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Volumn 21, Issue 14, 2015, Pages 3149-3159

Phase I hepatic immunotherapy for metastases study of intra-arterial chimeric antigen receptor-modified T-cell therapy for CEA+ liver metastases

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CHIMERIC ANTIGEN RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84942910678     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-14-1421     Document Type: Article
Times cited : (320)

References (47)
  • 1
    • 84875225709 scopus 로고    scopus 로고
    • Regulatory T cell infiltration predicts outcome following resection of colorectal cancer liver metastases
    • Katz SC, Bamboat ZM, Maker AV, Shia J, Pillarisetty VG, Yopp AC, et al. Regulatory T cell infiltration predicts outcome following resection of colorectal cancer liver metastases. Ann Surg Oncol 2013;20:946-55.
    • (2013) Ann Surg Oncol , vol.20 , pp. 946-955
    • Katz, S.C.1    Bamboat, Z.M.2    Maker, A.V.3    Shia, J.4    Pillarisetty, V.G.5    Yopp, A.C.6
  • 2
    • 78649648110 scopus 로고    scopus 로고
    • T cell infiltrate and outcome following resection of intermediate-grade primary neuroendocrine tumours and liver metastases
    • Katz SC, Donkor C, Glasgow K, Pillarisetty VG, Gonen M, Espat NJ, et al. T cell infiltrate and outcome following resection of intermediate-grade primary neuroendocrine tumours and liver metastases. HPB (Oxford) 2010;12:674-83.
    • (2010) HPB (Oxford) , vol.12 , pp. 674-683
    • Katz, S.C.1    Donkor, C.2    Glasgow, K.3    Pillarisetty, V.G.4    Gonen, M.5    Espat, N.J.6
  • 3
    • 68949204170 scopus 로고    scopus 로고
    • T cell infiltrate predicts long-term survival following resection of colorectal cancer liver metastases
    • Katz SC, Pillarisetty V, Bamboat ZM, Shia J, Hedvat C, Gonen M, et al. T cell infiltrate predicts long-term survival following resection of colorectal cancer liver metastases. Ann Surg Oncol 2009;16:2524-30.
    • (2009) Ann Surg Oncol , vol.16 , pp. 2524-2530
    • Katz, S.C.1    Pillarisetty, V.2    Bamboat, Z.M.3    Shia, J.4    Hedvat, C.5    Gonen, M.6
  • 4
    • 48149090897 scopus 로고    scopus 로고
    • Detection and functional analysis of tumor infiltrating T-lymphocytes (TIL) in liver metastases from colorectal cancer
    • Wagner P, Koch M, Nummer D, Palm S, Galindo L, Autenrieth D, et al. Detection and functional analysis of tumor infiltrating T-lymphocytes (TIL) in liver metastases from colorectal cancer. Ann Surg Oncol 2008;15:2310-7.
    • (2008) Ann Surg Oncol , vol.15 , pp. 2310-2317
    • Wagner, P.1    Koch, M.2    Nummer, D.3    Palm, S.4    Galindo, L.5    Autenrieth, D.6
  • 5
    • 84990018100 scopus 로고    scopus 로고
    • Tumor MHC class I expression improves the prognostic value of T-cell density in resected colorectal liver metastases
    • Turcotte S, Katz SC, Shia J, Jarnagin WR, Kingham TP, Allen PJ, et al. Tumor MHC class I expression improves the prognostic value of T-cell density in resected colorectal liver metastases. Cancer Immunol Res 2014;2:530-7.
    • (2014) Cancer Immunol Res , vol.2 , pp. 530-537
    • Turcotte, S.1    Katz, S.C.2    Shia, J.3    Jarnagin, W.R.4    Kingham, T.P.5    Allen, P.J.6
  • 6
    • 0014200984 scopus 로고
    • Hepatic suppression of sensitization to antigen absorbed into the portal system
    • Cantor HM, Dumont AE. Hepatic suppression of sensitization to antigen absorbed into the portal system. Nature 1967;215:744-5.
    • (1967) Nature , vol.215 , pp. 744-745
    • Cantor, H.M.1    Dumont, A.E.2
  • 7
    • 23044435839 scopus 로고    scopus 로고
    • Conventional liver CD4 T cells are functionally distinct and suppressed by environmental factors
    • Katz SC, Pillarisetty VG, Bleier JI, Kingham TP, Chaudhry UI, Shah AB, et al. Conventional liver CD4 T cells are functionally distinct and suppressed by environmental factors. Hepatology 2005;42:293-300.
