-
1
-
-
84856584192
-
The dramatic increase in total knee replacement utilization rates in the United States cannot be fully explained by growth in population size and the obesity epidemic
-
Losina E, Thornhill TS, Rome BN, Wright J, Katz JN., The dramatic increase in total knee replacement utilization rates in the United States cannot be fully explained by growth in population size and the obesity epidemic. J Bone Joint Surg Am 2012; 94: 201-7.
-
(2012)
J Bone Joint Surg Am
, vol.94
, pp. 201-207
-
-
Losina, E.1
Thornhill, T.S.2
Rome, B.N.3
Wright, J.4
Katz, J.N.5
-
2
-
-
84905591268
-
Bone-cartilage interface crosstalk in osteoarthritis: Potential pathways and future therapeutic strategies
-
Yuan XL, Meng HY, Wang YC, Peng J, Guo QY, Wang AY, et al., Bone-cartilage interface crosstalk in osteoarthritis: potential pathways and future therapeutic strategies. Osteoarthritis Cartilage 2014; 22: 1077-89.
-
(2014)
Osteoarthritis Cartilage
, vol.22
, pp. 1077-1089
-
-
Yuan, X.L.1
Meng, H.Y.2
Wang, Y.C.3
Peng, J.4
Guo, Q.Y.5
Wang, A.Y.6
-
3
-
-
84908381697
-
Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage
-
Jeffries MA, Donica M, Baker LW, Stevenson ME, Annan AC, Humphrey MB, et al., Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage. Arthritis Rheumatol 2014; 66: 2804-15.
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 2804-2815
-
-
Jeffries, M.A.1
Donica, M.2
Baker, L.W.3
Stevenson, M.E.4
Annan, A.C.5
Humphrey, M.B.6
-
4
-
-
84904667534
-
Characterization of the cartilage DNA methylome in knee and hip osteoarthritis
-
Rushton MD, Reynard LN, Barter MJ, Refaie R, Rankin KS, Young DA, et al., Characterization of the cartilage DNA methylome in knee and hip osteoarthritis. Arthritis Rheumatol 2014; 66: 2450-60.
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 2450-2460
-
-
Rushton, M.D.1
Reynard, L.N.2
Barter, M.J.3
Refaie, R.4
Rankin, K.S.5
Young, D.A.6
-
5
-
-
84911447416
-
Epigenetic differences in human cartilage between mild and severe OA
-
Moazedi-Fuerst FC, Hofner M, Gruber G, Weinhaeusel A, Stradner MH, Angerer H, et al., Epigenetic differences in human cartilage between mild and severe OA. J Orthop Res 2014; 32: 1636-45.
-
(2014)
J Orthop Res
, vol.32
, pp. 1636-1645
-
-
Moazedi-Fuerst, F.C.1
Hofner, M.2
Gruber, G.3
Weinhaeusel, A.4
Stradner, M.H.5
Angerer, H.6
-
6
-
-
84895419805
-
Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients
-
Fernandez-Tajes J, Soto-Hermida A, Vazquez-Mosquera ME, Cortes-Pereira E, Mosquera A, Fernandez-Moreno M, et al., Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients. Ann Rheum Dis 2014; 73: 668-77.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 668-677
-
-
Fernandez-Tajes, J.1
Soto-Hermida, A.2
Vazquez-Mosquera, M.E.3
Cortes-Pereira, E.4
Mosquera, A.5
Fernandez-Moreno, M.6
-
7
-
-
84889689979
-
NFATc1 and NFATc2 repress spontaneous osteoarthritis
-
Greenblatt MB, Ritter SY, Wright J, Tsang K, Hu D, Glimcher LH, et al., NFATc1 and NFATc2 repress spontaneous osteoarthritis. Proc Natl Acad Sci U S A 2013; 110: 19914-9.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 19914-19919
-
-
Greenblatt, M.B.1
Ritter, S.Y.2
Wright, J.3
Tsang, K.4
Hu, D.5
Glimcher, L.H.6
-
8
-
-
38649091333
-
A navigator for human genome epidemiology
-
Yu W, Gwinn M, Clyne M, Yesupriya A, Khoury MJ., A navigator for human genome epidemiology. Nat Genet 2008; 40: 124-5.
