메뉴 건너뛰기




Volumn 65, Issue 1, 2016, Pages 48-56

HBcrAg predicts hepatocellular carcinoma development: An analysis using time-dependent receiver operating characteristics

Author keywords

Hepatitis B; Hepatitis B virus core related antigen; Hepatocellular carcinoma; Time dependent receiver operating characteristic

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALPHA FETOPROTEIN; ASPARTATE AMINOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; HEPATITIS B ANTIGEN; HEPATITIS B CORE ANTIGEN; HEPATITIS B CORE RELATED ANTIGEN; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; INTERFERON; UNCLASSIFIED DRUG; VIRUS DNA;

EID: 84964812004     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2016.03.013     Document Type: Article
Times cited : (126)

References (46)
  • 2
    • 1642410856 scopus 로고    scopus 로고
    • Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • D. Lavanchy Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures J Viral Hepat 11 2004 97 107
    • (2004) J Viral Hepat , vol.11 , pp. 97-107
    • Lavanchy, D.1
  • 3
    • 0019451351 scopus 로고
    • Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22,707 men in Taiwan
    • R.P. Beasley, L.Y. Hwang, C.C. Lin, and C.S. Chien Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22,707 men in Taiwan Lancet 2 1981 1129 1133
    • (1981) Lancet , vol.2 , pp. 1129-1133
    • Beasley, R.P.1    Hwang, L.Y.2    Lin, C.C.3    Chien, C.S.4
  • 4
    • 0017796073 scopus 로고
    • Hepatocellular carcinoma and the hepatitis B virus: Evidence for a causal association
    • W. Szmuness Hepatocellular carcinoma and the hepatitis B virus: evidence for a causal association Prog Med Virol 24 1978 40 69
    • (1978) Prog Med Virol , vol.24 , pp. 40-69
    • Szmuness, W.1
  • 5
    • 0023475719 scopus 로고
    • Epidemiology of hepatocellular carcinoma
    • V.K. Rustgi Epidemiology of hepatocellular carcinoma Gastroenterol Clin North Am 16 1987 545 551
    • (1987) Gastroenterol Clin North Am , vol.16 , pp. 545-551
    • Rustgi, V.K.1
  • 7
    • 0030785082 scopus 로고    scopus 로고
    • Epidemiological characteristics and risk factors of hepatocellular carcinoma
    • C.J. Chen, M.W. Yu, and Y.F. Liaw Epidemiological characteristics and risk factors of hepatocellular carcinoma J Gastroenterol Hepatol 12 1997 S294 S308
    • (1997) J Gastroenterol Hepatol , vol.12 , pp. S294-S308
    • Chen, C.J.1    Yu, M.W.2    Liaw, Y.F.3
  • 8
    • 0036614299 scopus 로고    scopus 로고
    • Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B
    • Y.S. Hsu, R.N. Chien, C.T. Yeh, I.S. Sheen, H.Y. Chiou, C.M. Chu, and et al. Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B Hepatology 35 2002 1522 1527
    • (2002) Hepatology , vol.35 , pp. 1522-1527
    • Hsu, Y.S.1    Chien, R.N.2    Yeh, C.T.3    Sheen, I.S.4    Chiou, H.Y.5    Chu, C.M.6
  • 9
    • 84984535720 scopus 로고    scopus 로고
    • Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B
    • J.H. Kao, P.J. Chen, M.Y. Lai, and D.S. Chen Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B Gastroenterology 118 2000 554 559
    • (2000) Gastroenterology , vol.118 , pp. 554-559
    • Kao, J.H.1    Chen, P.J.2    Lai, M.Y.3    Chen, D.S.4
  • 10
    • 56949094767 scopus 로고    scopus 로고
    • Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B
    • M.F. Yuen, Y. Tanaka, D.Y. Fong, J. Fung, D.K. Wong, J.C. Yuen, and et al. Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B J Hepatol 50 2009 80 88
    • (2009) J Hepatol , vol.50 , pp. 80-88
    • Yuen, M.F.1    Tanaka, Y.2    Fong, D.Y.3    Fung, J.4    Wong, D.K.5    Yuen, J.C.6
  • 11
    • 0034808384 scopus 로고    scopus 로고
    • Determination of hepatitis B virus genotype G by polymerase chain reaction with hemi-nested primers
