-
1
-
-
0021256895
-
Alzheimer’s disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG, Wong CW. Alzheimer’s disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun (3): 885-90 (1984).
-
(1984)
Biochem Biophys Res Commun
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
2
-
-
0032556859
-
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
De Strooper B, Saftig P, Craessaerts K, Vanderstichele H, Guhde G, Annaert W, et al. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. Nature 391(6665): 387-90 (1998).
-
(1998)
Nature
, vol.391
, Issue.6665
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Guhde, G.5
Annaert, W.6
-
3
-
-
15844394507
-
What is the dominant Abeta species in human brain tissue? A review
-
Gregory GC, Halliday GM. What is the dominant Abeta species in human brain tissue? A review. Neurotox Res 7(1-2): 29-41 (2005).
-
(2005)
Neurotox Res
, vol.7
, Issue.1-2
, pp. 29-41
-
-
Gregory, G.C.1
Halliday, G.M.2
-
4
-
-
0032888131
-
Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer’s disease
-
Lue LF, Kuo YM, Roher AE, Brachova L, Shen Y, Sue L, et al. Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer’s disease. Am J Pathol 155(3): 853-62 (1999).
-
(1999)
Am J Pathol
, vol.155
, Issue.3
, pp. 853-862
-
-
Lue, L.F.1
Kuo, Y.M.2
Roher, A.E.3
Brachova, L.4
Shen, Y.5
Sue, L.6
-
5
-
-
0033358671
-
Early-onset autosomal dominant Alzheimer disease: Prevalence, genetic heterogeneity, and mutation spectrum
-
Campion D, Dumanchin C, Hannequin D, Dubois B, Belliard S, Puel M, et al. Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum. Am J Hum Genet 5(3): 664-70 (1999).
-
(1999)
Am J Hum Genet
, vol.5
, Issue.3
, pp. 664-670
-
-
Campion, D.1
Dumanchin, C.2
Hannequin, D.3
Dubois, B.4
Belliard, S.5
Puel, M.6
-
6
-
-
78650678688
-
Decreased clearance of CNS beta-amyloid in Alzheimer’s disease
-
Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, et al. Decreased clearance of CNS beta-amyloid in Alzheimer’s disease. Science 330(6012): 1774 (2010).
-
(2010)
Science
, vol.330
, Issue.6012
, pp. 1774
-
-
Mawuenyega, K.G.1
Sigurdson, W.2
Ovod, V.3
Munsell, L.4
Kasten, T.5
Morris, J.C.6
-
7
-
-
38149090292
-
The blood-brain barrier in health and chronic neurodegenerative disorders
-
Zlokovic BV. The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron 57(2): 178-201 (2008).
-
(2008)
Neuron
, vol.57
, Issue.2
, pp. 178-201
-
-
Zlokovic, B.V.1
-
8
-
-
84906896658
-
Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging
-
Zhang W, Xiong H, Callaghan D, Liu H, Jones A, Pei K, et al. Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging. Fluids Barriers CNS 10(1):13 (2013).
-
(2013)
Fluids Barriers CNS
, vol.10
, Issue.1
, pp. 13
-
-
Zhang, W.1
Xiong, H.2
Callaghan, D.3
Liu, H.4
Jones, A.5
Pei, K.6
-
9
-
-
84921830931
-
Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease
-
Baranello RJ, Bharani KL, Padmaraju V, Chopra N, Lahiri DK, Greig NH, et al. Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease. Curr Alzheimer Res 12(1): 32-46 (2015).
-
(2015)
Curr Alzheimer Res
, vol.12
, Issue.1
, pp. 32-46
-
-
Baranello, R.J.1
Bharani, K.L.2
Padmaraju, V.3
Chopra, N.4
Lahiri, D.K.5
Greig, N.H.6
-
10
-
-
84893833082
-
Differences in amyloid-beta clearance across mouse and human blood-brain barrier models: Kinetic analysis and mechanistic modeling
-
Qosa H, Abuasal BS, Romero IA, Weksler B, Couraud PO, Keller JN, et al. Differences in amyloid-beta clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling. Neuropharmacology 79: 668-78 (2014).
