SHCBP1 is over-expressed in breast cancer and is important in the proliferation and apoptosis of the human malignant breast cancer cell line

Gene

Volumn 587, Issue 1, 2016, Pages 91-97

  Feng, Wen ^a   Li, Hong Chang ^a   Xu, Ke ^a   Chen, Ya Feng ^a   Pan, Li Yun ^a   Mei, Yi ^a   Cai, Han ^a   Jiang, Yi Ming ^a   Chen, Teng ^a   Feng, Dian Xu ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Breast cancer; CRISPR CAS9; Proliferation; SHCBP1

Indexed keywords

BINDING PROTEIN; BIOLOGICAL MARKER; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; MESSENGER RNA; PROTEIN BCL 2; PROTEIN SH2; PROTEIN SHC; SHC SH2 BINDING PROTEIN 1; UNCLASSIFIED DRUG; SHC SIGNALING ADAPTOR PROTEIN; SHCBP1 PROTEIN, HUMAN;

ADULT; APOPTOSIS; ARTICLE; BRDU ASSAY; BREAST CANCER; CANCER DIAGNOSIS; CANCER PROGNOSIS; CANCER SURVIVAL; CELL CYCLE ASSAY; CELL CYCLE M PHASE; CELL PROLIFERATION; CLINICAL EVALUATION; COLONY FORMING UNIT; CONTROLLED STUDY; CRISPR CAS SYSTEM; FEMALE; GENE INACTIVATION; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MCF 7 CELL LINE; MOLECULAR DIAGNOSIS; MTT ASSAY; PRIORITY JOURNAL; UPREGULATION; WESTERN BLOTTING; BREAST NEOPLASMS; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PROGNOSIS; TUMOR CELL LINE;

ADULT; APOPTOSIS; BIOMARKERS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE KNOCKOUT TECHNIQUES; HUMANS; MIDDLE AGED; PROGNOSIS; SHC SIGNALING ADAPTOR PROTEINS;

EID: 84965145000     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2016.04.046     Document Type: Article

References (21)

1. Asano E., et al. SHCBP1 is required for midbody organization and cytokinesis completion. Cell Cycle (Georgetown, Tex.) 2014, 13(17):2744-2751.
2. Buckley M.W., et al. Unexpected phenotype of mice lacking Shcbp1, a protein induced during T cell proliferation. PLoS One 2014, 9:e105576. 10.1371/journal.pone.0105576.
3. Chen Y., et al. EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation. Mol. Biol. Cell 2008, 19(7):2973-2983.
4. Cho S.W., et al. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat. Biotechnol. 2013, 31(3):230-232.
5. Cong L., et al. Multiplex genome engineering using CRISPR/Cas systems. Science (New York, N.Y.) 2013, 339(6121):819-823.
6. Eckerle S., et al. Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma. Leukemia 2009, 23(11):2129-2138.
7. Guo L., et al. Chemokine axes CXCL12/CXCR4 and CXCL16/CXCR6 correlate with lymph node metastasis in epithelial ovarian carcinoma. Chin. J. Cancer 2011, 30(5):336-343.
8. Jinek M., et al. RNA-programmed genome editing in human cells. eLife 2013, 2:e00471.
9. Koul H.K., Pal M., Koul S. Role of p38 MAP kinase signal transduction in solid tumors. Genes Cancer 2013, 4(9-10):342-359.
10. Kupershmidt I., et al. Ontology-based meta-analysis of global collections of high-throughput public data. PLoS One 2010, 5(9):e13066.
11. Lu Z. Nonmetabolic functions of pyruvate kinase isoform M2 in controlling cell cycle progression and tumorigenesis. Chin. J. Cancer 2012, 31(1):5-7.
12. Mali P., et al. RNA-guided human genome engineering via Cas9. Science (New York, N.Y.) 2013, 339(6121):823-826.
13. Ornitz D.M., Itoh N. The fibroblast growth factor signaling pathway. Wiley Interdiscip. Rev. Dev. Biol. 2015, 4(3):215-266.
14. Piccaluga P.P., et al. Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets. J. Clin. Investig. 2007, 117(3):823-834.
15. Qu W.-s., et al. Inhibition of EGFR/MAPK signaling reduces microglial inflammatory response and the associated secondary damage in rats after spinal cord injury. J. Neuroinflammation 2012, 9:178-178.
16. Sanchez-Rivera F.J., Jacks T. Applications of the CRISPR-Cas9 system in cancer biology. Nat. Rev. Cancer 2015, 15(7):387-395.
17. Tao H.-C., et al. Targeting SHCBP1 inhibits cell proliferation in human hepatocellular carcinoma cells. Asian Pac. J. Cancer Prev.: APJCP 2013, 14(10):5645-5650.
18. Torre L.A., et al. Global cancer statistics, 2012. CA Cancer J. Clin. 2015, 65(2):87-108.
19. Truffinet V., et al. The 3' IgH locus control region is sufficient to deregulate a c-myc transgene and promote mature B cell malignancies with a predominant Burkitt-like phenotype. J. Immunol. 2007, 179(9):6033-6042.
20. Wan L., Pantel K., Kang Y. Tumor metastasis: moving new biological insights into the clinic. Nat. Med. 2013, 19(11):1450-1464.
21. Zeng Z., et al. Overexpression of GOLPH3 promotes proliferation and tumorigenicity in breast cancer via suppression of the FOXO1 transcription factor. Clin. Cancer Res. 2012, 18(15):4059-4069.