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Volumn 62, Issue 5, 2016, Pages 1511-1531

An analytics approach to designing combination chemotherapy regimens for cancer

Author keywords

Healthcare; Integer; Programming; Simulation; Statistics; Treatment

Indexed keywords

ARTIFICIAL INTELLIGENCE; CHEMOTHERAPY; DISEASES; FORECASTING; HEALTH CARE; INTEGER PROGRAMMING; LEARNING SYSTEMS; MATHEMATICAL PROGRAMMING; QUALITY CONTROL; STATISTICS; TOXICITY;

EID: 84968779588     PISSN: 00251909     EISSN: 15265501     Source Type: Journal    
DOI: 10.1287/mnsc.2015.2363     Document Type: Article
Times cited : (91)

References (56)
  • 1
    • 77951888102 scopus 로고    scopus 로고
    • Multicenter phase III comparison of cisplatin/S-1 with cisplatin/ infusional fluorouracil in advanced gastric or gastroesophageal adenocarcinoma study: The FLAGS trial
    • Ajani J, Rodriguez W, Bodoky G, Moiseyenko V, Lichinitser M, Gorbunova V, Vynnychenko I, Garin A, Lang I, Falcon S (2010) Multicenter phase III comparison of cisplatin/S-1 with cisplatin/ infusional fluorouracil in advanced gastric or gastroesophageal adenocarcinoma study: The FLAGS trial. J. Clinical Oncology 28(9):1547-1553.
    • (2010) J. Clinical Oncology , vol.28 , Issue.9 , pp. 1547-1553
    • Ajani, J.1    Rodriguez, W.2    Bodoky, G.3    Moiseyenko, V.4    Lichinitser, M.5    Gorbunova, V.6    Vynnychenko, I.7    Garin, A.8    Lang, I.9    Falcon, S.10
  • 2
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • Bang Y-J, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick, F, et al. (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial. Lancet 376(9742):687-697.
    • (2010) Lancet , vol.376 , Issue.9742 , pp. 687-697
    • Bang, Y.-J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5    Sawaki, A.6    Lordick, F.7
  • 3
    • 0035478854 scopus 로고    scopus 로고
    • Random forests
    • Breiman L (2001) Random forests. Machine Learn. 45(1):5-32.
    • (2001) Machine Learn , vol.45 , Issue.1 , pp. 5-32
    • Breiman, L.1
  • 4
    • 0030176378 scopus 로고    scopus 로고
    • Karnofsky and ECOG performance status scoring in lung cancer: A prospective, longitudinal study of 536 patients from a single institution
    • Buccheri G, Ferrigno D, Tamburini M (1996) Karnofsky and ECOG performance status scoring in lung cancer: A prospective, longitudinal study of 536 patients from a single institution. Eur. J. Cancer 32(7):1135-1141.
    • (1996) Eur. J. Cancer , vol.32 , Issue.7 , pp. 1135-1141
    • Buccheri, G.1    Ferrigno, D.2    Tamburini, M.3
  • 5
    • 0031047117 scopus 로고    scopus 로고
    • Artificial neural networks improve the accuracy of cancer survival prediction
    • Burke H (1997) Artificial neural networks improve the accuracy of cancer survival prediction. Cancer 79(4):857-862.
    • (1997) Cancer , vol.79 , Issue.4 , pp. 857-862
    • Burke, H.1
  • 7
    • 33745960387 scopus 로고    scopus 로고
    • An open, multi-centre, phase II clinical trial to evaluate the efficacy and safety of paclitaxel, UFT, and leucovorin in patients with advanced gastric cancer
    • Chao Y, Li CP, Chao TY, Su WC, Hsieh RK, Wu MF, Yeh KH, Kao WY, Chen LT, Cheng AL (2006) An open, multi-centre, phase II clinical trial to evaluate the efficacy and safety of paclitaxel, UFT, and leucovorin in patients with advanced gastric cancer. British J. Cancer 95(2):159-163.
    • (2006) British J. Cancer , vol.95 , Issue.2 , pp. 159-163
    • Chao, Y.1    Li, C.P.2    Chao, T.Y.3    Su, W.C.4    Hsieh, R.K.5    Wu, M.F.6    Yeh, K.H.7    Kao, W.Y.8    Chen, L.T.9    Cheng, A.L.10
  • 8
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • Chou T-C (2006) Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacological Rev. 58(3):621-681.
