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Volumn 21, Issue 4, 2016, Pages

3,5,6,7,8,31,41 -Heptamethoxyflavone, a citrus flavonoid, Ameliorates corticosterone-induced depression-like behavior and restores brain-derived neurotrophic factor expression, neurogenesis, and neuroplasticity in the hippocampus

Author keywords

Brain derived; Corticosterone; Depression; Heptamethoxyflavone; Hippocampus; Neurogenesis; Neurotrophic factor

Indexed keywords

3,3',4',5,6,7,8-HEPTAMETHOXYFLAVONE; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; FLAVONOID;

EID: 84966262774     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules21040541     Document Type: Article
Times cited : (56)

References (41)
  • 1
    • 2442673159 scopus 로고    scopus 로고
    • Life stress, genes, and depression: Multiple pathways lead to increased risk and new opportunities for intervention
    • [CrossRef] [PubMed]
    • Charney, D.S.; Manji, H.K. Life stress, genes, and depression: Multiple pathways lead to increased risk and new opportunities for intervention. Sci. STKE 2004, 225, re5. [CrossRef] [PubMed]
    • (2004) Sci. STKE , vol.225 , pp. re5
    • Charney, D.S.1    Manji, H.K.2
  • 2
    • 50549092885 scopus 로고    scopus 로고
    • The HPA axis in major depression: Classical theories and new developments
    • [CrossRef] [PubMed]
    • Pariante, C.M.; Lightman, S.L. The HPA axis in major depression: Classical theories and new developments. Trends Neurosci. 2008, 31, 464-468. [CrossRef] [PubMed]
    • (2008) Trends Neurosci , vol.31 , pp. 464-468
    • Pariante, C.M.1    Lightman, S.L.2
  • 3
    • 0028299375 scopus 로고
    • Glucocorticoids and the genesis of depressive illness. A psychobiological model
    • [CrossRef] [PubMed]
    • Dinan, T.G. Glucocorticoids and the genesis of depressive illness. A psychobiological model. Br. J. Psychiatry 1994, 164, 365-371. [CrossRef] [PubMed]
    • (1994) Br. J. Psychiatry , vol.164 , pp. 365-371
    • Dinan, T.G.1
  • 4
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • [CrossRef] [PubMed]
    • Duman, R.; Monteggia, I. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 2006, 59, 1116-1127. [CrossRef] [PubMed]
    • (2006) Biol. Psychiatry , Issue.59 , pp. 1116-1127
    • Duman, R.1    Monteggia, I.2
  • 5
    • 80052682919 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) infusion restored astrocytic plasticity in the hippocampus of a rat model of depression
    • [CrossRef] [PubMed]
    • Ye, Y.; Wang, G.; Wang, H.; Wang, X. Brain-derived neurotrophic factor (BDNF) infusion restored astrocytic plasticity in the hippocampus of a rat model of depression. Neurosci. Lett. 2011, 503, 15-19. [CrossRef] [PubMed]
    • (2011) Neurosci. Lett. , Issue.503 , pp. 15-19
    • Ye, Y.1    Wang, G.2    Wang, H.3    Wang, X.4
  • 6
    • 34548790683 scopus 로고    scopus 로고
    • Hippocampal neurogenesis, depressive disorders, and antidepressant therapy
    • [CrossRef] [PubMed]
    • Paizanis, E.; Hamon, M.; Lanfumey, L. Hippocampal neurogenesis, depressive disorders, and antidepressant therapy. Neural Plast. 2007, 2007. [CrossRef] [PubMed]
    • (2007) Neural Plast. , pp. 2007
    • Paizanis, E.1    Hamon, M.2    Lanfumey, L.3
  • 7
    • 34548336779 scopus 로고    scopus 로고
    • New insights into BDNF function in depression and anxiety
    • [CrossRef] [PubMed]
    • Martinowich, K.; Manji, H.; Lu, B. New insights into BDNF function in depression and anxiety. Nat. Neurosci. 2007, 10, 1089-1093. [CrossRef] [PubMed]
    • (2007) Nat. Neurosci. , vol.10 , pp. 1089-1093
