-
1
-
-
84875149194
-
Regulation of nucleosome dynamics by histone modifications
-
Zentner,G.E. and Henikoff,S. (2013) Regulation of nucleosome dynamics by histone modifications. Nat. Struct. Mol. Biol., 20, 259-266.
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 259-266
-
-
Zentner, G.E.1
Henikoff, S.2
-
2
-
-
66249105703
-
ATP-citrate lyase links cellular metabolism to histone acetylation
-
Wellen,K.E., Hatzivassiliou,G., Sachdeva,U.M., Bui,T.V., Cross,J.R. and Thompson,C.B. (2009) ATP-citrate lyase links cellular metabolism to histone acetylation. Science, 324, 1076-1080.
-
(2009)
Science
, vol.324
, pp. 1076-1080
-
-
Wellen, K.E.1
Hatzivassiliou, G.2
Sachdeva, U.M.3
Bui, T.V.4
Cross, J.R.5
Thompson, C.B.6
-
3
-
-
33745557847
-
Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription
-
Takahashi,H., McCaffery,J.M., Irizarry,R.A. and Boeke,J.D. (2006) Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription. Mol. Cell, 23, 207-217.
-
(2006)
Mol. Cell
, vol.23
, pp. 207-217
-
-
Takahashi, H.1
McCaffery, J.M.2
Irizarry, R.A.3
Boeke, J.D.4
-
4
-
-
84903954689
-
A nuclear pyruvate dehydrogenase complex is important for the generation of Acetyl-CoA and histone acetylation
-
Sutendra,G., Kinnaird,A., Dromparis,P., Paulin,R., Stenson,T.H., Haromy,A., Hashimoto,K., Zhang,N., Flaim,E. and Michelakis,E.D. (2014) A nuclear pyruvate dehydrogenase complex is important for the generation of Acetyl-CoA and histone acetylation. Cell, 158, 84-97.
-
(2014)
Cell
, vol.158
, pp. 84-97
-
-
Sutendra, G.1
Kinnaird, A.2
Dromparis, P.3
Paulin, R.4
Stenson, T.H.5
Haromy, A.6
Hashimoto, K.7
Zhang, N.8
Flaim, E.9
Michelakis, E.D.10
-
5
-
-
84862776933
-
Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase
-
Gao,X., Wang,H., Yang,J.J., Liu,X. and Liu,Z.R. (2012) Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase. Mol. Cell, 45, 598-609.
-
(2012)
Mol. Cell
, vol.45
, pp. 598-609
-
-
Gao, X.1
Wang, H.2
Yang, J.J.3
Liu, X.4
Liu, Z.R.5
-
6
-
-
40149095758
-
Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription
-
Lee,J., Kim,H.K., Han,Y.M. and Kim,J. (2008) Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription. Int. J. Biochem. Cell Biol., 40, 1043-1054.
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 1043-1054
-
-
Lee, J.1
Kim, H.K.2
Han, Y.M.3
Kim, J.4
-
7
-
-
79957567239
-
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
-
Luo,W., Hu,H., Chang,R., Zhong,J., Knabel,M., O'Meally,R., Cole,R.N., Pandey,A. and Semenza,G.L. (2011) Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell, 145, 732-744.
-
(2011)
Cell
, vol.145
, pp. 732-744
-
-
Luo, W.1
Hu, H.2
Chang, R.3
Zhong, J.4
Knabel, M.5
O'Meally, R.6
Cole, R.N.7
Pandey, A.8
Semenza, G.L.9
-
8
-
-
82555170271
-
Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation
-
Yang,W., Xia,Y., Ji,H., Zheng,Y., Liang,J., Huang,W., Gao,X., Aldape,K. and Lu,Z. (2011) Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation. Nature, 480, 118-122.
-
(2011)
Nature
, vol.480
, pp. 118-122
-
-
Yang, W.1
Xia, Y.2
Ji, H.3
Zheng, Y.4
Liang, J.5
Huang, W.6
Gao, X.7
Aldape, K.8
Lu, Z.9
-
9
-
-
84865266173
-
PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis
-
Yang,W., Xia,Y., Hawke,D., Li,X., Liang,J., Xing,D., Aldape,K., Hunter,T., Yung,W.K. and Lu,Z. (2012) PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis. Cell, 150, 685-696.
-
(2012)
Cell
, vol.150
, pp. 685-696
-
-
Yang, W.1
Xia, Y.2
Hawke, D.3
Li, X.4
Liang, J.5
Xing, D.6
Aldape, K.7
Hunter, T.8
Yung, W.K.9
Lu, Z.10
-
10
-
-
79954414352
-
Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription
-
Chueh,F.Y., Leong,K.F., Cronk,R.J., Venkitachalam,S., Pabich,S. and Yu,C.L. (2011) Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription. Cell Signal., 23, 1170-1178.
