Multi-nutrient fortification of human milk for preterm infants

Cochrane Database of Systematic Reviews

Volumn 2016, Issue 5, 2016, Pages

  Brown, Jennifer Ve ^a   Embleton, Nicholas D ^b   Harding, Jane E ^c   Mcguire, William ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL MILK; BODY HEIGHT; BODY WEIGHT; BONE MINERALIZATION; BREAST FEEDING; BREAST MILK; CHILD DEVELOPMENT; CHILD GROWTH; FORTIFIED FOOD; HEAD CIRCUMFERENCE; HOSPITALIZATION; HUMAN; INFANCY; INFANT FEEDING; INFANT NUTRITION; LENGTH; LENGTH OF STAY; MENTAL DEVELOPMENT; NECROTIZING ENTEROCOLITIS; NUTRITIONAL INTOLERANCE; PREMATURITY; PRIORITY JOURNAL; PSYCHOMOTOR DEVELOPMENT; REVIEW; SYSTEMATIC REVIEW; VERY LOW BIRTH WEIGHT; WEIGHT GAIN; CHEMISTRY; GROWTH, DEVELOPMENT AND AGING; META ANALYSIS; NEWBORN; RANDOMIZED CONTROLLED TRIAL (TOPIC);

FOOD, FORTIFIED; HUMANS; INFANT NUTRITIONAL PHYSIOLOGICAL PHENOMENA; INFANT, NEWBORN; INFANT, PREMATURE; MILK, HUMAN; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84965064102     PISSN: 14651858     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD000343.pub3     Document Type: Review

References (84)

1. Bhat BA, Gupta B. Effects of human milk fortification on morbidity factors in very low birth weight infants. Annals of Saudi Medicine 2001;21(5-6):292-5.
2. Bhat BA, Gupta B. Effects of human milk fortification on morbidity factors in very low birth weight infants. Annals of Saudi Medicine 2003;23(1-2):28-31. [PUBMED: 17146218]
3. Faerk J, Peitersen B, Petersen S, Michaelsen KF. Bone mineralisation in preterm infants cannot be predicted from serum alkaline phosphatase or serum phosphate. Archives of Disease in Childhood. Fetal and Neonatal Edition 2002;87:F133-6.
4. Faerk J, Petersen S, Peitersen B, Michaelsen KF. Diet and bone mineral content at term in premature infants. Pediatric Research 2000;47(1):148-56.
5. Faerk J, Petersen S, Peitersen B, Michaelsen KF. Diet, growth, and bone mineralisation in premature infants. Advances in Experimental Medicine and Biology 2001;501:479-83.
6. Gathwala G, Shaw CK, Shaw P, Batra R. Effect of fortification of breast milk on growth of preterm infants. Eastern Journal of Medicine 2012;17:30-5. [PUBMED: 17901665]
7. Gross SJ. Bone mineralization in preterm infants fed human milk with and without mineral supplementation. The Journal of Pediatrics 1987;111:450-8.
8. Gross SJ. Bone mineralization in preterm infants fed human milk with and without mineral supplementation. The Journal of Pediatrics 1987;111:450-8.
9. Lucas A, Fewtrell MS, Morley R, Lucas PJ, Baker BA, Lister G, et al. Randomized outcome trial of human milk fortification and developmental outcome in preterm infants. American Journa of Clinical Nutrition 1996;64:142-51.
10. Modanlou HD, Lim MO, Hansen JW, Sickles V. Growth, biochemical status, and mineral metabolism in very-low-birth-weight infants receiving fortified preterm human milk. Journal of Pediatric Gastroenterology and Nutrition 1986;5:762-7.
11. Mukhopadhyay K, Narnag A, Mahajan R. Effect of human milk fortification in appropriate for gestation and small for gestation preterm babies: a randomized controlled trial. Indian Pediatrics 2007;44(4):286-90. [PUBMED: 17468524]
12. Nicholl RM, Gamsu HR. Changes in growth and metabolism in very low birthweight infants fed with fortified breast milk. Acta Paediatrica 1999;88:1056-61.