    • Martinowich, K.1    Manji, H.2    Lu, B.3
  • 8
    • 84898767578 scopus 로고    scopus 로고
    • 3,5,6,7,8,31,41 -Heptamethoxyflavone, a citrus flavonoid, on protection against memory impairment and neuronal cell death in a global cerebral ischemia mouse model
    • [CrossRef] [PubMed]
    • Okuyama,S. Morita M. Miyoshi, K. Nishigawa, Y. Kaji M. Sawamoto A. Terugo T. Toyoda N. Makihata N. Amakura Y.et al.3,5,6,7,8,31 ,41 -Heptamethoxyflavone, a citrus flavonoid, on protection against memory impairment and neuronal cell death in a global cerebral ischemia mouse modelNeurochem. Int.20147030-38[CrossRef] [PubMed]
    • (2014) Neurochem. Int. , vol.70 , pp. 30-38
    • Okuyama, S.1    Morita, M.2    Miyoshi, K.3    Nishigawa, Y.4    Kaji, M.5    Sawamoto, A.6    Terugo, T.7    Toyoda, N.8    Makihata, N.9    Amakura, Y.10
  • 9
    • 84867733887 scopus 로고    scopus 로고
    • Heptamethoxyflavone, a citrus flavonoid, enhances brain-derived neurotrophic factor production and neurogenesis in the hippocampus following cerebral global ischemia in mice
    • [CrossRef] [PubMed]
    • Okuyama, S.; Shimada, N.; Kaji, M.; Morita, M.; Miyoshi, K.; Minami, S.; Amakura, Y.; Yoshimura, M.; Yoshida, T.; Watanabe, S.; et al. Heptamethoxyflavone, a citrus flavonoid, enhances brain-derived neurotrophic factor production and neurogenesis in the hippocampus following cerebral global ischemia in mice. Neurosci. Lett. 2012, 528, 190-195. [CrossRef] [PubMed]
    • (2012) Neurosci. Lett. , vol.528 , pp. 190-195
    • Okuyama, S.1    Shimada, N.2    Kaji, M.3    Morita, M.4    Miyoshi, K.5    Minami, S.6    Amakura, Y.7    Yoshimura, M.8    Yoshida, T.9    Watanabe, S.10
  • 10
    • 0037840278 scopus 로고    scopus 로고
    • Depression-like change of the sleep-EEG during high dose corticosteroid treatment in patients with multiple sclerosis
    • [CrossRef]
    • Antonijevic, I.A.; Steiger, A. Depression-like change of the sleep-EEG during high dose corticosteroid treatment in patients with multiple sclerosis. Psychoneuroendocrinology 2003, 28, 780-795. [CrossRef]
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 780-795
    • Antonijevic, I.A.1    Steiger, A.2
  • 11
    • 84966264405 scopus 로고    scopus 로고
    • A novel 2-decenoic acid thioester ameliorates corticosterone-induced depression- and anxiety-like behaviors and normalizes reduced hippocampal signal transduction in treated mice
    • [CrossRef] [PubMed]
    • Shibata, S.; Iinuma, M.; Soumiya, H.; Fukumitsu, H.; Furukawa, Y.; Furukawa, S. A novel 2-decenoic acid thioester ameliorates corticosterone-induced depression- and anxiety-like behaviors and normalizes reduced hippocampal signal transduction in treated mice. Pharmacol. Res. Perspect. 2015, 3, e00132. [CrossRef] [PubMed]
    • (2015) Pharmacol. Res. Perspect , vol.3 , pp. e00132
    • Shibata, S.1    Iinuma, M.2    Soumiya, H.3    Fukumitsu, H.4    Furukawa, Y.5    Furukawa, S.6
  • 12
    • 33748437647 scopus 로고    scopus 로고
    • Chronic corticosterone decreases brain-derived neurotrophic factor (BDNF) mRNA and protein in the hippocampus, but not in the frontal cortex, of the rat
    • [CrossRef] [PubMed]
    • Jacobsen, J.P.; Mørk, A. Chronic corticosterone decreases brain-derived neurotrophic factor (BDNF) mRNA and protein in the hippocampus, but not in the frontal cortex, of the rat. Brain Res. 2006, 1110, 221-225. [CrossRef] [PubMed]
    • (2006) Brain Res , vol.1110 , pp. 221-225
    • Jacobsen, J.P.1    Mørk, A.2
  • 13
    • 33646150655 scopus 로고    scopus 로고
    • Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: Differential regulation of specific exons by antidepressants and corticosterone
