Early Blood Brain Barrier Changes in Acute Ischemic Stroke: A Sequential MRI Study

Journal of Neuroimaging

Volumn 25, Issue 6, 2015, Pages 959-963

  Giraud, Marc ^a   Cho, Tae Hee ^a   Nighoghossian, Norbert ^a   Maucort Boulch, Delphine ^a,b,g   Deiana, Gianluca ^a   Østergaard, Leif ^c   Baron, Jean Claude ^d,h   Fiehler, Jens ^e   Pedraza, Salvador ^f   Derex, Laurent ^a   Berthezène, Yves ^a  

^a UNIVERSITÉ LYON 1   (France)

^b HOSPICES CIVILS DE LYON   (France)

^c AARHUS UNIVERSITY   (Denmark)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^f HOSPITAL JOSEP TRUETA   (Spain)

^g LABORATOIRE DE BIOMÉTRIE ET BIOLOGIE EVOLUTIVE   (France)

^h CENTRE HOSPITALIER SAINTE ANNE   (France)

Author keywords

Blood brain barrier; Ischemic stroke; MRI

Indexed keywords

GADOLINIUM;

ADULT; AGED; ARTICLE; BLOOD BRAIN BARRIER; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN ISCHEMIA; CLINICAL ARTICLE; CONTRAST ENHANCEMENT; CONTRAST MEDIUM EXTRAVASATION; CONTROLLED STUDY; FEMALE; HEMODYNAMIC PARAMETERS; HUMAN; INSULA; LEPTOMENINX; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MEMBRANE DAMAGE; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; PERFUSION WEIGHTED IMAGING; STROKE PATIENT; CEREBROVASCULAR ACCIDENT; DIAGNOSTIC IMAGING; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; TIME FACTOR;

AGED; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; STROKE; TIME FACTORS;

EID: 84944514943     PISSN: 10512284     EISSN: 15526569     Source Type: Journal    
DOI: 10.1111/jon.12225     Document Type: Article

References (27)