    • (2005) Hepatology , vol.42 , pp. 293-300
    • Katz, S.C.1    Pillarisetty, V.G.2    Bleier, J.I.3    Kingham, T.P.4    Chaudhry, U.I.5    Shah, A.B.6
  • 9
    • 80051621753 scopus 로고    scopus 로고
    • Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis
    • Katz SC, Ryan K, Ahmed N, Plitas G, Chaudhry UI, Kingham TP, et al. Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis. J Immunol 2011;187:1150-6.
    • (2011) J Immunol , vol.187 , pp. 1150-1156
    • Katz, S.C.1    Ryan, K.2    Ahmed, N.3    Plitas, G.4    Chaudhry, U.I.5    Kingham, T.P.6
  • 11
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptormodified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptormodified T cells in chronic lymphoid leukemia. N Engl J Med 2011;365:725-33.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 12
    • 65249101637 scopus 로고    scopus 로고
    • The promise and potential pitfalls of chimeric antigen receptors
    • Sadelain M, Brentjens R, Riviere I. The promise and potential pitfalls of chimeric antigen receptors. Curr Opin Immunol 2009;21:215-23.
    • (2009) Curr Opin Immunol , vol.21 , pp. 215-223
    • Sadelain, M.1    Brentjens, R.2    Riviere, I.3
  • 14
  • 15
    • 84892445176 scopus 로고    scopus 로고
    • Advanced generation anti-prostate specific membrane antigen designer T cells for prostate cancer immunotherapy
    • Ma Q, Gomes EM, Lo AS, Junghans RP. Advanced generation anti-prostate specific membrane antigen designer T cells for prostate cancer immunotherapy. Prostate 2014;74:286-96.
    • (2014) Prostate , vol.74 , pp. 286-296
    • Ma, Q.1    Gomes, E.M.2    Lo, A.S.3    Junghans, R.P.4
  • 16
    • 33846657219 scopus 로고    scopus 로고
    • Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers
    • Blumenthal RD, Leon E, Hansen HJ, Goldenberg DM. Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers. BMC Cancer 2007;7:2.
    • (2007) BMC Cancer , vol.7 , pp. 2
    • Blumenthal, R.D.1    Leon, E.2    Hansen, H.J.3    Goldenberg, D.M.4
  • 17
    • 0021917578 scopus 로고
    • CEA tissue staining in colorectal cancer patients. A way to improve the usefulness of serial serum CEA evaluation
    • Midiri G, Amanti C, Benedetti M, Campisi C, Santeusanio G, Castagna G, et al. CEA tissue staining in colorectal cancer patients. A way to improve the usefulness of serial serum CEA evaluation. Cancer 1985;55:2624-9.
    • (1985) Cancer , vol.55 , pp. 2624-2629
    • Midiri, G.1    Amanti, C.2    Benedetti, M.3    Campisi, C.4    Santeusanio, G.5    Castagna, G.6
  • 18
    • 58149331194 scopus 로고    scopus 로고
    • Second-generation anti-carcinoembryonic antigen designer T cells resist activation-induced cell death, proliferate on tumor contact, secrete cytokines, and exhibit superior antitumor activity in vivo: A preclinical evaluation
    • Emtage PC, Lo AS, Gomes EM, Liu DL, Gonzalo-Daganzo RM, Junghans RP. Second-generation anti-carcinoembryonic antigen designer T cells resist activation-induced cell death, proliferate on tumor contact, secrete cytokines, and exhibit superior antitumor activity in vivo: a preclinical evaluation. Clin Cancer Res 2008;14:8112-22.
    • (2008) Clin Cancer Res , vol.14 , pp. 8112-8122
    • Emtage, P.C.1    Lo, A.S.2    Gomes, E.M.3    Liu, D.L.4    Gonzalo-Daganzo, R.M.5    Junghans, R.P.6
  • 19
    • 79952187823 scopus 로고    scopus 로고
    • T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
    • Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther 2011;19:620-6.
