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Volumn 45, Issue 2, 2013, Pages 208-213

Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

(51)  Fakiola, Michaela a   Strange, Amy b   Cordell, Heather J c   Miller, E Nancy a   Pirinen, Matti b   Su, Zhan b   Mishra, Anshuman d   Mehrotra, Sanjana d   Monteiro, Gloria R e   Band, Gavin b   Bellenguez, Céline b   Dronov, Serge f   Edkins, Sarah f   Freeman, Colin b   Giannoulatou, Eleni b   Gray, Emma f   Hunt, Sarah E f   Lacerda, Henio G e   Langford, Cordelia f   Pearson, Richard b   more..


Author keywords

[No Author keywords available]

Indexed keywords

CCL1 CHEMOKINE; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; HLA ANTIGEN CLASS 2; HLA DQA1 ANTIGEN; HLA DRB1 ANTIGEN; INTERLEUKIN 2 RECEPTOR BETA;

EID: 84873088400     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2518     Document Type: Article
Times cited : (89)

References (66)
  • 1
    • 84861665791 scopus 로고    scopus 로고
    • Leishmaniasis worldwide and global estimates of its incidence
    • Alvar, J. et al. Leishmaniasis worldwide and global estimates of its incidence. PLoS ONE 7, e35671 (2012).
    • (2012) PLoS ONE , vol.7
    • Alvar, J.1
  • 2
    • 18744387204 scopus 로고    scopus 로고
    • The interplay between environmental and host factors during an outbreak of visceral leishmaniasis in eastern Sudan
    • Bucheton, B. et al. The interplay between environmental and host factors during an outbreak of visceral leishmaniasis in eastern Sudan. Microbes Infect. 4, 1449-1457 (2002).
    • (2002) Microbes Infect , vol.4 , pp. 1449-1457
    • Bucheton, B.1
  • 4
    • 0020422819 scopus 로고
    • Prevalence and disease spectrum in a new focus of visceral leishmaniasis in Kenya
    • Ho, M., Siongok, T.K., Lyerly, W.H. & Smith, D.H. Prevalence and disease spectrum in a new focus of visceral leishmaniasis in Kenya. Trans. R. Soc. Trop. Med. Hyg. 76, 741-746 (1982).
    • (1982) Trans. R. Soc. Trop. Med. Hyg , vol.76 , pp. 741-746
    • Ho, M.1    Siongok, T.K.2    Lyerly, W.H.3    Smith, D.H.4
  • 5
    • 0029033440 scopus 로고
    • Familial aggregation of Leishmnaia chagasi infection in northeastern Brazil
    • Cabello, P.H., Lima, A.M., Azevedo, E.S. & Kriger, H. Familial aggregation of Leishmnaia chagasi infection in northeastern Brazil. Am. J. Trop. Med. Hyg. 52, 364-365 (1995).
    • (1995) Am. J. Trop. Med. Hyg , vol.52 , pp. 364-365
    • Cabello, P.H.1    Lima, A.M.2    Azevedo, E.S.3    Kriger, H.4
  • 6
    • 0035085579 scopus 로고    scopus 로고
    • Genetic epidemiology of visceral leishmaniasis in northeastern Brazil
    • Peacock, C.S. et al. Genetic epidemiology of visceral leishmaniasis in northeastern Brazil. Genet. Epidemiol. 20, 383-396 (2001).
    • (2001) Genet. Epidemiol , vol.20 , pp. 383-396
    • Peacock, C.S.1
  • 7
    • 33748902565 scopus 로고    scopus 로고
    • Genetic susceptibility to infectious diseases: Big is beautiful, but will bigger be even better?
    • Burgner, D., Jamieson, S.E. & Blackwell, J.M. Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better? Lancet Infect. Dis. 6, 653-663 (2006).
