Proteomic profile of embryonic stem cells with low survival motor neuron protein is consistent with developmental dysfunction

Journal of Neural Transmission

Volumn 124, Issue 1, 2017, Pages 13-23

  Parker, Graham C ^a,b   Carruthers, Nicholas J ^a   Gratsch, Theresa ^a   Caruso, Joseph A ^a   Stemmer, Paul M ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b iBio   (United States)

Author keywords

Mass spectrometry; Proteomics; Spinal muscular atrophy; Stem cells

Indexed keywords

EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3; GUANINE NUCLEOTIDE BINDING PROTEIN; INITIATION FACTOR; IRON REGULATORY PROTEIN 2; IRON RESPONSIVE ELEMENT BINDING PROTEIN 2; MESSENGER RNA; ODC1 PROTEIN; ORNITHINE DECARBOXYLASE; OXIDOREDUCTASE; PROTEIN; PROTEIN SPROUTY HOMOLOG 4; RIBONUCLEOPROTEIN; RIBOSOME PROTEIN; STATHMIN 2; SURVIVAL MOTOR NEURON PROTEIN; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 423; PROTEOME; SMN1 PROTEIN, MOUSE; SURVIVAL MOTOR NEURON PROTEIN 1;

ADHERENS JUNCTION; ALTERNATIVE RNA SPLICING; ARTICLE; CELL DEATH; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; EMBRYONIC STEM CELL; ENDOPLASMIC RETICULUM; FATTY ACID METABOLISM; MITOCHONDRION; MOTONEURON; PRIORITY JOURNAL; PROTEIN ACETYLATION; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEOMICS; TRANSLATIONAL PROTEIN MODIFICATION; ANIMAL; CELL CULTURE; MASS SPECTROMETRY; METABOLISM; MOUSE; SPINAL MUSCULAR ATROPHY;

ANIMALS; CELLS, CULTURED; DEVELOPMENTAL DISABILITIES; EMBRYONIC STEM CELLS; MASS SPECTROMETRY; MICE; MUSCULAR ATROPHY, SPINAL; PROTEOME; PROTEOMICS; SURVIVAL OF MOTOR NEURON 1 PROTEIN;

EID: 84965071022     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-016-1520-y     Document Type: Article

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