RNA Interference Prevents Autosomal-Dominant Hearing Loss

American Journal of Human Genetics

Volumn 98, Issue 6, 2016, Pages 1101-1113

  Shibata, Seiji B ^a   Ranum, Paul T ^a,b   Moteki, Hideaki ^a,c   Pan, Bifeng ^d   Goodwin, Alexander T ^a   Goodman, Shawn S ^e   Abbas, Paul J ^e   Holt, Jeffrey R ^d   Smith, Richard J H ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e The University of Iowa   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; PARVOVIRUS VECTOR; MEMBRANE PROTEIN; TMC1 PROTEIN, MOUSE; TMC2 PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL DOMINANT HEARING LOSS; CELL SURVIVAL; CONTROLLED STUDY; DISEASE COURSE; FEASIBILITY STUDY; GAIN OF FUNCTION MUTATION; GENE; GENE EXPRESSION; HAIR CELL; HEARING IMPAIRMENT; INTRACOCHLEAR DRUG ADMINISTRATION; MISSENSE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; TMC1 GENE; TREATMENT OUTCOME; VIRAL GENE THERAPY; ANIMAL; ANTAGONISTS AND INHIBITORS; AUDITORY NERVOUS SYSTEM; C3H MOUSE; DEPENDOPARVOVIRUS; GENETICS; HEARING LOSS; HUMAN; KNOCKOUT MOUSE; MECHANOTRANSDUCTION; PATHOLOGY; PHYSIOLOGY;

ANIMALS; AUDITORY PATHWAYS; DEPENDOVIRUS; HEARING LOSS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE PROTEINS; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; MICRORNAS; MUTATION, MISSENSE; RNA INTERFERENCE;

EID: 84969916828     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2016.03.028     Document Type: Article

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