-
(2008)
Nat Genet
, vol.40
, pp. 124-125
-
-
Yu, W.1
Gwinn, M.2
Clyne, M.3
Yesupriya, A.4
Khoury, M.J.5
-
9
-
-
84900392015
-
Bioenergetics and gene silencing approaches for unraveling nucleotide recognition by the human EIF2C2/Ago2 PAZ domain
-
Kandeel M, Al-Taher A, Nakashima R, Sakaguchi T, Kandeel A, Nagaya Y, et al., Bioenergetics and gene silencing approaches for unraveling nucleotide recognition by the human EIF2C2/Ago2 PAZ domain. PLoS One 2014; 9: e94538.
-
(2014)
PLoS One
, vol.9
, pp. e94538
-
-
Kandeel, M.1
Al-Taher, A.2
Nakashima, R.3
Sakaguchi, T.4
Kandeel, A.5
Nagaya, Y.6
-
10
-
-
84926613424
-
Signature of circulating microRNAs in osteoarthritis
-
Beyer C, Zampetaki A, Lin NY, Kleyer A, Perricone C, Iagnocco A, et al., Signature of circulating microRNAs in osteoarthritis. Ann Rheum Dis 2015; 74: e18.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. e18
-
-
Beyer, C.1
Zampetaki, A.2
Lin, N.Y.3
Kleyer, A.4
Perricone, C.5
Iagnocco, A.6
-
13
-
-
44149084243
-
The induction of endochondral bone formation by transforming growth factor-β3: Experimental studies in the non-human primate Papio ursinus
-
Ripamonti U, Ramoshebi LN, Teare J, Renton L, Ferretti C., The induction of endochondral bone formation by transforming growth factor-β3: experimental studies in the non-human primate Papio ursinus. J Cell Mol Med 2008; 12: 1029-48.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 1029-1048
-
-
Ripamonti, U.1
Ramoshebi, L.N.2
Teare, J.3
Renton, L.4
Ferretti, C.5
-
14
-
-
30344448285
-
Transforming growth factor-β3 promotes mesenchymal cell proliferation and angiogenesis mediated by the enhancement of cyclin D1, Flk-1, and CD31 gene expression during CL/Fr mouse lip fusion
-
Muraoka N, Shum L, Fukumoto S, Nomura T, Ohishi M, Nonaka K., Transforming growth factor-β3 promotes mesenchymal cell proliferation and angiogenesis mediated by the enhancement of cyclin D1, Flk-1, and CD31 gene expression during CL/Fr mouse lip fusion. Birth Defects Res A Clin Mol Teratol 2005; 73: 956-65.
-
(2005)
Birth Defects Res A Clin Mol Teratol
, vol.73
, pp. 956-965
-
-
Muraoka, N.1
Shum, L.2
Fukumoto, S.3
Nomura, T.4
Ohishi, M.5
Nonaka, K.6
-
15
-
-
77955565285
-
Regeneration of the articular surface of the rabbit synovial joint by cell homing: A proof of concept study
-
Lee CH, Cook JL, Mendelson A, Moioli EK, Yao H, Mao JJ., Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet 2010; 376: 440-8.
-
(2010)
Lancet
, vol.376
, pp. 440-448
-
-
Lee, C.H.1
Cook, J.L.2
Mendelson, A.3
Moioli, E.K.4
Yao, H.5
Mao, J.J.6
-
16
-
-
23844515714
-
NFAT and Osterix cooperatively regulate bone formation
-
Koga T, Matsui Y, Asagiri M, Kodama T, de Crombrugghe B, Nakashima K, et al., NFAT and Osterix cooperatively regulate bone formation. Nat Med 2005; 11: 880-5.
-
(2005)
Nat Med
, vol.11
, pp. 880-885
-
-
Koga, T.1
Matsui, Y.2
Asagiri, M.3
Kodama, T.4
De Crombrugghe, B.5
Nakashima, K.6
-
17
-
-
84924732460
-
Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: A novel mechanism of human osteoarthritis cartilage degeneration
-
Cao K, Wei L, Zhang Z, Guo L, Zhang C, Li Y, et al., Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of human osteoarthritis cartilage degeneration. Arthritis Res Ther 2014; 16: 491.
-
(2014)
Arthritis Res Ther
, vol.16
, pp. 491
-
-
Cao, K.1
Wei, L.2
Zhang, Z.3
Guo, L.4
Zhang, C.5
Li, Y.6
-
18
-
-
84924245230
-
Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis
-
Lu J, Sun Y, Ge Q, Teng H, Jiang Q., Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis. BMC Musculoskelet Disord 2014; 15: 438.