    • (2006) Pharmacological Rev , vol.58 , Issue.3 , pp. 621-681
    • Chou, T.-C.1
  • 10
    • 0031619316 scopus 로고    scopus 로고
    • Bayesian Q-learning
    • (AAAI Press, Palo Alto, CA)
    • Dearden R, Friedman N, Russell S (1998) Bayesian Q-learning. AAAI-98 Proc. (AAAI Press, Palo Alto, CA), 761-768.
    • (1998) AAAI-98 Proc , pp. 761-768
    • Dearden, R.1    Friedman, N.2    Russell, S.3
  • 11
    • 3242803674 scopus 로고    scopus 로고
    • Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: A meta-analysis
    • Delbaldo C, Michiels S, Syz N, Soria JC, Le Chevalier T, Pignon JP (2004) Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: A meta-analysis. J. Amer. Medical Assoc. 292(4):470-484.
    • (2004) J. Amer. Medical Assoc , vol.292 , Issue.4 , pp. 470-484
    • Delbaldo, C.1    Michiels, S.2    Syz, N.3    Soria, J.C.4    Le Chevalier, T.5    Pignon, J.P.6
  • 12
    • 19344364327 scopus 로고    scopus 로고
    • Predicting breast cancer survivability: A comparison of three data mining methods
    • Delen D, Walker G, Kadam A (2005) Predicting breast cancer survivability: A comparison of three data mining methods. Artificial Intelligence Medicine 34(2):113-127.
    • (2005) Artificial Intelligence Medicine , vol.34 , Issue.2 , pp. 113-127
    • Delen, D.1    Walker, G.2    Kadam, A.3
  • 13
    • 15244341760 scopus 로고    scopus 로고
    • Predicting the outcome of phase III trials using phase II data: A case study of clinical trial simulation in late stage drug development
    • De Ridder F (2005) Predicting the outcome of phase III trials using phase II data: A case study of clinical trial simulation in late stage drug development. Basic Clinical Pharmacology Toxicology 96(3):235-241.
    • (2005) Basic Clinical Pharmacology Toxicology , vol.96 , Issue.3 , pp. 235-241
    • De Ridder, F.1
  • 14
    • 21344453004 scopus 로고    scopus 로고
    • Pharmacogenetics for individualized cancer chemotherapy
    • Efferth T, Volm M (2005) Pharmacogenetics for individualized cancer chemotherapy. Pharmacology Therapeutics 107(2):155-176.
    • (2005) Pharmacology Therapeutics , vol.107 , Issue.2 , pp. 155-176
    • Efferth, T.1    Volm, M.2
  • 15
    • 55549135706 scopus 로고    scopus 로고
    • A knowledge-gradient policy for sequential information collection
    • Frazier PI, Powell WB, Dayanik S (2008) A knowledge-gradient policy for sequential information collection. SIAM J. Control Optim. 47(5):2410-2439.
    • (2008) SIAM J. Control Optim , vol.47 , Issue.5 , pp. 2410-2439
    • Frazier, P.I.1    Powell, W.B.2    Dayanik, S.3
  • 16
    • 77950537175 scopus 로고    scopus 로고
    • Regularization paths for generalized linear models via coordinate descent
    • Friedman J, Hastie T, Tibshirani R (2010a) Regularization paths for generalized linear models via coordinate descent. J. Statist. Software 33(1):1-22.
    • (2010) J. Statist. Software , vol.33 , Issue.1 , pp. 1-22
    • Friedman, J.1    Hastie, T.2    Tibshirani, R.3
  • 20
    • 84942484786 scopus 로고
    • Ridge regression: Biased estimation for nonorthogonal problems
    • Hoerl AE, Kennard RW (1970) Ridge regression: Biased estimation for nonorthogonal problems. Technometrics 12(1):55-67.
    • (1970) Technometrics , vol.12 , Issue.1 , pp. 55-67
    • Hoerl, A.E.1    Kennard, R.W.2
  • 21
    • 84865424450 scopus 로고    scopus 로고
    • Geographic difference in safety and efficacy of systemic chemotherapy for advanced gastric or gastroesophageal carcinoma: A meta-analysis and meta-regression
    • Hsu C, Shen Y-C, Cheng C-C, Cheng AL, Hu FC, Yeh KH (2012) Geographic difference in safety and efficacy of systemic chemotherapy for advanced gastric or gastroesophageal carcinoma: A meta-analysis and meta-regression. Gastric Cancer 15(3): 265-280.
