메뉴 건너뛰기




Volumn 72, Issue 5, 2012, Pages 455-459

Lipid peroxidation is not the primary mechanism of bilirubin-induced neurologic dysfunction in jaundiced Gunn rat pups

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; 4 HYDROXYNONENAL; ANTIOXIDANT; BILIRUBIN; HYDROXY 1,12 PYRAZOLINOMINOCYCLINE; MINOCYCLINE; SULFADIMETHOXINE; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG;

EID: 84870553767     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2012.111     Document Type: Article
Times cited : (27)

References (37)
  • 1
    • 33749636448 scopus 로고    scopus 로고
    • Kernicterus and the molecular mechanisms of bilirubin-induced CNS injury in newborns
    • Watchko JF. Kernicterus and the molecular mechanisms of bilirubin-induced CNS injury in newborns. Neuromolecular Med 2006;8:513-29.
    • (2006) Neuromolecular Med , vol.8 , pp. 513-529
    • Watchko, J.F.1
  • 2
    • 5044220926 scopus 로고    scopus 로고
    • A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes
    • DOI 10.1016/j.brainres.2004.07.063, PII S0006899304012508
    • Brito MA, Brites D, Butterfield DA. A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes. Brain Res 2004;1026:33-43. (Pubitemid 39336414)
    • (2004) Brain Research , vol.1026 , Issue.1 , pp. 33-43
    • Brito, M.A.1    Brites, D.2    Butterfield, D.A.3
  • 3
    • 39749156518 scopus 로고    scopus 로고
    • Bilirubin injury to neurons: Contribution of oxidative stress and rescue by glycoursodeoxycholic acid
    • Brito MA, Lima S, Fernandes A, et al. Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid. Neurotoxicology 2008;29:259-69.
    • (2008) Neurotoxicology , vol.29 , pp. 259-269
    • Brito, M.A.1    Lima, S.2    Fernandes, A.3
  • 5
    • 0036061982 scopus 로고    scopus 로고
    • Effect of 7-nitroindazole on bilirubin-induced changes in brain cell membrane function and energy metabolism in newborn piglets
    • DOI 10.1159/000064154
    • Park WS, Chang YS, Lee M. Effect of 7-nitroindazole on bilirubin-induced changes in brain cell membrane function and energy metabolism in newborn piglets. Biol Neonate 2002;82:61-5. (Pubitemid 34765135)
    • (2002) Biology of the Neonate , vol.82 , Issue.1 , pp. 61-65
    • Park, W.S.1    Chang, Y.S.2    Lee, M.3
  • 6
    • 34548454884 scopus 로고    scopus 로고
    • Glycoursodeoxycholic acid and interleukin-10 modulate the reactivity of rat cortical astrocytes to unconjugated bilirubin
    • DOI 10.1097/nen.0b013e3181461c74, PII 0000507220070900000003
    • Fernandes A, Vaz AR, Falc AS, Silva RF, Brito MA, Brites D. Glycoursodeoxycholic acid and interleukin-10 modulate the reactivity of rat cortical astrocytes to unconjugated bilirubin. J Neuropathol Exp Neurol 2007;66:789-98. (Pubitemid 47360954)
    • (2007) Journal of Neuropathology and Experimental Neurology , vol.66 , Issue.9 , pp. 789-798
    • Fernandes, A.1    Vaz, A.R.2    Falcao, A.S.3    Silva, R.F.M.4    Brito, M.A.5    Brites, D.6
  • 7
    • 0035072101 scopus 로고    scopus 로고
    • Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid
    • DOI 10.1016/S0168-8278(01)00015-0, PII S0168827801000150
    • Silva RF, Rodrigues CM, Brites D. Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid. J Hepatol 2001;34:402-8. (Pubitemid 32240819)
    • (2001) Journal of Hepatology , vol.34 , Issue.3 , pp. 402-408
    • Silva, R.F.M.1    Rodrigues, C.M.P.2    Brites, D.3