    • (2011) Mol Ther , vol.19 , pp. 620-626
    • Parkhurst, M.R.1    Yang, J.C.2    Langan, R.C.3    Dudley, M.E.4    Nathan, D.A.5    Feldman, S.A.6
  • 20
    • 70249149719 scopus 로고    scopus 로고
    • Conversion to resectability using hepatic artery infusion plus systemic chemotherapy for the treatment of unresectable liver metastases from colorectal carcinoma
    • Kemeny NE, Melendez FD, Capanu M, Paty PB, Fong Y, Schwartz LH, et al. Conversion to resectability using hepatic artery infusion plus systemic chemotherapy for the treatment of unresectable liver metastases from colorectal carcinoma. J Clin Oncol 2009;27:3465-71.
    • (2009) J Clin Oncol , vol.27 , pp. 3465-3471
    • Kemeny, N.E.1    Melendez, F.D.2    Capanu, M.3    Paty, P.B.4    Fong, Y.5    Schwartz, L.H.6
  • 21
    • 0028053067 scopus 로고
    • Regional adoptive immunotherapy with interleukin-2 and lymphokineactivated killer (LAK) cells for liver metastases
    • Keilholz U, Scheibenbogen C, Brado M, Georgi P, Maclachlan D, Brado B, et al. Regional adoptive immunotherapy with interleukin-2 and lymphokineactivated killer (LAK) cells for liver metastases. Eur J Cancer 1994;30A:103-5.
    • (1994) Eur J Cancer , vol.30 A , pp. 103-105
    • Keilholz, U.1    Scheibenbogen, C.2    Brado, M.3    Georgi, P.4    Maclachlan, D.5    Brado, B.6
  • 22
    • 0033987888 scopus 로고    scopus 로고
    • Effect of intraportal adoptive immunotherapy on liver metastases after resection of pancreatic cancer
    • Kobari M, Egawa S, Shibuya K, Sunamura M, Saitoh K, Matsuno S. Effect of intraportal adoptive immunotherapy on liver metastases after resection of pancreatic cancer. Br J Surg 2000;87:43-8.
    • (2000) Br J Surg , vol.87 , pp. 43-48
    • Kobari, M.1    Egawa, S.2    Shibuya, K.3    Sunamura, M.4    Saitoh, K.5    Matsuno, S.6
  • 23
    • 0025283158 scopus 로고
    • Transcatheter arterial injection of autologous lymphokine-activated killer (LAK) cells into patients with liver cancers
    • Komatsu T, Yamauchi K, Furukawa T, Obata H. Transcatheter arterial injection of autologous lymphokine-activated killer (LAK) cells into patients with liver cancers. J Clin Immunol 1990;10:167-74.
    • (1990) J Clin Immunol , vol.10 , pp. 167-174
    • Komatsu, T.1    Yamauchi, K.2    Furukawa, T.3    Obata, H.4
  • 24
  • 26
    • 73149092567 scopus 로고    scopus 로고
    • Guidelines for the evaluation of immune therapy activity in solid tumors: Immune-related response criteria
    • Wolchok JD, Hoos A, O'Day S, Weber JS, Hamid O, Lebbe C, et al. Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria. Clin Cancer Res 2009;15:7412-20.
    • (2009) Clin Cancer Res , vol.15 , pp. 7412-7420
    • Wolchok, J.D.1    Hoos, A.2    O'Day, S.3    Weber, J.S.4    Hamid, O.5    Lebbe, C.6
  • 27
    • 39149094919 scopus 로고    scopus 로고
    • Sorting vector producer cells for high transgene expression increases retroviral titer
    • Beaudoin EL, Bais AJ, Junghans RP. Sorting vector producer cells for high transgene expression increases retroviral titer. J Virol Methods 2008;148:253-9.
    • (2008) J Virol Methods , vol.148 , pp. 253-259
    • Beaudoin, E.L.1    Bais, A.J.2    Junghans, R.P.3
  • 28
    • 37149001207 scopus 로고    scopus 로고
    • Multifactorial optimization of gammaretroviral gene transfer into human T lymphocytes for clinical application
    • Quintas-Cardama A, Yeh RK, Hollyman D, Stefanski J, Taylor C, Nikhamin Y, et al. Multifactorial optimization of gammaretroviral gene transfer into human T lymphocytes for clinical application. Hum Gene Ther 2007;18:1253-60.