    • (2006) Lancet Infect. Dis , vol.6 , pp. 653-663
    • Burgner, D.1    Jamieson, S.E.2    Blackwell, J.M.3
  • 8
    • 64549109000 scopus 로고    scopus 로고
    • Genetics and visceral leishmaniasis: Of mice and man
    • Blackwell, J.M. et al. Genetics and visceral leishmaniasis: of mice and man. Parasite Immunol. 31, 254-266 (2009).
    • (2009) Parasite Immunol , vol.31 , pp. 254-266
    • Blackwell, J.M.1
  • 10
    • 35348853743 scopus 로고    scopus 로고
    • Genetic predisposition to self-curing infection with the protozoan Leishmania chagasi: A genomewide scan
    • Jeronimo, S.M. et al. Genetic predisposition to self-curing infection with the protozoan Leishmania chagasi: a genomewide scan. J. Infect. Dis. 196, 1261-1269 (2007).
    • (2007) J. Infect. Dis , vol.196 , pp. 1261-1269
    • Jeronimo, S.M.1
  • 11
    • 65449121475 scopus 로고    scopus 로고
    • Genetic admixture in Brazilians exposed to infection with Leishmania chagasi
    • Ettinger, N.A. et al. Genetic admixture in Brazilians exposed to infection with Leishmania chagasi. Ann. Hum. Genet. 73, 304-313 (2009).
    • (2009) Ann. Hum. Genet , vol.73 , pp. 304-313
    • Ettinger, N.A.1
  • 12
    • 84855177237 scopus 로고    scopus 로고
    • A robust clustering algorithm for identifying problematic samples in genome-wide association studies
    • Bellenguez, C., Strange, A., Freeman, C., Donnelly, P. & Spencer, C.C. A robust clustering algorithm for identifying problematic samples in genome-wide association studies. Bioinformatics 28, 134-135 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 134-135
    • Bellenguez, C.1    Strange, A.2    Freeman, C.3    Donnelly, P.4    Spencer, C.C.5
  • 13
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • Sawcer, S. et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476, 214-219 (2011).
    • (2011) Nature , vol.476 , pp. 214-219
    • Sawcer, S.1
  • 14
    • 77955166399 scopus 로고    scopus 로고
    • Population structure and cryptic relatedness in genetic association studies
    • Astle, W. & Balding, D.J. Population structure and cryptic relatedness in genetic association studies. Stat. Sci. 24, 451-471 (2009).
    • (2009) Stat. Sci , vol.24 , pp. 451-471
    • Astle, W.1    Balding, D.J.2
  • 15
    • 80053372166 scopus 로고    scopus 로고
    • FaST linear mixed models for genome-wide association studies
    • Lippert, C. et al. FaST linear mixed models for genome-wide association studies. Nat. Methods 8, 833-835 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 833-835
    • Lippert, C.1
  • 16
    • 77950299137 scopus 로고    scopus 로고
    • Mixed linear model approach adapted for genome-wide association studies
    • Zhang, Z. et al. Mixed linear model approach adapted for genome-wide association studies. Nat. Genet. 42, 355-360 (2010).
    • (2010) Nat. Genet , vol.42 , pp. 355-360
    • Zhang, Z.1
  • 17
    • 77950301214 scopus 로고    scopus 로고
    • Variance component model to account for sample structure in genome-wide association studies
    • Kang, H.M. et al. Variance component model to account for sample structure in genome-wide association studies. Nat. Genet. 42, 348-354 (2010).
    • (2010) Nat. Genet , vol.42 , pp. 348-354
    • Kang, H.M.1
  • 18
    • 44249112333 scopus 로고    scopus 로고
    • A genomic background based method for association analysis in related individuals
    • Amin, N., van Duijn, C.M. & Aulchenko, Y.S. A genomic background based method for association analysis in related individuals. PLoS ONE 2, e1274 (2007).
