The diagnostic value of the FIB-4 index for staging hepatitis B-related fibrosis: A meta-analysis

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Li, Yuanyuan ^a   Chen, Yu ^a   Zhao, Ying ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIVARIATE ANALYSIS; COCHRANE LIBRARY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DISEASE CLASSIFICATION; EMBASE; FIB 4 INDEX; HEPATITIS B; HUMAN; INFORMATION RETRIEVAL; INTERMETHOD COMPARISON; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; MEDLINE; META ANALYSIS (TOPIC); NON INVASIVE MEASUREMENT; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; BLOOD; LIVER; META ANALYSIS; PATHOLOGY;

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; HEPATITIS B; HUMANS; LIVER; LIVER CIRRHOSIS; SENSITIVITY AND SPECIFICITY;

EID: 84940322120     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0105728     Document Type: Article

References (74)

1. Liaw YF, Sung JJ, Chow WC, Farrell G, Lee CZ, et al. (2004) Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med 351: 1521-1531.
2. Lok AS, McMahon BJ (2007) Chronic hepatitis B. Hepatology 45: 507-539. (Pubitemid 46374607)
3. (2012) EASL clinical practice guidelines: Management of chronic hepatitis B virus infection. J Hepatol 57: 167-185.
4. de Franchis R (2008) Non-invasive (and minimally invasive) diagnosis of oesophageal varices. J Hepatol 49: 520-527.
5. Bravo AA, Sheth SG, Chopra S (2001) Liver biopsy. N Engl J Med 344: 495-500. (Pubitemid 32164902)
6. Bedossa P, Dargere D, Paradis V (2003) Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology 38: 1449-1457. (Pubitemid 37466971)
7. Friedman LS (2004) Controversies in liver biopsy: who, where, when, how, why? Curr Gastroenterol Rep 6: 30-36.
8. Bedossa P, Poynard T (1996) An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 24: 289-293. (Pubitemid 26260021)
9. Ma J, Jiang Y, Gong G (2013) Evaluation of seven noninvasive models in staging liver fibrosis in patients with chronic hepatitis B virus infection. Eur J Gastroenterol Hepatol 25: 428-434.
10. Chen B, Ye B, Zhang J, Ying L, Chen Y (2013) RDW to Platelet Ratio: A Novel Noninvasive Index for Predicting Hepatic Fibrosis and Cirrhosis in Chronic Hepatitis B. PLOS ONE 8: e68780.
11. Erdogan S, Dogan HO, Sezer S, Uysal S, Ozhamam E, et al. (2013) The diagnostic value of non-invasive tests for the evaluation of liver fi brosis in chronic hepatitis B patients. Scandinavian Journal of Clinical & Laboratory Investigation, 73: 300-308.
12. Lin ZH, Xin YN, Dong QJ, Wang Q, Jiang XJ, et al. (2011) Performance of the aspartate aminotransferase-to-platelet ratio index for the staging of hepatitis C-related fibrosis: an updated meta-analysis. Hepatology 53: 726-736.
13. Kim BK, Kim DY, Park JY, Ahn SH, Chon CY, et al. (2010) Validation of FIB-4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus-infected patients. Liver International 30: 546-553.
14. Sterling RK, Lissen E, Clumeck N, Sola R, Correa MC, et al. (2006) Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology 43: 1317-1325. (Pubitemid 43980111)
15. Torriani FJ, Rodriguez-Torres M, Rockstroh JK, Lissen E, Gonzalez-Garcia J, et al. (2004) Peginterferon Alfa-2a plus ribavirin for chronic hepatitis C virus infection in HIV-infected patients. N Engl J Med 351: 438-450. (Pubitemid 38988593)
16. Mallet V, Dhalluin-Venier V, Roussin C, Bourliere M, Pettinelli ME, et al. (2009) The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B. Alimentary Pharmacology & Therapeutics 29: 409-415.
17. Ji D, Shao Q, Han P, Zhang J, Niu X, et al. (2011) Analysis of the efficiency of Fibroscan combined with serologic markers for diagnosing liver fibrosis. Med J Clin PLA 36.
18. Ucar F, Sezer S, Ginis Z, Ozturk G, Albayrak A, et al. (2013) APRI, the FIB-4 score, and Forn's index have noninvasive diagnostic value for liver fibrosis in patients with chronic hepatitis B. European Journal of Gastroenterology & Hepatology 25: 1076-1081.