-
(2014)
BMC Musculoskelet Disord
, vol.15
, pp. 438
-
-
Lu, J.1
Sun, Y.2
Ge, Q.3
Teng, H.4
Jiang, Q.5
-
19
-
-
84891586536
-
A coregulatory network of NR2F1 and microRNA-140
-
Chiang DY, Cuthbertson DW, Ruiz FR, Li N, Pereira FA., A coregulatory network of NR2F1 and microRNA-140. PLoS One 2013; 8: e83358.
-
(2013)
PLoS One
, vol.8
, pp. e83358
-
-
Chiang, D.Y.1
Cuthbertson, D.W.2
Ruiz, F.R.3
Li, N.4
Pereira, F.A.5
-
20
-
-
1642506297
-
Down-regulation of Hox A7 is required for cell adhesion and migration on fibronectin during early HL-60 monocytic differentiation
-
Leroy P, Berto F, Bourget I, Rossi B., Down-regulation of Hox A7 is required for cell adhesion and migration on fibronectin during early HL-60 monocytic differentiation. J Leukoc Biol 2004; 75: 680-8.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 680-688
-
-
Leroy, P.1
Berto, F.2
Bourget, I.3
Rossi, B.4
-
21
-
-
58949102957
-
Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation
-
Cheung CL, Chan BY, Chan V, Ikegawa S, Kou I, Ngai H, et al., Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. Hum Mol Genet 2009; 18: 679-87.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 679-687
-
-
Cheung, C.L.1
Chan, B.Y.2
Chan, V.3
Ikegawa, S.4
Kou, I.5
Ngai, H.6
-
22
-
-
43449128415
-
Early lymphocyte activation in the synovial microenvironment in patients with osteoarthritis: Comparison with rheumatoid arthritis patients and healthy controls
-
Rollin R, Marco F, Jover JA, Garcia-Asenjo JA, Rodriguez L, Lopez-Duran L, et al., Early lymphocyte activation in the synovial microenvironment in patients with osteoarthritis: comparison with rheumatoid arthritis patients and healthy controls. Rheumatol Int 2008; 28: 757-64.
-
(2008)
Rheumatol Int
, vol.28
, pp. 757-764
-
-
Rollin, R.1
Marco, F.2
Jover, J.A.3
Garcia-Asenjo, J.A.4
Rodriguez, L.5
Lopez-Duran, L.6
-
23
-
-
33947264796
-
Expression of Hoxa2 in cells entering chondrogenesis impairs overall cartilage development
-
Massip L, Ectors F, Deprez P, Maleki M, Behets C, Lengele B, et al., Expression of Hoxa2 in cells entering chondrogenesis impairs overall cartilage development. Differentiation 2007; 75: 256-67.
-
(2007)
Differentiation
, vol.75
, pp. 256-267
-
-
Massip, L.1
Ectors, F.2
Deprez, P.3
Maleki, M.4
Behets, C.5
Lengele, B.6
-
24
-
-
84885902332
-
Molecular study of a Hoxa2 gain-of-function in chondrogenesis: A model of idiopathic proportionate short stature
-
Deprez PM, Nichane MG, Lengele BG, Rezsohazy R, Nyssen-Behets C., Molecular study of a Hoxa2 gain-of-function in chondrogenesis: a model of idiopathic proportionate short stature. Int J Mol Sci 2013; 14: 20386-98.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 20386-20398
-
-
Deprez, P.M.1
Nichane, M.G.2
Lengele, B.G.3
Rezsohazy, R.4
Nyssen-Behets, C.5
-
25
-
-
37149053758
-
Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor β-induced osteophytes: Limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation
-
Blaney Davidson EN, Vitters EL, van Beuningen HM, van de Loo FA, van den Berg WB, van der Kraan PM., Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor β-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation. Arthritis Rheum 2007; 56: 4065-73.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 4065-4073
-
-
Blaney Davidson, E.N.1
Vitters, E.L.2
Van Beuningen, H.M.3
Van De Loo, F.A.4
Van Den Berg, W.B.5
Van Der Kraan, P.M.6
-
26
-
-
84880297184
-
Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis
-
Zhen G, Wen C, Jia X, Li Y, Crane JL, Mears SC, et al., Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritis. Nat Med 2013; 19: 704-12.
