Time lapse in vivo microscopy reveals distinct dynamics of microglia-tumor environment interactions-a new role for the tumor perivascular space as highway for trafficking microglia

GLIA

Volumn 64, Issue 7, 2016, Pages 1210-1226

  Bayerl, Simon Heinrich ^a   Niesner, Raluca ^b   Cseresnyes, Zoltan ^b   Radbruch, Helena ^a   Pohlan, Julian ^b   Brandenburg, Susan ^a   Czabanka, Marcus Alexander ^a   Vajkoczy, Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b German Rheumatism Research Center Berlin   (Germany)

Author keywords

2 photon microscopy; Angiogenesis; Glioma; Microglia motility; NADPH oxidase

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; ENHANCED GREEN FLUORESCENT PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUNITINIB; CX3CR1 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; KI 67 ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL ACTIVITY; CELL FUNCTION; CELL INTERACTION; CELL MIGRATION; CELL MOTILITY; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; GLIOMA; IMAGING SOFTWARE; IN VIVO STUDY; INTRAVITAL EPI ILLUMINATING FLUORESCENCE VIDEO MICROSCOPY; INTRAVITAL MICROSCOPY; LASER MICROSCOPY; MICROGLIA; MOLECULAR DYNAMICS; MOUSE; MOUSE MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PERIVASCULAR SPACE; PHENOTYPE; PRIORITY JOURNAL; REDUCTION; TUMOR MICROENVIRONMENT; TUMOR MODEL; TWO PHOTON LASER SCANNING MICROSCOPY; VASCULAR TUMOR; VIDEO MICROSCOPY; ANIMAL; BRAIN TUMOR; C57BL MOUSE; CELL MOTION; CONFOCAL MICROSCOPY; DIAGNOSTIC IMAGING; DISEASE MODEL; DRUG SCREENING; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; IMAGE PROCESSING; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CX3C CHEMOKINE RECEPTOR 1; DISEASE MODELS, ANIMAL; GENE-ENVIRONMENT INTERACTION; GLIOMA; GREEN FLUORESCENT PROTEINS; IMAGE PROCESSING, COMPUTER-ASSISTED; INTRAVITAL MICROSCOPY; KI-67 ANTIGEN; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MICROSCOPY, CONFOCAL; NADP; NEOVASCULARIZATION, PATHOLOGIC; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84964754235     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22994     Document Type: Article

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