    • (2007) PLoS ONE , vol.2
    • Amin, N.1    Van Duijn, C.M.2    Aulchenko, Y.S.3
  • 19
    • 83455195449 scopus 로고    scopus 로고
    • Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India
    • Mehrotra, S. et al. Genetic and functional evaluation of the role of CXCR1 and CXCR2 in susceptibility to visceral leishmaniasis in north-east India. BMC Med. Genet. 12, 162 (2011).
    • (2011) BMC Med. Genet , vol.12 , pp. 162
    • Mehrotra, S.1
  • 20
    • 33846484813 scopus 로고    scopus 로고
    • Identification of a novel G245R polymorphism in the IL-2 receptor β membrane proximal domain associated with human visceral leishmaniasis
    • Bucheton, B. et al. Identification of a novel G245R polymorphism in the IL-2 receptor β membrane proximal domain associated with human visceral leishmaniasis. Genes Immun. 8, 79-83 (2007).
    • (2007) Genes Immun , vol.8 , pp. 79-83
    • Bucheton, B.1
  • 21
    • 33846485608 scopus 로고    scopus 로고
    • Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil
    • Jamieson, S.E. et al. Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil. Genes Immun. 8, 84-90 (2007).
    • (2007) Genes Immun , vol.8 , pp. 84-90
    • Jamieson, S.E.1
  • 22
    • 79960109781 scopus 로고    scopus 로고
    • Genetic and functional evidence implicating DLL1 as the gene that influences susceptibility to visceral leishmaniasis at chromosome 6q27
    • Fakiola, M. et al. Genetic and functional evidence implicating DLL1 as the gene that influences susceptibility to visceral leishmaniasis at chromosome 6q27. J. Infect. Dis. 204, 467-477 (2011).
    • (2011) J. Infect. Dis , vol.204 , pp. 467-477
    • Fakiola, M.1
  • 23
    • 10744230828 scopus 로고    scopus 로고
    • SLC11A1 (formerly NRAMP1) and susceptibility to visceral leishmaniasis in the Sudan
    • Mohamed, H.S. et al. SLC11A1 (formerly NRAMP1) and susceptibility to visceral leishmaniasis in The Sudan. Eur. J. Hum. Genet. 12, 66-74 (2004).
    • (2004) Eur. J. Hum. Genet , vol.12 , pp. 66-74
    • Mohamed, H.S.1
  • 24
    • 79960279940 scopus 로고    scopus 로고
    • Promise and pitfalls of the Immunochip
    • Cortes, A. & Brown, M.A. Promise and pitfalls of the Immunochip. Arthritis Res. Ther. 13, 101 (2011).
    • (2011) Arthritis Res. Ther , vol.13 , pp. 101
    • Cortes, A.1    Brown, M.A.2
  • 25
    • 33749137515 scopus 로고    scopus 로고
    • A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
    • de Bakker, P.I. et al. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat. Genet. 38, 1166-1172 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 1166-1172
    • De Bakker, P.I.1
  • 26
    • 0030906824 scopus 로고    scopus 로고
    • Circulating T helper 1 (Th1) cell-and Th2 cell-associated cytokines in Indian patients with visceral leishmaniasis
    • Sundar, S., Reed, S.G., Sharma, S., Mehrotra, A. & Murray, H.W. Circulating T helper 1 (Th1) cell-and Th2 cell-associated cytokines in Indian patients with visceral leishmaniasis. Am. J. Trop. Med. Hyg. 56, 522-525 (1997).
    • (1997) Am. J. Trop. Med. Hyg , vol.56 , pp. 522-525
    • Sundar, S.1    Reed, S.G.2    Sharma, S.3    Mehrotra, A.4    Murray, H.W.5
  • 27
    • 0026585442 scopus 로고
    • Immunologic markers of clinical evolution in children recently infected with Leishmania donovani chagasi
    • Carvalho, E.M. et al. Immunologic markers of clinical evolution in children recently infected with Leishmania donovani chagasi. J. Infect. Dis. 165, 535-540 (1992).
