Short-chain fatty acid acetate stimulates adipogenesis and mitochondrial biogenesis via GPR43 in brown adipocytes

Endocrinology

Volumn 157, Issue 5, 2016, Pages 1881-1894

  Hu, Jiamiao ^a   Kyrou, Ioannis ^b,f,g   Tan, Bee K ^a,b,c   Dimitriadis, Georgios K ^a,b   Ramanjaneya, Manjunath ^d   Tripathi, Gyanendra ^a   Patel, Vanlata ^a   James, Sean ^c   Kawan, Mohamed ^a   Chen, Jing ^a,e   Randeva, Harpal S ^a,b,f,g  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b Warwickshire Institute for the Study of Diabetes   (United States)

^c UNIVERSITY HOSPITALS COVENTRY AND WARWICKSHIRE NHS TRUST   (United Kingdom)

^d UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

^e HAMAD MEDICAL CORPORATION   (Qatar)

^f JINING MEDICAL UNIVERSITY   (China)

^g ASTON UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ACETIC ACID; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR 43; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOLIPASE C; PROTEIN KINASE C; RECEPTOR; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; FABP4 PROTEIN, MOUSE; FATTY ACID BINDING PROTEIN; FFAR2 PROTEIN, MOUSE; G PROTEIN COUPLED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOCYTE; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FERMENTATION; INTESTINE; MALE; MITOCHONDRIAL BIOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE METABOLISM; ANIMAL; DRUG EFFECTS; METABOLISM; MITOCHONDRION; ORGANELLE BIOGENESIS; SIGNAL TRANSDUCTION; UPREGULATION;

ACETIC ACID; ADIPOCYTES, BROWN; ADIPOGENESIS; ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FATTY ACID-BINDING PROTEINS; MICE; MITOCHONDRIA; ORGANELLE BIOGENESIS; PPAR GAMMA; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; UNCOUPLING PROTEIN 1; UP-REGULATION;

EID: 84969785434     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1944     Document Type: Article

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