-
(2013)
Nat Med
, vol.19
, pp. 704-712
-
-
Zhen, G.1
Wen, C.2
Jia, X.3
Li, Y.4
Crane, J.L.5
Mears, S.C.6
-
27
-
-
85006962800
-
Pro-inflammatory IL-β and/or TNFα up-regulate matrix metalloproteases-1 and -3 mRNA in chondrocyte subpopulations potentially pathogenic in osteoarthritis: In situ hybridization studies on a single cell level
-
E-pub ahead of print.
-
Kunisch E, Kinne RW, Alsalameh RJ, Alsalameh S., Pro-inflammatory IL-β and/or TNFα up-regulate matrix metalloproteases-1 and -3 mRNA in chondrocyte subpopulations potentially pathogenic in osteoarthritis: in situ hybridization studies on a single cell level. Int J Rheum Dis 2014. E-pub ahead of print.
-
(2014)
Int J Rheum Dis
-
-
Kunisch, E.1
Kinne, R.W.2
Alsalameh, R.J.3
Alsalameh, S.4
-
28
-
-
0029997374
-
Tumor necrosis factor-α (TNF-α) in canine osteoarthritis: Immunolocalization of TNF-α, stromelysin and TNF receptors in canine osteoarthritic cartilage
-
Kammermann JR, Kincaid SA, Rumph PF, Baird DK, Visco DM., Tumor necrosis factor-α (TNF-α) in canine osteoarthritis: immunolocalization of TNF-α, stromelysin and TNF receptors in canine osteoarthritic cartilage. Osteoarthritis Cartilage 1996; 4: 23-34.
-
(1996)
Osteoarthritis Cartilage
, vol.4
, pp. 23-34
-
-
Kammermann, J.R.1
Kincaid, S.A.2
Rumph, P.F.3
Baird, D.K.4
Visco, D.M.5
-
29
-
-
0035808458
-
Tumor necrosis factor-α (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways
-
Zhang YH, Heulsmann A, Tondravi MM, Mukherjee A, Abu-Amer Y., Tumor necrosis factor-α (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. J Biol Chem 2001; 276: 563-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 563-568
-
-
Zhang, Y.H.1
Heulsmann, A.2
Tondravi, M.M.3
Mukherjee, A.4
Abu-Amer, Y.5
-
30
-
-
69949117163
-
Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: The MOST Study. A longitudinal multicentre study of knee osteoarthritis
-
Roemer FW, Guermazi A, Javaid MK, Lynch JA, Niu J, Zhang Y, et al., Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis. Ann Rheum Dis 2009; 68: 1461-5.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1461-1465
-
-
Roemer, F.W.1
Guermazi, A.2
Javaid, M.K.3
Lynch, J.A.4
Niu, J.5
Zhang, Y.6
-
31
-
-
70450202838
-
Detection of pain-related molecules in the subchondral bone of osteoarthritic knees
-
Ogino S, Sasho T, Nakagawa K, Suzuki M, Yamaguchi S, Higashi M, et al., Detection of pain-related molecules in the subchondral bone of osteoarthritic knees. Clin Rheumatol 2009; 28: 1395-402.
-
(2009)
Clin Rheumatol
, vol.28
, pp. 1395-1402
-
-
Ogino, S.1
Sasho, T.2
Nakagawa, K.3
Suzuki, M.4
Yamaguchi, S.5
Higashi, M.6
-
32
-
-
84928809478
-
Meta-analysis of tumor necrosis factor α -308 polymorphism and knee osteoarthritis risk
-
Kou S, Wu Y., Meta-analysis of tumor necrosis factor α -308 polymorphism and knee osteoarthritis risk. BMC Musculoskelet Disord 2014; 15: 373.
-
(2014)
BMC Musculoskelet Disord
, vol.15
, pp. 373
-
-
Kou, S.1
Wu, Y.2
-
33
-
-
84956580614
-
RNAi silencing of IL-1β and TNF-α in the treatment of post-traumatic arthritis in rabbits
-
Tang Q, Hao L, Peng Y, Zheng Y, Sun K, Cai F, et al., RNAi silencing of IL-1β and TNF-α in the treatment of post-traumatic arthritis in rabbits. Chem Biol Drug Des 2015; 86: 1466-70.
