Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation

Cell Stem Cell

Volumn 19, Issue 2, 2016, Pages 205-216

  Dominguez Brauer, Carmen ^a   Hao, Zhenyue ^a   Elia, Andrew J ^a   Fortin, Jérôme M ^a   Nechanitzky, Robert ^a   Brauer, Patrick M ^b   Sheng, Yi ^c   Mana, Miyeko D ^d   Chio, Iok In Christine ^e   Haight, Jillian ^a   Pollett, Aaron ^f   Cairns, Robert ^a   Tworzyanski, Leanne ^a   Inoue, Satoshi ^a   Reardon, Colin ^g   Marques, Ana ^a   Silvester, Jennifer ^a   Cox, Maureen A ^a   Wakeham, Andrew ^a   Yilmaz, Omer H ^d   Sabatini, David M ^d,h   van Es, Johan H ⁱ   Clevers, Hans ⁱ   Sato, Toshiro ^j   Mak, Tak W ^a   more..

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b Canada   (Canada)

^c YORK UNIVERSITY   (Canada)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e Simons Center for Quantitative Biology   (United States)

^f MOUNT SINAI HOSPITAL   (Canada)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

ⁱ UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^j KEIO UNIVERSITY   (Japan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; EPHRIN RECEPTOR B3; MULE PROTEIN; MYC PROTEIN; PROTEASOME; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; WNT PROTEIN; EPHRIN B3; HUWE1 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL PROLIFERATION; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; HEK293 CELL LINE; HT 29 CELL LINE; IMMUNOHISTOCHEMISTRY; INTESTINAL STEM CELL; INTESTINE CRYPT; INTESTINE VILLUS; LYSOSOME; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEM CELL NICHE; ALLELE; ANIMAL; BIOLOGICAL MODEL; CARCINOGENESIS; COLON POLYPOSIS; COLON TUMOR; CYTOLOGY; DEFICIENCY; ENDOCYTOSIS; GENETICS; HUMAN; INTESTINE; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; WNT SIGNALING PATHWAY;

ADENOMATOUS POLYPOSIS COLI; ALLELES; ANIMALS; CARCINOGENESIS; CELL PROLIFERATION; COLONIC NEOPLASMS; ENDOCYTOSIS; EPHRIN-B3; HEK293 CELLS; HUMANS; INTESTINES; LYSOSOMES; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MUTATION; PANETH CELLS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MYC; STEM CELL NICHE; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; WNT SIGNALING PATHWAY;

EID: 84966668081     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.04.002     Document Type: Article

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