-
(2014)
Neuropharmacology
, vol.79
, pp. 668-678
-
-
Qosa, H.1
Abuasal, B.S.2
Romero, I.A.3
Weksler, B.4
Couraud, P.O.5
Keller, J.N.6
-
11
-
-
34948888151
-
Clearance of amyloid-beta by circulating lipoprotein receptors
-
Sagare A, Deane R, Bell RD, Johnson B, Hamm K, Pendu R, et al. Clearance of amyloid-beta by circulating lipoprotein receptors. Nat Med 13(9): 1029-31 (2007).
-
(2007)
Nat Med
, vol.13
, Issue.9
, pp. 1029-1031
-
-
Sagare, A.1
Deane, R.2
Bell, R.D.3
Johnson, B.4
Hamm, K.5
Pendu, R.6
-
12
-
-
0034521392
-
Clearance of Alzheimer’s amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
-
Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, et al. Clearance of Alzheimer’s amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest 106(12): 1489-99 (2000).
-
(2000)
J Clin Invest
, vol.106
, Issue.12
, pp. 1489-1499
-
-
Shibata, M.1
Yamada, S.2
Kumar, S.R.3
Calero, M.4
Bading, J.5
Frangione, B.6
-
13
-
-
0036797713
-
Deposition of Alzheimer’s beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans
-
Vogelgesang S, Cascorbi I, Schroeder E, Pahnke J, Kroemer HK, Siegmund W, et al. Deposition of Alzheimer’s beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans. Pharmacogenetics 12(7): 535-41 (2002).
-
(2002)
Pharmacogenetics
, vol.12
, Issue.7
, pp. 535-541
-
-
Vogelgesang, S.1
Cascorbi, I.2
Schroeder, E.3
Pahnke, J.4
Kroemer, H.K.5
Siegmund, W.6
-
14
-
-
84904100818
-
Activity of P-Glycoprotein, a beta-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease
-
Deo AK, Borson S, Link JM, Domino K, Eary JF, Ke B, et al. Activity of P-Glycoprotein, a beta-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease. J Nucl Med 55(7):1106-11 (2014).
-
(2014)
J Nucl Med
, vol.55
, Issue.7
, pp. 1106-1111
-
-
Deo, A.K.1
Borson, S.2
Link, J.M.3
Domino, K.4
Eary, J.F.5
Ke, B.6
-
15
-
-
77951078680
-
Restoring blood-brain barrier Pglycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer’s disease
-
Hartz AM, Miller DS, Bauer B. Restoring blood-brain barrier Pglycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer’s disease. Mol Pharmacol 77(5): 715-23 (2010).
-
(2010)
Mol Pharmacol
, vol.77
, Issue.5
, pp. 715-723
-
-
Hartz, A.M.1
Miller, D.S.2
Bauer, B.3
-
16
-
-
0033616684
-
Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier
-
Rao VV, Dahlheimer JL, Bardgett ME, Snyder AZ, Finch RA, Sartorelli AC, et al. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. Proc Natl Acad Sci USA 96(7): 3900-5 (1999).
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.7
, pp. 3900-3905
-
-
Rao, V.V.1
Dahlheimer, J.L.2
Bardgett, M.E.3
Snyder, A.Z.4
Finch, R.A.5
Sartorelli, A.C.6
-
17
-
-
37249075973
-
Use of Z310 cells as an bloodcerebrospinal fluid barrier in vitro model: Tight junction proteins and transport properties
-
Shi LZ, Li GJ, Wang S, Zheng W. Use of Z310 cells as an bloodcerebrospinal fluid barrier in vitro model: tight junction proteins and transport properties. Toxicol In Vitro 22(1): 190-9 (2008).
