Nox4 has a crucial role in uric acid-induced oxidative stress and apoptosis in renal tubular cells

Molecular Medicine Reports

Volumn 13, Issue 5, 2016, Pages 4343-4348

  Li, Zhuohang ^a   Sheng, Yiyu ^a   Liu, Cheng ^a   Li, Kuiqing ^a   Huang, Xin ^a   Huang, Jian ^a   Xu, Kewei ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; Nicotinamide adenine dinucleotide phosphate oxidase; Proximal tubular cell; Reactive oxygen species; Uric acid

Indexed keywords

DIPHENYLIODONIUM SALT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; URIC ACID; BAX PROTEIN, HUMAN; BCL2 PROTEIN, HUMAN; NOX4 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL VIABILITY; COCULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; CELL LINE; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; KIDNEY TUBULE; METABOLISM; PHOSPHORYLATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KIDNEY TUBULES; NADPH OXIDASE; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; UP-REGULATION; URIC ACID;

EID: 84964792189     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2016.5083     Document Type: Article

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