13. Pettifor JM, Rajah R, Venter A, Moodley GP, Opperman L, Cavaleros M, et al. Bone mineralisation and mineral homeostasis in very low-birth-weight infants fed either human milk or fortified human milk. Journal of Pediatric Gastroenterology and Nutrition 1989;8:217-24.
14. Polberger SKT, Axelsson IA, Raeihae NCE. Growth of very low birth weight infants on varying amounts of human milk protein. Pediatric Research 1989;25(4):414-9.
15. Porcelli F, Trifiro G, Taccone F. Bone mineralization, hair mineral content, and biochemical parameters in preterm infants fed human milk, fortified human milk or formula. International Journal of Feto-Maternal Medicine 1992;5(2):82-6.
16. Wauben I, Gibson R, Atkinson S. Premature infants fed mothers' milk to 6 months corrected age demonstrate adequate growth and zinc status in the first year. Early Human Development 1999;54(2):181-94.
17. Wauben IP, Atkinson SA, Grad TL, Shah JK, Paes B. Moderate nutrient supplementation of mother's milk for preterm infants supports adequate bone mass and short-term growth: a randomized, controlled trial. The American Journal of Clinical Nutrition 1998;67:465-72.
18. Wauben IPM, Atkinson SA, Shah JK, Paes B. Growth and body composition of preterm infants: influence of nutrient fortification of mother's milk in hospital and breastfeeding post-hospital discharge. Acta Paediatrica 1998;87(7):780-5.
19. Zuckerman M, Pettifor JM. Rickets in very-low-birth-weight infants born at Baragwanath Hospital. South African Medical Journal 1994;84:216-20.
20. Abrams SA, Schanler RJ, Lee ML, Rechtman DJ, Prolcats Study Group. Greater mortality and morbidity in extremely preterm infants fed a diet containing cow milk protein products. Breastfeeding Medicine 2014;9(6):281-5.
21. Arslanoglu S, Moro GE, Ziegler EE. Preterm infants fed fortified human milk receive less protein than they need. Journal of Perinatology 2009;29:489-92.
22. Carey De, Rowe JC, Goetz CA, Horak E, Clark RM, Goldberg B. Growth and phosphorus metabolism in premature infants fed human milk, fortified human milk, or special preterm formula. American Journal of Diseases of Children 1987;141:511-5.
23. Greer FR, McCormick A. Improved bone mineralization and growth in premature infants fed fortified own mother's milk. The Journal of Pediatrics 1988;112:961-9.
24. Hair AB, Blanco CL, Moreira AG, Hawthorne KM, Lee ML, Rechtman DJ, et al. Randomized trial of human milk cream as a supplement to standard fortification of an exclusive human milk-based diet in infants 750-1250g birth weight. The Journal of Pediatrics 2014;165:915-20.
25. Kashyap S, Schulze KF, Forsyth M, Dell RB, Ramakrishnan R, Heird WC. Growth, nutrient retention, and metabolic response of low-birth-weight infants fed supplemented and unsupplemented preterm human milk. The American Journal of Clinical Nutrition 1990;52:254-62.
26. Kashyap S, Schulze KF, Ramakrishnan R, Dell RB, Forsyth M, Zucker C, et al. Growth, nutrient retention and metabolic response of low birth weight (LBW) infants fed human milk (HM). Pediatric Research 1988;23:486A.
27. Reali A, Greco F, Fanaro S, Atzei A, Puddu M, Moi M, et al. Fortification of maternal milk for very low birth weight (VLBW) pre-term neonates. Early Human Development 2010;86:S33-6.
28. Tarcan A, Gueraka B, Tiker F, Oezbek N. Influence of feeding formula and breast milk fortifier on lymphocyte subsets in very low birth weight premature newborns. Biology of the Neonate 2004;86:22-8.
29. Mills L, Modi N. Clinician enteral feeding preferences for very preterm babies in the UK. Archives of Disease in Childhood. Fetal and Neonatal Edition 2015; Vol. [Epub ahead of print]. [PUBMED: 25956669]
30. American Academy of Pediatrics Committee on Nutrition. Nutritional needs of preterm infants. In: Kleinman RE editor(s). Pediatric Nutrition Handbook. Elk Grove Village, IL: American Academy of Pediatrics, 2004:23-54.