    • (2007) Hum Gene Ther , vol.18 , pp. 1253-1260
    • Quintas-Cardama, A.1    Yeh, R.K.2    Hollyman, D.3    Stefanski, J.4    Taylor, C.5    Nikhamin, Y.6
  • 29
    • 84897814382 scopus 로고    scopus 로고
    • Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay
    • Karimi MA, Lee E, Bachmann MH, Salicioni AM, Behrens EM, Kambayashi T, et al. Measuring cytotoxicity by bioluminescence imaging outperforms the standard chromium-51 release assay. PLoS ONE 2014;9:e89357.
    • (2014) PLoS ONE , vol.9 , pp. e89357
    • Karimi, M.A.1    Lee, E.2    Bachmann, M.H.3    Salicioni, A.M.4    Behrens, E.M.5    Kambayashi, T.6
  • 30
    • 0035869493 scopus 로고    scopus 로고
    • Biventricular cardiac thrombosis during interleukin-2 infusion
    • Junghans RP, Manning W, Safar M, Quist W. Biventricular cardiac thrombosis during interleukin-2 infusion. N Engl J Med 2001;344:859-60.
    • (2001) N Engl J Med , vol.344 , pp. 859-860
    • Junghans, R.P.1    Manning, W.2    Safar, M.3    Quist, W.4
  • 31
    • 37649015497 scopus 로고    scopus 로고
    • Meta-analysis of hepatic arterial infusion for unresectable liver metastases from colorectal cancer: The end of an era?
    • Mocellin S, Pilati P, Lise M, Nitti D. Meta-analysis of hepatic arterial infusion for unresectable liver metastases from colorectal cancer: the end of an era? J Clin Oncol 2007;25:5649-54.
    • (2007) J Clin Oncol , vol.25 , pp. 5649-5654
    • Mocellin, S.1    Pilati, P.2    Lise, M.3    Nitti, D.4
  • 32
    • 0034596475 scopus 로고    scopus 로고
    • Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: A randomised trial
    • Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, et al. Adoptive immunotherapy to lower postsurgical recurrence rates of hepatocellular carcinoma: a randomised trial. Lancet 2000;356:802-7.
    • (2000) Lancet , vol.356 , pp. 802-807
    • Takayama, T.1    Sekine, T.2    Makuuchi, M.3    Yamasaki, S.4    Kosuge, T.5    Yamamoto, J.6
  • 33
    • 0032976897 scopus 로고    scopus 로고
    • Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b
    • Rosenberg SA, Yang JC, Schwartzentruber DJ, Hwu P, Marincola FM, Topalian SL, et al. Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b. J Clin Oncol 1999;17:968-75.
    • (1999) J Clin Oncol , vol.17 , pp. 968-975
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3    Hwu, P.4    Marincola, F.M.5    Topalian, S.L.6
  • 34
    • 77952361779 scopus 로고    scopus 로고
    • Anti-GD3 chimeric sFv-CD28/Tcell receptor zeta designer T cells for treatment of metastatic melanoma and other neuroectodermal tumors
    • Lo AS, Ma Q, Liu DL, Junghans RP. Anti-GD3 chimeric sFv-CD28/Tcell receptor zeta designer T cells for treatment of metastatic melanoma and other neuroectodermal tumors. Clin Cancer Res 2010;16:2769-80.
    • (2010) Clin Cancer Res , vol.16 , pp. 2769-2780
    • Lo, A.S.1    Ma, Q.2    Liu, D.L.3    Junghans, R.P.4
  • 35
    • 84888373513 scopus 로고    scopus 로고
    • Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis
    • Bramswig KH, Poettler M, Unseld M, Wrba F, Uhrin P, Zimmermann W, et al. Soluble carcinoembryonic antigen activates endothelial cells and tumor angiogenesis. Cancer Res 2013;73:6584-96.
    • (2013) Cancer Res , vol.73 , pp. 6584-6596
    • Bramswig, K.H.1    Poettler, M.2    Unseld, M.3    Wrba, F.4    Uhrin, P.5    Zimmermann, W.6
  • 36
    • 0026322143 scopus 로고
    • Distribution and therapeutic effect of intraarterially transferred tumorinfiltrating lymphocytes in hepatic malignancies. A preliminary report
    • Takayama T, Makuuchi M, Sekine T, Terui S, Shiraiwa H, Kosuge T, et al. Distribution and therapeutic effect of intraarterially transferred tumorinfiltrating lymphocytes in hepatic malignancies. A preliminary report. Cancer 1991;68:2391-6.
