메뉴 건너뛰기




Volumn 83, Issue 1, 2017, Pages 54-62

Oleuropein aglycone and polyphenols from olive mill waste water ameliorate cognitive deficits and neuropathology

Author keywords

Alzheimer's disease; amyloid plaques; authophagy; memory function; oleuropein aglycone; olive polyphenols

Indexed keywords

ACTEOSIDE; AGLYCONE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; HYDROXYTHYROSOL; NEUROPROTECTIVE AGENT; OLE DI ALDEHYDE; OLEUROPEIN; OLEUROPEIN AGLYCONE; OLIVE OIL; POLYPHENOL DERIVATIVE; THYROSOL; UNCLASSIFIED DRUG; AMYLOID BETA-PROTEIN (1-42); AMYLOID PRECURSOR PROTEIN; IRIDOID; PEPTIDE FRAGMENT; POLYPHENOL;

EID: 84971247385     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12993     Document Type: Review
Times cited : (69)

References (46)
  • 1
    • 1442264828 scopus 로고    scopus 로고
    • Take five–BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation
    • Haass C. Take five–BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation. EMBO J 2004; 23: 483–8.
    • (2004) EMBO J , vol.23 , pp. 483-488
    • Haass, C.1
  • 2
    • 0001181116 scopus 로고    scopus 로고
    • Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics
    • Selkoe DJ, Schenk D. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol 2003; 43: 545–84.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 545-584
    • Selkoe, D.J.1    Schenk, D.2
  • 3
    • 84889665489 scopus 로고    scopus 로고
    • Amyloid beta-protein oligomers and Alzheimer's disease
    • Hayden EY, Teplow DB. Amyloid beta-protein oligomers and Alzheimer's disease. Alzheimers Res Ther 2013; 5: 60.
    • (2013) Alzheimers Res Ther , vol.5 , pp. 60
    • Hayden, E.Y.1    Teplow, D.B.2
  • 4
    • 84884769320 scopus 로고
    • Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases
    • Cheng B, Gong H, Xiao H, Petersen RB, Zheng L, Huang K. Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases. Biochim Biophys Acta 1830; 2013: 4860–71.
    • (1830) Biochim Biophys Acta , vol.2013 , pp. 4860-4871
    • Cheng, B.1    Gong, H.2    Xiao, H.3    Petersen, R.B.4    Zheng, L.5    Huang, K.6
  • 5
    • 0036135139 scopus 로고    scopus 로고
    • A possible role for pi-stacking in the self-assembly of amyloid fibrils
    • Gazit E. A possible role for pi-stacking in the self-assembly of amyloid fibrils. FASEB J 2002; 16: 77–83.
    • (2002) FASEB J , vol.16 , pp. 77-83
    • Gazit, E.1
  • 7
    • 78751560834 scopus 로고    scopus 로고
    • Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils
    • Giorgetti S, Raimondi S, Pagano K, Relini A, Bucciantini M, Corazza A, et al. Effect of tetracyclines on the dynamics of formation and destructuration of beta2-microglobulin amyloid fibrils. J Biol Chem 2011; 286: 2121–31.
    • (2011) J Biol Chem , vol.286 , pp. 2121-2131
    • Giorgetti, S.1    Raimondi, S.2    Pagano, K.3    Relini, A.4    Bucciantini, M.5    Corazza, A.6
  • 8
    • 84907998488 scopus 로고    scopus 로고
    • Beneficial properties of natural phenols: highlight on protection against pathological conditions associated with amyloid aggregation
    • Stefani M, Rigacci S. Beneficial properties of natural phenols: highlight on protection against pathological conditions associated with amyloid aggregation. Biofactors 2014; 40: 482–93.
    • (2014) Biofactors , vol.40 , pp. 482-493
    • Stefani, M.1    Rigacci, S.2
  • 9
    • 79953837275 scopus 로고    scopus 로고
    • A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes
    • Ahmad E, Ahmad A, Singh S, Arshad M, Khan AH, Khan RH. A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes. Biochimie 2011; 93: 793–805.