-
(2008)
Toxicol in Vitro
, vol.22
, Issue.1
, pp. 190-199
-
-
Shi, L.Z.1
Li, G.J.2
Wang, S.3
Zheng, W.4
-
18
-
-
46949098349
-
Modulation of P-glycoprotein at the blood-brain barrier: Opportunities to improve central nervous system pharmacotherapy
-
Miller DS, Bauer B, Hartz AM. Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy. Pharmacol Rev 60(2):196-209 (2008).
-
(2008)
Pharmacol Rev
, vol.60
, Issue.2
, pp. 196-209
-
-
Miller, D.S.1
Bauer, B.2
Hartz, A.M.3
-
19
-
-
35148859731
-
MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier
-
Kuhnke D, Jedlitschky G, Grube M, Krohn M, Jucker M, Mosyagin I, et al. MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier. Brain Pathol 17(4): 347-53 (2007).
-
(2007)
Brain Pathol
, vol.17
, Issue.4
, pp. 347-353
-
-
Kuhnke, D.1
Jedlitschky, G.2
Grube, M.3
Krohn, M.4
Jucker, M.5
Mosyagin, I.6
-
20
-
-
0035112889
-
Sharom FJ, et al. Beta-Amyloid efflux mediated by p-glycoprotein
-
Lam FC, Liu R, Lu P, Shapiro AB, Renoir JM, Sharom FJ, et al. beta-Amyloid efflux mediated by p-glycoprotein. J Neurochem 6(4): 1121-8 (2001).
-
(2001)
J Neurochem
, vol.6
, Issue.4
, pp. 1121-1128
-
-
Lam, F.C.1
Liu, R.2
Lu, P.3
Shapiro, A.B.4
Renoir, J.M.5
-
21
-
-
27644489474
-
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model
-
Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, et al. P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model. J Clin Invest 115(11): 3285-90 (2005).
-
(2005)
J Clin Invest
, vol.115
, Issue.11
, pp. 3285-3290
-
-
Cirrito, J.R.1
Deane, R.2
Fagan, A.M.3
Spinner, M.L.4
Parsadanian, M.5
Finn, M.B.6
-
22
-
-
84863393540
-
Blood-brain barrier Pglycoprotein function in Alzheimer’s disease
-
van Assema DM, Lubberink M, Bauer M, van der Flier WM, Schuit RC, Windhorst AD, et al. Blood-brain barrier Pglycoprotein function in Alzheimer’s disease. Brain 135(Pt 1): 181-9 (2012).
-
(2012)
Brain
, vol.135
, pp. 181-189
-
-
Van Assema, D.M.1
Lubberink, M.2
Bauer, M.3
Van Der Flier, W.M.4
Schuit, R.C.5
Windhorst, A.D.6
-
24
-
-
33846558136
-
Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy
-
Yousif S, Marie-Claire C, Roux F, Scherrmann JM, Decleves X. Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy. Brain Res 134(1): 1-11 (2007).
-
(2007)
Brain Res
, vol.134
, Issue.1
, pp. 1-11
-
-
Yousif, S.1
Marie-Claire, C.2
Roux, F.3
Scherrmann, J.M.4
Decleves, X.5
-
25
-
-
3042543657
-
Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptormediated mechanism
-
Zhu HJ, Liu GQ. Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptormediated mechanism. Life Sci 75(11): 1313-22 (2004).
-
(2004)
Life Sci
, vol.75
, Issue.11
, pp. 1313-1322
-
-
Zhu, H.J.1
Liu, G.Q.2
-
26
-
-
3042789153
-
Deiodination of the iodinated amino acids
-
Stanbury JB. Deiodination of the iodinated amino acids. Ann N Y Acad Sci 86: 417-39 (1960).
-
(1960)
Ann N Y Acad Sci
, vol.86
, pp. 417-439
-
-
Stanbury, J.B.1
-
27
-
-
4644292545
-
Potential role of ABC transporters as a detoxification system at the blood-CSF barrier
-
de Lange EC. Potential role of ABC transporters as a detoxification system at the blood-CSF barrier. Adv Drug Deliv Rev 56(12): 1793-809 (2004).