19. Bonnard P, Sombie R, Lescure F-X, Bougouma A, Guiard-Schmid JB, et al. (2010) Comparison of Elastography, Serum Marker Scores, and Histology for the Assessment of Liver Fibrosis in Hepatitis B Virus (HBV)-Infected Patients in Burkina Faso. American Journal of Tropical Medicine & Hygiene 82: 454-458.
20. Wang H, Xue L, Yan R, Zhou Y, Wang MS, et al. (2013) Comparison of FIB-4 and APRI in Chinese HBV-infected patients with persistently normal ALT and mildly elevated ALT. Journal of Viral Hepatitis 20: e3-e10.
21. Gong H, Hu Y, Ye X, Lin H (2013) Diagnostic efficiency of real-time tissue elastography in evaluating liver fibrosis. ACTA UNIVERSITATIS MEDICINALIS NANJING (Natural Science) 33: 131-134.
22. Zhang Y, Zeng J, Fan Q, Zheng J, Li Q (2012) Four noninvasive score systems for diagnosis of liver fibrosis in patients with chronic hepatitis B. Chin J Clin Infect Dis 5: 338-341.
23. Liu XD, Wu JL, Liang J, Zhang T, Sheng QS (2012) Globulin-platelet model predicts minimal fibrosis and cirrhosis in chronic hepatitis B virus infected patients. World J Gastroenterol 18: 2784-2792.
24. Seto W-K, Lee C-F, Lai C-L, Ip PPC, Fong DY-T, et al. (2011) A New Model Using Routinely Available Clinical Parameters to Predict Significant Liver Fibrosis in Chronic Hepatitis B. PLoS One 6: Article No. e23077.
25. Başar Ö, Yimaz B, Ekiz F, Giniş Z, Altinbaş A, et al. (2013) Non-invasive tests in prediction of liver fibrosis in chronic hepatitis B and comparison with post-antiviral treatment results. Clinics and Research in Hepatology and Gastroenterology 37: 152-158.
26. Wang Y, Xu M-Y, Zheng R-D, Xian J-C, Xu H-T, et al. (2013) Prediction of significant fibrosis and cirrhosis in hepatitis B e-antigen negative patients with chronic hepatitis B using routine parameters. Hepatology Research 43: 441-451.
27. Zhu X, Wang L-C, Chen E-Q, Chen X-B, Chen L-Y, et al. (2011) Prospective Evaluation of FibroScan for the Diagnosis of Hepatic Fibrosis Compared with Liver Biopsy/AST Platelet Ratio Index and FIB-4 in Patients with Chronic HBV Infection. Digestive Diseases & Sciences 56: 2742-2749.
28. Xun Y-h, Zang G-q, Guo J-c, Yu X-l, Liu H, et al. (2013) Serum hepatitis B surface antigen quantification as a useful assessment for significant fibrosis in hepatitis B e antigen-positive hepatitis B virus carriers. Journal of Gastroenterology & Hepatology 28: 1746-1755.
29. Zhu CL, Li WT, Li Y, Gao RT (2012) Serum levels of tissue inhibitor of metalloproteinase-1 are correlated with liver fibrosis in patients with chronic hepatitis B. Journal of Digestive Diseases 13: 558-563.
30. Wu SD, Wang JY, Li L (2010) Staging of liver fibrosis in chronic hepatitis B patients with a composite predictive model: a comparative study. World J Gastroenterol 16: 501-507.
31. Zhang YF, Shi H, Chen LB, Xu QH (2010) Value of FIB-4 for the diagnosis of liver fibrosis in chronic hepatitis B. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 24: 215-217.
32. Zhang Y, Hong D, Bian W, Shen Y, Yan N (2009) Value of FIB-4 for the diagnosis of liver fibrosis in patients with chronic hepatitis B. Ch in J Gastroentero lH epato, 1: 213-214.
33. Batts KP, Ludwig J (1995) Chronic hepatitis. An update on terminology and reporting. Am J Surg Pathol 19: 1409-1417.
34. Scheuer PJ (1991) Classification of chronic viral hepatitis: a need for reassessment. J Hepatol 13: 372-374.
35. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, et al. (1995) Histological grading and staging of chronic hepatitis. J Hepatol 22: 696-699.
36. Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, et al. (2011) QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med 155: 529-536.
37. Lu XL, Xiao ZH, Yang MY, Zhu YM (2013) Diagnostic value of serum procalcitonin in patients with chronic renal insufficiency: a systematic review and meta-analysis. Nephrol Dial Transplant 28: 122-129.
38. Chu H, Cole SR (2006) Bivariate meta-analysis of sensitivity and specificity with sparse data: a generalized linear mixed model approach. J Clin Epidemiol 59: 1331-1332; author reply 1332-1333.
39. Wang F, Gatsonis CA (2008) Hierarchical models for ROC curve summary measures: design and analysis of multi-reader, multi-modality studies of medical tests. Stat Med 27: 243-256. (Pubitemid 351193650)
40. Leeflang MM (2014) Systematic reviews and meta-analyses of diagnostic test accuracy. Clin Microbiol Infect 20: 105-113.
41. Leeflang MM, Deeks JJ, Gatsonis C, Bossuyt PM (2008) Systematic reviews of diagnostic test accuracy. Ann Intern Med 149: 889-897.
42. Zweig MH, Campbell G (1993) Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clinical Chemistry 39: 561-577. (Pubitemid 23118304)
43. Altman DG, Bland JM (1994) Diagnostic tests 3: receiver operating characteristic plots. BMJ 309: 188. (Pubitemid 24216486)
44. Lijmer JG, Bossuyt PM, Heisterkamp SH (2002) Exploring sources of heterogeneity in systematic reviews of diagnostic tests. Stat Med 21: 1525-1537. (Pubitemid 34746061)
45. Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315: 629-634. (Pubitemid 27387172)
46. Duval S, Tweedie R (2000) Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 56: 455-463. (Pubitemid 30422636)
47. Xu M-Y, Qu Y, Jia X-F, Wang M-L, Liu H, et al. (2013) Serum proteomic MRM identify peptide ions of transferrin as new fibrosis markers in chronic hepatitis B. Biomedicine & Pharmacotherapy 67: 561-567.
48. Gumusay O, Ozenirler S, Atak A, Sonmez C, Ozkan S, et al. (2013) Diagnostic potential of serum direct markers and non-invasive fibrosis models in patients with chronic hepatitis B. Hepatology Research 43: 228-237.
49. Wong GLH, Wong VWS, Choi PCL, Chan AWH, Chan HLY (2010) Development of a non-invasive algorithm with transient elastography (Fibroscan) and serum test formula for advanced liver fibrosis in chronic hepatitis B. Alimentary Pharmacology & Therapeutics 31: 1095-1103.
50. Ding D, Meng Z, Ke C, Li D, Chen Y (2013) The Correlation of FIB-4 Index with Child-Pugh Classification in Patients with HBV-related Cirrhosis. J HBUM: 245-247.
51. Zhou J (2013) Application of FibroScan combined with other serologic markers on the diagnosis of liver fibrosis. Int J Lab Med: 409-411.
52. Li X (2012) Developments in hepatic fibrosis diagnosis with the combination of serological indexes and Fibroscan. J Clin Hepatol 15: 472-474.
53. Stibbe KJ, Verveer C, Francke J, Hansen BE, Zondervan PE, et al. (2011) Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients. Scand J Gastroenterol 46: 962-972.
54. Sebastiani G, Castera L, Halfon P, Pol S, Mangia A, et al. (2011) The impact of liver disease aetiology and the stages of hepatic fibrosis on the performance of non-invasive fibrosis biomarkers: an international study of 2411 cases. Aliment Pharmacol Ther 34: 1202-1216.
55. Pissaia A Jr, Borderie D, Bernard D, Scatton O, Calmus Y, et al. (2009) APRI and FIB-4 Scores Are Useful After Liver Transplantation Independently of Etiology. Transplantation Proceedings 41: 679-681.
56. Nalpas B, Mallet V, Vallet-Pichard A, Fontaine H, Pol S (2009) 374 THE FIB-4 INDEX IS ACCURATE TO ASSESS LIVER FIBROSIS BEFORE AND DURING TREATMENT IN CHRONIC HEPATITIS B. Journal of Hepatology 50, Supplement 1: S142-S143.