-
(2011)
Cell Signal.
, vol.23
, pp. 1170-1178
-
-
Chueh, F.Y.1
Leong, K.F.2
Cronk, R.J.3
Venkitachalam, S.4
Pabich, S.5
Yu, C.L.6
-
11
-
-
0033990325
-
Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis
-
Nebert,D.W., Roe,A.L., Dieter,M.Z., Solis,W.A., Yang,Y. and Dalton,T.P. (2000) Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis. Biochem. Pharmacol., 59, 65-85.
-
(2000)
Biochem. Pharmacol.
, vol.59
, pp. 65-85
-
-
Nebert, D.W.1
Roe, A.L.2
Dieter, M.Z.3
Solis, W.A.4
Yang, Y.5
Dalton, T.P.6
-
12
-
-
0842310349
-
CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species
-
Yusufzai,T.M., Tagami,H., Nakatani,Y. and Felsenfeld,G. (2004) CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species. Mol. Cell, 13, 291-298.
-
(2004)
Mol. Cell
, vol.13
, pp. 291-298
-
-
Yusufzai, T.M.1
Tagami, H.2
Nakatani, Y.3
Felsenfeld, G.4
-
13
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
Christofk,H.R., Vander Heiden,M.G., Harris,M.H., Ramanathan,A., Gerszten,R.E., Wei,R., Fleming,M.D., Schreiber,S.L. and Cantley,L.C. (2008) The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature, 452, 230-233.
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
14
-
-
0019827971
-
An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates
-
Hinman,L.M. and Blass,J.P. (1981) An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates. J. Biol. Chem., 256, 6583-6586.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 6583-6586
-
-
Hinman, L.M.1
Blass, J.P.2
-
15
-
-
84877781886
-
Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA
-
Nakamura,T., Pluskal,T., Nakaseko,Y. and Yanagida,M. (2012) Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA. Open Biol., 2, 120117.
-
(2012)
Open Biol.
, vol.2
-
-
Nakamura, T.1
Pluskal, T.2
Nakaseko, Y.3
Yanagida, M.4
-
16
-
-
0035943634
-
Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine
-
Adachi,J., Mori,Y., Matsui,S., Takigami,H., Fujino,J., Kitagawa,H., Miller,C.A. 3rd, Kato,T., Saeki,K. and Matsuda,T. (2001) Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine. J. Biol. Chem., 276, 31475-31478.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31475-31478
-
-
Adachi, J.1
Mori, Y.2
Matsui, S.3
Takigami, H.4
Fujino, J.5
Kitagawa, H.6
Miller, C.A.7
Kato, T.8
Saeki, K.9
Matsuda, T.10
-
17
-
-
23044500915
-
Pyruvate kinase type M2 and its role in tumor growth and spreading
-
Mazurek,S., Boschek,C.B., Hugo,F. and Eigenbrodt,E. (2005) Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin. Cancer Biol., 15, 300-308.
-
(2005)
Semin. Cancer Biol.
, vol.15
, pp. 300-308
-
-
Mazurek, S.1
Boschek, C.B.2
Hugo, F.3
Eigenbrodt, E.4
-
18
-
-
58249089741
-
Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3
-
Thangaraju,M., Carswell,K.N., Prasad,P.D. and Ganapathy,V. (2009) Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. Biochem. J., 417, 379-389.
-
(2009)
Biochem. J.
, vol.417
, pp. 379-389
-
-
Thangaraju, M.1
Carswell, K.N.2
Prasad, P.D.3
Ganapathy, V.4
-
19
-
-
0034652235
-
Effects of histone deacetylase inhibitors on the Ah receptor gene promoter
-
Garrison,P.M., Rogers,J.M., Brackney,W.R. and Denison,M.S. (2000) Effects of histone deacetylase inhibitors on the Ah receptor gene promoter. Arch. Biochem. Biophys., 374, 161-171.
-
(2000)
Arch. Biochem. Biophys.
, vol.374
, pp. 161-171
-
-
Garrison, P.M.1
Rogers, J.M.2
Brackney, W.R.3
Denison, M.S.4
-
20
-
-
0030667728
-
CBP/p300 functions as a possible transcriptional coactivator of Ah receptor nuclear translocator (Arnt)
-
Kobayashi,A., Numayama-Tsuruta,K., Sogawa,K. and Fujii-Kuriyama,Y. (1997) CBP/p300 functions as a possible transcriptional coactivator of Ah receptor nuclear translocator (Arnt). J. Biochem., 122, 703-710.