1. Khatri R, McKinney AM, Swenson B, et al. Blood-brain barrier, reperfusion injury, and hemorrhagic transformation in acute ischemic stroke. Neurology 2012;79:S52-7.
2. Knight A, Barker B, Fagan C, et al. Prediction of impending hemorrhagic transformation in ischemic stroke using magnetic resonance imaging in rats editorial comment. Stroke 1998;29:144-51.
3. Latour LL, Kang DW, Ezzeddine MA, et al. Early blood-brain barrier disruption in human focal brain ischemia. Ann Neurol 2004;56:468-77.
4. Warach S, Latour LL. Evidence of reperfusion injury, exacerbated by thrombolytic therapy, in human focal brain ischemia using a novel imaging marker of early blood-brain barrier disruption. Stroke 2004;35:2659-61.
5. Hjort N, Wu O, Ashkanian M, et al. MRI detection of early blood-brain barrier disruption: parenchymal enhancement predicts focal hemorrhagic transformation after thrombolysis. Stroke 2008;39:1025-8.
6. Kastrup A, Gröschel K, Ringer TM, et al. Early disruption of the blood-brain barrier after thrombolytic therapy predicts hemorrhage in patients with acute stroke. Stroke 2008;39:2385-7.
7. Bang OY, Saver JL, Alger JR, et al. UCLA MRI Permeability Investigators. Patterns and predictors of blood-brain barrier permeability derangements in acute ischemic stroke. Stroke 2009;40:454-61.
8. Leigh R, Jen SS, Hillis AE, et al. Pretreatment blood-brain barrier damage and post-treatment intracranial hemorrhage in patients receiving intravenous tissue-type plasminogen activator. Stroke 2014;45(7):2030-5.
9. Thomalla G, Cheng B, Ebinger M, et al. STIR and VISTA Imaging Investigators. DWI-FLAIR mismatch for the identification of patients with acute ischaemic stroke within 4·5 h of symptom onset (PRE-FLAIR): a multicentre observational study. Lancet Neurol 2011;10:978-86.
10. Thomalla G, Fiebach JB, Ostergaard L, et al. A multicenter, randomized, double-blind, placebo-controlled trial to test efficacy and safety of magnetic resonance imaging-based thrombolysis in wake-up stroke (WAKE-UP). Int J Stroke 2014;9(6):829-36.
11. Petkova M, Rodrigo S, Lamy C, et al. MR imaging helps predict time from symptom onset in patients with acute stroke: implications for patients with unknown onset time. Radiology 2010;257:782-92.
12. Higashida RT, Furlan AJ, Roberts H, et al. Technology Assessment Committee of the Society of Interventional Radiology. Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke. Stroke 2003;34:e109-37.
13. Hacke W, Kaste M, Fieschi C, et al. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European-Australasian Acute Stroke Study Investigators. Lancet 1998;352:1245-51.
14. Ewing JR, Knight RA, Nagaraja TN, et al. Patlak plots of Gd-DTPA MRI data yield blood-brain transfer constants concordant with those of 14C-sucrose in areas of blood-brain opening. Magn Reson Med 2003;50:283-92.
15. Kim EY, Na DG, Kim SS, et al. Prediction of hemorrhagic transformation in acute ischemic stroke: role of diffusion-weighted imaging and early parenchymal enhancement. Am J Neuroradiol 2005;26:1050-5.
16. Liu HS, Chung HW, Chou MC, et al. Effects of microvascular permeability changes on contrast-enhanced T1 and pharmacokinetic MR imagings after ischemia. Stroke 2013;44:1872-7.
17. Scalzo F, Alger JR, Hu X, et al. on behalf of the STIR/VISTA Imaging Investigators. Multi-center prediction of hemorrhagic transformation in acute ischemic stroke using permeability imaging features. Magn Reson Imaging 2013;31(6):961-9.
18. Dankbaar JW, Hom J, Schneider T, et al. Dynamic perfusion CT assessment of the blood-brain barrier permeability: first pass versus delayed acquisition. Am J Neuroradiol 2008;29:1671-6.
19. Dankbaar JW, Hom J, Schneider T, et al. Dynamic perfusion-CT assessment of early changes in blood brain barrier permeability of acute ischaemic stroke patients. J Neuroradiol 2011;38:161-6.
20. Desilles JP, Rouchaud A, Labreuche J, et al. Blood-brain barrier disruption is associated with increased mortality after endovascular therapy. Neurology 2013;80:844-51.
21. Nguyen GT, Coulthard A, Wong A, et al. Measurement of blood-brain barrier permeability in acute ischemic stroke using standard first-pass perfusion CT data. Neuroimage Clin 2013;2:658-62.
22. Ozkul-Wermester O, Guegan-Massardier E, Triquenot A, et al. Increased blood-brain barrier permeability on perfusion computed tomography predicts hemorrhagic transformation in acute ischemic stroke. Eur Neurol 2014;72:45-53.
23. Heye AK, Culling RD, Valdés Hernández MD, et al. Assessment of blood-brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review. Neuroimage Clin 2014;6:262-74.
24. Castellanos M, Leira R, Serena J, et al. Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute Ischemic stroke * editorial comment. Stroke 2003;34:40-6.
25. Campbell BC, Christensen S, Parsons MW, et al. EPITHET and DEFUSE Investigators. Advanced imaging improves prediction of hemorrhage after stroke thrombolysis. Ann Neurol 2013;73:510-9.
26. Ostwaldt AC, Rozanski M, Schmidt WU, et al. Early time course of FLAIR signal intensity differs between acute ischemic stroke patients with and without hyperintense acute reperfusion marker. Cerebrovasc Dis 2014;37:141-6.
27. Jha R, Battey TW, Pham L, et al. Fluid-attenuated inversion recovery hyperintensity correlates with matrix metalloproteinase-9 level and hemorrhagic transformation in acute ischemic stroke. Stroke 2014;4:1040-5.