Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons

Brain Research

Volumn 1257, Issue , 2009, Pages 102-107

  Yua, Jixu ^a   Guo, Yansu ^a,b   Sun, Mengmeng ^a   Li, Bin ^a   Zhang, Yuesheng ^a,c   Li, Chunyan ^a,b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b Institute of Cardiocerebrovascular Disease   (China)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Glutamate excitotoxicity; Iron; Neuron degeneration; Oxidative stress

Indexed keywords

3 HYDROXYASPARTIC ACID; DEFEROXAMINE; FERRITIN; GLUTAMIC ACID; IRON; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; TRANSFERRIN RECEPTOR; 3-HYDROXYASPARTIC ACID; ASPARTIC ACID; CATION TRANSPORT PROTEIN; DRUG DERIVATIVE; IRON CHELATING AGENT; LACTATE DEHYDROGENASE; NEUROTOXIN; SOLUTE CARRIER FAMILY 11 (PROTON COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2; SOLUTE CARRIER FAMILY 11- (PROTON-COUPLED DIVALENT METAL ION TRANSPORTERS), MEMBER 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; EXCITOTOXICITY; GLUTAMATE EXCITOTOXICITY; IRON TRANSPORT; NERVE CELL DEGENERATION; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD MOTONEURON; ANALYSIS OF VARIANCE; ANIMAL; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIPID PEROXIDATION; METABOLISM; MOTONEURON; NERVE DEGENERATION; SPINAL CORD; SPRAGUE DAWLEY RAT;

RATTUS;

ANALYSIS OF VARIANCE; ANIMALS; ASPARTIC ACID; CATION TRANSPORT PROTEINS; DEFEROXAMINE; FERRITINS; GLUTAMIC ACID; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IRON; IRON CHELATING AGENTS; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; MOTOR NEURONS; NERVE DEGENERATION; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TRANSFERRIN; SPINAL CORD;

EID: 63349089476     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.12.030     Document Type: Article

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