-
(1997)
J. Biochem.
, vol.122
, pp. 703-710
-
-
Kobayashi, A.1
Numayama-Tsuruta, K.2
Sogawa, K.3
Fujii-Kuriyama, Y.4
-
21
-
-
0036374212
-
Regulation of glycolysis by Raf protein serine/threonine kinases
-
Le Mellay,V., Houben,R., Troppmair,J., Hagemann,C., Mazurek,S., Frey,U., Beigel,J., Weber,C., Benz,R., Eigenbrodt,E. et al. (2002) Regulation of glycolysis by Raf protein serine/threonine kinases. Adv. Enzyme Regul., 42, 317-332.
-
(2002)
Adv. Enzyme Regul.
, vol.42
, pp. 317-332
-
-
Le Mellay, V.1
Houben, R.2
Troppmair, J.3
Hagemann, C.4
Mazurek, S.5
Frey, U.6
Beigel, J.7
Weber, C.8
Benz, R.9
Eigenbrodt, E.10
-
22
-
-
0022930036
-
The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing
-
Noguchi,T., Inoue,H. and Tanaka,T. (1986) The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing. J. Biol. Chem., 261, 13807-13812.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 13807-13812
-
-
Noguchi, T.1
Inoue, H.2
Tanaka, T.3
-
23
-
-
79954526957
-
Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: Identification of mitochondrial histones
-
Choi,Y.S., Hoon Jeong,J., Min,H.K., Jung,H.J., Hwang,D., Lee,S.W. and Kim Pak,Y. (2011) Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: identification of mitochondrial histones. Mol. Biosyst., 7, 1523-1536.
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 1523-1536
-
-
Choi, Y.S.1
Hoon Jeong, J.2
Min, H.K.3
Jung, H.J.4
Hwang, D.5
Lee, S.W.6
Kim Pak, Y.7
-
24
-
-
77957375417
-
Evidence that core histone H3 is targeted to the mitochondria in Brassica oleracea
-
Zanin,M.K., Donohue,J.M. and Everitt,B.A. (2010) Evidence that core histone H3 is targeted to the mitochondria in Brassica oleracea. Cell Biol. Int., 34, 997-1003.
-
(2010)
Cell Biol. Int.
, vol.34
, pp. 997-1003
-
-
Zanin, M.K.1
Donohue, J.M.2
Everitt, B.A.3
-
25
-
-
0026046412
-
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: Comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Bjeldanes,L.F., Kim,J.Y., Grose,K.R., Bartholomew,J.C. and Bradfield,C.A. (1991) Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc. Natl. Acad. Sci. U.S.A., 88, 9543-9547.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 9543-9547
-
-
Bjeldanes, L.F.1
Kim, J.Y.2
Grose, K.R.3
Bartholomew, J.C.4
Bradfield, C.A.5
-
26
-
-
0029418619
-
Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands
-
Rannug,U., Rannug,A., Sjoberg,U., Li,H., Westerholm,R. and Bergman,J. (1995) Structure elucidation of two tryptophan-derived, high affinity Ah receptor ligands. Chem. Biol., 2, 841-845.
-
(1995)
Chem. Biol.
, vol.2
, pp. 841-845
-
-
Rannug, U.1
Rannug, A.2
Sjoberg, U.3
Li, H.4
Westerholm, R.5
Bergman, J.6
-
27
-
-
0033128165
-
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
-
Hoessel,R., Leclerc,S., Endicott,J.A., Nobel,M.E., Lawrie,A., Tunnah,P., Leost,M., Damiens,E., Marie,D., Marko,D. et al. (1999) Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases. Nat. Cell Biol., 1, 60-67.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 60-67
-
-
Hoessel, R.1
Leclerc, S.2
Endicott, J.A.3
Nobel, M.E.4
Lawrie, A.5
Tunnah, P.6
Leost, M.7
Damiens, E.8
Marie, D.9
Marko, D.10
-
28
-
-
3242795083
-
Comparison of gene expression patterns between 2,3,7,8-tetrachlorodibenzo-p-dioxin and a natural arylhydrocarbon receptor ligand, indirubin
-
Adachi,J., Mori,Y., Matsui,S. and Matsuda,T. (2004) Comparison of gene expression patterns between 2,3,7,8-tetrachlorodibenzo-p-dioxin and a natural arylhydrocarbon receptor ligand, indirubin. Toxicol. Sci., 80, 161-169.
-
(2004)
Toxicol. Sci.
, vol.80
, pp. 161-169
-
-
Adachi, J.1
Mori, Y.2
Matsui, S.3
Matsuda, T.4
-
29
-
-
0031819240
-
Pyruvate kinase isoenzyme shift from L-type to M2-type is a late event in hepatocarcinogenesis induced in rats by a choline-deficient/DL-ethionine-supplemented diet
-
Hacker,H.J., Steinberg,P. and Bannasch,P. (1998) Pyruvate kinase isoenzyme shift from L-type to M2-type is a late event in hepatocarcinogenesis induced in rats by a choline-deficient/DL-ethionine-supplemented diet. Carcinogenesis, 19, 99-107.
