Effect of stem cell-based therapy for ischemic stroke treatment: A meta-analysis

Clinical Neurology and Neurosurgery

Volumn 146, Issue , 2016, Pages 1-11

  Wang, Qian ^a   Duan, Feng ^b   Wang, Ming Xin ^a   Wang, Xiao Dong ^a   Liu, Peng ^b   Ma, Li Zhi ^a  

^a GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

^b NAVY GENERAL HOSPITAL   (China)

Author keywords

Cell transplantation; Clinical trial; Ischemic stroke; Meta analysis

Indexed keywords

ASSESSMENT OF HUMANS; BARTHEL INDEX; BRAIN ISCHEMIA; CONFIDENCE INTERVAL; DOSE RESPONSE; EUROPEAN STROKE SCALE; HUMAN; META ANALYSIS; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; RANKIN SCALE; REVIEW; RISK ASSESSMENT; RISK FACTOR; STEM CELL TRANSPLANTATION; THERAPY EFFECT; MESENCHYMAL STEM CELL TRANSPLANTATION; OUTCOME ASSESSMENT; PROCEDURES; STROKE;

BRAIN ISCHEMIA; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; OUTCOME ASSESSMENT (HEALTH CARE); STROKE;

EID: 84964812760     PISSN: 03038467     EISSN: 18726968     Source Type: Journal    
DOI: 10.1016/j.clineuro.2016.04.011     Document Type: Review

References (52)

