Enhanced brain-derived neurotrophic factor delivery by ultrasound and microbubbles promotes white matter repair after stroke

Biomaterials

Volumn 100, Issue , 2016, Pages 41-52

  Rodríguez Frutos, Berta ^a   Otero Ortega, Laura ^a   Ramos Cejudo, Jaime ^a   Martínez Sánchez, Patricia ^a   Barahona Sanz, Inés ^a   Navarro Hernanz, Teresa ^b   Gómez de Frutos, María del Carmen ^a   Díez Tejedor, Exuperio ^a   Gutiérrez Fernández, María ^a  

^a HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

^b INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

Author keywords

BDNF; Brain repair; Microbubbles; Subcortical stroke; Ultrasound; White matter injury

Indexed keywords

ANIMALS; REPAIR; ULTRASONICS;

BDNF; BRAIN-DERIVED NEUROTROPHIC FACTORS; CONNECTIVITY RESTORATIONS; EXPERIMENTAL ANIMALS; MICROBUBBLES; SUBCORTICAL STROKE; ULTRASOUND-TARGETED MICROBUBBLE DESTRUCTION; WHITE MATTER;

ULTRASONIC APPLICATIONS;

BIOLOGICAL MARKER; BRAIN DERIVED NEUROTROPHIC FACTOR; ENDOTHELIN 1; MYELIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; CONNECTOME; CONTROLLED STUDY; CONVALESCENCE; MALE; MICROBUBBLE; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; REMYELINIZATION; ULTRASOUND; ULTRASOUND TARGETED MICROBUBBLE DESTRUCTION; WHITE MATTER INJURY; ANIMAL; BRAIN; CELL LINE; DRUG DELIVERY SYSTEM; DRUG EFFECTS; PATHOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; WHITE MATTER;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL LINE; DRUG DELIVERY SYSTEMS; MALE; MICROBUBBLES; OLIGODENDROGLIA; RATS, SPRAGUE-DAWLEY; STROKE; ULTRASONIC WAVES; ULTRASONICS; WHITE MATTER;

EID: 84970028635     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.05.028     Document Type: Article

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