    • (2012) Gastric Cancer , vol.15 , Issue.3 , pp. 265-280
    • Hsu, C.1    Shen, Y.-C.2    Cheng, C.-C.3    Cheng, A.L.4    Hu, F.C.5    Yeh, K.H.6
  • 22
    • 4944228528 scopus 로고    scopus 로고
    • Technical report, Department of Computer Science, National Taiwan University. Accessed June 4, 2013
    • Hsu C-W, Chang C-C, Lin C-J (2003) A practical guide to support vector classification. Technical report, Department of Computer Science, National Taiwan University. Accessed June 4, 2013, http://www.csie.ntu.edu.tw/~cjlin/papers/guide/guide.pdf.
    • (2003) A Practical Guide to Support Vector Classification
    • Hsu, C.-W.1    Chang, C.-C.2    Lin, C.-J.3
  • 24
    • 79958052494 scopus 로고    scopus 로고
    • A phase II multicenter study of triple therapy with paclitaxel, S-1 and cisplatin in patients with advanced gastric cancer
    • Iwase H, Shimada M, Tsuzuki T, Ina K, Sugihara M, Haruta J, Shinoda M, Kumada T, Goto H (2011) A phase II multicenter study of triple therapy with paclitaxel, S-1 and cisplatin in patients with advanced gastric cancer. Oncology 80(1-2): 76-83.
    • (2011) Oncology , vol.80 , Issue.1-2 , pp. 76-83
    • Iwase, H.1    Shimada, M.2    Tsuzuki, T.3    Ina, K.4    Sugihara, M.5    Haruta, J.6    Shinoda, M.7    Kumada, T.8    Goto, H.9
  • 25
    • 0030951433 scopus 로고    scopus 로고
    • Comparison of a genetic algorithm neural network with logistic regression for predicting outcome after surgery for patients with nonsmall cell lung carcinoma
    • Jefferson M, Pendleton N, Lucas S, Horan MA (1997) Comparison of a genetic algorithm neural network with logistic regression for predicting outcome after surgery for patients with nonsmall cell lung carcinoma. Cancer 79(7):1338-1342.
    • (1997) Cancer , vol.79 , Issue.7 , pp. 1338-1342
    • Jefferson, M.1    Pendleton, N.2    Lucas, S.3    Horan, M.A.4
  • 26
    • 63749118193 scopus 로고    scopus 로고
    • Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: A randomised phase III noninferiority trial
    • Kang Y-K, Kang W-K, Shin D-B, Chen J, Xiong J, Wang J, Lichinitser M, et al. (2009) Capecitabine/cisplatin versus 5-fluorouracil/cisplatin as first-line therapy in patients with advanced gastric cancer: A randomised phase III noninferiority trial. Ann. Oncology 20(4):666-673.
    • (2009) Ann. Oncology , vol.20 , Issue.4 , pp. 666-673
    • Kang, Y.-K.1    Kang, W.-K.2    Shin, D.-B.3    Chen, J.4    Xiong, J.5    Wang, J.6    Lichinitser, M.7
  • 27
    • 0002391815 scopus 로고
    • The clinical evaluation of chemotherapeutic agents in cancer
    • MacLeod CM, ed., (Columbia University Press, New York)
    • Karnofsky DA, Burchenal JH (1949) The clinical evaluation of chemotherapeutic agents in cancer. MacLeod CM, ed. Evaluation of Chemotherapeutic Agents (Columbia University Press, New York), 191-205.
    • (1949) Evaluation of Chemotherapeutic Agents , pp. 191-205
    • Karnofsky, D.A.1    Burchenal, J.H.2
  • 28
    • 72249115598 scopus 로고    scopus 로고
    • Use of virtual patient populations for rescuing discontinued drug candidates and for reducing the number of patients in clinical trials
    • Kleiman M, Sagi Y, Bloch N, Agur Z (2009) Use of virtual patient populations for rescuing discontinued drug candidates and for reducing the number of patients in clinical trials. Alternatives Lab Animals 37(Supplement 1):39-45.
    • (2009) Alternatives Lab Animals , vol.37 , pp. 39-45
    • Kleiman, M.1    Sagi, Y.2    Bloch, N.3    Agur, Z.4
  • 29
    • 40749153540 scopus 로고    scopus 로고
    • S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): A phase III trial
    • Koizumi W, Narahara H, Hara T, Takagane A, Akiya T, Takagi M, Miyashita K, et al. (2008) S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): A phase III trial. Lancet 9(3):215-221.