    • H. Kato, E. Orito, F. Sugauchi, R. Ueda, R.G. Gish, S. Usuda, and et al. Determination of hepatitis B virus genotype G by polymerase chain reaction with hemi-nested primers J Virol Methods 98 2001 153 159
    • (2001) J Virol Methods , vol.98 , pp. 153-159
    • Kato, H.1    Orito, E.2    Sugauchi, F.3    Ueda, R.4    Gish, R.G.5    Usuda, S.6
  • 12
    • 58149250976 scopus 로고    scopus 로고
    • Correlation between serum hepatitis B virus core-related antigen and intrahepatic covalently closed circular DNA in chronic hepatitis B patients
    • F. Suzuki, H. Miyakoshi, M. Kobayashi, and H. Kumada Correlation between serum hepatitis B virus core-related antigen and intrahepatic covalently closed circular DNA in chronic hepatitis B patients J Med Virol 81 2009 27 33
    • (2009) J Med Virol , vol.81 , pp. 27-33
    • Suzuki, F.1    Miyakoshi, H.2    Kobayashi, M.3    Kumada, H.4
  • 13
    • 34347327086 scopus 로고    scopus 로고
    • Low serum level of hepatitis B core-related antigen indicates unlikely reactivation of hepatitis after cessation of lamivudine therapy
    • A. Matsumoto, E. Tanaka, M. Minami, T. Okanoue, H. Yatsuhashi, S. Nagaoka, and et al. Low serum level of hepatitis B core-related antigen indicates unlikely reactivation of hepatitis after cessation of lamivudine therapy Hepatol Res 37 2007 661 666
    • (2007) Hepatol Res , vol.37 , pp. 661-666
    • Matsumoto, A.1    Tanaka, E.2    Minami, M.3    Okanoue, T.4    Yatsuhashi, H.5    Nagaoka, S.6
  • 14
    • 79951651043 scopus 로고    scopus 로고
    • HBcrAg is a predictor of post-treatment recurrence of hepatocellular carcinoma during antiviral therapy
    • T. Hosaka, F. Suzuki, M. Kobayashi, M. Hirakawa, Y. Kawamura, H. Yatsuji, and et al. HBcrAg is a predictor of post-treatment recurrence of hepatocellular carcinoma during antiviral therapy Liver Int 30 2010 1461 1470
    • (2010) Liver Int , vol.30 , pp. 1461-1470
    • Hosaka, T.1    Suzuki, F.2    Kobayashi, M.3    Hirakawa, M.4    Kawamura, Y.5    Yatsuji, H.6
  • 15
    • 70349240414 scopus 로고    scopus 로고
    • Chronic hepatitis B: Update 2009
    • A.S. Lok, and B.J. McMahon Chronic hepatitis B: update 2009 Hepatology 50 2009 661 662
    • (2009) Hepatology , vol.50 , pp. 661-662
    • Lok, A.S.1    McMahon, B.J.2
  • 16
    • 84862664371 scopus 로고    scopus 로고
    • EASL clinical practice guidelines: Management of chronic hepatitis B virus infection
    • European Association for the Study of the Liver EASL clinical practice guidelines: management of chronic hepatitis B virus infection J Hepatol 57 2012 167 185
    • (2012) J Hepatol , vol.57 , pp. 167-185
  • 17
    • 84865376141 scopus 로고    scopus 로고
    • Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2012 update
    • Yun-Fan Liaw, Jia-Horng Kao, Teerha Piratvisuth, Henry Lik Yuen Chan, Rong-Nan Chien, Chun-Jen Liu, and et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update Hepatol Int 6 2012 531 561
    • (2012) Hepatol Int , vol.6 , pp. 531-561
    • Liaw, Y.-F.1    Kao, J.-H.2    Piratvisuth, T.3    Chan, H.L.Y.4    Chien, R.-N.5    Liu, C.-J.6
  • 18
    • 84879607066 scopus 로고    scopus 로고
    • Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection
    • T. Hosaka, F. Suzuki, M. Kobayashi, Y. Seko, Y. Kawamura, H. Sezaki, and et al. Long-term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection Hepatology 58 2013 98 107
    • (2013) Hepatology , vol.58 , pp. 98-107
    • Hosaka, T.1    Suzuki, F.2    Kobayashi, M.3    Seko, Y.4    Kawamura, Y.5    Sezaki, H.6
  • 19
    • 84874111839 scopus 로고    scopus 로고
    • Effect of nucleos(t)ide analogue therapy on hepatocarcinogenesis in chronic hepatitis B patients: A propensity score analysis
    • T. Kumada, H. Toyoda, T. Tada, S. Kiriyama, M. Tanikawa, Y. Hisanaga, and et al. Effect of nucleos(t)ide analogue therapy on hepatocarcinogenesis in chronic hepatitis B patients: a propensity score analysis J Hepatol 58 2013 427 433