31. Agostoni C, Buonocore G, Carnielli VP, De Curtis M, Darmaun D, Decsi T, et al. Enteral nutrient supply for preterm infants: commentary from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition Committee on Nutrition. Journal of Pediatric Gastroenterology and Nutrition 2010;50(1):85-91. [PUBMED: 19881390]
32. Arslanoglu S, Moro GE, Ziegler EE, The WAPM Working Group on Nutrition. Optimization of human milk fortification for preterm infants: new concepts and recommendations. Journal of Perinatal Medicine 2010;38(3):233-8. [PUBMED: 20184400]
33. Arslanoglu S, Corpeleijn W, Moro G, Braegger C, Campoy C, Colomb V, et al. Donor human milk for preterm infants: current evidence and research directions. Journal of Pediatric Gastroenterology and Nutrition 2013;57(4):535-42. [PUBMED: 24084373]
34. Brandt I, Sticker EJ, Lentze MJ. Catch-up growth of head circumference of very low birth weight, small for gestational age preterm infants and mental development to adulthood. The Journal of Pediatrics 2003;142(5):463-8. [PUBMED: 12756374]
35. Chawla D, Agarwal R, Deorari AK, Paul VK. Fluid and electrolyte management in term and preterm neonates. Indian Journal of Pediatrics 2008;75(3):255-9. [PUBMED: 18376094]
36. Clark RH, Thomas P, Peabody J. Extrauterine growth restriction remains a serious problem in prematurely born neonates. Pediatrics 2003;111(5):986-90. [PUBMED: 12728076]
37. Cooke RJ, Ainsworth SB, Fenton AC. Postnatal growth retardation: a universal problem in preterm infants. Archives of Disease in Childhood. Fetal and Neonatal Edition 2004;89(5):F428-30. [PUBMED: 15321963]
38. Cormack B, Sinn J, Lui K, Tudehope D. Australasian neonatal intensive care enteral nutrition survey: implications for practice. Journal of Paediatrics and Child Health 2013;49(4):E340-7. [PUBMED: 23227901]
39. de Halleux V, Rigo J. Variability in human milk composition: benefit of individualized fortification in very-low-birth-weight infants. The American Journal of Clinical Nutrition 2013;98(2):529S-35S. [PUBMED: 23824725]
40. Dusick AM, Poindexter BB, Ehrenkranz RA, Lemons JA. Growth failure in the preterm infant: can we catch up?. Seminars in Perinatology 2003;27(4):302-10. [PUBMED: 14510321]
41. Dutta S, Singh B, Chessell L, Wilson J, Janes M, McDonald K, et al. Guidelines for feeding very low birth weight infants. Nutrients 2015;7(1):423-42. [PUBMED: 25580815]
42. Ehrenkranz RA, Younes N, Lemons JA, Fanaroff AA, Donovan EF, Wright LL, et al. Longitudinal growth of hospitalized very low birth weight infants. Pediatrics 1999;104(2 Pt 1):280-9. [PUBMED: 10429008]
43. Embleton NE, Pang N, Cooke RJ. Postnatal malnutrition and growth retardation: an inevitable consequence of current recommendations in preterm infants?. Pediatrics 2001;107(2):270-3. [PUBMED: 11158457]
44. Embleton ND. Optimal protein and energy intakes in preterm infants. Early Human Development 2007;83(12):831-7. [PUBMED: 17980784]
45. Embleton ND. Early nutrition and later outcomes in preterm infants. World Review of Nutrition and Dietetics 2013;106:26-32. [PUBMED: 23428677]
46. Euser AM, Finken MJ, Keijzer-Veen MG, Hille ET, Wit JM, Dekker FW. Associations between prenatal and infancy weight gain and BMI, fat mass, and fat distribution in young adulthood: a prospective cohort study in males and females born very preterm. The American Journal of Clinical Nutrition 2005;81(2):480-7. [PUBMED: 15699238]
47. Euser AM, de Wit CC, Finken MJ, Rijken M, Wit JM. Growth of preterm born children. Hormone Research 2008;70(6):319-28. [PUBMED: 18953169]
48. Ewer AK, Yu VY. Gastric emptying in pre-term infants: the effect of breast milk fortifier. Acta Paediatrica 1996;85(9):1112-5. [PUBMED: 8888928]
49. Fenton TR, Premji SS, Al-Wassia H, Sauve RS. Higher versus lower protein intake in formula-fed low birth weight infants. The Cochrane Database of Systematic Reviews 2014;4:CD003959. [PUBMED: 24752987]
50. Fewtrell M. Early nutritional predictors of long-term bone health in preterm infants. Current Opinion in Clinical Nutrition and Metabolic Care 2011;14(3):297-301. [PUBMED: 21378555]
51. Flikweert ER, La Hei ER, De Rijke YB, Van de Ven K. Return of the milk curd syndrome. Pediatric Surgery International 2003;19(9-10):628-31. [PUBMED: 14600769]
52. Gathwala G, Shaw C, Shaw P, Yadav S, Sen J. Human milk fortification and gastric emptying in the preterm neonate. International Journal of Clinical Practice 2008;62(7):1039-43. [PUBMED: 18422595]
