Bio-orthogonal Immobilization of Fibroblast Growth Factor 2 for Spatial Controlled Cell Proliferation

ACS Biomaterials Science and Engineering

Volumn 1, Issue 9, 2015, Pages 740-746

  Lühmann, Tessa ^a   Jones, Gabriel ^a   Gutmann, Marcus ^a   Rybak, Jens Christoph ^a   Nickel, Joachim ^a,b   Rubini, Marina ^c   Meinel, Lorenz ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^c UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

bio orthogonal immobilization; decoration; fibroblast growth factor 2 (FGF 2); genetic codon expansion; proliferation

Indexed keywords

ALKYNE DERIVATIVE; FIBROBLAST GROWTH FACTOR 2; LYSINE; PROPARGYLLYSINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; CYCLOADDITION; HUMAN; HUMAN CELL; ISOELECTRIC POINT; NONHUMAN; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; PROTEIN STRUCTURE; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

EID: 84969242818     PISSN: None     EISSN: 23739878     Source Type: Journal    
DOI: 10.1021/acsbiomaterials.5b00236     Document Type: Article

References (40)

1. Lee, K.; Silva, E. A.; Mooney, D. J. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments J. R. Soc., Interface 2011, 8, 153-170 10.1098/rsif.2010.0223
2. Masters, K. S. Covalent growth factor immobilization strategies for tissue repair and regeneration Macromol. Biosci. 2011, 11, 1149-1163 10.1002/mabi.201000505
3. Pompe, T.; Salchert, K.; Alberti, K.; Zandstra, P.; Werner, C. Immobilization of growth factors on solid supports for the modulation of stem cell fate Nat. Protoc. 2010, 5, 1042-1050 10.1038/nprot.2010.70
4. Lienemann, P. S.; Lutolf, M. P.; Ehrbar, M. Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration Adv. Drug Delivery Rev. 2012, 64, 1078-1089 10.1016/j.addr.2012.03.010
5. Ehrbar, M.; Rizzi, S. C.; Hlushchuk, R.; Djonov, V.; Zisch, A. H.; Hubbell, J. A.; Weber, F. E.; Lutolf, M. P. Enzymatic formation of modular cell-instructive fibrin analogs for tissue engineering Biomaterials 2007, 28, 3856-3866 10.1016/j.biomaterials.2007.03.027
6. Lühmann, T.; Hall, H. Cell Guidance by 3D-Gradients in Hydrogel Matrices: Importance for Biomedical Applications Materials 2009, 2, 1058-1083 10.3390/ma2031058
7. Holland-Nell, K.; Beck-Sickinger, A. G. Specifically immobilised aldo/keto reductase AKR1A1 shows a dramatic increase in activity relative to the randomly immobilised enzyme ChemBioChem 2007, 8, 1071-1076 10.1002/cbic.200700056
8. Carragee, E. J.; Hurwitz, E. L.; Weiner, B. K. A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned Spine J. 2011, 11, 471-491 10.1016/j.spinee.2011.04.023
9. Zhao, H.; Heusler, E.; Jones, G.; Li, L.; Werner, V.; Germershaus, O.; Ritzer, J.; Luehmann, T.; Meinel, L. Decoration of silk fibroin by click chemistry for biomedical application J. Struct. Biol. 2014, 186, 420-430 10.1016/j.jsb.2014.02.009
10. Steen Redeker, E.; Ta, D. T.; Cortens, D.; Billen, B.; Guedens, W.; Adriaensens, P. Protein engineering for directed immobilization Bioconjugate Chem. 2013, 24, 1761-1777 10.1021/bc4002823
11. Noren, C. J.; Anthony-Cahill, S. J.; Griffith, M. C.; Schultz, P. G. A general method for site-specific incorporation of unnatural amino acids into proteins Science 1989, 244, 182-188 10.1126/science.2649980
12. Chin, J. W. Molecular biology. Reprogramming the genetic code Science 2012, 336, 428-429 10.1126/science.1221761
13. Gaston, M. A.; Jiang, R.; Krzycki, J. A. Functional context, biosynthesis, and genetic encoding of pyrrolysine Curr. Opin. Microbiol. 2011, 14, 342-349 10.1016/j.mib.2011.04.001
14. James, C. M.; Ferguson, T. K.; Leykam, J. F.; Krzycki, J. A. The amber codon in the gene encoding the monomethylamine methyltransferase isolated from Methanosarcina barkeri is translated as a sense codon J. Biol. Chem. 2001, 276, 34252-34258 10.1074/jbc.M102929200
15. Blight, S. K.; Larue, R. C.; Mahapatra, A.; Longstaff, D. G.; Chang, E.; Zhao, G.; Kang, P. T.; Green-Church, K. B.; Chan, M. K.; Krzycki, J. A. Direct charging of tRNA(CUA) with pyrrolysine in vitro and in vivo Nature 2004, 431, 333-335 10.1038/nature02895
16. Eger, S.; Scheffner, M.; Marx, A.; Rubini, M. Formation of ubiquitin dimers via azide-alkyne click reaction Methods Mol. Biol. 2012, 832, 589-596 10.1007/978-1-61779-474-2-41
17. Nguyen, D. P.; Lusic, H.; Neumann, H.; Kapadnis, P. B.; Deiters, A.; Chin, J. W. Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry J. Am. Chem. Soc. 2009, 131, 8720-8721 10.1021/ja900553w
18. Gospodarowicz, D.; Ferrara, N.; Schweigerer, L.; Neufeld, G. Structural characterization and biological functions of fibroblast growth factor Endocr. Rev. 1987, 8, 95-114 10.1210/edrv-8-2-95