    • [CrossRef] [PubMed]
    • Dwivedi, Y.; Rizavi, H.S.; Pandey, G.N. Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: Differential regulation of specific exons by antidepressants and corticosterone. Neuroscience 2006, 139, 1017-1029. [CrossRef] [PubMed]
    • (2006) Neuroscience , vol.139 , pp. 1017-1029
    • Dwivedi, Y.1    Rizavi, H.S.2    Pandey, G.N.3
  • 15
    • 84954338705 scopus 로고    scopus 로고
    • Berberine up-regulates the BDNF expression in hippocampus and attenuates corticosterone-induced depressive-like behavior in mice
    • [CrossRef] [PubMed]
    • Shen, J.D.; Ma, L.G.; Hu, C.Y.; Pei, Y.Y.; Jin, S.L.; Fang, X.Y.; Li, Y.C. Berberine up-regulates the BDNF expression in hippocampus and attenuates corticosterone-induced depressive-like behavior in mice. Neurosci. Lett. 2016, 614, 77-82. [CrossRef] [PubMed]
    • (2016) Neurosci. Lett. , vol.614 , pp. 77-82
    • Shen, J.D.1    Ma, L.G.2    Hu, C.Y.3    Pei, Y.Y.4    Jin, S.L.5    Fang, X.Y.6    Li, Y.C.7
  • 16
    • 38549098646 scopus 로고    scopus 로고
    • A mouse model of depression induced by repeated corticosterone injections
    • [CrossRef] [PubMed]
    • Zhao, Y.; Ma, R.; Shen, J.; Su, H.; Xing, D.; Du, L. A mouse model of depression induced by repeated corticosterone injections. Eur. J. Pharmacol. 2008, 581, 113-120. [CrossRef] [PubMed]
    • (2008) Eur. J. Pharmacol. , Issue.581 , pp. 113-120
    • Zhao, Y.1    Ma, R.2    Shen, J.3    Su, H.4    Xing, D.5    Du, L.6
  • 17
    • 19944418868 scopus 로고    scopus 로고
    • Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test
    • [CrossRef] [PubMed]
    • Cryan, J.F.; Valentino, R.J.; Lucki, I. Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci. Biobehav. Rev. 2005, 29, 547-569. [CrossRef] [PubMed]
    • (2005) Neurosci. Biobehav. Rev. , Issue.29 , pp. 547-569
    • Cryan, J.F.1    Valentino, R.J.2    Lucki, I.3
  • 18
    • 84873604016 scopus 로고    scopus 로고
    • The brain derived neurotrophic factor and influences of stress in depression
    • Kimpton, J. The brain derived neurotrophic factor and influences of stress in depression. Psychiatr. Danub. 2012, 24, 169-171.
    • (2012) Psychiatr. Danub. , vol.24 , pp. 169-171
    • Kimpton, J.1
  • 19
    • 33745728406 scopus 로고    scopus 로고
    • Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis
    • [CrossRef] [PubMed]
    • Mayer, J.L.; Klumpers, L.; Maslam, S.; de Kloet, E.R.; Joëls, M.; Lucassen, P.J. Brief treatment with the glucocorticoid receptor antagonist mifepristone normalises the corticosterone-induced reduction of adult hippocampal neurogenesis. J. Neuroendocrinol. 2006, 18, 629-631. [CrossRef] [PubMed]
    • (2006) J. Neuroendocrinol. , vol.18 , pp. 629-631
    • Mayer, J.L.1    Klumpers, L.2    Maslam, S.3    De Kloet, E.R.4    Joëls, M.5    Lucassen, P.J.6
  • 20
    • 36949036445 scopus 로고    scopus 로고
    • Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress
    • [CrossRef] [PubMed]
    • Oomen, C.A.; Mayer, J.L.; de Kloet, E.R.; Joëls, M.; Lucassen, P.J. Brief treatment with the glucocorticoid receptor antagonist mifepristone normalizes the reduction in neurogenesis after chronic stress. Eur. J. Neurosci. 2007, 26, 3395-3401. [CrossRef] [PubMed]
    • (2007) Eur. J. Neurosci. , vol.26 , pp. 3395-3401
    • Oomen, C.A.1    Mayer, J.L.2    De Kloet, E.R.3    Joëls, M.4    Lucassen, P.J.5
  • 21
    • 55349126039 scopus 로고    scopus 로고
    • Detailed state model of CaMKII activation and Autophosphorylation
    • [CrossRef] [PubMed]