    • (2011) Biochimie , vol.93 , pp. 793-805
    • Ahmad, E.1    Ahmad, A.2    Singh, S.3    Arshad, M.4    Khan, A.H.5    Khan, R.H.6
  • 11
    • 79952499466 scopus 로고    scopus 로고
    • Mediterranean diet and magnetic resonance imaging-assessed cerebrovascular disease
    • Scarmeas N, Luchsinger JA, Stern Y, Gu Y, He J, DeCarli C, et al. Mediterranean diet and magnetic resonance imaging-assessed cerebrovascular disease. Ann Neurol 2011; 69: 257–68.
    • (2011) Ann Neurol , vol.69 , pp. 257-268
    • Scarmeas, N.1    Luchsinger, J.A.2    Stern, Y.3    Gu, Y.4    He, J.5    DeCarli, C.6
  • 13
    • 84872872264 scopus 로고    scopus 로고
    • Potential benefits of adherence to the Mediterranean diet on cognitive health
    • Feart C, Samieri C, Alles B, Barberger-Gateau P. Potential benefits of adherence to the Mediterranean diet on cognitive health. Proc Nutr Soc 2013; 72: 140–52.
    • (2013) Proc Nutr Soc , vol.72 , pp. 140-152
    • Feart, C.1    Samieri, C.2    Alles, B.3    Barberger-Gateau, P.4
  • 14
    • 82055197196 scopus 로고    scopus 로고
    • Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon
    • Rigacci S, Guidotti V, Bucciantini M, Nichino D, Relini A, Berti A, et al. Abeta(1-42) aggregates into non-toxic amyloid assemblies in the presence of the natural polyphenol oleuropein aglycon. Curr Alzheimer Res 2011; 8: 841–52.
    • (2011) Curr Alzheimer Res , vol.8 , pp. 841-852
    • Rigacci, S.1    Guidotti, V.2    Bucciantini, M.3    Nichino, D.4    Relini, A.5    Berti, A.6
  • 15
    • 84877120241 scopus 로고    scopus 로고
    • Olive-oil-derived oleocanthal enhances beta-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies
    • Abuznait AH, Qosa H, Busnena BA, El Sayed KA, Kaddoumi A. Olive-oil-derived oleocanthal enhances beta-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies. ACS Chem Neurosci 2013; 4: 973–82.
    • (2013) ACS Chem Neurosci , vol.4 , pp. 973-982
    • Abuznait, A.H.1    Qosa, H.2    Busnena, B.A.3    El Sayed, K.A.4    Kaddoumi, A.5
  • 16
    • 84867153806 scopus 로고    scopus 로고
    • Modulation of tau protein fibrillization by oleocanthal
    • Monti MC, Margarucci L, Riccio R, Casapullo A. Modulation of tau protein fibrillization by oleocanthal. J Nat Prod 2012; 75: 1584–8.
    • (2012) J Nat Prod , vol.75 , pp. 1584-1588
    • Monti, M.C.1    Margarucci, L.2    Riccio, R.3    Casapullo, A.4
  • 17
    • 79951931265 scopus 로고    scopus 로고
    • Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population
    • Tangney CC, Kwasny MJ, Li H, Wilson RS, Evans DA, Morris MC. Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population. Am J Clin Nutr 2011; 93: 601–7.
    • (2011) Am J Clin Nutr , vol.93 , pp. 601-607
    • Tangney, C.C.1    Kwasny, M.J.2    Li, H.3    Wilson, R.S.4    Evans, D.A.5    Morris, M.C.6
  • 18
    • 68849101447 scopus 로고    scopus 로고
    • Adherence to a Mediterranean diet, cognitive decline, and risk of dementia
    • Feart C, Samieri C, Rondeau V, Amieva H, Portet F, Dartigues JF, et al. Adherence to a Mediterranean diet, cognitive decline, and risk of dementia. JAMA 2009; 302: 638–48.