57. Molto J, Llibre JM, Ribera E, Minguez C, del Rio JS, et al. (2009) Saquinavir exposure in HIV-infected patients with chronic viral hepatitis. Journal of Antimicrobial Chemotherapy 63: 992-997.
58. Lee MH, Cheong JY, Um SH, Seo YS, Kim DJ, et al. (2010) Comparison of Surrogate Serum Markers and Transient Elastography (Fibroscan) for Assessing Cirrhosis in Patients with Chronic Viral Hepatitis. Digestive Diseases & Sciences 55: 3552-3560.
59. Lee JH, Yoon JH, Lee CH, Myung SJ, Keam B, et al. (2009) Complete blood count reflects the degree of oesophageal varices and liver fibrosis in virus-related chronic liver disease patients. Journal of Viral Hepatitis 16: 444-452.
60. Kim BK, Han KH, Park JY, Ahn SH, Chon CY, et al. (2010) External Validation of P2/MS and Comparison with Other Simple Non-invasive Indices for Predicting Liver Fibrosis in HBV-Infected Patients. Digestive Diseases & Sciences 55: 2636-2643.
61. Jain MK, Seremba E, Bhore R, Dao D, Joshi R, et al. (2012) Change in fibrosis score as a predictor of mortality among HIV-infected patients with viral hepatitis. AIDS Patient Care STDS 26: 73-80.
62. de Ledinghen V, Vergniol J, Barthe C, Foucher J, Chermak F, et al. (2013) Non-invasive tests for fibrosis and liver stiffness predict 5-year survival of patients chronically infected with hepatitis B virus. Alimentary Pharmacology & Therapeutics 37: 979-988.
63. Cheong JY, Um SH, Seo YS, Kim DJ, Hwang SG, et al. (2011) Non-invasive index for predicting significant liver fibrosis: comparison of diagnostic performances in patients with chronic hepatitis B and C. Dig Dis Sci 56: 555-563.
64. Beckebaum S, Iacob S, Klein CG, Dechene A, Varghese J, et al. (2010) Assessment of Allograft Fibrosis by Transient Elastography and Noninvasive Biomarker Scoring Systems in Liver Transplant Patients. Transplantation 89: 983-993.
65. Huang YC, Huang CF, Chang KC, Hung SF, Wang JH, et al. (2011) Community-based screening for hepatocellular carcinoma in elderly residents in a hepatitis B- and C-endemic area. J Gastroenterol Hepatol 26: 129-134.
66. Chon YE, Jung ES, Park JY, Kim do Y, Ahn SH, et al. (2012) The accuracy of noninvasive methods in predicting the development of hepatocellular carcinoma and hepatic decompensation in patients with chronic hepatitis B. J Clin Gastroenterol 46: 518-525.
67. Jin W, Lin Z, Xin Y, Jiang X, Dong Q, et al. (2012) Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis B-related fibrosis: a leading meta-analysis. BMC Gastroenterol 12: 14.
68. Castera L, Vergniol J, Foucher J, Le Bail B, Chanteloup E, et al. (2005) Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 128: 343-350. (Pubitemid 40439195)
69. Salkic NN, Jovanovic P, Hauser G, Brcic M (2014) FibroTest/Fibrosure for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis. Am J Gastroenterol 109: 796-809.
70. Chou R, Wasson N (2013) Blood tests to diagnose fibrosis or cirrhosis in patients with chronic hepatitis C virus infection: a systematic review. Ann Intern Med 158: 807-820.
71. Lan X (2012) Study on the area distribution of viral hepatitis in China. Chinese Journal of Health Laboratory Technology: 2467-2469.
72. Dinnes J, Deeks J, Kirby J, Roderick P (2005) A methodological review of how heterogeneity has been examined in systematic reviews of diagnostic test accuracy. Health Technol Assess 9: 1-113, iii.
73. Regev A, Berho M, Jeffers LJ, Milikowski C, Molina EG, et al. (2002) Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection. Am J Gastroenterol 97: 2614-2618.
74. Leeflang MM, Moons KG, Reitsma JB, Zwinderman AH (2008) Bias in sensitivity and specificity caused by data-driven selection of optimal cutoff values: mechanisms, magnitude, and solutions. Clin Chem 54: 729-737. (Pubitemid 351573715)