    • Luěí V.; Greif, G.J.; Kennedy, M.B. Detailed State Model of CaMKII Activation and Autophosphorylation. Eur. Biophys. J. 2008, 38, 83-98. [CrossRef] [PubMed]
    • (2008) Eur. Biophys J. , vol.38 , pp. 83-98
    • Luěí, V.1    Greif, G.J.2    Kennedy, M.B.3
  • 22
    • 57649178315 scopus 로고    scopus 로고
    • Corticosterone regulates pERK1/2 map kinase in a choronic depression model
    • [CrossRef] [PubMed]
    • Gourley, S.L.; Wu, F.J.; Taylor, J.R. Corticosterone regulates pERK1/2 map kinase in a choronic depression model. Ann. N. Y. Acad. Sci. 2008, 1148, 509-514. [CrossRef] [PubMed]
    • (2008) Ann. N. Y. Acad. Sci. , vol.1148 , pp. 509-514
    • Gourley, S.L.1    Wu, F.J.2    Taylor, J.R.3
  • 23
    • 38349158085 scopus 로고    scopus 로고
    • Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression
    • [CrossRef] [PubMed]
    • Gourley, S.L.; Wu, F.J.; Kiraly, D.D.; Ploski, J.E.; Kedves, A.T.; Duman, R.S.; Taylor, J.R. Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression. Biol. Psychiatry 2008, 63, 353-359. [CrossRef] [PubMed]
    • (2008) Biol. Psychiatry , vol.63 , pp. 353-359
    • Gourley, S.L.1    Wu, F.J.2    Kiraly, D.D.3    Ploski, J.E.4    Kedves, A.T.5    Duman, R.S.6    Taylor, J.R.7
  • 25
    • 2042546746 scopus 로고    scopus 로고
    • In search of a depressed mouse: Utility of models for studying depression-related behavior in genetically modified mice
    • [CrossRef] [PubMed]
    • Cryan, J.F.; Mombereau, C. In search of a depressed mouse: Utility of models for studying depression-related behavior in genetically modified mice. Mol. Psychiatry 2004, 9, 326-357. [CrossRef] [PubMed]
    • (2004) Mol. Psychiatry , vol.9 , pp. 326-357
    • Cryan, J.F.1    Mombereau, C.2
  • 26
    • 14844298782 scopus 로고    scopus 로고
    • Is mood chemistry?
    • [CrossRef] [PubMed]
    • Castrén, E. Is mood chemistry? Nat. Rev. Neurosci. 2005, 6, 241-246. [CrossRef] [PubMed]
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 241-246
    • Castrén, E.1
  • 28
    • 84922681032 scopus 로고    scopus 로고
    • Integrating the monoamine, neurotrophin and cytokine hypotheses of depression-A central role for the serotonin transporter?
    • [CrossRef] [PubMed]
    • Haase, J.; Brown, E. Integrating the monoamine, neurotrophin and cytokine hypotheses of depression-a central role for the serotonin transporter? Pharmacol. Ther. 2015, 147. [CrossRef] [PubMed]
    • (2015) Pharmacol. Ther. , vol.147
    • Haase, J.1    Brown, E.2
  • 29
    • 84956603272 scopus 로고    scopus 로고
    • Inflammatory mechanisms contribute to microembolism-induced anxiety-like and depressive-like behaviors
    • [CrossRef] [PubMed]
    • Nemeth, C.L.; Miller, A.H.; Tansey, M.G.; Neigh, G.N. Inflammatory mechanisms contribute to microembolism-induced anxiety-like and depressive-like behaviors. Behav. Brain Res. 2016, 303, 160-167. [CrossRef] [PubMed]
    • (2016) Behav. Brain Res. , vol.303 , pp. 160-167
    • Nemeth, C.L.1    Miller, A.H.2    Tansey, M.G.3    Neigh, G.N.4
  • 30
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: A convergence of mechanisms
    • [CrossRef] [PubMed]
    • Pittenger, C.; Duman, R.S. Stress, depression, and neuroplasticity: A convergence of mechanisms. Neuropsychopharmacology 2008, 33, 88-109. [CrossRef] [PubMed]
    • (2008) Neuropsychopharmacology , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 31
    • 13944257674 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    • [CrossRef] [PubMed]
    • Sairanen, M.; Lucas, G.; Ernfors, P.; Castrén, M.; Castrén, E. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J. Neurosci. 2005, 25, 1089-1094. [CrossRef] [PubMed]