19. Tomanek, R. J.; Hansen, H. K.; Christensen, L. P. Temporally expressed PDGF and FGF-2 regulate embryonic coronary artery formation and growth Arterioscler., Thromb., Vasc. Biol. 2008, 28, 1237-1243 10.1161/ATVBAHA.108.166454
20. Uebersax, L.; Merkle, H. P.; Meinel, L. Biopolymer-based growth factor delivery for tissue repair: from natural concepts to engineered systems Tissue Eng., Part B 2009, 15, 263-289 10.1089/ten.teb.2008.0668
21. Beenken, A.; Mohammadi, M. The FGF family: biology, pathophysiology and therapy Nat. Rev. Drug Discovery 2009, 8, 235-253 10.1038/nrd2792
22. Yun, Y. R.; Won, J. E.; Jeon, E.; Lee, S.; Kang, W.; Jo, H.; Jang, J. H.; Shin, U. S.; Kim, H. W. Fibroblast growth factors: biology, function, and application for tissue regeneration J. Tissue Eng. 2010, 2010, 218142 10.4061/2010/218142
23. Nugent, M. A.; Iozzo, R. V. Fibroblast growth factor-2 Int. J. Biochem. Cell Biol. 2000, 32, 115-120 10.1016/S1357-2725(99)00123-5
24. Gospodarowicz, D. Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth Nature 1974, 249, 123-127 10.1038/249123a0
25. Springer, B. A.; Pantoliano, M. W.; Barbera, F. A.; Gunyuzlu, P. L.; Thompson, L. D.; Herblin, W. F.; Rosenfeld, S. A.; Book, G. W. Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis J. Biol. Chem. 1994, 269, 26879-26884
26. Klagsbrun, M.; Smith, S.; Sullivan, R.; Shing, Y.; Davidson, S.; Smith, J. A.; Sasse, J. Multiple forms of basic fibroblast growth factor: amino-terminal cleavages by tumor cell- and brain cell-derived acid proteinases Proc. Natl. Acad. Sci. U. S. A. 1987, 84, 1839-1843 10.1073/pnas.84.7.1839
27. Kastrup, J. S.; Eriksson, E. S.; Dalboge, H.; Flodgaard, H. X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form Acta Crystallogr., Sect. D: Biol. Crystallogr. 1997, 53, 160-168 10.1107/S0907444996012711
28. Eger, S.; Scheffner, M.; Marx, A.; Rubini, M. Synthesis of defined ubiquitin dimers J. Am. Chem. Soc. 2010, 132, 16337-16339 10.1021/ja1072838
29. Estape, D.; van den Heuvel, J.; Rinas, U. Susceptibility towards intramolecular disulphide-bond formation affects conformational stability and folding of human basic fibroblast growth factor Biochem. J. 1998, 335 (Pt 2) 343-349
30. Campbell, P. G.; Miller, E. D.; Fisher, G. W.; Walker, L. M.; Weiss, L. E. Engineered spatial patterns of FGF-2 immobilized on fibrin direct cell organization Biomaterials 2005, 26, 6762-6770 10.1016/j.biomaterials.2005.04.032
31. Presolski, S. I.; Hong, V. P.; Finn, M. G. Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation Curr. Protoc. Chem. Biol. 2011, 3, 153-162 10.1002/9780470559277.ch110148
32. Cheung, H. Y.; Lau, K. T.; Lu, T. P.; Hui, D. A critical review on polymer-based bio-engineered materials for scaffold development Composites, Part B 2007, 38, 291-300 10.1016/j.compositesb.2006.06.014
33. Duckworth, B. P.; Xu, J.; Taton, T. A.; Guo, A.; Distefano, M. D. Site-specific, covalent attachment of proteins to a solid surface Bioconjugate Chem. 2006, 17, 967-974 10.1021/bc060125e
34. Lee, P. L.; Johnson, D. E.; Cousens, L. S.; Fried, V. A.; Williams, L. T. Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor Science 1989, 245, 57-60 10.1126/science.2544996
35. Fox, G. M.; Schiffer, S. G.; Rohde, M. F.; Tsai, L. B.; Banks, A. R.; Arakawa, T. Production, biological activity, and structure of recombinant basic fibroblast growth factor and an analog with cysteine replaced by serine J. Biol. Chem. 1988, 263, 18452-18458
36. Volpato, F. Z.; Almodovar, J.; Erickson, K.; Popat, K. C.; Migliaresi, C.; Kipper, M. J. Preservation of FGF-2 bioactivity using heparin-based nanoparticles, and their delivery from electrospun chitosan fibers Acta Biomater. 2012, 8, 1551-1559 10.1016/j.actbio.2011.12.023
37. Princz, M. A.; Sheardown, H. Heparin-modified dendrimer cross-linked collagen matrices for the delivery of basic fibroblast growth factor (FGF-2) J. Biomater. Sci., Polym. Ed. 2008, 19, 1201-1218 10.1163/156856208785540181
38. Wenk, E.; Murphy, A. R.; Kaplan, D. L.; Meinel, L.; Merkle, H. P.; Uebersax, L. The use of sulfonated silk fibroin derivatives to control binding, delivery and potency of FGF-2 in tissue regeneration Biomaterials 2010, 31, 1403-1413 10.1016/j.biomaterials.2009.11.006
39. Wan, W.; Tharp, J. M.; Liu, W. R. Pyrrolysyl-tRNA synthetase: An ordinary enzyme but an outstanding genetic code expansion tool Biochim. Biophys. Acta, Proteins Proteomics 2014, 1844, 1059-1070 10.1016/j.bbapap.2014.03.002
40. Lang, K.; Chin, J. W. Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins Chem. Rev. 2014, 114, 4764-4806 10.1021/cr400355w