-
(2015)
Chem Biol Drug des
, vol.86
, pp. 1466-1470
-
-
Tang, Q.1
Hao, L.2
Peng, Y.3
Zheng, Y.4
Sun, K.5
Cai, F.6
-
34
-
-
34250203639
-
A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands
-
Magnano MD, Chakravarty EF, Broudy C, Chung L, Kelman A, Hillygus J, et al., A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands. J Rheumatol 2007; 34: 1323-7.
-
(2007)
J Rheumatol
, vol.34
, pp. 1323-1327
-
-
Magnano, M.D.1
Chakravarty, E.F.2
Broudy, C.3
Chung, L.4
Kelman, A.5
Hillygus, J.6
-
35
-
-
84925542702
-
Adalimumab in patients with hand osteoarthritis refractory to analgesics and NSAIDs: A randomised, multicentre, double-blind, placebo-controlled trial
-
Chevalier X, Ravaud P, Maheu E, Baron G, Rialland A, Vergnaud P, et al., Adalimumab in patients with hand osteoarthritis refractory to analgesics and NSAIDs: a randomised, multicentre, double-blind, placebo-controlled trial. Ann Rheum Dis 2015; 74: 1697-705.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 1697-1705
-
-
Chevalier, X.1
Ravaud, P.2
Maheu, E.3
Baron, G.4
Rialland, A.5
Vergnaud, P.6
-
36
-
-
84860918903
-
Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: A double blind, randomised trial on structure modification
-
Verbruggen G, Wittoek R, Vander Cruyssen B, Elewaut D., Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification. Ann Rheum Dis 2012; 71: 891-8.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 891-898
-
-
Verbruggen, G.1
Wittoek, R.2
Vander Cruyssen, B.3
Elewaut, D.4
-
37
-
-
55249118159
-
Mitogen-activated protein kinases as therapeutic targets in osteoarthritis
-
Loeser RF, Erickson EA, Long DL., Mitogen-activated protein kinases as therapeutic targets in osteoarthritis. Curr Opin Rheumatol 2008; 20: 581-6.
-
(2008)
Curr Opin Rheumatol
, vol.20
, pp. 581-586
-
-
Loeser, R.F.1
Erickson, E.A.2
Long, D.L.3
-
38
-
-
84891700757
-
Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment
-
Prasadam I, Mao X, Shi W, Crawford R, Xiao Y., Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment. J Mol Med 2013; 91: 369-80.
-
(2013)
J Mol Med
, vol.91
, pp. 369-380
-
-
Prasadam, I.1
Mao, X.2
Shi, W.3
Crawford, R.4
Xiao, Y.5
-
39
-
-
33745019918
-
Elevated serum levels of soluble interleukin-4 receptor in osteoarthritis
-
Silvestri T, Pulsatelli L, Dolzani P, Facchini A, Meliconi R., Elevated serum levels of soluble interleukin-4 receptor in osteoarthritis. Osteoarthritis Cartilage 2006; 14: 717-9.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 717-719
-
-
Silvestri, T.1
Pulsatelli, L.2
Dolzani, P.3
Facchini, A.4
Meliconi, R.5
-
40
-
-
85022178172
-
IL4-10 synerkine for the treatment of osteoarthritis
-
Steen-Louws C, Pustjens MF, Mastbergen SC, Hack CE, van Roon J, Lafeber F., IL4-10 synerkine for the treatment of osteoarthritis. Ann Rheum Dis 2015; 74: A36-A37.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. A36-A37
-
-
Steen-Louws, C.1
Pustjens, M.F.2
Mastbergen, S.C.3
Hack, C.E.4
Van Roon, J.5
Lafeber, F.6
-
41
-
-
84908289349
-
Women with osteoarthritis have elevated synovial fluid levels of insulin-like growth factor (IGF)-1 and IGF-binding protein-3
-
Hooshmand S, Juma S, Khalil DA, Shamloufard P, Arjmandi BH., Women with osteoarthritis have elevated synovial fluid levels of insulin-like growth factor (IGF)-1 and IGF-binding protein-3. J Immunoassay Immunochem 2015; 36: 284-94.
-
(2015)
J Immunoassay Immunochem
, vol.36
, pp. 284-294
-
-
Hooshmand, S.1
Juma, S.2
Khalil, D.A.3
Shamloufard, P.4
Arjmandi, B.H.5
-
42
-
-
0031918202
-
IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis
-
Martel-Pelletier J, Di Battista JA, Lajeunesse D, Pelletier JP., IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis. Inflamm Res 1998; 47: 90-100.