  • 9
    • 23244453399 scopus 로고    scopus 로고
    • Antioxidant properties of minocycline: Neuroprotection in an oxidative stress assay and direct radical-scavenging activity
    • DOI 10.1111/j.1471-4159.2005.03219.x
    • Kraus RL, Pasieczny R, Lariosa-Willingham K, Turner MS, Jiang A, Trauger JW. Antioxidant properties of minocycline: neuroprotection in an oxidative stress assay and direct radical-scavenging activity. J Neurochem 2005;94:819-27. (Pubitemid 41098513)
    • (2005) Journal of Neurochemistry , vol.94 , Issue.3 , pp. 819-827
    • Kraus, R.L.1    Pasieczny, R.2    Lariosa-Willingham, K.3    Turner, M.S.4    Jiang, A.5    Trauger, J.W.6
  • 10
    • 23044460297 scopus 로고    scopus 로고
    • Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia-induced cerebellar hypoplasia in the Gunn rat
    • DOI 10.1111/j.1460-9568.2005.04182.x
    • Lin S, Wei X, Bales KR, et al. Minocycline blocks bilirubin neurotoxicity and prevents hyperbilirubinemia-induced cerebellar hypoplasia in the Gunn rat. Eur J Neurosci 2005;22:21-7. (Pubitemid 41059968)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.1 , pp. 21-27
    • Lin, S.1    Wei, X.2    Bales, K.R.3    Paul, A.B.C.4    Ma, Z.5    Yan, G.6    Paul, S.M.7    Du, Y.8
  • 11
    • 36248932681 scopus 로고    scopus 로고
    • Minocycline blocks acute bilirubin-induced neurological dysfunction in jaundiced Gunn rats
    • DOI 10.1159/000103740
    • Geiger AS, Rice AC, Shapiro SM. Minocycline blocks acute bilirubininduced neurological dysfunction in jaundiced Gunn rats. Neonatology 2007;92:219-26. (Pubitemid 350125278)
    • (2007) Neonatology , vol.92 , Issue.4 , pp. 219-226
    • Geiger, A.S.1    Rice, A.C.2    Shapiro, S.M.3
  • 14
    • 54949116146 scopus 로고    scopus 로고
    • A novel non-antibacterial nonchelating hydroxypyrazoline derivative of minocycline inhibits nociception and oedema in mice
    • Bastos LF, Angusti A, Vila MC, et al. A novel non-antibacterial, nonchelating hydroxypyrazoline derivative of minocycline inhibits nociception and oedema in mice. Br J Pharmacol 2008;155:714-21.
    • (2008) Br J Pharmacol , vol.155 , pp. 714-721
    • Bastos, L.F.1    Angusti, A.2    Vila, M.C.3
  • 16
    • 0034942512 scopus 로고    scopus 로고
    • The therapeutic effects of ursodeoxycholic acid as an anti-apoptotic agent
    • DOI 10.1517/13543784.10.7.1243
    • Rodrigues CM, Steer CJ. The therapeutic effects of ursodeoxycholic acid as an anti-apoptotic agent. Expert Opin Investig Drugs 2001;10:1243-53. (Pubitemid 32633568)
    • (2001) Expert Opinion on Investigational Drugs , vol.10 , Issue.7 , pp. 1243-1253
    • Rodrigues, C.M.P.1    Steer, C.J.2
  • 17
    • 0036202904 scopus 로고    scopus 로고
    • Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin
    • Silva RF, Rodrigues CM, Brites D. Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin. Pediatr Res 2002;51:535-41. (Pubitemid 34267328)
    • (2002) Pediatric Research , vol.51 , Issue.4 , pp. 535-541
    • Silva, R.F.M.1    Rodrigues, C.M.P.2    Brites, D.3
  • 18
    • 80052361500 scopus 로고    scopus 로고
    • Astrocytic-neuronal crosstalk: Implications for neuroprotection from brain injury
    • Barreto GE, Gonzalez J, Torres Y, Morales L. Astrocytic-neuronal crosstalk: implications for neuroprotection from brain injury. Neurosci Res 2011;71:107-13.