    • (2008) Lancet , vol.9 , Issue.3 , pp. 215-221
    • Koizumi, W.1    Narahara, H.2    Hara, T.3    Takagane, A.4    Akiya, T.5    Takagi, M.6    Miyashita, K.7
  • 30
    • 75149192630 scopus 로고    scopus 로고
    • Randomized, multicenter, phase III trial of heptaplatin 1-hour infusion and 5-fluorouracil combination chemotherapy comparing with cisplatin and 5-fluorouracil combination chemotherapy in patients with advanced gastric cancer
    • Lee KH, Hyun MS, Kim H-K, Jin HM, Yang J, Song HS, Do YR, et al. (2009) Randomized, multicenter, phase III trial of heptaplatin 1-hour infusion and 5-fluorouracil combination chemotherapy comparing with cisplatin and 5-fluorouracil combination chemotherapy in patients with advanced gastric cancer. Cancer Res. Treatment 41(1):12-18.
    • (2009) Cancer Res. Treatment , vol.41 , Issue.1 , pp. 12-18
    • Lee, K.H.1    Hyun, M.S.2    Kim, H.-K.3    Jin, H.M.4    Yang, J.5    Song, H.S.6    Do, Y.R.7
  • 31
    • 0037391605 scopus 로고    scopus 로고
    • Survival-time classification of breast cancer patients
    • Lee Y-J, Mangasarian OL, Wolberg WH (2003) Survival-time classification of breast cancer patients. Comput. Optim. Appl. 25(1):151-166.
    • (2003) Comput. Optim. Appl , vol.25 , Issue.1 , pp. 151-166
    • Lee, Y.-J.1    Mangasarian, O.L.2    Wolberg, W.H.3
  • 32
    • 0345040873 scopus 로고    scopus 로고
    • Classification and regression by random - Forest
    • Liaw A, Wiener M (2002) Classification and regression by random- Forest. R News 2(3):18-22. http://CRAN.R-project.org/doc/ Rnews/.
    • (2002) R News , vol.2 , Issue.3 , pp. 18-22
    • Liaw, A.1    Wiener, M.2
  • 33
    • 34447255242 scopus 로고    scopus 로고
    • Weekly infusional high-dose fluorouracil (HD-FU), HD-FU plus folinic acid (HD-FU/FA), or HD-FU/FA plus biweekly cisplatin in advanced gastric cancer: Randomized phase II trial 40,953 of the European organisation for research and treatment of cancer gastrointestinal group and the arbeitsgemeinschaft internistische onkologie
    • Lutz MP, Wilke H, Wagener DJT, Vanhoefer U, Jeziorski K, Hegewisch- Becker S, Balleisen L, et al. (2007) Weekly infusional high-dose fluorouracil (HD-FU), HD-FU plus folinic acid (HD-FU/FA), or HD-FU/FA plus biweekly cisplatin in advanced gastric cancer: Randomized phase II trial 40,953 of the European organisation for research and treatment of cancer gastrointestinal group and the arbeitsgemeinschaft internistische onkologie. J. Clinical Oncology 25(18):2580-2585.
    • (2007) J. Clinical Oncology , vol.25 , Issue.18 , pp. 2580-2585
    • Lutz, M.P.1    Wilke, H.2    Wagener, D.J.T.3    Vanhoefer, U.4    Jeziorski, K.5    Hegewisch- Becker, S.6    Balleisen, L.7
  • 36
    • 84968702876 scopus 로고    scopus 로고
    • Version 1.2014 (NCCN, Fort Washington, PA). Accessed October 15, 2014
    • NCCN (National Comprehensive Cancer Network) (2014) NCCN Guidelines for Gastric Cancer, Version 1.2014 (NCCN, Fort Washington, PA). Accessed October 15, 2014, http://www.nccn.org/ professionals/physician-gls/pdf/gastric.pdf.
    • (2014) NCCN Guidelines for Gastric Cancer
  • 37
    • 0035551937 scopus 로고    scopus 로고
    • Modeling medical prognosis: Survival analysis techniques
    • Ohno-Machado L (2001) Modeling medical prognosis: Survival analysis techniques. J. Biomedical Informatics 34(6):428-439.
    • (2001) J. Biomedical Informatics , vol.34 , Issue.6 , pp. 428-439
    • Ohno-Machado, L.1
  • 39
    • 0037441965 scopus 로고    scopus 로고
    • Combination chemotherapy for metastatic breast cancer: Reaching for the cure
    • Overmoyer B (2003) Combination chemotherapy for metastatic breast cancer: Reaching for the cure. J. Clinical Oncology 21(4): 580-582.
    • (2003) J. Clinical Oncology , vol.21 , Issue.4 , pp. 580-582
    • Overmoyer, B.1
  • 41
    • 65549115157 scopus 로고    scopus 로고
    • Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment
    • Phan J, Moffitt R, Stokes T, Liu J, Young AN, Nie S, Wang MD (2009) Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment. Trends Biotech. 27(6):350-358.