    • (2009) JAMA , vol.302 , pp. 638-648
    • Feart, C.1    Samieri, C.2    Rondeau, V.3    Amieva, H.4    Portet, F.5    Dartigues, J.F.6
  • 19
    • 77953613891 scopus 로고    scopus 로고
    • Effects of dietary extra-virgin olive oil on behaviour and brain biochemical parameters in ageing rats
    • Pitozzi V, Jacomelli M, Zaid M, Luceri C, Bigagli E, Lodovici M, et al. Effects of dietary extra-virgin olive oil on behaviour and brain biochemical parameters in ageing rats. Br J Nutr 2010; 103: 1674–83.
    • (2010) Br J Nutr , vol.103 , pp. 1674-1683
    • Pitozzi, V.1    Jacomelli, M.2    Zaid, M.3    Luceri, C.4    Bigagli, E.5    Lodovici, M.6
  • 20
    • 84860205395 scopus 로고    scopus 로고
    • Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk
    • Valls-Pedret C, Lamuela-Raventos RM, Medina-Remon A, Quintana M, Corella D, Pintó X, et al. Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk. J Alzheimers Dis 2012; 29: 773–82.
    • (2012) J Alzheimers Dis , vol.29 , pp. 773-782
    • Valls-Pedret, C.1    Lamuela-Raventos, R.M.2    Medina-Remon, A.3    Quintana, M.4    Corella, D.5    Pintó, X.6
  • 21
    • 70349241517 scopus 로고    scopus 로고
    • Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal
    • Pitt J, Roth W, Lacor P, Smith AB 3rd, Blankenship M, Velasco P, et al. Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicol Appl Pharmacol 2009; 240: 189–97.
    • (2009) Toxicol Appl Pharmacol , vol.240 , pp. 189-197
    • Pitt, J.1    Roth, W.2    Lacor, P.3    Smith, A.B.4    Blankenship, M.5    Velasco, P.6
  • 22
    • 7444221782 scopus 로고    scopus 로고
    • Health and sensory properties of virgin olive oil hydrophilic phenols: agronomic and technological aspects of production that affect their occurrence in the oil
    • Servili M, Selvaggini R, Esposto S, Taticchi A, Montedoro G, Morozzi G. Health and sensory properties of virgin olive oil hydrophilic phenols: agronomic and technological aspects of production that affect their occurrence in the oil. J Chromatogr A 2004; 1054: 113–27.
    • (2004) J Chromatogr A , vol.1054 , pp. 113-127
    • Servili, M.1    Selvaggini, R.2    Esposto, S.3    Taticchi, A.4    Montedoro, G.5    Morozzi, G.6
  • 25
    • 84874778760 scopus 로고    scopus 로고
    • Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ 42 by reducing plaque load and motor deficit
    • Diomede L, Rigacci S, Romeo M, Stefani M, Salmona M. Oleuropein aglycone protects transgenic C. elegans strains expressing Aβ 42 by reducing plaque load and motor deficit. PLoS One 2013; 8: e58893.
    • (2013) PLoS One , vol.8
    • Diomede, L.1    Rigacci, S.2    Romeo, M.3    Stefani, M.4    Salmona, M.5
  • 26
    • 84881327671 scopus 로고    scopus 로고
    • The polyphenol oleuropein aglycone protects TgCRND8 mice against Aβ plaque pathology
    • Grossi C, Rigacci S, Ambrosini S, Ed Dami T, Luccarini I, Traini C, et al. The polyphenol oleuropein aglycone protects TgCRND8 mice against Aβ plaque pathology. PLoS One 2013; 8: e71702.
    • (2013) PLoS One , vol.8
    • Grossi, C.1    Rigacci, S.2    Ambrosini, S.3    Ed Dami, T.4    Luccarini, I.5    Traini, C.6
  • 27
    • 84922840562 scopus 로고    scopus 로고
    • Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ss toxicity: biochemical, epigenetic and functional correlates
    • Luccarini I, Grossi C, Rigacci S, Coppi E, Pugliese AM, Pantano D, et al. Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ss toxicity: biochemical, epigenetic and functional correlates. Neurobiol Aging 2015; 36: 648–63.
