The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: A mendelian randomisation study

Annals of the Rheumatic Diseases

Volumn 73, Issue 12, 2014, Pages 2082-2086

  Panoutsopoulou, Kalliope ^a   Metrustry, Sarah ^b   Doherty, Sally A ^c   Laslett, Laura L ^d   Maciewicz, Rose A ^e   Hart, Deborah J ^b   Zhang, Weiya ^c   Muir, Kenneth R ^f,g   Wheeler, Margaret ^c   Cooper, Cyrus ^h,i   Spector, Tim D ^b   Cicuttini, Flavia M ^j   Jones, Graeme ^d   Arden, Nigel K ^h,i   Doherty, Michael ^c   Zeggini, Eleftheria ^a   Valdes, Ana M ^b,c  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^d UNIVERSITY OF TASMANIA   (Australia)

^e ASTRAZENECA R AND D   (Sweden)

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

^g UNIVERSITY OF WARWICK   (United Kingdom)

^h UNIVERSITY OF OXFORD   (United Kingdom)

ⁱ UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^j MONASH UNIVERSITY   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

FTO PROTEIN, HUMAN; PROTEIN;

AGED; BODY MASS; CASE CONTROL STUDY; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; HIP OSTEOARTHRITIS; HUMAN; KNEE OSTEOARTHRITIS; MALE; MENDELIAN RANDOMIZATION ANALYSIS; MIDDLE AGED; OBESITY; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; BODY MASS INDEX; CASE-CONTROL STUDIES; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MENDELIAN RANDOMIZATION ANALYSIS; MIDDLE AGED; OBESITY; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE; OVERWEIGHT; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS;

EID: 84882492575     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2013-203772     Document Type: Article

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