    • (2009) Trends Biotech , vol.27 , Issue.6 , pp. 350-358
    • Phan, J.1    Moffitt, R.2    Stokes, T.3    Liu, J.4    Young, A.N.5    Nie, S.6    Wang, M.D.7
  • 42
  • 44
    • 0037295092 scopus 로고    scopus 로고
    • Chemotherapy in gastric cancer: A never ending saga
    • Roth AD (2003) Chemotherapy in gastric cancer: A never ending saga. Ann. Oncology 14(2):175-177.
    • (2003) Ann. Oncology , vol.14 , Issue.2 , pp. 175-177
    • Roth, A.D.1
  • 46
    • 0037098178 scopus 로고    scopus 로고
    • How should meta-regression analyses be undertaken and interpreted?
    • Thompson S, Higgins J (2002) How should meta-regression analyses be undertaken and interpreted? Statist. Medicine 21(11): 1559-1573.
    • (2002) Statist. Medicine , vol.21 , Issue.11 , pp. 1559-1573
    • Thompson, S.1    Higgins, J.2
  • 48
    • 85194972808 scopus 로고    scopus 로고
    • Regression shrinkage and selection via the Lasso
    • Tibshirani RJ (1996) Regression shrinkage and selection via the Lasso. J. Roy. Statist. Soc. Ser. B 58(1):267-288.
    • (1996) J. Roy. Statist. Soc. Ser. B , vol.58 , Issue.1 , pp. 267-288
    • Tibshirani, R.J.1
  • 50
    • 41649114164 scopus 로고    scopus 로고
    • Enabling personalized cancer medicine through analysis of gene-expression patterns
    • van't Veer LJ, Bernards R (2008) Enabling personalized cancer medicine through analysis of gene-expression patterns. Nature 452(7187):564-570.
    • (2008) Nature , vol.452 , Issue.7187 , pp. 564-570
    • Van'T Veer, L.J.1    Bernards, R.2
  • 51
    • 33745547767 scopus 로고    scopus 로고
    • Chemotherapy in advanced gastric cancer: A systematic review and meta-analysis based on aggregate data
    • Wagner A (2006) Chemotherapy in advanced gastric cancer: A systematic review and meta-analysis based on aggregate data. J. Clinical Oncology 24(18):2903-2909.
    • (2006) J. Clinical Oncology , vol.24 , Issue.18 , pp. 2903-2909
    • Wagner, A.1
  • 52
    • 63749105563 scopus 로고    scopus 로고
    • Optimising treatment regimens for the management of advanced gastric cancer
    • Wong R, Cunningham D (2009) Optimising treatment regimens for the management of advanced gastric cancer. Ann. Oncology 20(4):605-608.
    • (2009) Ann. Oncology , vol.20 , Issue.4 , pp. 605-608
    • Wong, R.1    Cunningham, D.2
  • 53
    • 84862743531 scopus 로고    scopus 로고
    • World Health Organization, Geneva
    • World Health Organization (2012) Fact sheets: Cancer. World Health Organization, Geneva.
    • (2012) Fact Sheets: Cancer
  • 54
    • 84890112672 scopus 로고    scopus 로고
    • Effectively selecting a target population for a future comparative study
    • Zhao L, Tian L, Cai T, Claggett B, Wei LJ (2013) Effectively selecting a target population for a future comparative study. J. Amer. Statist. Assoc. 108(502):527-539.
    • (2013) J. Amer. Statist. Assoc , vol.108 , Issue.502 , pp. 527-539
    • Zhao, L.1    Tian, L.2    Cai, T.3    Claggett, B.4    Wei, L.J.5
  • 55
    • 70449449564 scopus 로고    scopus 로고
    • Reinforcement learning design for cancer clinical trials
    • Zhao Y, Kosorok MR, Zeng D (2009) Reinforcement learning design for cancer clinical trials. Statist. Med. 28(26):3294-315.
    • (2009) Statist. Med , vol.28 , Issue.26 , pp. 3294-3315
    • Zhao, Y.1    Kosorok, M.R.2    Zeng, D.3
  • 56
    • 84870657864 scopus 로고    scopus 로고
    • Estimating individualized treatment rules using outcome weighted learning
    • Zhao Y, Zeng D, Rush AJ, Kosorok MR (2012) Estimating individualized treatment rules using outcome weighted learning. J. Amer. Statist. Assoc. 107(499):1106-1118.
    • (2012) J. Amer. Statist. Assoc , vol.107 , Issue.499 , pp. 1106-1118
    • Zhao, Y.1    Zeng, D.2    Rush, A.J.3    Kosorok, M.R.4


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