Lunasin suppresses the migration and invasion of breast cancer cells by inhibiting matrix metalloproteinase-2/-9 via the FAK/Akt/ERK and NF-κB signaling pathways

Oncology Reports

Volumn 36, Issue 1, 2016, Pages 253-262

  Jiang, Qianqian ^a,b   Pan, Yu ^c   Cheng, Yupeng ^b   Li, Huiling ^b   Liu, Dandan ^b   Li, Hui ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^c HEILONGJIANG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Breast cancer; FAK Akt ERK; Lunasin; Metastasis; NF B

Indexed keywords

ALPHAVBETA5 INTEGRIN; ANTINEOPLASTIC AGENT; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUNASIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN RECEPTOR; ARGINYL-GLYCYL-ASPARTIC ACID; FOCAL ADHESION KINASE 1; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; OLIGOPEPTIDE; PEPTIDE; PTK2 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; METASTASIS; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR INVASION; BREAST NEOPLASMS; CELL MOTION; DOWN REGULATION; DRUG EFFECTS; FEMALE; MCF-7 CELL LINE; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; FOCAL ADHESION KINASE 1; HUMANS; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MCF-7 CELLS; NEOPLASM INVASIVENESS; NF-KAPPA B; OLIGOPEPTIDES; PEPTIDES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84971382118     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2016.4798     Document Type: Article

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