    • (2013) J Hepatol , vol.58 , pp. 427-433
    • Kumada, T.1    Toyoda, H.2    Tada, T.3    Kiriyama, S.4    Tanikawa, M.5    Hisanaga, Y.6
  • 20
    • 15044357936 scopus 로고    scopus 로고
    • Survival model predictive accuracy and ROC curves
    • P.J. Heagerty, and Y. Zheng Survival model predictive accuracy and ROC curves Biometrics 61 2005 92 105
    • (2005) Biometrics , vol.61 , pp. 92-105
    • Heagerty, P.J.1    Zheng, Y.2
  • 21
    • 84880949810 scopus 로고    scopus 로고
    • Heavy alcohol consumption increases the incidence of hepatocellular carcinoma in hepatitis B virus-related cirrhosis
    • C.W. Lin, C.C. Lin, L.R. Mo, C.Y. Chang, D.S. Perng, C.C. Hsu, and et al. Heavy alcohol consumption increases the incidence of hepatocellular carcinoma in hepatitis B virus-related cirrhosis J Hepatol 58 2013 730 735
    • (2013) J Hepatol , vol.58 , pp. 730-735
    • Lin, C.W.1    Lin, C.C.2    Mo, L.R.3    Chang, C.Y.4    Perng, D.S.5    Hsu, C.C.6
  • 22
    • 84940322120 scopus 로고    scopus 로고
    • The diagnostic value of the FIB-4 index for staging hepatitis B-related fibrosis: A meta-analysis
    • Y. Li, Y. Chen, and Y. Zhao The diagnostic value of the FIB-4 index for staging hepatitis B-related fibrosis: a meta-analysis PLoS One 9 2014 e105728
    • (2014) PLoS One , vol.9
    • Li, Y.1    Chen, Y.2    Zhao, Y.3
  • 23
    • 77950605836 scopus 로고    scopus 로고
    • Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients
    • B.K. Kim, Y. Kim do, J.Y. Park, S.H. Ahn, C.Y. Chon, J.K. Kim, and et al. Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients Liver Int 30 2010 546 553
    • (2010) Liver Int , vol.30 , pp. 546-553
    • Kim, B.K.1    Kim do, Y.2    Park, J.Y.3    Ahn, S.H.4    Chon, C.Y.5    Kim, J.K.6
  • 25
    • 28844480321 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma
    • J. Bruix, and M. Sherman Management of hepatocellular carcinoma Hepatology 42 2005 1208 1236
    • (2005) Hepatology , vol.42 , pp. 1208-1236
    • Bruix, J.1    Sherman, M.2
  • 26
    • 79952231921 scopus 로고    scopus 로고
    • Management ofhepatocellular carcinoma: An update
    • J. Bruix, and M. Sherman Management ofhepatocellular carcinoma: an update Hepatology 53 2011 1020 1022
    • (2011) Hepatology , vol.53 , pp. 1020-1022
    • Bruix, J.1    Sherman, M.2
  • 27
    • 0038290377 scopus 로고    scopus 로고
    • New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA
    • T. Kimura, A. Rokuhara, A. Matsumoto, S. Yagi, E. Tanaka, K. Kiyosawa, and et al. New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA J Clin Microbiol 41 2003 1901 1906
    • (2003) J Clin Microbiol , vol.41 , pp. 1901-1906
    • Kimura, T.1    Rokuhara, A.2    Matsumoto, A.3    Yagi, S.4    Tanaka, E.5    Kiyosawa, K.6
  • 28
    • 37249092014 scopus 로고    scopus 로고
    • Hepatitis B virus core-related antigens as markers for monitoring chronic hepatitis B infection
    • D.K. Wong, Y. Tanaka, C.L. Lai, M. Mizokami, J. Fung, and M.F. Yuen Hepatitis B virus core-related antigens as markers for monitoring chronic hepatitis B infection J Clin Microbiol 45 2007 3942 3947
    • (2007) J Clin Microbiol , vol.45 , pp. 3942-3947
    • Wong, D.K.1    Tanaka, Y.2    Lai, C.L.3    Mizokami, M.4    Fung, J.5    Yuen, M.F.6
  • 29
    • 84984584170 scopus 로고    scopus 로고
    • Evolution of precore/core promoter mutations in hepatitis B carriers with hepatitis B e antigen seroreversion
    • C.J. Liu, P.J. Chen, M.Y. Lai, J.H. Kao, and D.S. Chen Evolution of precore/core promoter mutations in hepatitis B carriers with hepatitis B e antigen seroreversion J Med Virol 74 2004 237 245
    • (2004) J Med Virol , vol.74 , pp. 237-245
    • Liu, C.J.1    Chen, P.J.2    Lai, M.Y.3    Kao, J.H.4    Chen, D.S.5
