Delivery of human fibroblast growth factor-1 gene to brain by modified rat brain endothelial cells

Journal of Neurochemistry

Volumn 67, Issue 4, 1996, Pages 1643-1652

  Johnston, P ^b   Nam, M ^a   Hossain, M A ^a   Indurti, R R ^b   Mankowski, J L ^a   Wilson, M A ^a   Laterra, J ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

Cell implantation; Gene therapy; Neurotrophic factors; PC12 cells; Tissue engineering

Indexed keywords

FIBROBLAST GROWTH FACTOR 1; PYRANOSIDE;

ANIMAL CELL; ARTICLE; BRAIN PROTECTION; CELL PROLIFERATION; CHIMERA; ENDOTHELIUM CELL; FIBROBLAST; GENE TARGETING; GENE THERAPY; GENETIC ENGINEERING AND GENE TECHNOLOGY; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; PRIORITY JOURNAL; RAT; REPORTER GENE; VASCULAR ENDOTHELIUM;

ANIMALIA;

EID: 0029788607     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67041643.x     Document Type: Article

References (35)

1. Brumley W. C. (1992) Qualitative analysis of environmental samples for aromatic sulfonic acids by high-performance capillary electrophoresis. J. Chromatogr. 603, 267-272.
2. Burgess W. and Maciag T. (1989) The heparin-binding (fibroblast) growth factor family of proteins. Annu. Rev. Biochem. 58, 575-606.
3. Burgess W. H., Mehlman T., Marshak D. R., Fraser B. A., and Maciag T. (1986) Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor. Proc. Natl. Acad. Sci. USA 83, 7216-7220.
4. 2+ responses to AMPA and NMDA in hippocampal neurons. J. Neurochem. 65, 2525-2536.
5. Cuevas P., Carceller F., and Gimenez-Gallego G. (1995a) Acidic fibroblast growth factor prevents death of spinal cord motoneurons in newborn rats after nerve section. Neurol. Res. 17, 396-399.
6. Cuevas P., Carceller F., and Gimenez-Gallego G. (1995b) Acidic fibroblast growth factor prevents post-axotomy neuronal death of the newborn rat facial nerve. Neurosci. Lett. 197, 183-186.
7. Eckenstein F. P., Shipley G. D., and Nishi R. (1991) Acidic and basic fibroblast growth factors in the nervous system: distribution and differential alteration of levels after injury of central versus peripheral nerve. J. Neurosci. 11, 412-419.
8. Ferry N., Duplessis O., Houssin D., Danos O., and Heard J. (1991) Retroviral-mediated gene transfer into hepatocytes in vivo. Proc. Natl. Acad. Sci. USA 88, 8377-8381.
9. Folkman J. (1996) Tumor angiogenesis and tissue factor. Nature Med. 2, 167-168.
10. Forough R., Zhan X., MacPhee M., Friedman S., Engleka K. A., Sayers T., Wiltrout R. H., and Maciag T. (1993) Differential transforming abilities of non-secreted and secreted forms of human fibroblast growth factor-1. J. Biol. Chem. 268, 2960-2968.
11. Harik S. I., Hritz M. A., and Lamanna J. C. (1995) Hypoxia-induced brain angiogenesis in the adult rat. J. Physiol. (Lond.) 485, 525-530.
12. Karasuyama H. and Melchers F. (1988) Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol. 18, 97-104.
13. Klagsbrun M. and D'Amore P. A. (1991) Regulators of angiogenesis. Annu. Rev. Physiol. 53, 217-239.
14. Ku P. T. and D'Amore P. A. (1995) Regulation of basic fibroblast growth factor (bFGF) gene and protein expression following its release from sublethally injured endothelial cells. J. Cell. Biochem. 58, 328-343.
15. Lal B., Cahan M., Couraud P., Goldstein G., and Laterra J. (1994a) Development of endogenous β-galactosidase and autofluorescence in rat brain microvessels: implications for cell tracking and gene transfer studies. J. Histochem. Cytochem. 42, 953-956.
16. Lal B., Indurti R. R., Couraud P., Goldstein G. W., and Laterra J. (1994b) Endothelial cell implantation and survival within experimental gliomas. Proc. Natl Acad. Sci. USA 91, 9695-9699.
