A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases

Oncotarget

Volumn 7, Issue 19, 2016, Pages 27764-27777

  Chen, Xilin ^a,b   Han, Jianfeng ^c   Chu, Jianhong ^c,d   Zhang, Lingling ^c   Zhang, Jianying ^e   Chen, Charlie ^c   Chen, Luxi ^c   Wang, Youwei ^c   Wang, Hongwei ^c   Yi, Long ^c   Elder, J Bradley ^c,e   Wang, Qi En ^e   He, Xiaoming ^f   Kaur, Balveen ^c,e   Chiocca, E Antonio ^g   Yu, Jianhua ^a,c  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b Beijing 307 Hospital   (China)

^c OHIO STATE UNIVERSITY   (United States)

^d SOOCHOW UNIVERSITY   (China)

^e OHIO STATE UNIVERSITY   (United States)

^f Ohio State University   (United States)

^g BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Breast cancer brain metastases; Chimeric antigen receptor; EGFR; Natural killer cells; oncolytic virus

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON; ONCOLYTIC HERPES VIRUS; EGFR PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOLYTIC VIRUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN METASTASIS; BREAST CANCER; BREAST CANCER BRAIN METASTASIS; BREAST CANCER CELL LINE; CANCER COMBINATION CHEMOTHERAPY; CELL KILLING; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG CYTOTOXICITY; DRUG EFFICACY; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IN VITRO STUDY; MONOTHERAPY; MOUSE; NATURAL KILLER CELL; NONHUMAN; ONCOLYTIC VIROTHERAPY; PROTEIN EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL THERAPY; BRAIN; BRAIN TUMOR; BREAST TUMOR; CELL ENGINEERING; CYTOTOXICITY; DRUG SCREENING; FEMALE; GENETICS; GLIOBLASTOMA; HUMAN ALPHAHERPESVIRUS 1; IMMUNOLOGY; MCF-7 CELL LINE; METABOLISM; MULTIMODALITY CANCER THERAPY; PATHOLOGY; PROCEDURES; SECONDARY;

ANIMALS; BRAIN; BRAIN NEOPLASMS; BREAST NEOPLASMS; CELL ENGINEERING; CELL- AND TISSUE-BASED THERAPY; COMBINED MODALITY THERAPY; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; GLIOBLASTOMA; HERPESVIRUS 1, HUMAN; HUMANS; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MCF-7 CELLS; MICE; ONCOLYTIC VIROTHERAPY; ONCOLYTIC VIRUSES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, ANTIGEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84968906601     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8526     Document Type: Article

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