Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice

Cell Death and Disease

Volumn 6, Issue 5, 2015, Pages

  Bortolussi, G ^a   Codarin, E ^b   Antoniali, G ^b   Vascotto, C ^b   Vodret, S ^a   Arena, S ^c   Cesaratto, L ^b   Scaloni, A ^c   Tell, G ^b   Muro, A F ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b UNIVERSITY OF UDINE   (Italy)

^c CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; DJ 1 PROTEIN; OXIDOREDUCTASE; PEROXIREDOXIN 2; PEROXIREDOXIN 6; SUPEROXIDE DISMUTASE; ANTIOXIDANT; GLUCURONOSYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; CELL DEATH; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVITY; GENE MUTATION; HYPERBILIRUBINEMIA; IN VIVO STUDY; INVESTIGATIVE PROCEDURES; MALE; MOUSE; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROTOXICITY; NEWBORN JAUNDICE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; QUANTITATIVE STUDY; VALIDATION STUDY; WILD TYPE; ANIMAL; BLOOD; C57BL MOUSE; CYTOLOGY; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; OXIDATION REDUCTION REACTION; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ANTIOXIDANTS; BILIRUBIN; CELL DEATH; CEREBELLUM; DISEASE MODELS, ANIMAL; GLUCURONOSYLTRANSFERASE; HYPERBILIRUBINEMIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; OXIDATION-REDUCTION;

EID: 84970937538     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.113     Document Type: Article

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