    • (2005) J. Neurosci , vol.25 , pp. 1089-1094
    • Sairanen, M.1    Lucas, G.2    Ernfors, P.3    Castrén, M.4    Castrén, E.5
  • 32
    • 84866281766 scopus 로고    scopus 로고
    • Effects of fluoxetine on plasticity and apoptosis evoked by chronic stress in rat prefrontal cortex
    • [CrossRef] [PubMed]
    • Djordjevic, A.; Djordjevic, J.; Elakoviæ, I.; Adzic, M.; Matiæ, G.; Radojcic, M.B. Effects of fluoxetine on plasticity and apoptosis evoked by chronic stress in rat prefrontal cortex. Eur. J. Pharmacol. 2012, 693, 37-44. [CrossRef] [PubMed]
    • (2012) Eur. J. Pharmacol. , vol.693 , pp. 37-44
    • Djordjevic, A.1    Djordjevic, J.2    Elakoviæ, I.3    Adzic, M.4    Matiæ, G.5    Radojcic, M.B.6
  • 34
    • 84875235624 scopus 로고    scopus 로고
    • Antidepressants act directly on astrocytes: Evidences and functional consequences
    • Czéh, B; di Benedetto, B. Antidepressants act directly on astrocytes: Evidences and functional consequences. Eur. Neuropsychopharmacol. 2013, 23, 171-185.
    • (2013) Eur. Neuropsychopharmacol. , vol.23 , pp. 171-185
    • Czéh, B.1    Di Benedetto, B.2
  • 36
    • 0041880262 scopus 로고    scopus 로고
    • Untreated depression and hippocampal volume loss
    • [CrossRef] [PubMed]
    • Sheline, Y.I.; Gado, M.H.; Kraemer, H.C. Untreated depression and hippocampal volume loss. Am. J. Psychiatry 2003, 160, 1516-1518. [CrossRef] [PubMed]
    • (2003) Am. J. Psychiatry , vol.160 , pp. 1516-1518
    • Sheline, Y.I.1    Gado, M.H.2    Kraemer, H.C.3
  • 37
    • 84924739769 scopus 로고    scopus 로고
    • Chronic corticosterone exposure reduces hippocampal astrocyte structural plasticity and induces hippocampal atrophy in mice
    • [CrossRef] [PubMed]
    • Zhang, H.; Zhao, Y.; Wang, Z. Chronic corticosterone exposure reduces hippocampal astrocyte structural plasticity and induces hippocampal atrophy in mice. Neurosci. Lett. 2015, 592, 76-81. [CrossRef] [PubMed]
    • (2015) Neurosci. Lett. , vol.592 , pp. 76-81
    • Zhang, H.1    Zhao, Y.2    Wang, Z.3
  • 39
    • 0017651126 scopus 로고    scopus 로고
    • Behavioral despair in mice: A primary screening test for antidepressants
    • Porsolt, R.D.; Bertin, A.; Jalfre, M. Behavioral despair in mice: A primary screening test for antidepressants. Arch. Int. Pharmacodyn. 1997, 229, 327-336.
    • (1997) Arch. Int. Pharmacodyn. , vol.229 , pp. 327-336
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3
  • 40
    • 0021990491 scopus 로고
    • The tail suspension test: A new method for screening antidepressants in mice
    • [CrossRef] [PubMed]
    • Steru, L.; Chermat, R.; Thierry, B.; Simon, P. The tail suspension test: A new method for screening antidepressants in mice. Psychopharmacology 1985, 85, 367-370. [CrossRef] [PubMed]
    • (1985) Psychopharmacology , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 41
    • 58149379158 scopus 로고    scopus 로고
    • Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1
    • [CrossRef] [PubMed]
    • Sato, S.; Xu, J.; Okuyama, S.; Martinez, L.B.; Walsh, S.M.; Jacobsen, M.T.; Swan, R.J.; Schlautman, J.D.; Ciborowski, P.; Ikezu, T. Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1. J. Neurosci. 2008, 28, 14511-14521. [CrossRef] [PubMed]
    • (2008) J. Neurosci. , vol.28 , pp. 14511-14521
    • Sato, S.1    Xu, J.2    Okuyama, S.3    Martinez, L.B.4    Walsh, S.M.5    Jacobsen, M.T.6    Swan, R.J.7    Schlautman, J.D.8    Ciborowski, P.9    Ikezu, T.10


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