1. E. Kokmen, J.P. Whisnant, W.M. O'Fallon, C.P. Chu, and C.M. Beard Dementia after ischemic stroke: a population-based study in Rochester, Minnesota (1960-1984) Neurology 46 1996 154 159 10.1212/WNL.46.1.154
2. S. Hägg, L.M. Thorn, J. Putaala, R. Liebkind, V. Harjutsalo, C.M. Forsblom, D. Gordin, T. Tatlisumak, P.H. Groop, and FinnDiane Study Group Incidence of stroke according to presence of diabetic nephropathy and severe diabetic retinopathy in patients with type 1 diabetes Diabetes Care 36 2013 4140 4146 10.2337/dc13-0669
3. P.M. Meyers, H.C. Schumacher, M.J. Alexander, C.P. Derdeyn, A.J. Furlan, R.T. Higashida, C.J. Moran, R.W. Tarr, D.V. Heck, J.A. Hirsch, M.E. Jensen, I. Linfante, C.G. McDougall, G.M. Nesbit, P.A. Rasmussen, T.A. Tomsick, L.R. Wechsler, J.R. Wilson, and O.O. Zaidat Performance and training standards for endovascular acute ischemic stroke treatment Neurology 79 2012 S234 S238 10.1212/WNL.0b013e318269595b
4. M. Muchada, M. Rubiera, D. Rodriguez-Luna, J. Pagola, A. Flores, J. Kallas, E. Sanjuan, P. Meler, J. Alvarez-Sabin, M. Ribo, and C.A. Molina Baseline National Institutes of Health stroke scale-adjusted time window for intravenous tissue-type plasminogen activator in acute ischemic stroke Stroke 45 2014 1059 1063 10.1161/STROKEAHA.113.004307
5. H.L. Parke, E. Epiphaniou, G. Pearce, S.J. Taylor, A. Sheikh, C.J. Griffiths, T. Greenhalgh, and H. Pinnock Self-management support interventions for stroke survivors: a systematic meta-review PLoS One 10 2015 e0131448 10.1371/journal.pone.0131448
6. L. Fjetland, S. Roy, K.D. Kurz, J.P. Larsen, and M.W. Kurz Endovascular acute stroke treatment performed by vascular interventional radiologists: is it safe and efficacious? Cardiovasc. Intervent. Radiol. 35 2012 1029 1035 10.1007/s00270-012-0438-5
7. D. Sacks, J.J. Connors 3rd, and C.M. Black Society of interventional radiology position statement on endovascular acute ischemic stroke interventions J. Vasc. Interv. Radiol. 24 2013 1263 1266 10.1016/j.jvir.2013.05.050
8. Y. Cheng, J. Zhang, L. Deng, N.R. Johnson, X. Yu, N. Zhang, T. Lou, Y. Zhang, X. Wei, Z. Chen, S. He, X. Li, and J. Xiao Intravenously delivered neural stem cells migrate into ischemic brain, differentiate and improve functional recovery after transient ischemic stroke in adult rats Int. J. Clin. Exp. Pathol. 8 2015 2928 2936
9. D.C. Yeh, T.M. Chan, H.J. Harn, T.W. Chiou, H.S. Chen, Z.S. Lin, and S.Z. Lin Adipose tissue-derived stem cells in neural regenerative medicine Cell Transplant. 24 2015 487 492 10.3727/096368915X686940
10. A. Popa-Wagner, A.M. Buga, T.R. Doeppner, and D.M. Hermann Stem cell therapies in preclinical models of stroke associated with aging Front. Cell. Neurosci. 8 347 2014 10.3389/fncel.2014.00347
11. M. Tatullo, M. Marrelli, and F. Paduano The regenerative medicine in oral and maxillofacial surgery: the most important innovations in the clinical application of mesenchymal stem cells Int. J. Med. Sci. 12 2015 72 77 10.7150/ijms.10706
12. F. Sánchez-Guijo, T. Caballero-Velázquez, O. López-Villar, A. Redondo, R. Parody, C. Martínez, E. Olavarría, E. Andreu, F. Prósper, M. Díez-Campelo, C. Regidor, E. Villaron, L. López-Corral, D. Caballero, M.C. Cañizo, and J.A. Pérez-Simon Sequential third-party mesenchymal stromal cell therapy for refractory acute graft-versus-host disease Biol. Blood Marrow Transplant. 20 2014 1580 1585 10.1016/j.bbmt.2014.06.015
13. Y. Lin, and W.J. Hogan Clinical application of mesenchymal stem cells in the treatment and prevention of graft-versus-host disease Adv. Hematol. 2011 2011 1 17 10.1155/2011/427863
14. J. Panés, I. Ordás, and E. Ricart Stem cell treatment for Crohn's disease Expert Rev. Clin. Immunol. 6 2010 597 605 10.1586/eci.10.27
15. D. Wang, and L. Sun Stem cell therapies for systemic lupus erythematosus: current progress and established evidence Expert Rev. Clin. Immunol. 11 2015 763 769 10.1586/1744666X.2015.1037741
16. T.J. Cashman, V. Gouon-Evans, and K.D. Costa Mesenchymal stem cells for cardiac therapy: practical challenges and potential mechanisms Stem Cell Rev. 9 2013 254 265 10.1007/s12015-012-9375-6
17. C.J. Centeno, and M.D. Freeman Percutaneous injection of autologous, culture-expanded mesenchymal stem cells into carpometacarpal hand joints: a case series with an untreated comparison group Wien Med. Wochenschr. 164 2014 83 87 10.1007/s10354-013-0222-4
18. A. Brent Reynolds, and STEPS Participants Stem cell therapies as an emerging paradigm in stroke participants, stem cell therapies as an emerging paradigm in stroke (STEPS): bridging basic and clinical science for cellular and neurogenic factor therapy in treating stroke Stroke 40 2009 510 515 10.1161/STROKEAHA.108.526863
