immune functions in the olfactory bulbectomized rat model of depression Brain Behav. Immun. 10 1996 1 16
56. K. Srinivasan, B. Viswanad, L. Asrat, C.L. Kaul, and P. Ramarao Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening Pharmacol. Res. 52 2005 313 320
57. L. Steru, R. Chermat, B. Thierry, J.A. Mico, A. Lenegre, M. Steru, P. Simon, and R.D. Porsolt The automated tail suspension test: a computerized device which differentiates psychotropic drugs Prog. Neuropsychopharmacol. Biol. Psychiatry 11 1987 659 671
58. L. Steru, R. Chermat, B. Thierry, and P. Simon The tail suspension test: a new method for screening antidepressants in mice Psychopharmacology 85 1985 367 370
59. B.G. Taksande, N.R. Kotagale, K.T. Nakhate, P.D. Mali, D.M. Kokare, K. Hirani, N.K. Subhedar, C.T. Chopde, and R.R. Ugale Agmatine in the hypothalamic paraventricular nucleus stimulates feeding in rats: involvement of neuropeptide Y Br. J. Pharmacol. 164 2011 704 718
60. M.A. Upadhya, K.T. Nakhate, D.M. Kokare, U. Singh, P.S. Singru, and N.K. Subhedar CART peptide in the nucleus accumbens shell acts downstream to dopamine and mediates the reward and reinforcement actions of morphine Neuropharmacology 62 2012 1823 1833
61. M.A. Upadhya, K.T. Nakhate, D.M. Kokare, P.S. Singru, and N.K. Subhedar Cocaine- and amphetamine-regulated transcript peptide increases spatial learning and memory in rats Life Sci. 88 2011 322 334
62. P.S. Widdowson, G.A. Ordway, and A.E. Halaris Reduced neuropeptide Y concentrations in suicide brain J. Neurochem. 59 1992 73 80
63. Widerlov, E., Wahlestedt, C., Hakanson, R., Ekman, R., 1986. Altered brain neuropeptide function in psychiatric illness-with special emphasis on NPY and CRF in major depression. In: Proceedings of C. I. N. P. 15th Congress. Clin. Neuropharmacol., vol. 9, pp. 572-574
64. R.D. Wilson, and M.S. Islam Fructose-fed streptozotocin-injected rat: an alternative model for type 2 diabetes Pharmacol. Rep. 64 2012 129 139
65. N. Yokoi, M. Hoshino, S. Hidaka, E. Yoshida, M. Beppu, R. Hoshikawa, K. Sudo, A. Kawada, S. Takagi, and S. Seino A novel rat model of type 2 diabetes: the Zucker fatty diabetes mellitus ZFDM rat J. Diabetes Res. 2013 2013 103731
66. M.I. Zafar, C. Hu, D. Liu, R.A. Shafqat, and F. Gao Insulin detemir causes lesser weight gain in comparison to insulin glargine: role on hypothalamic NPY and galanin J. Diabetes Res. 2014 2014 458104