Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation

Neuro-Oncology

Volumn 18, Issue 4, 2016, Pages 507-517

  Xia, Shuli ^a   Lal, Bachchu ^a   Tung, Brian ^a   Wang, Shervin ^a   Goodwin, C Rory ^a   Laterra, John ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

glioblastoma; patient derived GBM neurospheres; TNC; tumor microenvironment

Indexed keywords

FOCAL ADHESION KINASE; LAMININ; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; TEMOZOLOMIDE; TENASCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL FUNCTION; CELL GROWTH; CELL INTERACTION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; DRUG SENSITIVITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; GAIN OF FUNCTION MUTATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MICROGLIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; RAT; REGULATORY MECHANISM; STROMA CELL; TUMOR BLOOD VESSEL ENLARGEMENT; TUMOR CELL; TUMOR GROWTH; TUMOR INVASION; TUMOR MICROENVIRONMENT; TUMOR VOLUME; VASCULAR DISEASE; ANIMAL; BRAIN TUMOR; CANCER STEM CELL; CELL MOTION; CELL PROLIFERATION; DRUG SCREENING; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; LEWIS RAT; METABOLISM; PATHOLOGY; SCID MOUSE; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GLIOBLASTOMA; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, SCID; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; RATS, INBRED LEW; TENASCIN; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84966642201     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nov171     Document Type: Article

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