MicroRNA-335-5p inhibits osteoblast apoptosis induced by high glucose

Molecular Medicine Reports

Volumn 13, Issue 5, 2016, Pages 4108-4112

  Li, Jiling ^a   Feng, Zhengping ^a   Chen, Lixue ^a   Wang, Xiaoju ^a   Deng, Huacong ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Dickkopf 1; MicroRNA 335 5p; Osteoblast

Indexed keywords

CASPASE 3; DICKKOPF 1 PROTEIN; GLUCOSE; MICRORNA; MICRORNA 335 5P; UNCLASSIFIED DRUG; DKK1 PROTEIN, MOUSE; MIRN335 MICRORNA, MOUSE; SIGNAL PEPTIDE;

APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; DIABETIC OSTEOPOROSIS; DOWN REGULATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; OSTEOBLAST; OSTEOPOROSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; MOUSE;

ANIMALS; APOPTOSIS; CELL LINE; GENE EXPRESSION REGULATION; GLUCOSE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICRORNAS; OSTEOBLASTS;

EID: 84964754030     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2016.4994     Document Type: Article

References (25)

1. Wittrant Y, Gorin Y, Woodruff K, Horn D, Abboud HE, Mohan S and Abboud-Werner SL: High d (+) glucose concentration inhibits RANKL-induced osteoclastogenesis. Bone 42:1122-1130, 2008.
2. Bartel DP: MicroRNAs: Genomics, biogenesis, mechanism and function. Cell 116:281-297, 2004.
3. Mattick JS and Makunin IV: Non-coding RNA. Hum Mol Genet 1:R17-R29, 2006.
4. Huntzinger E and Izaurralde E: Gene silencing by microRNAs: Contributions of translational repression and mRNA decay. Nat Rev Genet 12:99-110, 2011.
5. Ciesla M, Skrzypek K, Kozakowska M, Loboda A, Jozkowicz A and Dulak J: MicroRNAs as biomarkers of disease onset. Anal Bioanal Chem 401:2051-2061, 2011.
6. Song L and Tuan RS: MicroRNAs and cell differentiation in mammalian development. Birth Defects Res C Embryo Today 78:140-149, 2006.
7. Davis BN and Hata A: Regulation of MicroRNA Biogenesis: A miRiad of mechanisms. Cell Commun Signal 7:18, 2009.
8. Stern-Ginossar N, Elefant N, Zimmermann A, Wolf DG, Saleh N, Biton M, Horwitz E, Prokocimer Z, Prichard M, Hahn G, et al: Host immune system gene targeting by a viral miRNA. Science 317:376-381, 2007.
9. Shu M, Zheng X, Wu S, Lu H, Leng T, Zhu W, Zhou Y, Ou Y, Lin X, Lin Y, et al: Targeting oncogenic MIR-335 inhibits growth and invasion of malignant astrocytoma cells. Mol Cancer 10:59, 2011.
10. Zhang J, Tu Q, Bonewald LF, He X, Stein G, Lian J and Chen J: Effects of MIR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1. J Bone Miner Res 26:1953-1963, 2011.
11. Hu Z, Wang B, Cao X, Du T and Zhang S: Prediction of micro-RNA related to change of mouse osteoblast function under simulated microgravity with bioinformatics method. Space Med Med Eng 25:407-411, 2012 (In Chinese).
12. Sato N, Yamabuki T, Takano A, Koinuma J, Aragaki M, Masuda K, Ishikawa N, Kohno N, Ito H, Miyamoto M, et al: Wnt inhibitor Dickkopf-1 as a target for passive cancer immunotherapy. Cancer Res 70:5326-5336, 2010.
13. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) Method. Methods 25:402-408, 2001.
14. Jackuliak P and Payer J: Osteoporosis, fractures, and diabetes. Int J Endocrinol 2014:820615, 2014.
15. Marie PJ: Osteoblast dysfunctions in bone diseases: From cellular and molecular mechanisms to therapeutic strategies. Cell Mol Life Sci 72:1347-1361, 2015.
16. Li H, Xie S, Liu M, Chen Z, Liu X, Wang L, Li D and Zhou Y: The clinical significance of downregulation of mir-124-3p, mir-146a-5p, mir-155-5p and mir-335-5p in gastric cancer tumorigenesis. Int J Oncol 45:197-208, 2014.
17. Cui XS, Sun SC, Kang YK and Kim NH: Involvement of microRNA-335-5p in cytoskeleton dynamics in mouse oocytes. Reprod Fertil Dev 25:691-699, 2013.
18. Oger F, Gheeraert C, Mogilenko D, Benomar Y, Molendi-Coste O, Bouchaert E, Caron S, Dombrowicz D, Pattou F, Duez H, et al: Cell-specific dysregulation of microRNA expression in obese white adipose tissue. J Clin Endocrinol Metab 99:2821-2833, 2014.
19. Zhang J, Zhu X, Cui J, Chen P, Wang S and Wang J: Differential expressions of microRNA between young and senescent endothelial cells. Chin Med J 92:2205-2209, 2012 (In Chinense).
20. Ertekin S, Yildirim O, Dinç E, Ayaz L, Fidanci SB and Tamer L: Evaluation of circulating miRNAs in wet age-related macular degeneration. Mol Vis 20:1057-1066, 2014.
21. Wang XJ, Feng ZP, Deng HC, Jiang R and Du J: Effect of AP-1 on apoptosis of MC3T3-E1 osteoblast induced by high-glucose. Zhong Hua Gu Zhi Shu Song He Gu Kuang Yan Ji Bing Za Zhi 7:258-262, 2014 (In Chinese).
22. Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, et al: Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone 39:754-766, 2006.
23. Morvan F, Boulukos K, Clément-Lacroix P, Roman Roman S, Suc-Royer I, Vayssière B, Ammann P, Martin P, Pinho S, Pognonec P, et al: Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass. J Bone Miner Res 21:934-945, 2006.
24. Qiang YW, Barlogie B, Rudikoff S and Shaughnessy JD Jr: Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma. Bone 42:669-680, 2008.
25. Wang LF, Bai D and Han XL: Progress in Dickkopf-1-mediated bone metabolism. J Clin Rehabil Tissue Eng Res 17:337-341, 2013 (In Chinese).