-
(1998)
Inflamm Res
, vol.47
, pp. 90-100
-
-
Martel-Pelletier, J.1
Di Battista, J.A.2
Lajeunesse, D.3
Pelletier, J.P.4
-
43
-
-
70450274965
-
Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-kinase-Akt and MEK-ERK MAPK signaling pathways
-
Yin W, Park JI, Loeser RF., Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-kinase-Akt and MEK-ERK MAPK signaling pathways. J Biol Chem 2009; 284: 31972-81.
-
(2009)
J Biol Chem
, vol.284
, pp. 31972-31981
-
-
Yin, W.1
Park, J.I.2
Loeser, R.F.3
-
44
-
-
77649149361
-
Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family
-
Chen HC, Kraus VB, Li YJ, Nelson S, Haynes C, Johnson J, et al., Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family. Arthritis Rheum 2010; 62: 781-90.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 781-790
-
-
Chen, H.C.1
Kraus, V.B.2
Li, Y.J.3
Nelson, S.4
Haynes, C.5
Johnson, J.6
-
45
-
-
20944450269
-
Haplotypes of the low-density lipoprotein receptor-related protein 5 (LRP5) gene: Are they a risk factor in osteoarthritis?
-
Smith AJ, Gidley J, Sandy JR, Perry MJ, Elson CJ, Kirwan JR, et al., Haplotypes of the low-density lipoprotein receptor-related protein 5 (LRP5) gene: are they a risk factor in osteoarthritis? Osteoarthritis Cartilage 2005; 13: 608-13.
-
(2005)
Osteoarthritis Cartilage
, vol.13
, pp. 608-613
-
-
Smith, A.J.1
Gidley, J.2
Sandy, J.R.3
Perry, M.J.4
Elson, C.J.5
Kirwan, J.R.6
-
46
-
-
84882492575
-
The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: A Mendelian randomisation study
-
Panoutsopoulou K, Metrustry S, Doherty SA, Laslett LL, Maciewicz RA, Hart DJ, et al., The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study. Ann Rheum Dis 2014; 73: 2082-6.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 2082-2086
-
-
Panoutsopoulou, K.1
Metrustry, S.2
Doherty, S.A.3
Laslett, L.L.4
MacIewicz, R.A.5
Hart, D.J.6
-
47
-
-
84857503338
-
Genome wide analysis reveals association of a FTO gene variant with epigenetic changes
-
Almen MS, Jacobsson JA, Moschonis G, Benedict C, Chrousos GP, Fredriksson R, et al., Genome wide analysis reveals association of a FTO gene variant with epigenetic changes. Genomics 2012; 99: 132-7.
-
(2012)
Genomics
, vol.99
, pp. 132-137
-
-
Almen, M.S.1
Jacobsson, J.A.2
Moschonis, G.3
Benedict, C.4
Chrousos, G.P.5
Fredriksson, R.6
-
48
-
-
32444433647
-
Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women
-
Valdes AM, van Oene M, Hart DJ, Surdulescu GL, Loughlin J, Doherty M, et al., Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women. Arthritis Rheum 2006; 54: 533-9.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 533-539
-
-
Valdes, A.M.1
Van Oene, M.2
Hart, D.J.3
Surdulescu, G.L.4
Loughlin, J.5
Doherty, M.6
-
49
-
-
85018425270
-
Differential DNA methylation and reduced expression of critical transcription factors in human OA cartilage
-
Alvarez-Garcia O, Fisch KM, Akagi R, Su AI, Lotz MK., Differential DNA methylation and reduced expression of critical transcription factors in human OA cartilage. Osteoarthritis Cartilage 2015; 23: A72 -A3.
-
(2015)
Osteoarthritis Cartilage
, vol.23
, pp. A3-A72
-
-
Alvarez-Garcia, O.1
Fisch, K.M.2
Akagi, R.3
Su, A.I.4
Lotz, M.K.5
-
50
-
-
84871770976
-
Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis
-
Delgado-Calle J, Fernandez AF, Sainz J, Zarrabeitia MT, Sanudo C, García-Renedo R, et al., Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis. Arthritis Rheum 2013; 65: 197-205.
-
(2013)
Arthritis Rheum
, vol.65
, pp. 197-205
-
-
Delgado-Calle, J.1
Fernandez, A.F.2
Sainz, J.3
Zarrabeitia, M.T.4
Sanudo, C.5
García-Renedo, R.6
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