  • 30
    • 84983726628 scopus 로고    scopus 로고
    • Hepatitis B genotypes and the response to interferon therapy
    • J.H. Kao, N.H. Wu, P.J. Chen, M.Y. Lai, and D.S. Chen Hepatitis B genotypes and the response to interferon therapy J Hepatol 33 2000 998 1002
    • (2000) J Hepatol , vol.33 , pp. 998-1002
    • Kao, J.H.1    Wu, N.H.2    Chen, P.J.3    Lai, M.Y.4    Chen, D.S.5
  • 31
    • 84983726112 scopus 로고    scopus 로고
    • High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load
    • T.C. Tseng, C.J. Liu, H.C. Yang, T.H. Su, C.C. Wang, C.L. Chen, and et al. High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load Gastroenterology 142 2012 1140 1149
    • (2012) Gastroenterology , vol.142 , pp. 1140-1149
    • Tseng, T.C.1    Liu, C.J.2    Yang, H.C.3    Su, T.H.4    Wang, C.C.5    Chen, C.L.6
  • 32
    • 29944436855 scopus 로고    scopus 로고
    • REVEAL-HBV Study Group. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
    • C.J. Chen, H.I. Yang, J. Su, C.L. Jen, S.L. You, S.N. Lu, and et al. REVEAL-HBV Study Group. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level JAMA 295 2006 65 73
    • (2006) JAMA , vol.295 , pp. 65-73
    • Chen, C.J.1    Yang, H.I.2    Su, J.3    Jen, C.L.4    You, S.L.5    Lu, S.N.6
  • 33
  • 34
    • 84984578046 scopus 로고    scopus 로고
    • Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads
    • T.C. Tseng, C.J. Liu, H.C. Yang, T.H. Su, C.C. Wang, C.L. Chen, and et al. Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads Hepatology 57 2013 441 450
    • (2013) Hepatology , vol.57 , pp. 441-450
    • Tseng, T.C.1    Liu, C.J.2    Yang, H.C.3    Su, T.H.4    Wang, C.C.5    Chen, C.L.6
  • 35
    • 78651510442 scopus 로고    scopus 로고
    • A population-based cohort study for the risk factors of HCC among hepatitis B virus mono-infected subjects in Japan
    • A. Kusakabe, Y. Tanaka, M. Inoue, F. Kurbanov, K. Tatematsu, S. Nojiri, and et al. A population-based cohort study for the risk factors of HCC among hepatitis B virus mono-infected subjects in Japan J Gastroenterol 46 2011 117 124
    • (2011) J Gastroenterol , vol.46 , pp. 117-124
    • Kusakabe, A.1    Tanaka, Y.2    Inoue, M.3    Kurbanov, F.4    Tatematsu, K.5    Nojiri, S.6
  • 36
    • 84993219620 scopus 로고    scopus 로고
    • Clinical outcomes and predictors for relapse after cessation of oral antiviral treatment in chronic hepatitis B patients
    • [Epub ahead of print]
    • K.S. Jung, J.Y. Park, Y.E. Chon, H.S. Kim, W. Kang, B.K. Kim, and et al. Clinical outcomes and predictors for relapse after cessation of oral antiviral treatment in chronic hepatitis B patients J Gastroenterol 2015 [Epub ahead of print]
    • (2015) J Gastroenterol
    • Jung, K.S.1    Park, J.Y.2    Chon, Y.E.3    Kim, H.S.4    Kang, W.5    Kim, B.K.6
  • 37
    • 84875215709 scopus 로고    scopus 로고
    • Investigation of the freely available easy-to-use software 'EZR' for medical statistics
    • Y. Kanda Investigation of the freely available easy-to-use software 'EZR' for medical statistics Bone Marrow Transplant 48 2013 452 458
    • (2013) Bone Marrow Transplant , vol.48 , pp. 452-458
    • Kanda, Y.1
  • 38
    • 84891907570 scopus 로고    scopus 로고
    • Drafting Committee for Hepatitis Management Guidelines and the Japan Society of Hepatology. JSH guidelines for the management of hepatitis B virus infection
    • Drafting Committee for Hepatitis Management Guidelines and the Japan Society of Hepatology. JSH guidelines for the management of hepatitis B virus infection Hepatol Res 44 2014 1 58
    • (2014) Hepatol Res , vol.44 , pp. 1-58
  • 39
    • 0036159549 scopus 로고    scopus 로고
    • Sensitive enzyme immunoassay for hepatitis B virus core-related antigens and their correlation to virus load
