The Geropathology research network: An interdisciplinary approach for integrating pathology into research on aging

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 71, Issue 4, 2016, Pages 431-434

  Ladiges, Warren ^a   Ikeno, Yuji ^b   Niedernhofer, Laura ^c   Mcindoe, Richard A ^d   Ciol, Marcia A ^e   Ritchey, Jerry ^f   Liggitt, Denny ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^c Department of Metabolism and Aging ^*  (United States)

^d AUGUSTA UNIVERSITY   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

Aging; Geropathology; Geropathology research network; Health Span; Healthy aging; Histopathology; Life; Molecular pathology; Span

Indexed keywords

AGED; AGING; ANIMAL; BIOLOGY; GERIATRICS; HUMAN; MEDICAL RESEARCH; ORGANIZATION; PATHOLOGY; STATISTICS; TRENDS;

AGED; AGING; ANIMALS; BIOMEDICAL RESEARCH; COMPUTATIONAL BIOLOGY; CONGRESSES AS TOPIC; GERIATRICS; HUMANS; ORGANIZATIONAL OBJECTIVES; PATHOLOGY; STATISTICS AS TOPIC;

EID: 84964857622     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glv079     Document Type: Review

References (23)

1. Ladiges W, Ikeno Y, Liggitt D, Treuting PM. Pathology is a critical aspect of preclinical aging studies. Pathobiol Aging Age Relat Dis. 2013;3:1-4. doi:10.3402/pba.v3i0.22451.
2. Schriner SE, Linford NJ, Martin GM, et al. Extension of murine life span by overexpression of catalase targeted to mitochondria. Science. 2005;308:1909-1911.
3. Liang H, Masoro EJ, Nelson JF, Strong R, McMahan CA, Richardson A. Genetic mouse models of extended lifespan. Exp Gerontol. 2003;38:1353- 1364.
4. Amador-Noguez D, Yagi K, Venable S, Darlington G. Gene expression profile of long-lived Ames dwarf mice and Little mice. Aging Cell. 2004;3:423-441.
5. Flurkey K, Astle CM, Harrison DE. Life extension by diet restriction and N- Acetyl-L-cysteine in genetically heterogeneous mice. J Gerontol A Biol Sci Med Sci. 2010;65:1275-1284. doi:10.1093/gerona/glq155.
6. Miller RA, Harrison DE, Astle CM, et al. An Aging Interventions Testing Program: study design and interim report. Aging Cell. 2007;6:565-575.
7. Nadon NL, Strong R, Miller RA, et al. Design of aging intervention studies: The NIA interventions testing program. Age (Dordr). 2008;30:187-199. doi:10.1007/s11357-008-9048-1.
8. Adissu HA, Estabel J, Sunter D, et al. Histopathology reveals correlative and unique phenotypes in a high- Throughput mouse phenotyping screen. Dis Model Mech. 2014;7:515-524. doi:10.1242/dmm.015263.
9. Schofield PN, Dubus P, Klein L, et al. Pathology of the laboratory mouse: An International Workshop on Challenges for High Throughput Phenotyping. Toxicol Pathol. 2011;39:559-562. doi:10.1177/0192623311399789.
10. Warren MV, Studley ML, Dubus P, et al. An impending crisis in the provision of histopathology expertise for mouse functional genomics. J Pathol. 2009;217:4-13. doi:10.1002/path.2460.
11. Ladiges W, Van Remmen, H, Strong R, et al. Lifespan extension in genetically modified mice. Aging Cell. 2009;8:346-352. doi:10.1111/j.1474-9726.2009.00491.x.
12. Sundberg JP, Berndt A, Sundberg BA, et al. The mouse as a model for understanding chronic diseases of aging: The histopathologic basis of aging in inbred mice. Pathobiol Aging Age Relat Dis. 2011;1-9. doi:10.3402/pba.v1i0.7179.
13. Ruehl-Fehlert C, Kittel B, Morawietz G, et al. Revised guides for organ sampling and trimming in rats and mice-part 1. Exp Toxicol Pathol. 2003;55:91-106.
14. Kittel B, Ruehl-Fehlert C, Morawietz G, et al. Revised guides for organ sampling and trimming in rats and mice-part 2. A joint publication of the RITA and NACAD groups. Exp Toxicol Pathol. 2004;55:413-431.
15. Morawietz G, Ruehl-Fehlert C, Kittel B, et al. Revised guides for organ sampling and trimming in rats and mice-part 3. A joint publication of the RITA and NACAD groups. Exp Toxicol Pathol. 2004;55:433-449.
16. Gibson-Corley KN, Olivier AK, Meyerholz DK. Principles for valid histopathologic scoring in research. Vet Pathol. 2013;50:1007-1015. doi:10.1177/0300985813485099.
17. Ikeno Y, Bronson RT, Hubbard GB, Lee S, Bartke A. Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity. J Gerontol A Biol Sci Med Sci. 2003;58:291-296.
18. Treuting PM, Linford NJ, Knoblaugh SE, et al. Reduction of age- Associated pathology in old mice by overexpression of catalase in mitochondria. J Gerontol A Biol Sci Med Sci. 2008;63:813-822.
19. Schofield PN, Gruenberger M, Sundberg JP. Pathbase and the MPATH ontology. Community resources for mouse histopathology. Vet Pathol. 2010;47:1016-1020. doi:10.1177/0300985810374845.
20. Schofield PN, Sundberg JP, Sundberg BA, McKerlie C, Gkoutos GV. The mouse pathology ontology, MPATH; structure and applications. J Biomed Semantics. 2013;4:18-34. doi:10.1186/2041-1480-4-18.
21. Mallon AM, Blake A, Hancock JM. EuroPhenome and EMPReSS: online mouse phenotyping resource. Nucleic Acids Res. 2008;36:D715-D718.
22. Pettan-Brewer C, Treuting PM. Practical pathology of aging mice. Pathobiol Aging Age Relat Dis. 2011;1:1-16. doi:10.3402/pba.v1i0.7202.
23. Scudamore CL. Integrating pathology into human disease modelling-how to eat the elephant. Dis Model Mech. 2014;7:495-497. doi:10.1242/dmm.016394.