53. Brozek J, Oxman A, Schünemann H. GRADEpro [Version 3.2 for Windows]. The GRADE Working Group, 2008.
54. Gregory KE, Connolly TC. Enteral feeding practices in the NICU: results from a 2009 Neonatal Enteral Feeding Survey. Advances in Neonatal Care 2012;12(1):46-55. [PUBMED: 22301544]
55. Gross SJ, Slagle TA. Feeding the low birth weight infant. Clinics in Perinatology 1993;20(1):193-209. [PUBMED: 8458165]
56. Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J, et al. GRADE guidelines: 1. Introduction - GRADE evidence profiles and summary of findings tables. Journal of Clinical Epidemiology 2011;64(4):383-94. [PUBMED: 21195583]
57. Guyatt GH, Oxman AD, Vist G, Kunz R, Brozek J, Alonso-Coello P, et al. GRADE guidelines: 4. Rating the quality of evidence - study limitations (risk of bias). Journal of Clinical Epidemiology 2011;64(4):407-15. [PUBMED: 21247734]
58. Guyatt GH, Oxman AD, Kunz R, Brozek J, Alonso-Coello P, Rind D, et al. GRADE guidelines 6. Rating the quality of evidence - imprecision. Journal of Clinical Epidemiology 2011;64(12):1283-93. [PUBMED: 21839614]
59. Guyatt GH, Oxman AD, Kunz R, Woodcock J, Brozek J, Helfand M, et al. GRADE guidelines: 7. Rating the quality of evidence - inconsistency. Journal of Clinical Epidemiology 2011;64(12):1294-302. [PUBMED: 21803546]
60. Guyatt GH, Oxman AD, Kunz R, Woodcock J, Brozek J, Helfand M, et al. GRADE guidelines: 8. Rating the quality of evidence - indirectness. Journal of Clinical Epidemiology 2011;64(12):1303-10. [PUBMED: 21802903]
61. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. www.cochrane-handbook.org.
62. Imdad A, Bhutta ZA. Nutritional management of the low birth weight/preterm infant in community settings: a perspective from the developing world. The Journal of Pediatrics March 2013;162(3):s107-114.