    • (2011) Neurosci Res , vol.71 , pp. 107-113
    • Barreto, G.E.1    Gonzalez, J.2    Torres, Y.3    Morales, L.4
  • 19
    • 0025281223 scopus 로고
    • Is bilirubin good for you?
    • McDonagh AF. Is bilirubin good for you? Clin Perinatol 1990;17:359-69.
    • (1990) Clin Perinatol , vol.17 , pp. 359-369
    • McDonagh, A.F.1
  • 20
    • 0032874845 scopus 로고    scopus 로고
    • Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress
    • DOI 10.1080/10715769900300851
    • Hayes JD, McLellan LI. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defense against oxidative stress. Free Rad Res 1999;31:273-300. (Pubitemid 29452854)
    • (1999) Free Radical Research , vol.31 , Issue.4 , pp. 273-300
    • Hayes, J.D.1    McLellan, L.I.2
  • 21
    • 33748041670 scopus 로고    scopus 로고
    • Calculated in vivo free bilirubin levels in the central nervous system of Gunn rat pups
    • DOI 10.1203/01.pdr.0000219561.07550.04, PII 0000645020060700000009
    • Daood MJ, Watchko JF. Calculated in vivo free bilirubin levels in the central nervous system of Gunn rat pups. Pediatr Res 2006;60:44-9. (Pubitemid 44297611)
    • (2006) Pediatric Research , vol.60 , Issue.1 , pp. 44-49
    • Daood, M.J.1    Watchko, J.F.2
  • 22
    • 0026077459 scopus 로고
    • Molecular basis for the lack of bilirubin-specific and 3-methylcholanthrene-inducible UDP-glucuronosyltransferase activities in Gunn rats. The two isoforms are encoded by distinct mRNA species that share an identical single base deletion
    • Roy-Chowdhury J, Huang TJ, Kesari K, Lederstein M, Arias IM, Roy-Chowdhury N. Molecular basis for the lack of bilirubin-specific and 3-methylcholanthrene-inducible UDP-glucuronosyltransferase activities in Gunn rats. The two isoforms are encoded by distinct mRNA species that share an identical single base deletion. J Biol Chem 1991; 266:18294-8.
    • (1991) J Biol Chem , vol.266 , pp. 18294-18298
    • Roy-Chowdhury, J.1    Huang, T.J.2    Kesari, K.3    Lederstein, M.4    Arias, I.M.5    Roy-Chowdhury, N.6
  • 23
    • 1842315356 scopus 로고
    • Kernicterus in rats lacking glucuronyl transferase. II. Factors which alter bilirubin concentration and frequency of kernicterus
    • Johnson L, Garcia ML, Figueroa E, Sarmiento F. Kernicterus in rats lacking glucuronyl transferase. II. Factors which alter bilirubin concentration and frequency of kernicterus. Am J Dis Child 1961;101:322-49.
    • (1961) Am J Dis Child , vol.101 , pp. 322-349
    • Johnson, L.1    Garcia, M.L.2    Figueroa, E.3    Sarmiento, F.4
  • 24
    • 84937165905 scopus 로고
    • Studies on kernicterus; Relationship with sulfonamide intoxication, report on kernicterus in rats with glucuronyl transferase deficiency and review of pathogenesis
    • discussion 187-9
    • Blanc WA, Johnson L. Studies on kernicterus; relationship with sulfonamide intoxication, report on kernicterus in rats with glucuronyl transferase deficiency and review of pathogenesis. J Neuropathol Exp Neurol 1959;18:165-87; discussion 187-9.
    • (1959) J Neuropathol Exp Neurol , vol.18 , pp. 165-187
    • Blanc, W.A.1    Johnson, L.2
  • 25
    • 0014627334 scopus 로고
    • Clinical signs and morphologic abnormalities in Gunn rats treated with sulfadimethoxine
    • Schutta HS, Johnson L. Clinical signs and morphologic abnormalities in Gunn rats treated with sulfadimethoxine. J Pediatr 1969;75:1070-9.