    • (2015) Neurobiol Aging , vol.36 , pp. 648-663
    • Luccarini, I.1    Grossi, C.2    Rigacci, S.3    Coppi, E.4    Pugliese, A.M.5    Pantano, D.6
  • 28
    • 0035877756 scopus 로고    scopus 로고
    • Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
    • Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, Pearson J, et al. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 2001; 276: 21562–70.
    • (2001) J Biol Chem , vol.276 , pp. 21562-21570
    • Chishti, M.A.1    Yang, D.S.2    Janus, C.3    Phinney, A.L.4    Horne, P.5    Pearson, J.6
  • 29
    • 84930040836 scopus 로고    scopus 로고
    • Evaporation-condensation of olive mill wastewater: evaluation of condensate treatability through SBR and constructed Wetlands
    • Masi F, Bresciani R, Munz G, Lubello C. Evaporation-condensation of olive mill wastewater: evaluation of condensate treatability through SBR and constructed Wetlands. Ecol Eng 2015; 80: 156–61.
    • (2015) Ecol Eng , vol.80 , pp. 156-161
    • Masi, F.1    Bresciani, R.2    Munz, G.3    Lubello, C.4
  • 30
    • 79955023092 scopus 로고    scopus 로고
    • Functional milk beverage fortified with phenolic compounds extracted from olive vegetation water, and fermented with functional lactic acid bacteria
    • Servili M, Rizzello CG, Taticchi A, Esposto S, Urbani S, Mazzacane F, et al. Functional milk beverage fortified with phenolic compounds extracted from olive vegetation water, and fermented with functional lactic acid bacteria. Int J Food Microbiol 2011; 147: 45–52.
    • (2011) Int J Food Microbiol , vol.147 , pp. 45-52
    • Servili, M.1    Rizzello, C.G.2    Taticchi, A.3    Esposto, S.4    Urbani, S.5    Mazzacane, F.6
  • 31
    • 0033529748 scopus 로고    scopus 로고
    • Enzymatic activation of oleuropein: a protein crosslinker used as a chemical defense in the privet tree
    • Konno K, Hirayama C, Yasui H, Nakamura M. Enzymatic activation of oleuropein: a protein crosslinker used as a chemical defense in the privet tree. Proc Natl Acad Sci U S A 1999; 96: 9159–64.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9159-9164
    • Konno, K.1    Hirayama, C.2    Yasui, H.3    Nakamura, M.4
  • 33
    • 0030046826 scopus 로고    scopus 로고
    • Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions
    • Bartolini L, Casamenti F, Pepeu G. Aniracetam restores object recognition impaired by age, scopolamine, and nucleus basalis lesions. Pharmacol Biochem Behav 1996; 53: 277–83.
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 277-283
    • Bartolini, L.1    Casamenti, F.2    Pepeu, G.3
  • 34
    • 2942555108 scopus 로고    scopus 로고
    • On the delay-dependent involvement of the hippocampus in object recognition memory
    • Hammond RS, Tull LE, Stackman RW. On the delay-dependent involvement of the hippocampus in object recognition memory. Neurobiol Learn Mem 2004; 82: 26–34.
    • (2004) Neurobiol Learn Mem , vol.82 , pp. 26-34
    • Hammond, R.S.1    Tull, L.E.2    Stackman, R.W.3
  • 35
    • 77950358315 scopus 로고    scopus 로고
    • Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease
    • Greco SJ, Bryan KJ, Sarkar S, Zhu X, Smith MA, Ashford JW, et al. Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis 2010; 19: 1155–67.
    • (2010) J Alzheimers Dis , vol.19 , pp. 1155-1167
    • Greco, S.J.1    Bryan, K.J.2    Sarkar, S.3    Zhu, X.4    Smith, M.A.5    Ashford, J.W.6
  • 36
    • 78650904823 scopus 로고    scopus 로고
    • Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice
    • Fiorentini A, Rosi MC, Grossi C, Luccarini I, Casamenti F. Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice. PLoS One 2010; 5: e14382.
