Targeted antiangiogenesis gene therapy using targeted cationic microbubbles conjugated with CD105 antibody compared with untargeted cationic and neutral microbubbles

Theranostics

Volumn 5, Issue 4, 2015, Pages 399-417

  Zhou, Yu ^a   Gu, Haitao ^a   Xu, Yan ^a   Li, Fan ^c   Kuang, Shaojing ^d   Wang, Zhigang ^a   Zhou, Xiyuan ^a   Ma, Huafeng ^a   Li, Pan ^a   Zheng, Yuanyi ^a   Ran, Haitao ^a   Jian, Jia ^a   Zhao, Yajing ^a   Song, Weixiang ^a   Wang, Qiushi ^e   Wang, Dong ^b  

^a THE SECOND AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^b CHILDREN S HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^c THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^d Third People's Hospital of Chongqing   (China)

^e Chongqing Jinxin Advertisement Company Chongqing Daily News Group   (China)

Author keywords

Antiangiogenesis; Cationic microbubbles; Target; Ultrasound mediated gene delivery (UMGD)

Indexed keywords

ANTIBODY; CD105 ANTIBODY; ENDOSTATIN; PLASMID DNA; UNCLASSIFIED DRUG; DNA; DRUG CARRIER; ENDOGLIN PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC GENE THERAPY; ANTIGEN BINDING; APOPTOSIS; ARTICLE; BREAST CANCER; CAPILLARY ENDOTHELIAL CELL; CATIONIC MICROBUBBLE; CELL CYCLE; CELL INVASION; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; ENDOSTATIN GENE; FEMALE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICROBUBBLE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NEUTRAL MICROBUBBLE; NONHUMAN; TUMOR VOLUME; ULTRASOUND; ZETA POTENTIAL; ANIMAL; CELL CULTURE; DRUG DELIVERY SYSTEM; ENDOTHELIUM CELL; GENE THERAPY; GENETICS; IMMUNOLOGY; METABOLISM; NEOVASCULARIZATION, PATHOLOGIC; NUDE MOUSE; PLASMID; PROCEDURES; TREATMENT OUTCOME;

ANIMALS; ANTIBODIES; CELLS, CULTURED; DNA; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOSTATINS; ENDOTHELIAL CELLS; GENETIC THERAPY; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE, NUDE; MICROBUBBLES; NEOVASCULARIZATION, PATHOLOGIC; PLASMIDS; TREATMENT OUTCOME;

EID: 84924332932     PISSN: None     EISSN: 18387640     Source Type: Journal    
DOI: 10.7150/thno.10351     Document Type: Article

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