    • (1969) J Pediatr , vol.75 , pp. 1070-1079
    • Schutta, H.S.1    Johnson, L.2
  • 26
    • 33745829451 scopus 로고    scopus 로고
    • Sex-specific regional brain bilirubin content in hyperbilirubinemic gunn rat pups
    • DOI 10.1159/000091843
    • Cannon C, Daood MJ, O'Day TL, Watchko JF. Sex-specific regional brain bilirubin content in hyperbilirubinemic Gunn rat pups. Biol Neonate 2006;90:40-5. (Pubitemid 44034405)
    • (2006) Biology of the Neonate , vol.90 , Issue.1 , pp. 40-45
    • Cannon, C.1    Daood, M.J.2    O'Day, T.L.3    Watchko, J.F.4
  • 28
    • 0014108489 scopus 로고
    • Bilirubin encephalopathy in the Gunn rat: A fine structure study of the cerebellar cortex
    • Schutta HS, Johnson L. Bilirubin encephalopathy in the Gunn rat: a fine structure study of the cerebellar cortex. J Neuropathol Exp Neurol 1967;26:377-96.
    • (1967) J Neuropathol Exp Neurol , vol.26 , pp. 377-396
    • Schutta, H.S.1    Johnson, L.2
  • 30
    • 0034799214 scopus 로고    scopus 로고
    • A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease
    • DOI 10.1006/exnr.2001.7755
    • Keene CD, Rodrigues CM, Eich T, et al. A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease. Exp Neurol 2001;171:351-60. (Pubitemid 32955297)
    • (2001) Experimental Neurology , vol.171 , Issue.2 , pp. 351-360
    • Keene C.Dirk1    Rodrigues, C.M.P.2    Eich, T.3    Linehan-Stieers, C.4    Abt, A.5    Kren, B.T.6    Steer, C.J.7    Low, W.C.8
  • 31
    • 78650127298 scopus 로고    scopus 로고
    • Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration
    • Oveson BC, Iwase T, Hackett SF, et al. Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration. J Neurochem 2011;116:144-53.
    • (2011) J Neurochem , vol.116 , pp. 144-153
    • Oveson, B.C.1    Iwase, T.2    Hackett, S.F.3
  • 32
    • 43049096711 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats
    • Colak A, Kelten B, Sagmanligil A, et al. Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats. J Clin Neurosci 2008;15:665-71.
    • (2008) J Clin Neurosci , vol.15 , pp. 665-671
    • Colak, A.1    Kelten, B.2    Sagmanligil, A.3
  • 33
    • 0034327232 scopus 로고    scopus 로고
    • Bilirubin and amyloid-peptide induce cytochrome c release through mitochondrial membrane permeabilization
    • Rodrigues CM, SolS, Silva R, Brites D. Bilirubin and amyloid-peptide induce cytochrome c release through mitochondrial membrane permeabilization. Mol Med 2000;6:936-46.
    • (2000) Mol Med , vol.6 , pp. 936-946
    • Rodrigues, C.M.1    Sol, S.2    Silva, R.3    Brites, D.4
  • 34
    • 0013877717 scopus 로고
    • Improved micro-method for determination of serum bilirubin
    • Martinek RG. Improved micro-method for determination of serum bilirubin. Clin Chim Acta 1966;13:161-70.
    • (1966) Clin Chim Acta , vol.13 , pp. 161-170
    • Martinek, R.G.1
  • 35
    • 0037411282 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal: A product and mediator of oxidative stress
    • DOI 10.1016/S0163-7827(03)00014-6
    • Uchida K. 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog Lipid Res 2003;42:318-43. (Pubitemid 36411689)
    • (2003) Progress in Lipid Research , vol.42 , Issue.4 , pp. 318-343
    • Uchida, K.1
  • 36
    • 79960995847 scopus 로고    scopus 로고
    • Sweet and sour-oxidative and carbonyl stress in neurological disorders
    • Harris RA, Amor S. Sweet and sour-oxidative and carbonyl stress in neurological disorders. CNS Neurol Disord Drug Targets 2011; 10:82-107.
    • (2011) CNS Neurol Disord Drug Targets , vol.10 , pp. 82-107
    • Harris, R.A.1    Amor, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.