Control for Population Structure and Relatedness for Binary Traits in Genetic Association Studies via Logistic Mixed Models

American Journal of Human Genetics

Volumn 98, Issue 4, 2016, Pages 653-666

  Chen, Han ^a   Wang, Chaolong ^a,b   Conomos, Matthew P ^c   Stilp, Adrienne M ^c   Li, Zilin ^a,d   Sofer, Tamar ^c   Szpiro, Adam A ^c   Chen, Wei ^e   Brehm, John M ^e   Celedón, Juan C ^e   Redline, Susan ^f   Papanicolaou, George J ^g   Thornton, Timothy A ^c   Laurie, Cathy C ^c   Rice, Kenneth ^c   Lin, Xihong ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

^c UNIVERSITY OF WASHINGTON   (United States)

^d TSINGHUA UNIVERSITY   (China)

^e CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ASTHMA; CONTROLLED STUDY; GENETIC ASSOCIATION; GENETIC TRAIT; GENETIC VARIABILITY; GENOMICS; GENOTYPE; HUMAN; MATHEMATICAL MODEL; POPULATION STRUCTURE; PRIORITY JOURNAL; SIMULATION; BIOLOGICAL MODEL; CASE CONTROL STUDY; CENTRAL AMERICA; COMPUTER SIMULATION; GENETIC ASSOCIATION STUDY; GENETICS; GENOTYPING TECHNIQUE; PHENOTYPE; PHYLOGEOGRAPHY; POPULATION GENETICS; PROCEDURES; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AMERICA; STATISTICAL MODEL;

ASTHMA; CASE-CONTROL STUDIES; CENTRAL AMERICA; COMPUTER SIMULATION; GENETIC ASSOCIATION STUDIES; GENETICS, POPULATION; GENOTYPING TECHNIQUES; HUMANS; LINEAR MODELS; LOGISTIC MODELS; MODELS, GENETIC; PHENOTYPE; PHYLOGEOGRAPHY; POLYMORPHISM, SINGLE NUCLEOTIDE; SOUTH AMERICA;

EID: 84964829120     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2016.02.012     Document Type: Article

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