    • T. Kimura, A. Rokuhara, Y. Sakamoto, S. Yagi, E. Tanaka, K. Kiyosawa, and et al. Sensitive enzyme immunoassay for hepatitis B virus core-related antigens and their correlation to virus load J Clin Microbiol 40 2002 439 445
    • (2002) J Clin Microbiol , vol.40 , pp. 439-445
    • Kimura, T.1    Rokuhara, A.2    Sakamoto, Y.3    Yagi, S.4    Tanaka, E.5    Kiyosawa, K.6
  • 40
    • 84975031165 scopus 로고    scopus 로고
    • HBcrAg during nucleos(t)ide analog therapy are related to intra-hepatic HBV replication and development of hepatocellular carcinoma
    • [Epub ahead of print]
    • M. Honda, T. Shirasaki, T. Terashima, K. Kawaguchi, M. Nakamura, N. Oishi, and et al. HBcrAg during nucleos(t)ide analog therapy are related to intra-hepatic HBV replication and development of hepatocellular carcinoma J Infect Dis 2015 [Epub ahead of print]
    • (2015) J Infect Dis
    • Honda, M.1    Shirasaki, T.2    Terashima, T.3    Kawaguchi, K.4    Nakamura, M.5    Oishi, N.6
  • 41
    • 51049117284 scopus 로고    scopus 로고
    • Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma
    • H.I. Yang, S.H. Yeh, P.J. Chen, U.H. Iloeje, C.L. Jen, J. Su, and et al. Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma J Natl Cancer Inst 100 2008 1134 1143
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1134-1143
    • Yang, H.I.1    Yeh, S.H.2    Chen, P.J.3    Iloeje, U.H.4    Jen, C.L.5    Su, J.6
  • 42
    • 84984559412 scopus 로고    scopus 로고
    • Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers
    • C.J. Liu, B.F. Chen, P.J. Chen, M.Y. Lai, W.L. Huang, J.H. Kao, and et al. Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers J Infect Dis 193 2006 1258 1265
    • (2006) J Infect Dis , vol.193 , pp. 1258-1265
    • Liu, C.J.1    Chen, B.F.2    Chen, P.J.3    Lai, M.Y.4    Huang, W.L.5    Kao, J.H.6
  • 43
    • 38349105023 scopus 로고    scopus 로고
    • Temporal relationship between hepatitis B virus enhancer II/basal core promoter sequence variation and risk of hepatocellular carcinoma
    • Y.C. Chou, M.W. Yu, C.F. Wu, S.Y. Yang, C.L. Lin, C.J. Liu, and et al. Temporal relationship between hepatitis B virus enhancer II/basal core promoter sequence variation and risk of hepatocellular carcinoma Gut 57 2008 91 97
    • (2008) Gut , vol.57 , pp. 91-97
    • Chou, Y.C.1    Yu, M.W.2    Wu, C.F.3    Yang, S.Y.4    Lin, C.L.5    Liu, C.J.6
  • 44
    • 84920940527 scopus 로고    scopus 로고
    • Higher proportion of viral basal core promoter mutant increases the risk of liver cirrhosis in hepatitis B carriers
    • T.C. Tseng, C.J. Liu, H.C. Yang, C.L. Chen, W.T. Yang, and C.S. Tsai Higher proportion of viral basal core promoter mutant increases the risk of liver cirrhosis in hepatitis B carriers Gut 64 2015 292 302
    • (2015) Gut , vol.64 , pp. 292-302
    • Tseng, T.C.1    Liu, C.J.2    Yang, H.C.3    Chen, C.L.4    Yang, W.T.5    Tsai, C.S.6
  • 45
    • 0029165057 scopus 로고
    • Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver
    • M.R. Teli, C.P. Day, A.D. Burt, M.K. Bennett, and O.F. James Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver Lancet 346 1995 987 990
    • (1995) Lancet , vol.346 , pp. 987-990
    • Teli, M.R.1    Day, C.P.2    Burt, A.D.3    Bennett, M.K.4    James, O.F.5
  • 46
    • 6844258880 scopus 로고    scopus 로고
    • Drinking habits as cofactors of risk for alcohol induced liver damage. the Dionysos Study Group
    • S. Bellentani, G. Saccoccio, G. Costa, C. Tiribelli, F. Manenti, M. Sodde, and et al. Drinking habits as cofactors of risk for alcohol induced liver damage. The Dionysos Study Group Gut 41 1997 845 850
    • (1997) Gut , vol.41 , pp. 845-850
    • Bellentani, S.1    Saccoccio, G.2    Costa, G.3    Tiribelli, C.4    Manenti, F.5    Sodde, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.