Defective mutations within the translocation domain of Clostridium difficile toxin B impair disease pathogenesis

Pathogens and Disease

Volumn 74, Issue 1, 2018, Pages

  Hamza, Therwa ^a   Zhang, Zhifen ^b   Melnyk, Roman A ^b,c   Feng, Hanping ^a  

^a UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Clostridium difficile; TcdB; Toxin; Translocation domain

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL TOXIN; PORE FORMING CYTOTOXIC PROTEIN; TOXB PROTEIN, CLOSTRIDIUM DIFFICILE; VIRULENCE FACTOR;

ANIMAL; CLOSTRIDIUM INFECTION; DISEASE MODEL; DNA MUTATIONAL ANALYSIS; FEMALE; GENETICS; INTOXICATION; METABOLISM; MICROBIOLOGY; MOUSE; MUTATION; PATHOGENICITY; PATHOLOGY; PEPTOCLOSTRIDIUM DIFFICILE; PROTEIN TRANSPORT; SURVIVAL ANALYSIS;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM INFECTIONS; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; FEMALE; MICE; MUTATION; POISONING; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN TRANSPORT; SURVIVAL ANALYSIS; VIRULENCE FACTORS;

EID: 84965051355     PISSN: None     EISSN: 2049632X     Source Type: Journal    
DOI: 10.1093/femspd/ftv098     Document Type: Article

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