19. S.I. Savitz, M. Chopp, R. Deans, T. Carmichael, D. Phinney, L. Wechsler, and STEPS Participants Stem cell therapy as an emerging paradigm for stroke (STEPS) II Stroke 42 2011 825 829 10.1161/STROKEAHA.110.601914
20. H. Jeong, H.W. Yim, Y.S. Cho, Y.I. Kim, S.N. Jeong, H.B. Kim, and I.H. Oh Efficacy and safety of stem cell therapies for patients with stroke: a systematic review and single arm meta-analysis Int. J. Stem Cells 7 2014 63 69 10.15283/ijsc.2014.7.2.63
21. G.G. Koning, J. Wetterslev, C.J. van Laarhoven, and F. Keus The totally extraperitoneal method versus Lichtenstein's technique for inguinal hernia repair: a systematic review with meta-analyses and trial sequential analyses of randomized clinical trials PLoS One 8 2013 e52599 10.1371/journal.pone.0052599
22. F. Keus, H.G. Gooszen, and C.J. van Laarhoven Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato-Biliary Group reviews Cochrane Database Syst. Rev. 1 2010 CD008318 10.1002/14651858
23. R.P. ten Broek, M.W. Stommel, C. Strik, C.J. van Laarhoven, F. Keus, and H. van Goor Benefits and harms of adhesion barriers for abdominal surgery: a systematic review and meta-analysis Lancet 383 2014 48 59 10.1016/S0140-6736(13)61687-6
24. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 J. Higgins, and S. Green 2011 The Cochrane Collaboration London
25. M. Davoli, L. Amato, N. Clark, M. Farrell, M. Hickman, S. Hill, N. Magrini, V. Poznyak, and H.J. Schünemann The role of Cochrane reviews in informing international guidelines: a case study of using the grading of recommendations, assessment, development and evaluation system to develop World Health Organization guidelines for the psychosocially assisted pharmacological treatment of opioid dependence Addiction 110 2015 891 898 10.1111/add.12788
26. S.P. Hozo, B. Djulbegovic, and I. Hozo Estimating the mean and variance from the median, range, and the size of a sample BMC Med. Res. Methodol. 5 2005 13 10.1186/1471-2288-5-13
27. Y. Rong, L. Chen, T. Zhu, Y. Song, M. Yu, Z. Shan, A. Sands, F.B. Hu, and L. Liu Egg consumption and risk of coronary heart disease and stroke: dose-response meta-analysis of prospective cohort studies BMJ 346 2013 e8539 10.1136/bmj.e8539
28. O.Y. Bang, J.S. Lee, P.H. Lee, and G. Lee Autologous mesenchymal stem cell transplantation in stroke patients Ann. Neurol. 57 2005 874 882 10.1002/ana.20501
29. J.S. Lee, J.M. Hong, G.J. Moon, P.H. Lee, Y.H. Ahn, O.Y. Bang, and Starting Collaborators A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke Stem Cells 28 2010 1099 1106 10.1002/stem.430
30. F. Moniche, A. Gonzalez, J.R. Gonzalez-Marcos, M. Carmona, P. Piñero, I. Espigado, D. Garcia-Solis, A. Cayuela, J. Montaner, C. Boada, A. Rosell, M.D. Jimenez, A. Mayol, and A. Gil-Peralta Intra-arterial bone marrow mononuclear cells in ischemic stroke: a pilot clinical trial Stroke 43 2012 2242 2244
31. K. Prasad, A. Sharma, A. Garg, S. Mohanty, S. Bhatnagar, S. Johri, K.K. Singh, V. Nair, R.S. Sarkar, S.P. Gorthi, K.M. Hassan, S. Prabhakar, N. Marwaha, N. Khandelwal, U.K. Misra, J. Kalita, S. Nityanand, and InveST Study Group Intravenous autologous bone marrow mononuclear stem cell therapy for ischemic stroke: a multicentric, randomized trial Stroke 45 2014 3618 3624 10.1161/STROKEAHA.114.007028
32. A. Bhasin, M.V. Srivastava, S.S. Kumaran, S. Mohanty, R. Bhatia, S. Bose, S. Gaikwad, A. Garg, and B. Airan Autologous mesenchymal stem cells in chronic stroke Cerebrovasc. Dis. Extra 1 2011 93 104 10.1159/000333381
33. A. Bhasin, M. Srivastava, R. Bhatia, S. Mohanty, S. Kumaran, and S. Bose Autologous intravenous mononuclear stem cell therapy in chronic ischemic stroke J. Stem Cells Regen. Med. 8 2012 181 189
34. D.C. Chen, S.Z. Lin, J.R. Fan, C.H. Lin, W. Lee, C.C. Lin, Y.J. Liu, C.H. Tsai, J.C. Chen, D.Y. Cho, C.C. Lee, and W.C. Shyu Intracerebral implantation of autologous peripheral blood stem cells in stroke patients: a randomized phase II study Cell Transplant. 23 2014 1599 1612 10.3727/096368914X678562
35. M.A. Berrevoets, R.S. van der Post, and N. Schaap A patient with pure red cell aplasia after allogenic stem-cell transplantation. Parvo B19 infection Neth. J. Med. 71 2013 370
36. J.E. Johansson, O. Nilsson, and P.O. Stotzer Colonoscopy and sigmoidoscopy are equally effective for the diagnosis of colonic acute graft-versus-host disease in patients with diarrhea after allogeneic stem cell transplantation: a prospective controlled trial Biol. Blood Marrow Transplant. 21 2015 2086 2090 10.1016/j.bbmt.2015.07.009