    • (1991) Cancer , vol.68 , pp. 2391-2396
    • Takayama, T.1    Makuuchi, M.2    Sekine, T.3    Terui, S.4    Shiraiwa, H.5    Kosuge, T.6
  • 37
    • 84892963061 scopus 로고    scopus 로고
    • Tracking gene and cell fate for therapeutic gain
    • Kooreman NG, Ransohoff JD, Wu JC. Tracking gene and cell fate for therapeutic gain. Nat Mater 2014;13:106-9.
    • (2014) Nat Mater , vol.13 , pp. 106-109
    • Kooreman, N.G.1    Ransohoff, J.D.2    Wu, J.C.3
  • 38
    • 84927173944 scopus 로고    scopus 로고
    • Neutrophil: Lymphocyte ratios and serum cytokine changes after hepatic artery chimeric antigen receptor-modified T-cell infusions for liver metastases
    • Saied A, Licata L, Burga RA, Thorn M, McCormack E, Stainken BF, et al. Neutrophil: lymphocyte ratios and serum cytokine changes after hepatic artery chimeric antigen receptor-modified T-cell infusions for liver metastases. Cancer Gene Ther 2014;21:457-62.
    • (2014) Cancer Gene Ther , vol.21 , pp. 457-462
    • Saied, A.1    Licata, L.2    Burga, R.A.3    Thorn, M.4    McCormack, E.5    Stainken, B.F.6
  • 39
    • 0027198722 scopus 로고
    • Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen
    • Hansen HJ, Goldenberg DM, Newman ES, Grebenau R, Sharkey RM. Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen. Cancer 1993;71:3478-85.
    • (1993) Cancer , vol.71 , pp. 3478-3485
    • Hansen, H.J.1    Goldenberg, D.M.2    Newman, E.S.3    Grebenau, R.4    Sharkey, R.M.5
  • 40
    • 34447530843 scopus 로고    scopus 로고
    • Antibodybased therapies for cancer
    • Chabner BA, Longo DL, editors, 4th ed; Lippincott, Williams, and Wilkins; Philadelphia, PA
    • Scheinberg DB, Mulford DA, Jurcic JG, Sgouros G, Junghans RP. Antibodybased therapies for cancer. In: Chabner BA, Longo DL, editors. Cancer Chemotherapy and Biotherapy. 4th ed; Lippincott, Williams, and Wilkins; Philadelphia, PA, 2006. p. 666-98.
    • (2006) Cancer Chemotherapy and Biotherapy , pp. 666-698
    • Scheinberg, D.B.1    Mulford, D.A.2    Jurcic, J.G.3    Sgouros, G.4    Junghans, R.P.5
  • 41
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R, Hughes MS, Royal R, Kammula U, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J Clin Oncol 2008;26:5233-9.
    • (2008) J Clin Oncol , vol.26 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3    Hughes, M.S.4    Royal, R.5    Kammula, U.6
  • 42
    • 0022387502 scopus 로고
    • In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2
    • Lotze MT, Matory YL, Ettinghausen SE, Rayner AA, Sharrow SO, Seipp CA, et al. In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2. J Immunol 1985;135:2865-75.
    • (1985) J Immunol , vol.135 , pp. 2865-2875
    • Lotze, M.T.1    Matory, Y.L.2    Ettinghausen, S.E.3    Rayner, A.A.4    Sharrow, S.O.5    Seipp, C.A.6
  • 44
    • 1642495750 scopus 로고    scopus 로고
    • Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition
    • Pillarisetty VG, Shah AB, Miller G, Bleier JI, De Matteo RP. Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition. J Immunol 2004;172:1009-17.
    • (2004) J Immunol , vol.172 , pp. 1009-1017
    • Pillarisetty, V.G.1    Shah, A.B.2    Miller, G.3    Bleier, J.I.4    De Matteo, R.P.5
  • 47
    • 32644448488 scopus 로고    scopus 로고
    • A phase 1 trial of donor lymphocyte infusions expanded and activated ex vivo via CD3/CD28 costimulation
    • Porter DL, Levine BL, Bunin N, Stadtmauer EA, Luger SM, Goldstein S, et al. A phase 1 trial of donor lymphocyte infusions expanded and activated ex vivo via CD3/CD28 costimulation. Blood 2006;107:1325-31.
    • (2006) Blood , vol.107 , pp. 1325-1331
    • Porter, D.L.1    Levine, B.L.2    Bunin, N.3    Stadtmauer, E.A.4    Luger, S.M.5    Goldstein, S.6


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