    • (1992) J. Infect. Dis , vol.165 , pp. 535-540
    • Carvalho, E.M.1
  • 28
    • 0035026916 scopus 로고    scopus 로고
    • Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis
    • Meddeb-Garnaoui, A. et al. Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis. Hum. Immunol. 62, 509-517 (2001).
    • (2001) Hum. Immunol , vol.62 , pp. 509-517
    • Meddeb-Garnaoui, A.1
  • 29
    • 79959861777 scopus 로고    scopus 로고
    • Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin
    • Kuhls, K. et al. Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin. PLoS Negl. Trop. Dis. 5, e1155 (2011).
    • (2011) PLoS Negl. Trop. Dis , vol.5
    • Kuhls, K.1
  • 30
    • 18844466661 scopus 로고    scopus 로고
    • Role of HLA class II alleles in susceptibility to and protection from localized cutaneous leishmaniasis
    • Olivo-Díaz, A. et al. Role of HLA class II alleles in susceptibility to and protection from localized cutaneous leishmaniasis. Hum. Immunol. 65, 255-261 (2004).
    • (2004) Hum. Immunol , vol.65 , pp. 255-261
    • Olivo-Díaz, A.1
  • 31
    • 0028832278 scopus 로고
    • Polymorphism in TNF genes associated with mucocutaneous leishmaniasis
    • Cabrera, M. et al. Polymorphism in TNF genes associated with mucocutaneous leishmaniasis. J. Exp. Med. 182, 1259-1264 (1995).
    • (1995) J. Exp. Med , vol.182 , pp. 1259-1264
    • Cabrera, M.1
  • 33
    • 67349278465 scopus 로고    scopus 로고
    • Genome-wide and fine-resolution association analysis of malaria in West Africa
    • Jallow, M. et al. Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat. Genet. 41, 657-665 (2009).
    • (2009) Nat. Genet , vol.41 , pp. 657-665
    • Jallow, M.1
  • 34
    • 77956635151 scopus 로고    scopus 로고
    • Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2
    • Thye, T. et al. Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. Nat. Genet. 42, 739-741 (2010).
    • (2010) Nat. Genet , vol.42 , pp. 739-741
    • Thye, T.1
  • 35
    • 80055010567 scopus 로고    scopus 로고
    • Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1
    • Khor, C.C. et al. Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. Nat. Genet. 43, 1139-1141 (2011).
    • (2011) Nat. Genet , vol.43 , pp. 1139-1141
    • Khor, C.C.1
  • 36
    • 74049127960 scopus 로고    scopus 로고
    • Genomewide association study of leprosy
    • Zhang, F.R. et al. Genomewide association study of leprosy. N. Engl. J. Med. 361, 2609-2618 (2009).
    • (2009) N. Engl. J. Med , vol.361 , pp. 2609-2618
    • Zhang, F.R.1
  • 37
    • 33750575944 scopus 로고    scopus 로고
    • Knowledge attitude, and practices related to Kala-azar in a rural area of Bihar state India
    • Singh, S.P., Reddy, D.C., Mishra, R.N. & Sundar, S. Knowledge, attitude, and practices related to Kala-azar in a rural area of Bihar state, India. Am. J. Trop. Med. Hyg. 75, 505-508 (2006).
    • (2006) Am. J. Trop. Med. Hyg , vol.75 , pp. 505-508
    • Singh, S.P.1    Reddy, D.C.2    Mishra, R.N.3    Sundar, S.4
  • 38
    • 22244481600 scopus 로고    scopus 로고
    • The molecular characterization of clinical isolates from Indian Kala-azar patients by MLEE and RAPD-PCR
    • Manna, M., Majumder, H.K., Sundar, S. & Bhaduri, A.N. The molecular characterization of clinical isolates from Indian Kala-azar patients by MLEE and RAPD-PCR. Med. Sci. Monit. 11, BR220-BR227 (2005).