63. Johnston M, Landers S, Noble L, Szucs K, Viehmann L. Breastfeeding and the use of human milk. Pediatrics 2012;129(3):e827-41. [PUBMED: 22371471]
64. Kashyap S, Schulze KF, Ramakrishnan R, Dell RB, Heird WC. Evaluation of a mathematical model for predicting the relationship between protein and energy intakes of low-birth-weight infants and the rate and composition of weight gain. Pediatric Research 1994;35(6):704-12. [PUBMED: 7936823]
65. Kler N, Thakur A, Modi M, Kaur A, Garg P, Soni A, et al. Human milk fortification in India. Nestle Nutrition Institute Workshop Series 2015;81:145-51. [PUBMED: 26111571]
66. Klingenberg C, Embleton ND, Jacobs SE, O'Connell LA, Kuschel CA. Enteral feeding practices in very preterm infants: an international survey. Archives of Disease in Childhood. Fetal and Neonatal Edition 2012;97(1):F56-61. [PUBMED: 21856644]
67. Lapillonne A, Griffin IJ. Feeding preterm infants today for later metabolic and cardiovascular outcomes. The Journal of Pediatrics 2013;162(3 Suppl):S7-16. [PUBMED: 23445851]
68. Leppanen M, Lapinleimu H, Lind A, Matomaki J, Lehtonen L, Haataja L, et al. Antenatal and postnatal growth and 5-year cognitive outcome in very preterm infants. Pediatrics 2014;133(1):63-70. [PUBMED: 24344103]
69. McClure RJ, Newell SJ. Effect of fortifying breast milk on gastric emptying. Archives of Disease in Childhood. Fetal and Neonatal Edition 1996;74(1):F60-2. [PUBMED: 8653439]
70. Morgan JA, Young L, McGuire W. Pathogenesis and prevention of necrotizing enterocolitis. Current Opinion in Infectious Diseases 2011;24(3):183-9. [PUBMED: 21455063]
71. Moya F, Sisk PM, Walsh KR, Berseth CL. A new liquid human milk fortifier and linear growth in preterm infants. Pediatrics 2012;130(4):e928-35. [PUBMED: 22987877]
72. Rochow N, Fusch G, Choi A, Chessell L, Elliott L, McDonald K, et al. Target fortification of breast milk with fat, protein, and carbohydrates for preterm infants. The Journal of Pediatrics 2013;163(4):1001-7. [PUBMED: 23769498]
73. Rochow N, Landau-Crangle E, Fusch C. Challenges in breast milk fortification for preterm infants. Current Opinion in Clinical Nutrition and Metabolic Care 2015;18(3):276-84. [PUBMED: 25807355]
74. Schünemann H, Brozek J, Guyatt G, Oxman A, editors. GWG . GRADE Handbook for Grading Quality of Evidence and Strength of Recommendations. www.guidelinedevelopment.org/handbook. Updated October 2013.
75. Singhal A, Cole TJ, Fewtrell M, Kennedy K, Stephenson T, Elias-Jones A, et al. Promotion of faster weight gain in infants born small for gestational age: is there an adverse effect on later blood pressure?. Circulation 2007;115(2):213-20.
76. Stanger J, Zwicker K, Albersheim S, Murphy JJ 3rd. Human milk fortifier: an occult cause of bowel obstruction in extremely premature neonates. Journal of Pediatric Surgery 2014;49(5):724-6. [PUBMED: 24851756]
77. Steward DK, Pridham KF. Growth patterns of extremely low-birth-weight hospitalized preterm infants. Journal of Obstetric, Gynecologic, and Neonatal Nursing 2002;31(1):57-65. [PUBMED: 11843020]
78. Tinnion RJ, Embleton ND. How to use.. alkaline phosphatase in neonatology. Archives of Disease in Childhood. Education and Practice Edition 2012;97(4):157-63. [PUBMED: 22761487]
79. Tudehope DI. Human milk and the nutritional needs of preterm infants. The Journal of Pediatrics 2013;162:S17-25.
80. Wagener S, Cartwright D, Bourke C. Milk curd obstruction in premature infants receiving fortified expressed breast milk. Journal of Paediatrics and Child Health 2009;45(4):228-30. [PUBMED: 19426380]
81. Walsh MC, Kliegman RM. Necrotizing enterocolitis: treatment based on staging criteria. Pediatric Clinics of North America 1986;33(1):179-201. [PUBMED: 3081865]
82. Yigit S, Akgoz A, Memisoglu A, Akata D, Ziegler EE. Breast milk fortification: effect on gastric emptying. The Journal of Maternal-Fetal & Neonatal Medicine 2008;21(11):843-6. [PUBMED: 18985557]
83. Kuschel CA, Harding JE. Multicomponent fortified human milk for promoting growth in preterm infants. Cochrane Database of Systematic Reviews 2004, Issue 1. [DOI: 10.1002/14651858.CD000343; PUBMED: 14973953]
84. Kuschel CA, Harding JE. Multicomponent fortified human milk for promoting growth in preterm infants. Cochrane Database of Systematic Reviews 2009, Issue 1. [DOI: 10.1002/14651858.CD000343.pub2]