Revealing the activation pathway for TMEM16A chloride channels from macroscopic currents and kinetic models

Pflugers Archiv European Journal of Physiology

Volumn 468, Issue 7, 2016, Pages 1241-1257

  Contreras Vite, Juan A ^a   Cruz Rangel, Silvia ^a   De Jesús Pérez, José J ^a   Figueroa, Iván A Aréchiga ^a   Rodríguez Menchaca, Aldo A ^a   Pérez Cornejo, Patricia ^a   Hartzell, H Criss ^b   Arreola, Jorge ^a  

^a UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chloride channel; Gating; Kinetics; Mathematical modelling; Patch clamp; Permeation

Indexed keywords

CALCIUM; CALCIUM ACTIVATED CHLORIDE CHANNEL; TANNIN; TMEM16A PROTEIN; UNCLASSIFIED DRUG; ANION; ANO1 PROTEIN, HUMAN; CHLORIDE; CHLORIDE CHANNEL; TUMOR PROTEIN;

ARTICLE; CALCIUM BINDING; CALCIUM CELL LEVEL; CELL ACTIVATION; CHANNEL GATING; CHLORIDE CONDUCTANCE; CHLORIDE CURRENT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEPOLARIZATION; EMBRYO; HUMAN; HUMAN CELL; ION PERMEABILITY; MARKOV CHAIN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPOLARIZATION; TRANSPORT KINETICS; ANIMAL; CELL LINE; HEK293 CELL LINE; KINETICS; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE CELL;

ANIMALS; ANIONS; CALCIUM; CELL LINE; CHLORIDE CHANNELS; CHLORIDES; HEK293 CELLS; HUMANS; ION CHANNEL GATING; KINETICS; MICE; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; NEOPLASM PROTEINS;

EID: 84965006784     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-016-1830-9     Document Type: Article

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