    • (2005) Med. Sci. Monit , vol.11
    • Manna, M.1    Majumder, H.K.2    Sundar, S.3    Bhaduri, A.N.4
  • 39
    • 0028845084 scopus 로고
    • Recent kala-azar cases in India: Isozyme profiles of Leishmania parasites
    • Chatterjee, M., Manna, M., Bhaduri, A.N. & Sarkar, D. Recent kala-azar cases in India: isozyme profiles of Leishmania parasites. Indian J. Med. Res. 102, 165-172 (1995).
    • (1995) Indian J. Med. Res , vol.102 , pp. 165-172
    • Chatterjee, M.1    Manna, M.2    Bhaduri, A.N.3    Sarkar, D.4
  • 40
    • 0035295431 scopus 로고    scopus 로고
    • Leishmania species, drug unresponsiveness and visceral leishmaniasis in Bihar, India
    • Thakur, C.P., Dedet, J.P., Narain, S. & Pratlong, F. Leishmania species, drug unresponsiveness and visceral leishmaniasis in Bihar, India. Trans. R. Soc. Trop. Med. Hyg. 95, 187-189 (2001).
    • (2001) Trans. R. Soc. Trop. Med. Hyg , vol.95 , pp. 187-189
    • Thakur, C.P.1    Dedet, J.P.2    Narain, S.3    Pratlong, F.4
  • 41
    • 0034855527 scopus 로고    scopus 로고
    • Resistance to treatment in Kala-azar: Speciation of isolates from northeast India
    • Sundar, S. et al. Resistance to treatment in Kala-azar: speciation of isolates from northeast India. Am. J. Trop. Med. Hyg. 65, 193-196 (2001).
    • (2001) Am. J. Trop. Med. Hyg , vol.65 , pp. 193-196
    • Sundar, S.1
  • 42
    • 0031590296 scopus 로고    scopus 로고
    • Immunogenetics of leishmanial and mycobacterial infections: The Belem Family Study
    • Blackwell, J.M. et al. Immunogenetics of leishmanial and mycobacterial infections: the Belem Family Study. Phil. Trans. R. Soc. Lond. B 352, 1331-1345 (1997).
    • (1997) Phil. Trans. R. Soc. Lond B , vol.352 , pp. 1331-1345
    • Blackwell, J.M.1
  • 43
    • 4143129899 scopus 로고    scopus 로고
    • An emerging peri-urban pattern of infection with Leishmania chagasi, the protozoan causing visceral leishmaniasis in northeast Brazil
    • Jeronimo, S.M. et al. An emerging peri-urban pattern of infection with Leishmania chagasi, the protozoan causing visceral leishmaniasis in northeast Brazil. Scand. J. Infect. Dis. 36, 443-449 (2004).
    • (2004) Scand. J. Infect. Dis , vol.36 , pp. 443-449
    • Jeronimo, S.M.1
  • 44
    • 0036165504 scopus 로고    scopus 로고
    • Epidemiology and clinical manifestations of Leishmania donovani infection in two villages in an endemic area in eastern Sudan
    • Khalil, E.A., Zijlstra, E.E., Kager, P.A. & El Hassan, A.M. Epidemiology and clinical manifestations of Leishmania donovani infection in two villages in an endemic area in eastern Sudan. Trop. Med. Int. Health 7, 35-44 (2002).
    • (2002) Trop. Med. Int. Health , vol.7 , pp. 35-44
    • Khalil, E.A.1    Zijlstra, E.E.2    Kager, P.A.3    El Hassan, A.M.4
  • 45
    • 79251523859 scopus 로고    scopus 로고
    • Classification and regression tree and spatial analyses reveal geographic heterogeneity in genome wide linkage study of Indian visceral leishmaniasis
    • Fakiola, M. et al. Classification and regression tree and spatial analyses reveal geographic heterogeneity in genome wide linkage study of Indian visceral leishmaniasis. PLoS ONE 5, e15807 (2010).