17. Messina L. M., Podrakik R. M., Whitehall T. A., and Ekhterae D. (1992) Adhesion and incorporation of lacZ-transduced endothelial cells into the intact capillary wall in the rat. Proc. Natl. Acad. Sci. USA 89, 12018-12022.
18. Mutoh T., Rudkin B. B., and Guroff G. (1992) Differential responses of the phosphorylation of ribosomal protein S6 to nerve growth factor and epidermal growth factor in PC12 cells. J. Neurochem. 58, 175-185.
19. Nabel E. G., Plautx G., Boyce F. M., and Stanley J. C. (1989) Recombinant gene expression in vivo within endothelial cells of the arterial wall. Science 244, 1342-1344.
20. Nam M., Johnston P., Lal B., Indurti R., Wilson M, A., and Laterra J. (1996) Endothelial cell-based anti-tumor gene delivery to brain. Brain Res. (in press).
21. Netland P. A., Zetter B. R., Via D. P., and Voyta J. C. (1985) In situ labelling of vascular endothelium with fluorescent acetylated low density lipoprotein. Histochem. J. 17, 1309-1320.
22. Nozaki K., Finklestein S. P., and Beal M. F. (1993) Basic fibroblast growth factor protects against hypoxia-ischemia and NMDA neurotoxicity in neonatal rats. J. Cereb. Blood Flow Metab. 13, 221-228.
23. Ojeifo J. O., Forough R., Paik S., Maciag T., and Zwiebel J. A. (1995) Angiogenesis-directed implantation of genetically modified endothelial cells in mice. Cancer Res. 55, 2240-2244.
24. Perkins L. A. and Cain L. D. (1995) Basic fibroblast growth factor (bFGF) increases the survival of embryonic and postnatal basal forebrain cholinergic neurons in primary culture. Int. J. Dev. Neurosci. 13, 51-61.
25. Rak J., Filmus J., Finkenzeller G., Grugel S., Marme D., and Kerbel R. S. (1995) Oncogenes as inducers of tumor angiogenesis. Cancer Metastasis Rev. 14, 263-277.
26. Robertson P. L., Du Bois M., Bowman P. D., and Goldstein G. W. (1985) Angiogenesis in developing rat brain: an in vivo and in vitro study. Dev. Brain Res. 23, 219-223.
27. Rosenstein J. M., Krum J. M., Sternberger L. A., Pulley M. T., and Sternberger N. H. (1992) Immunocytochemical expression of the endothelial barrier antigen (EBA) during brain angiogenesis. Brain Res. Dev. Brain Res. 66, 47-54.
28. Roux F., Durieu-Trautmann O., Chaverot N., Claire M., Mailly P., Bourre J. M., Strosberg A. D., and Couraud P. O. (1994) Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells. J. Cell. Physiol. 159, 101-113.
29. Rydel R. E. and Greene L. A. (1987) Acidic and basic fibroblast growth factors promote stable neunte outgrowth and neuronal differentiation in cultures of PC12 cells. J. Neurosci. 7, 3639-3653.
30. Takayama H., Ray J., Raymon H. K., and Baird A. (1995) Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease. Nature Med. 1, 53-58.
31. Tanaka R., Miyasaka Y., Yada K., Ohwada T., and Kameya T. (1995) Basic fibroblast growth factor increases regional cerebral blood flow and reduces infarct size after experimental ischemia in a rat model. Stroke 26, 2154-2158.
32. Voyta J. C., Via D. P., Butterfield C. E., and Zetter B. R. (1984) Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein. J. Cell Biol. 99, 2034-2040.
33. Wanaka A., Johnson E. M. Jr., and Milbrandt J. (1990) Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization. Neuron 5, 267-281.
34. Wilson J. M., Birinyi L. K., Salomon R. N., Libby P., Callow A. D., and Mulligan R. C. (1989) Implantation of vascular grafts lined with genetically modified endothelial cells. Science 244, 1344-1346.
35. Wisden W., Morris B. J., and Hunt S. P. (1991) In situ hybridization with synthetic DNA probes, in Molecular Neurobiology: A Practical Approach (Chad J. and Wheal H., eds), pp. 205-225. Oxford University Press, New York.