-
(2004)
Adv Drug Deliv Rev
, vol.56
, Issue.12
, pp. 1793-1809
-
-
De Lange, E.C.1
-
28
-
-
79954520806
-
Peripheral reduction of beta-amyloid is sufficient to reduce brain beta-amyloid: Implications for Alzheimer’s disease
-
Sutcliffe JG, Hedlund PB, Thomas EA, Bloom FE, Hilbush BS. Peripheral reduction of beta-amyloid is sufficient to reduce brain beta-amyloid: implications for Alzheimer’s disease. J Neurosci Res 89(6): 808-14 (2011).
-
(2011)
J Neurosci Res
, vol.89
, Issue.6
, pp. 808-814
-
-
Sutcliffe, J.G.1
Hedlund, P.B.2
Thomas, E.A.3
Bloom, F.E.4
Hilbush, B.S.5
-
29
-
-
0035863055
-
Age-dependent changes in brain, CSF, and plasma amyloid (Beta) protein in the Tg2576 transgenic mouse model of Alzheimer’s disease
-
Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, Younkin SG. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer’s disease. J Neurosci 21(2): 372-81 (2001).
-
(2001)
J Neurosci
, vol.21
, Issue.2
, pp. 372-381
-
-
Kawarabayashi, T.1
Younkin, L.H.2
Saido, T.C.3
Shoji, M.4
Ashe, K.H.5
Younkin, S.G.6
-
30
-
-
84903761512
-
Abeta1-42 reduces Pglycoprotein in the blood-brain barrier through RAGE-NF-kappaB signaling
-
Park R, Kook SY, Park JC, Mook-Jung I. Abeta1-42 reduces Pglycoprotein in the blood-brain barrier through RAGE-NF-kappaB signaling. Cell Death Dis 5: e1299 (2014).
-
(2014)
Cell Death Dis
, vol.5
-
-
Park, R.1
Kook, S.Y.2
Park, J.C.3
Mook-Jung, I.4
-
31
-
-
47349110179
-
Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition
-
Zhou SF. Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition. Xenobiotica 38(7-8): 802-32 (2008).
-
(2008)
Xenobiotica
, vol.38
, Issue.7-8
, pp. 802-832
-
-
Zhou, S.F.1
-
32
-
-
84877107877
-
Modulation of multidrug resistance 1 expression and function in retinoblastoma cells by curcumin
-
Sreenivasan S, Ravichandran S, Vetrivel U, Krishnakumar S. Modulation of multidrug resistance 1 expression and function in retinoblastoma cells by curcumin. J Pharmacol Pharmacother 4(2):103-9 (2013).
-
(2013)
J Pharmacol Pharmacother
, vol.4
, Issue.2
, pp. 103-109
-
-
Sreenivasan, S.1
Ravichandran, S.2
Vetrivel, U.3
Krishnakumar, S.4
-
33
-
-
12844256659
-
A new method to measure intestinal activity of P-glycoprotein in avian and mammalian species
-
Green AK, Barnes DM, Karasov WH. A new method to measure intestinal activity of P-glycoprotein in avian and mammalian species. J Comp Physiol B 175(1): 57-66 (2005).
-
(2005)
J Comp Physiol B
, vol.175
, Issue.1
, pp. 57-66
-
-
Green, A.K.1
Barnes, D.M.2
Karasov, W.H.3
-
34
-
-
12744253433
-
Modulation of pglycoprotein transport function at the blood-brain barrier
-
Bauer B, Hartz AM, Fricker G, Miller DS. Modulation of pglycoprotein transport function at the blood-brain barrier. Exp Biol Med (Maywood) 230(2): 118-27 (2005).
-
(2005)
Exp Biol Med (Maywood)
, vol.230
, Issue.2
, pp. 118-127
-
-
Bauer, B.1
Hartz, A.M.2
Fricker, G.3
Miller, D.S.4
|