    • (2010) PLoS ONE , vol.5
    • Fakiola, M.1
  • 46
    • 0028568490 scopus 로고
    • Endemic kala-azar in eastern Sudan: A longitudinal study on the incidence of clinical and subclinical infection and post-kala-azar dermal leishmaniasis
    • Zijlstra, E.E., el-Hassan, A.M., Ismael, A. & Ghalib, H.W. Endemic kala-azar in eastern Sudan: a longitudinal study on the incidence of clinical and subclinical infection and post-kala-azar dermal leishmaniasis. Am. J. Trop. Med. Hyg. 51, 826-836 (1994).
    • (1994) Am. J. Trop. Med. Hyg , vol.51 , pp. 826-836
    • Zijlstra, E.E.1    El-Hassan, A.M.2    Ismael, A.3    Ghalib, H.W.4
  • 47
    • 77950461601 scopus 로고    scopus 로고
    • Origins and functional impact of copy number variation in the human genome
    • Conrad, D.F. et al. Origins and functional impact of copy number variation in the human genome. Nature 464, 704-712 (2010).
    • (2010) Nature , vol.464 , pp. 704-712
    • Conrad, D.F.1
  • 48
    • 70649103789 scopus 로고    scopus 로고
    • Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
    • Barrett, J.C. et al. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat. Genet. 41, 1330-1334 (2009).
    • (2009) Nat. Genet , vol.41 , pp. 1330-1334
    • Barrett, J.C.1
  • 49
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007).
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 559-575
    • Purcell, S.1
  • 50
    • 84971185409 scopus 로고
    • The correlation between relatives on the supposition of Mendelian inheritance
    • Fisher, R.A. The correlation between relatives on the supposition of Mendelian inheritance. Trans. R. Soc. Edinb. 52, 399-433 (1918).
    • (1918) Trans. R. Soc. Edinb , vol.52 , pp. 399-433
    • Fisher, R.A.1
  • 51
    • 0001421956 scopus 로고
    • Estimation of variance and covariance components
    • Henderson, C.R. Estimation of variance and covariance components. Biometrics 9, 226-252 (1953).
    • (1953) Biometrics , vol.9 , pp. 226-252
    • Henderson, C.R.1
  • 52
    • 0022649864 scopus 로고
    • The use of measured genotype information in the analysis of quantitative phenotypes in man.I. Models and analytical methods
    • Boerwinkle, E., Chakraborty, R. & Sing, C.F. The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods. Am. Hum. Genet. 50, 181-194 (1986).
    • (1986) Am. Hum. Genet , vol.50 , pp. 181-194
    • Boerwinkle, E.1    Chakraborty, R.2    Sing, C.F.3
  • 53
    • 34547628858 scopus 로고    scopus 로고
    • Family-based association tests for genomewide association scans
    • Chen, W.M. & Abecasis, G.R. Family-based association tests for genomewide association scans. Am. J. Hum. Genet. 81, 913-926 (2007).
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 913-926
    • Chen, W.M.1    Abecasis, G.R.2
  • 54
    • 31744440502 scopus 로고    scopus 로고
    • A unified mixed-model method for association mapping that accounts for multiple levels of relatedness
    • Yu, J. et al. A unified mixed-model method for association mapping that accounts for multiple levels of relatedness. Nat. Genet. 38, 203-208 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 203-208
    • Yu, J.1
  • 55
    • 35048838105 scopus 로고    scopus 로고
    • Genomewide rapid association using mixed model and regression: A fast and simple method for genomewide pedigree-based quantitative trait loci association analysis
    • Aulchenko, Y.S., de Koning, D.J. & Haley, C. Genomewide rapid association using mixed model and regression: a fast and simple method for genomewide pedigree-based quantitative trait loci association analysis. Genetics 177, 577-585 (2007).
