Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging

ACS Nano

Volumn 10, Issue 4, 2016, Pages 4209-4218

  Han, Liang ^a   Kong, Derek K ^a   Zheng, Ming Qiang ^c   Murikinati, Sasidhar ^a   Ma, Chao ^a   Yuan, Peng ^a   Li, Liyuan ^a   Tian, Daofeng ^a   Cai, Qiang ^a   Ye, Chunlin ^a   Holden, Daniel ^c   Park, June Hee ^a   Gao, Xiaobin ^a   Thomas, Jean Leon ^a   Grutzendler, Jaime ^a   Carson, Richard E ^c   Huang, Yiyun ^c   Piepmeier, Joseph M ^a   Zhou, Jiangbing ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yale University   (United States)

^c YALE UNIVERSITY   (United States)

Author keywords

autocatalytic delivery; blood brain barrier; brain cancer; nanoparticles

Indexed keywords

BLOOD; BRAIN; CHEMOTHERAPY; DISEASES; FEEDBACK; GENE THERAPY; TUMORS;

AUTOCATALYTIC; BLOOD-BRAIN BARRIER; BRAIN CANCER; BRAIN REGIONS; PHARMACOLOGICAL AGENTS; POSITIVE FEEDBACK LOOP; SYSTEMIC DELIVERIES; TRANSCYTOSIS;

NANOPARTICLES;

ANTINEOPLASTIC AGENT; CHLOROTOXIN; DECANOIC ACID DERIVATIVE; ETHANOLAMINE DERIVATIVE; ETHYL SEBACATE; GELATINASE A; N-METHYLDIETHANOLAMINE; NANOPARTICLE; PACLITAXEL; POLYMER; PURINE DERIVATIVE; PYRAZOLE DERIVATIVE; REGADENOSON; SCORPION VENOM;

ANIMAL; BLOOD BRAIN BARRIER; BRAIN TUMOR; C57BL MOUSE; CHEMISTRY; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEM; FEMALE; FLUORESCENCE IMAGING; GENE THERAPY; HUMAN; METABOLISM; MOUSE; PERMEABILITY; TRANSCYTOSIS; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; TUMOR MICROENVIRONMENT; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; CELL LINE, TUMOR; DECANOIC ACIDS; DRUG DELIVERY SYSTEMS; ETHANOLAMINES; FEMALE; GENETIC THERAPY; HETEROGRAFTS; HUMANS; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED C57BL; NANOPARTICLES; OPTICAL IMAGING; PACLITAXEL; PERMEABILITY; POLYMERS; PURINES; PYRAZOLES; SCORPION VENOMS; TRANSCYTOSIS; TUMOR MICROENVIRONMENT;

EID: 84968773501     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b07573     Document Type: Article

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