DNA Superresolution Structure of Reed-Sternberg Cells Differs between Long-Lasting Remission Versus Relapsing Hodgkin's Lymphoma Patients

Journal of Cellular Biochemistry

Volumn 117, Issue 7, 2016, Pages 1633-1637

  Righolt, Christiaan H ^a   Knecht, Hans ^b   Mai, Sabine ^a,c  

^a UNIVERSITY OF MANITOBA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

DNA STRUCTURE; HODGKIN'S LYMPHOMA; NUCLEAR ARCHITECTURE; STRUCTURED ILLUMINATION MICROSCOPY

Indexed keywords

ADULT; ARTICLE; CANCER CELL; CARCINOGENESIS; CLINICAL ARTICLE; DISEASE COURSE; DNA STRUCTURE; FEMALE; HODGKIN DISEASE; HUMAN; HUMAN CELL; LYMPHOCYTE; LYMPHOCYTE STRUCTURE; MALE; MIDDLE AGED; PRIORITY JOURNAL; REED STERNBERG CELL; YOUNG ADULT; CONFORMATION; METABOLISM; PATHOLOGY; RECURRENT DISEASE; TUMOR CELL LINE;

DNA;

ADULT; CELL LINE, TUMOR; DNA, NEOPLASM; FEMALE; HODGKIN DISEASE; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; NUCLEIC ACID CONFORMATION; RECURRENCE; REED-STERNBERG CELLS;

EID: 84964766309     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.25456     Document Type: Article

References (32)