    • (2007) Genetics , vol.177 , pp. 577-585
    • Aulchenko, Y.S.1    De Koning, D.J.2    Haley, C.3
  • 57
    • 84863003734 scopus 로고    scopus 로고
    • Genome-wide efficient mixed-model analysis for association studies
    • Zhou, X. & Stephens, M. Genome-wide efficient mixed-model analysis for association studies. Nat. Genet. 44, 821-824 (2012).
    • (2012) Nat. Genet , vol.44 , pp. 821-824
    • Zhou, X.1    Stephens, M.2
  • 58
    • 0034788171 scopus 로고    scopus 로고
    • Family-based association test method: Age of onset traits and covariates
    • Horvath, S., Wei, E., Xu, X., Palmer, L.J. & Baur, M. Family-based association test method: age of onset traits and covariates. Genet. Epidemiol. 21 (suppl. 1), S403-S408 (2001).
    • (2001) Genet. Epidemiol , vol.21 , Issue.SUPPL. 1
    • Horvath, S.1    Wei, E.2    Xu, X.3    Palmer, L.J.4    Baur, M.5
  • 59
    • 76049108917 scopus 로고    scopus 로고
    • ROADTRIPS case-control association testing with partially or completely unknown population and pedigree structure
    • Thornton, T. & McPeek, M.S. ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure. Am. J. Hum. Genet. 86, 172-184 (2010).
    • (2010) Am. J. Hum. Genet , vol.86 , pp. 172-184
    • Thornton, T.1    McPeek, M.S.2
  • 60
    • 0035130704 scopus 로고    scopus 로고
    • HLA-DRB1 DNA sequencing based typing: An approach suitable for high throughput typing including unrelated bone marrow registry donors
    • Sayer, D. et al. HLA-DRB1 DNA sequencing based typing: an approach suitable for high throughput typing including unrelated bone marrow registry donors. Tissue Antigens 57, 46-54 (2001).
    • (2001) Tissue Antigens , vol.57 , pp. 46-54
    • Sayer, D.1
  • 61
    • 13444269543 scopus 로고    scopus 로고
    • Haploview analysis and visualization of LD and haplotype maps
    • Barrett, J.C., Fry, B., Maller, J. & Daly, M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265 (2005).
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 62
    • 33644974019 scopus 로고    scopus 로고
    • A fast and flexible statistical model for large-scale population genotype data: Applications to inferring missing genotypes and haplotypic phase
    • Scheet, P. & Stephens, M. A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am. J. Hum. Genet. 78, 629-644 (2006).
    • (2006) Am. J. Hum. Genet , vol.78 , pp. 629-644
    • Scheet, P.1    Stephens, M.2
  • 63
    • 77949675926 scopus 로고    scopus 로고
    • Nomenclature for factors of the HLA system, 2010
    • Marsh, S.G. et al. Nomenclature for factors of the HLA system, 2010. Tissue Antigens 75, 291-455 (2010).
    • (2010) Tissue Antigens , vol.75 , pp. 291-455
    • Marsh, S.G.1
  • 64
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie, B.N., Donnelly, P. & Marchini, J. A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5, e1000529 (2009).
    • (2009) PLoS Genet , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 65
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens, M., Smith, N.J. & Donnelly, P. A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68, 978-989 (2001).
    • (2001) Am. J. Hum. Genet , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 66
    • 77953810149 scopus 로고    scopus 로고
    • A Bayesian method for detecting and characterizing allelic heterogeneity and boosting signals in genome-wide association studies
    • Su, Z., Cardin, N., Donnelly, P. & Marchini, J. A Bayesian method for detecting and characterizing allelic heterogeneity and boosting signals in genome-wide association studies. Stat. Sci. 24, 430-450 (2009).
    • (2009) Stat. Sci , vol.24 , pp. 430-450
    • Su, Z.1    Cardin, N.2    Donnelly, P.3    Marchini, J.4


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