37. D. Wang, J. Li, Y. Zhang, M. Zhang, J. Chen, X. Li, X. Hu, S. Jiang, S. Shi, and L. Sun Umbilical cord mesenchymal stem cell transplantation in active and refractory systemic lupus erythematosus: a multicenter clinical study Arthritis Res. Ther. 16 2014 R79 10.1186/ar4520
38. C. Wang, Y. Fei, C. Xu, Y. Zhao, and Y. Pan Bone marrow mesenchymal stem cells ameliorate neurological deficits and blood-brain barrier dysfunction after intracerebral hemorrhage in spontaneously hypertensive rats Int. J. Clin. Exp. Pathol. 8 2015 4715 4724
39. L. Liu, M.A. Eckert, H. Riazifar, D.K. Kang, D. Agalliu, and W. Zhao From blood to the brain: can systemically transplanted mesenchymal stem cells cross the blood-brain barrier? Stem Cells Int. 2013 435093 10.1155/2013/435093
40. B. Vrtovec, G. Poglajen, M. Sever, L. Lezaic, D. Domanovic, P. Cernelc, F. Haddad, and G. Torre-Amione Effects of intracoronary stem cell transplantation in patients with dilated cardiomyopathy J. Card. Fail. 17 2011 272 281 10.1016/j.cardfail.2010.11.007
41. O. Ozkul-Wermester, E. Guegan-Massardier, A. Triquenot, A. Borden, G. Perot, and E. Gérardin Increased blood-brain barrier permeability on perfusion computed tomography predicts hemorrhagic transformation in acute ischemic stroke Eur. Neurol. 72 2014 45 53 10.1159/000358297
42. M. Giraud, T.H. Cho, N. Nighoghossian, D. Maucort-Boulch, G. Deiana, L. Østergaard, J.C. Baron, J. Fiehler, S. Pedraza, L. Derex, and Y. Berthezène Early blood brain barrier changes in acute ischemic stroke: a sequential MRI study J. Neuroimaging 25 2015 959 963 10.1111/jon.12225
43. N. Grigoriadis, A. Lourbopoulos, R. Lagoudaki, J.M. Frischer, E. Polyzoidou, O. Touloumi, C. Simeonidou, G. Deretzi, J. Kountouras, E. Spandou, K. Kotta, G. Karkavelas, N. Tascos, and H. Lassmann Variable behavior and complications of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis Exp. Neurol. 230 2011 78 89 10.1016/j.expneurol.2011.02.021
44. E.Y. Snyder The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brain Exp. Neurol. 230 2011 75 77 10.1016/j.expneurol.2011.03.012
45. A.J. Salgado, J.C. Sousa, B.M. Costa, A.O. Pires, A. Mateus-Pinheiro, F.G. Teixeira, L. Pinto, and N. Sousa Mesenchymal stem cells secretome as a modulator of the neurogenic niche: basic insights and therapeutic opportunities Front. Cell. Neurosci. 9 249 2015 10.3389/fncel.2015.00249
46. S.R. Baglio, K. Rooijers, D. Koppers-Lalic, F.J. Verweij, M. Pérez Lanzón, N. Zini, B. Naaijkens, F. Perut, H.W. Niessen, N. Baldini, and D.M. Pegtel Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species Stem Cell. Res. Ther. 6 127 2015 10.1186/s13287-015-0116-z
47. J.W. Hsu, J.R. Wingard, B.R. Logan, P. Chitphakdithai, G. Akpek, P. Anderlini, A.S. Artz, C. Bredeson, S. Goldstein, G. Hale, P. Hematti, S. Joshi, R.T. Kamble, H.M. Lazarus, P.V. O'Donnell, M.A. Pulsipher, B.N. Savani, R.M. Schears, B.E. Shaw, and D.L. Confer Race and ethnicity influences collection of granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells from unrelated donors, a Center for International Blood and Marrow Transplant Research analysis Biol. Blood Marrow Transplant. 21 2015 165 171 10.1016/j.bbmt.2014.10.007
48. M. Bhatia, and S. Sheth Hematopoietic stem cell transplantation in sickle cell disease: patient selection and special considerations J. Blood Med. 6 2015 229 238 10.2147/JBM.S60515
49. D. Kondziolka, G.K. Steinberg, L. Wechsler, C.C. Meltzer, E. Elder, J. Gebel, S. Decesare, T. Jovin, R. Zafonte, J. Lebowitz, J.C. Flickinger, D. Tong, M.P. Marks, C. Jamieson, D. Luu, T. Bell-Stephens, and J. Teraoka Neurotransplantation for patients with subcortical motor stroke: a phase 2 randomized trial J. Neurosurg. 103 2005 38 45 10.3171/jns.2005.103.1.0038
50. D.C. Hess, C.A. Sila, A.J. Furlan, L.R. Wechsler, J.A. Switzer, and R.W. Mays A double-blind placebo-controlled clinical evaluation of MultiStem for the treatment of ischemic stroke Int. J. Stroke 9 2014 381 386 10.1111/ijs.12065
51. S.J. Kim, G.J. Moon, W.H. Chang, Y.H. Kim, O.Y. Bang, and STARTING-2 (STem cell Application Researches and Trials In NeuroloGy-2) collaborators Intravenous transplantation of mesenchymal stem cells preconditioned with early phase stroke serum: current evidence and study protocol for a randomized trial Trials 14 2013 317 10.1186/1745-6215-14-317
52. E. Díez-Tejedor, M. Gutiérrez-Fernández, P. Martínez-Sánchez, B. Rodríguez-Frutos, G. Ruiz-Ares, M.L. Lara, and B.F. Gimeno Reparative therapy for acute ischemic stroke with allogeneic mesenchymal stem cells from adipose tissue: a safety assessment: a phase II randomized, double-blind, placebo-controlled, single-center, pilot clinical trial J. Stroke Cerebrovasc. Dis. 23 2014 2694 2700 10.1016/j.jstrokecerebrovasdis.2014.06.011