1. Adebayo Awe J, Xu MC, Wechsler J, Benali-Furet N, Cayre YE, Saranchuk J, Drachenberg D, Mai S,. 2013. Three-dimensional telomeric analysis of isolated circulating tumor cells (CTCs) defines CTC subpopulations. Transl Oncol 6: 51-65.
2. Brousset P, al Saati T, Chaouche N, Zenou RC, Schlaifer D, Chittal S, Delsol G,. 1997. Telomerase activity in reactive and neoplastic lymphoid tissues: Infrequent detection of activity in Hodgkin's disease. Blood 89: 26-31.
3. Cragg GE, So PT,. 2000. Lateral resolution enhancement with standing evanescent waves. Opt Lett 25: 46-48.
4. Drexler HG, Gignac SM, Hoffbrand AV, Minowada J,. 1989. Formation of multinucleated cells in a Hodgkin's-disease-derived cell line. Int J Cancer 43: 1083-1090.
5. Frohn JT, Knapp HF, Stemmer A,. 2000. True optical resolution beyond the Rayleigh limit achieved by standing wave illumination. Proc Natl Acad Sci USA 97: 7232-7236.
6. Guffei A, Sarkar R, Klewes L, Righolt C, Knecht H, Mai S,. 2010. Dynamic chromosomal rearrangements in Hodgkin's lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles. Haematologica 95: 2038-2046.
7. Gustafsson MG,. 2000. Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy. J Microsc 198: 82 - 82-.
8. Hay AE, Meyer RM,. 2014. Balancing risks and benefits of therapy for patients with favorable-risk limited-stage Hodgkin lymphoma: The role of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy alone. Hematol Oncol Clin North Am 28: 49-63.
9. Heine B, Hummel M, Demel G, Stein H,. 1999. Hodgkin and Reed-Sternberg cells of classical Hodgkin's disease overexpress the telomerase RNA template (hTR). J Pathol 188: 139-145.
10. Heintzmann R, Cremer CG., 1999. Proc. SPIE 3568, optical biopsies and microscopic techniques III, 185 (January 19, 1999); doi: 10.1117/12.336833.
11. Hsu SM, Zhao X, Chakraborty S, Liu YF, Whang-Peng J, Lok MS, Fukuhara S,. 1988. Reed-Sternberg cells in Hodgkin's cell lines HDLM, L-428, and KM-H2 are not actively replicating: Lack of bromodeoxyuridine uptake by multinuclear cells in culture. Blood 71: 1382-1389.
12. Johnson NA, Savage KJ, Ludkovski O, Ben-Neriah S, Woods R, Steidl C, Dyer MJ, Siebert R, Kuruvilla J, Klasa R, Connors JM, Gascoyne RD, Horsman DE,. 2009. Lymphomas with concurrent BCL2 and MYC translocations: The critical factors associated with survival. Blood 114: 2273-2279.
13. Jones RJ, Gocke CD, Kasamon YL, Miller CB, Perkins B, Barber JP, Vala MS, Gerber JM, Gellert LL, Siedner M, Lemas MV, Brennan S, Ambinder RF, Matsui W,. 2009. Circulating clonotypic B cells in classic Hodgkin lymphoma. Blood 113: 5920-5926.
14. Kanakry JA, Li H, Gellert LL, Lemas MV, Hsieh WS, Hong F, Tan KL, Gascoyne RD, Gordon LI, Fisher RI, Bartlett NL, Stiff P, Cheson BD, Advani R, Miller TP, Kahl BS, Horning SJ, Ambinder RF,. 2013. Plasma Epstein-Barr virus DNA predicts outcome in advanced Hodgkin lymphoma: Correlative analysis from a large North American cooperative group trial. Blood 121: 3547-3553.
15. Knecht H, Johnson N, Haliotis T, Lichtensztejn D, Mai S,. 2015. Combined 3D immuno-FISH analysis of primary Hodgkin (H) and Reed-Sternberg (RS) cells reveals disruption of telomere-TRF2 interaction and identifies Hodgkin's lymphoma shelterin associated didease. 20th EHA Congress Vienna. Haematologica 100: 105.
16. Knecht H, Kongruttanachok N, Sawan B, Brossard J, Prevost S, Turcotte E, Lichtensztejn Z, Lichtensztejn D, Mai S,. 2012. Three-dimensional telomere signatures of Hodgkin- and Reed- Sternberg cells at diagnosis identify patients with poor response to conventional chemotherapy. Transl Oncol 5: 269-277.
17. Knecht H, Righolt C, Mai S,. 2013. Genomic Instability: The driving force behind refractory/relapsing Hodgkin's lymphoma. Cancers (Basel) 5: 714-725.
18. Knecht H, Sawan B, Lichtensztejn D, Lemieux B, Wellinger RJ, Mai S,. 2009. The 3D nuclear organization of telomeres marks the transition from Hodgkin to Reed-Sternberg cells. Leukemia 23: 565-573.
19. Kuppers R,. 2009. The biology of Hodgkin's lymphoma. Nat Rev Cancer 9: 15-27.
20. Kuppers R, Engert A, Hansmann ML,. 2012. Hodgkin lymphoma. J Clin Invest 122: 3439-3447.
21. Lajoie V, Lemieux B, Sawan B, Lichtensztejn D, Lichtensztejn Z, Wellinger R, Mai S, Knecht H,. 2015. LMP1 mediates multinuclearity through downregulation of shelterin proteins and formation of telomeric aggregates. Blood 125: 2101-2110.
22. Luengo Hendriks CL, Rieger B, van Ginkel M, van Kempen GMP, van Vliet LJ,. 1999. DIPimage: A scientific image processing toolbox for MATLABeditor^editors. Delft University of Technology.
23. Luengo Hendriks CL, van Kempen GMP, van Vliet LJ,. 2007. Improving the accuracy of isotropic granulometries. Pattern Recognit Lett 28: 865-872.
24. MacLeod RA, Spitzer D, Bar-Am I, Sylvester JE, Kaufmann M, Wernich A, Drexler HG,. 2000. Karyotypic dissection of Hodgkin's disease cell lines reveals ectopic subtelomeres and ribosomal DNA at sites of multiple jumping translocations and genomic amplification. Leukemia 14: 1803-1814.
25. Newcom SR, Kadin ME, Phillips C,. 1988. L-428 Reed-Sternberg cells and mononuclear Hodgkin's cells arise from a single cloned mononuclear cell. Int J Cell Cloning 6: 417-431.
26. Norrback KF, Enblad G, Erlanson M, Sundstrom C, Roos G,. 1998. Telomerase activity in Hodgkin's disease. Blood 92: 567-573.
27. Righolt CH, Guffei A, Knecht H, Young IT, Stallinga S, van Vliet LJ, Mai S,. 2014. Differences in nuclear DNA organization between Lymphocytes, Hodgkin and Reed-Sternberg Cells revealed by structured illumination microscopy. J Cell Biochem 115: 1441-1448.
28. Sathitruangsak C, Righolt CH, Klewes L, Tammur P, Ilus T, Tamm A, Punab M, Olujohungbe A, Mai S,. 2015. Quantitative superresolution microscopy reveals differences in nuclear DNA organization of multiple myeloma and monoclonal gammopathy of undetermined significance. J Cell Biochem 116: 704-710.
29. Steidl C, Diepstra A, Lee T, Chan FC, Farinha P, Tan K, Telenius A, Barclay L, Shah SP, Connors JM, van den Berg A, Gascoyne RD,. 2012. Gene expression profiling of microdissected Hodgkin Reed-Sternberg cells correlates with treatment outcome in classical Hodgkin lymphoma. Blood 120: 3530-3540.
30. Szczurek AT, Prakash K, Lee HK, Zurek-Biesiada DJ, Best G, Hagmann M, Dobrucki JW, Cremer C, Birk U,. 2014. Single molecule localization microscopy of the distribution of chromatin using Hoechst and DAPI fluorescent probes. Nucleus 5: 331-340.
31. Wang Y, Maharana S, Wang MD, Shivashankar GV,. 2014. Super-resolution microscopy reveals decondensed chromatin structure at transcription sites. Sci Rep 4: 4477.
32. Young IT, Gerbrands JJ, Van Vliet LJ,. 1998. Image Processing Fundamentals. In:, Madisetti VK, Williams DB, editors. The digital signal processing handbook. Boca Raton, Florida: CRC Press in cooperation with IEEE Press. pp 51.51-51.81.