-
(1998)
Carcinogenesis
, vol.19
, pp. 99-107
-
-
Hacker, H.J.1
Steinberg, P.2
Bannasch, P.3
-
30
-
-
0028881819
-
Temporally distinctive changes of alternative splicing patterns during myogenic differentiation of C2C12 cells
-
Harada,Y., Nakamura,M. and Asano,A. (1995) Temporally distinctive changes of alternative splicing patterns during myogenic differentiation of C2C12 cells. J. Biochem., 118, 780-790.
-
(1995)
J. Biochem.
, vol.118
, pp. 780-790
-
-
Harada, Y.1
Nakamura, M.2
Asano, A.3
-
31
-
-
0029068251
-
Molecular cloning of the complementary DNA for the mouse pyruvate kinase M-2 gene whose expression is dependent upon cell differentiation
-
Izumi,S., Manabe,A., Tomoyasu,A., Kihara-Negishi,F. and Ariga,H. (1995) Molecular cloning of the complementary DNA for the mouse pyruvate kinase M-2 gene whose expression is dependent upon cell differentiation. Biochim. Biophys. Acta, 1267, 135-138.
-
(1995)
Biochim. Biophys. Acta
, vol.1267
, pp. 135-138
-
-
Izumi, S.1
Manabe, A.2
Tomoyasu, A.3
Kihara-Negishi, F.4
Ariga, H.5
-
32
-
-
0023816079
-
Pyruvate kinase isoenzyme transitions in cultures of fetal rat hepatocytes
-
Scott,R.J., English,V., Noguchi,T., Tanaka,T. and Yeoh,G.C. (1988) Pyruvate kinase isoenzyme transitions in cultures of fetal rat hepatocytes. Cell Differ. Dev., 25, 109-118.
-
(1988)
Cell Differ. Dev.
, vol.25
, pp. 109-118
-
-
Scott, R.J.1
English, V.2
Noguchi, T.3
Tanaka, T.4
Yeoh, G.C.5
-
33
-
-
0020010617
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
-
Poland,A. and Knutson,J.C. (1982) 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol., 22, 517-554.
-
(1982)
Annu. Rev. Pharmacol. Toxicol.
, vol.22
, pp. 517-554
-
-
Poland, A.1
Knutson, J.C.2
-
34
-
-
0024997614
-
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
-
Safe,S. (1990) Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit. Rev. Toxicol., 21, 51-88.
-
(1990)
Crit. Rev. Toxicol.
, vol.21
, pp. 51-88
-
-
Safe, S.1
-
35
-
-
0025606624
-
A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: Recent advances toward understanding the mechanism
-
Couture,L.A., Abbott,B.D. and Birnbaum,L.S. (1990) A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism. Teratology, 42, 619-627.
-
(1990)
Teratology
, vol.42
, pp. 619-627
-
-
Couture, L.A.1
Abbott, B.D.2
Birnbaum, L.S.3
-
36
-
-
0031241140
-
Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor
-
Mimura,J., Yamashita,K., Nakamura,K., Morita,M., Takagi,T.N., Nakao,K., Ema,M., Sogawa,K., Yasuda,M., Katsuki,M. et al. (1997) Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Genes Cells, 2, 645-654.
-
(1997)
Genes Cells
, vol.2
, pp. 645-654
-
-
Mimura, J.1
Yamashita, K.2
Nakamura, K.3
Morita, M.4
Takagi, T.N.5
Nakao, K.6
Ema, M.7
Sogawa, K.8
Yasuda, M.9
Katsuki, M.10
-
37
-
-
0032938107
-
Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice
-
Peters,J.M., Narotsky,M.G., Elizondo,G., Fernandez-Salguero,P.M., Gonzalez,F.J. and Abbott,B.D. (1999) Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice. Toxicol. Sci., 47, 86-92.
-
(1999)
Toxicol. Sci.
, vol.47
, pp. 86-92
-
-
Peters, J.M.1
Narotsky, M.G.2
Elizondo, G.3
Fernandez-Salguero, P.M.4
Gonzalez, F.J.5
Abbott, B.D.6
-
38
-
-
84867619803
-
Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells
-
Jin,U.H., Lee,S.O. and Safe,S. (2012) Aryl hydrocarbon receptor (AHR)-active pharmaceuticals are selective AHR modulators in MDA-MB-468 and BT474 breast cancer cells. J. Pharmacol. Exp. Ther., 343, 333-341.
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.343
, pp. 333-341
-
-
Jin, U.H.1
Lee, S.O.2
Safe, S.3
|