    • (2010) PLoS One , vol.5
    • Fiorentini, A.1    Rosi, M.C.2    Grossi, C.3    Luccarini, I.4    Casamenti, F.5
  • 37
    • 67849106894 scopus 로고    scopus 로고
    • Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease
    • Grossi C, Francese S, Casini A, Rosi MC, Luccarini I, Fiorentini A, et al. Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis 2009; 17: 423–40.
    • (2009) J Alzheimers Dis , vol.17 , pp. 423-440
    • Grossi, C.1    Francese, S.2    Casini, A.3    Rosi, M.C.4    Luccarini, I.5    Fiorentini, A.6
  • 39
    • 84959495688 scopus 로고    scopus 로고
    • Oral administration of oleuropein attenuates cisplatin-induced acute renal injury in mice through inhibition of ERK signaling
    • Potočnjak I, Škoda M, Pernjak-Pugel E, Peršić MP, Domitrović R. Oral administration of oleuropein attenuates cisplatin-induced acute renal injury in mice through inhibition of ERK signaling. Mol Nutr Food Res 2016; 60: 530–41.
    • (2016) Mol Nutr Food Res , vol.60 , pp. 530-541
    • Potočnjak, I.1    Škoda, M.2    Pernjak-Pugel, E.3    Peršić, M.P.4    Domitrović, R.5
  • 40
    • 80054988630 scopus 로고    scopus 로고
    • Oleuropein and hydroxytyrosol inhibit adipocyte differentiation in 3 T3-L1 cells
    • Drira R, Chen S, Sakamoto K. Oleuropein and hydroxytyrosol inhibit adipocyte differentiation in 3 T3-L1 cells. Life Sci 2011; 89: 708–16.
    • (2011) Life Sci , vol.89 , pp. 708-716
    • Drira, R.1    Chen, S.2    Sakamoto, K.3
  • 41
    • 84944790420 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease
    • Turner RS, Thomas RG, Craft S, van Dyck CH, Mintzer J, Reynolds BA, et al. A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease. Neurology 2015; 85: 1383–91.
    • (2015) Neurology , vol.85 , pp. 1383-1391
    • Turner, R.S.1    Thomas, R.G.2    Craft, S.3    van Dyck, C.H.4    Mintzer, J.5    Reynolds, B.A.6
  • 42
    • 84875953344 scopus 로고    scopus 로고
    • Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases
    • Del Rio D, Rodriguez-Mateos A, Spencer JP, Tognolini M, Borges G, Crozier A. Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal 2013; 18: 1818–92.
    • (2013) Antioxid Redox Signal , vol.18 , pp. 1818-1892
    • Del Rio, D.1    Rodriguez-Mateos, A.2    Spencer, J.P.3    Tognolini, M.4    Borges, G.5    Crozier, A.6
  • 43
    • 84920833547 scopus 로고    scopus 로고
    • Nutraceuticals and amyloid neurodegenerative diseases: a focus on natural phenols
    • Rigacci S, Stefani M. Nutraceuticals and amyloid neurodegenerative diseases: a focus on natural phenols. Expert Rev Neurother 2015; 15: 41–52.
    • (2015) Expert Rev Neurother , vol.15 , pp. 41-52
    • Rigacci, S.1    Stefani, M.2
  • 44
  • 46
    • 67650875899 scopus 로고    scopus 로고
    • Amyloid deposition is associated with impaired default network function in older persons without dementia
    • Sperling RA, Laviolette PS, O'Keefe K, O'Brien J, Rentz DM, Pihlajamaki M, et al. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron 2009; 63: 178–88.
    • (2009) Neuron , vol.63 , pp. 178-188
    • Sperling, R.A.1    Laviolette, P.S.2    O'Keefe, K.3    O'Brien, J.4    Rentz, D.M.5    Pihlajamaki, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.